Title: All Hotels by La Quinta Inn & Suites in Southwest Illinois - 2025 Updated Prices | Expedia.co.uk [Southwest Illinois Travel Guide](https://expedia.co.uk/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Holiday Rentals in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Holiday-Rentals.d6058943.Travel-Guide-HolidayRentals)[Flights to Southwest Illinois](https://expedia.co.uk/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Southwest Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Illinois.d6058943.Car-Hire-Guide)[Southwest Illinois Holidays](https://expedia.co.uk/Southwest-Illinois.d6058943.Holidays-City-Breaks) ![Southern Illinois which includes a lake or waterhole and forest scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208715-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by La Quinta Inn & Suites in Southwest Illinois from £58 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [8 Oct - 9 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Oct - 10 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southwest Illinois La Quinta Inn & Suites Hotels ![Lobby](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/8a97f90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/9e2bab0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/54a98b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/432f70f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Collinsville - St. Louis Eastport 7.2/10 Good (1006) "We had a great experience here! " £71 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, pillow-top beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/079daa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/058a5631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/1a232cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis O'Fallon 6.0/10 (1003) "Enjoyed The Pool" £58 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/dfd22323.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility Accessible) | Premium bedding, down duvets, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/7068f006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/9075cfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/b9aaaeee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Pontoon Beach Granite City 7.8/10 Good (498) "The staff here was superb!" £72 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pontoon-Beach.h424254.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23®ionId=6058943&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-La-Quinta-Inn-Suites.0-0-d6058943--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-La-Quinta-Inn-Suites.0-0-d6058943--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Southwest Illinois Hotel Reviews ![Drury Inn & Suites Marion](//images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Exceptional people with exceptional services" [](https://expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Drury Inn & Suites St. Louis Collinsville](//images.trvl-media.com/lodging/1000000/50000/42100/42035/fff178d6_y.jpg) ### Drury Inn & Suites St. Louis Collinsville 10/10 Excellent "Parking lot feeling safe, light well. staff very friendly, free coffee and soft drink 24 hours, very impressive about that. will stay again if go that area. " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Collinsville.h42035.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](//images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "The staff is professional and courteous. The room is very clean. The property is well kept. Restaurants are within walking distant. It’s pet friendly." [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Comfort Suites Mount Vernon](//images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Pool open to adults 24 hrs if quiet" [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Best Western Plus Pontoon Beach](//images.trvl-media.com/lodging/3000000/2700000/2695400/2695352/01153352_y.jpg) ### Best Western Plus Pontoon Beach 10/10 Excellent "Very friendly and clean . Very nice place to stay in the area we were !!! " [](https://expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-Pontoon-Beach.h2695352.Hotel-Information) ![The Principal Hotel](//images.trvl-media.com/lodging/107000000/106860000/106856200/106856168/5d07ff1f_y.jpg) ### The Principal Hotel 10/10 Excellent "Always nice here. 3rd trip " [](https://expedia.co.uk/Columbia-Hotels-The-Principal-Hotel.h106856168.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](//images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Check in staff was friendly and prompt. Room is clean and spacious." [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](//images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Clean. A little noisy at late hours but not disturbing " [](https://expedia.co.uk/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Super 8 by Wyndham O'Fallon](//images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "The staff were very nice." 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