Title: All Hotels by La Quinta Inn & Suites in Southwest Illinois - 2026 Updated Prices | Expedia.co.uk [Southwest Illinois Travel Guide](https://expedia.co.uk/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Holiday Rentals in Southwest Illinois](https://expedia.co.uk/Southwest-Illinois-Holiday-Rentals.d6058943.Travel-Guide-HolidayRentals)[Flights to Southwest Illinois](https://expedia.co.uk/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Southwest Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Illinois.d6058943.Car-Hire-Guide)[Southwest Illinois Holidays](https://expedia.co.uk/Southwest-Illinois.d6058943.Holidays-City-Breaks) ![One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Carl Anderson # Search Hotels by La Quinta Inn & Suites in Southwest Illinois from £39 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Jan - 8 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058943&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southwest Illinois La Quinta Inn & Suites ![Exterior](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/67c9e775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/694c14fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/54a98b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9650000/9642800/9642754/5bb8e5d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Collinsville - St. Louis [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) Eastport 7.2/10 Good (1005) "Everything was nice and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Avanjanae £71 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Collinsville-St-Louis.h9642754.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/c5041840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/058a5631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/a9eaceec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, pillow-top beds, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/210000/201300/201286/079daa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) O'Fallon 6.0/10 (1000) "Clean bed and room. Very nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nita £39 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Collinsville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-OFallon.h201286.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/8731eb68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/f969f8e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Premium bedding, down duvets, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/1120bfaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/430000/424300/424254/f9ce5b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Pontoon Beach [](https://www.expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pontoon-Beach.h424254.Hotel-Information) Granite City 7.6/10 Good (515) "The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kari £76 includes taxes & fees 8 Jan - 9 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pontoon-Beach.h424254.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-21&endDate=2026-01-22®ionId=6058943&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-La-Quinta-Inn-Suites.0-0-d6058943--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouthwest-Illinois-Hotels-La-Quinta-Inn-Suites.0-0-d6058943--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) ## Top Southwest Illinois Hotel Reviews ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "The staff was very friendly and the room looked fantastic " [](https://expedia.co.uk/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Courteous staff, great breakfast and reasonable rates! " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Great stay" [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Polite Staff, the room was Great and Very Clean. Would recommend to anyone to stay With Drury Hotels!!!" [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Welcoming, clean, very pet friendly " [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](https://images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Amazing hotel. Price is fare. Renovated, clean spacious, friendly staff, well organized. Would recommend!!!! Thank You so much!!!! " [](https://expedia.co.uk/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Staff was great, rooms where clean and breakfast was good " [](https://expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Baymont by Wyndham O'Fallon St. Louis Area](https://images.trvl-media.com/lodging/1000000/70000/60700/60642/a4ff32db_y.jpg) ### Baymont by Wyndham O'Fallon St. Louis Area 10/10 Excellent "Nice room good price " [](https://expedia.co.uk/Collinsville-Hotels-Baymont-By-Wyndham-OFallon-St-Louis-Area.h60642.Hotel-Information) ![Country Inn & Suites by Radisson, Fairview Heights, IL](https://images.trvl-media.com/lodging/1000000/20000/19300/19224/54968ac9_y.jpg) ### Country Inn & Suites by Radisson, Fairview Heights, IL 10/10 Excellent "Clean and newly renovated rooms. Breakfast was standard- cereal, muffins, and waffles. 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