Texas Medical Center Holidays from £1,103

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £335 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Texas Medical Centre Holiday

Our Texas Medical Centre holiday packages are a speedy and practical way to plan and reserve your next adventure. Discover the true character of this unique neighbourhood without the pressure of planning it all yourself. Start your trip to Texas Medical Centre by heading to nearby attractions such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. No matter what your dream Texas Medical Centre holiday may look like, you can turn it into reality with Expedia.

Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Houston Heights I-10

Hampton Inn & Suites Houston Heights I-10

2.5 out of 5
Washington Ave./ Memorial Park
Price was £1,251, price is now £1,103 per person
£1,103
per person
2 Apr - 6 Apr
found 1 day ago
Return flight included
London (LON) to Houston (IAH)
9/10 Wonderful! (1,003 reviews)
Very clean room, very clean hotel, very courteous staff

Reviewed on 8 Feb 2026

The Lancaster Hotel

The Lancaster Hotel

4 out of 5
Downtown Houston
Price was £1,652, price is now £1,391 per person
£1,391
per person
13 Mar - 16 Mar
found 1 day ago
Return flight included
Manchester (MAN) to Houston (IAH)
9.8/10 Exceptional! (1,004 reviews)
Amazing staff! Looking forward to staying there as gain

Reviewed on 8 Feb 2026

Le Meridien Houston Downtown

Le Meridien Houston Downtown

4 out of 5
Downtown Houston
Price was £1,470, price is now £1,269 per person
£1,269
per person
2 Apr - 6 Apr
found 1 day ago
Return flight included
London (LON) to Houston (IAH)
8.8/10 Excellent! (1,005 reviews)
The stay was great !

Reviewed on 8 Feb 2026

La Colombe d'Or Hotel

La Colombe d'Or Hotel

5 out of 5
Montrose
Price was £1,629, price is now £1,427 per person
£1,427
per person
13 Mar - 16 Mar
found 1 day ago
Return flight included
Manchester (MAN) to Houston (IAH)
9.2/10 Wonderful! (136 reviews)
Bungalows are so gorgeous! One of the best hotels I’ve stayed at years! Cocktails are also delicious! Have very few reasons to be in Houston, but would plan a trip just to stay in this hotel again!

Reviewed on 6 Feb 2026

Paradise Palace Best Rooftop in HTX w Hot Tub

Paradise Palace Best Rooftop in HTX w Hot Tub

3 out of 5
Southeast Houston
Price was £2,997, price is now £2,662 per person
£2,662
per person
13 Mar - 16 Mar
found 1 day ago
Return flight included
Manchester (MAN) to Houston (IAH)
No reviews

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

Find hotels in Downtown Houston

Top hotels in Texas Medical Center

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
The price is £160 per night from 16 Feb to 17 Feb
£160
16 Feb - 17 Feb
includes taxes & fees
9/10 Wonderful! (3,722 reviews)
Great hotel!

Reviewed on 7 Feb 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is £75 per night from 22 Feb to 23 Feb
£75
22 Feb - 23 Feb
includes taxes & fees
8.4/10 Very Good! (1,831 reviews)
Clean room, attentive and friendly staff, good resources

Reviewed on 4 Feb 2026

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
The price is £109 per night from 15 Feb to 16 Feb
£109
15 Feb - 16 Feb
includes taxes & fees
9/10 Wonderful! (2,304 reviews)
Clean room and staff

Reviewed on 3 Feb 2026

Hyatt Place Houston Medical Center
See all 6,614 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Texas Medical Centre travel package cost?
Cross off another part of the world with our Texas Medical Centre travel packages, which start from just £1,103. Choose the flights and hotels that fit your travel plans. Then, add on one or two sightseeing activities to round off your unique escape.
If I'm not able to travel, can I cancel my Texas Medical Centre travel package?
Certainly, and we'll help you every step of the way. You may be able to cancel and rebook your Texas Medical Centre travel package for free if you booked in the last 24 hours. But you may be charged a fee by your hotel, airline or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, browse our Customer Service Portal for further information.
How do I get a cheap travel package to Texas Medical Centre?
Browse and lock in everything all in one place with our Texas Medical Centre travel packages. We have incredible bargains on hotels, flights, tours and more that'll keep your pocketbook happy and your adventurous spirit alive. And, with more than 550 partner airlines and 1,000,000 hotels globally to pick from, there are endless opportunities to mix and match however you please.
Does Expedia offer Book Now, Pay Later Texas Medical Centre holidays?
Your bank balance shouldn't get in the way of going on holiday, so Expedia has devised a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book a dream getaway without eating away at your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: Klarna offers manageable monthly payment plans that fit all budgets, so you can have that well-deserved holiday sooner.
  • Pay in instalments holidays: If you'd prefer to pay for your getaway in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Clicking on the "book now" button is much easier with this option. Just put down a small deposit on your escape and then start packing your bags.

Where should I stay in Texas Medical Centre?
Urban explorers come from all corners of the globe to experience Johnson Space Centre - NASA and Toyota Centre in Texas Medical Centre. Stay within a stone's throw of these popular attractions and visit them at your leisure.
What are the top hotels in Texas Medical Centre?
Doubletree By Hilton Houston Medical Centre Hotel And Suites and The Whitehall Houston are a couple of the most sought-after properties in Texas Medical Centre. Why not take a look at the facilities and amenities at each and then decide?
How far in advance should I book my Texas Medical Centre holiday?
It can be tricky to know exactly when is the perfect time to book your Texas Medical Centre holiday. But generally the earlier you book, the more affordable the prices. Sometimes, you can secure your flights and hotels nearly 12 months prior to departure. If you're considering a last-minute getaway, no need to stress! There are plenty of fantastic deals popping up on Expedia every day.
What does an Expedia Texas Medical Centre travel package include?
Rental cars, hotels and flights, or any combination of them — the choice is all yours! Whether you're venturing to Texas Medical Centre with the whole family or adventuring with your friends, there's a bundle to match every budget and style. Once you've made your booking, why not add on one or two activities?
What should I know before booking a Texas Medical Centre travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and score exciting discounts. Hotels aren't your only option, though. We've got beachfront villas, rural cottages and even castles and houseboats!
Can I choose my airline with a Texas Medical Centre Expedia travel package?
Yes, you're in control. We have access to over 550 partner airlines all over the world, so you can customize your Texas Medical Centre trip according to your travel preferences.

Popular places to visit

MD Anderson Cancer Center

4/5(1 review)

If MD Anderson Cancer Center is what brings you to town, hopefully you'll have a chance to explore more of Houston.

MD Anderson Cancer Center

Things to do

The Official Houston City Tour

NASA's Space Center Admission Plus Houston City Tour

£80
per adult
92% of travellers recommend
NASA's Space Center Admission Plus Houston City Tour
Houston: Houston Botanic Garden Entry Ticket

Houston: Houston Botanic Garden Entry Ticket

£9
per adult
80% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
Astroville Tunnel Tour of Downtown Houston

Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)

£19
per adult
100% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
See all activities in Houston

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.