Title: TOP Adults Only Resorts & Hotels in Southwest Coast Florida, FL for 2026 | Expedia.co.uk [Southwest Coast Florida Travel Guide](https://expedia.co.uk/Southwest-Coast-Florida.dx6048100)[Hotels in Southwest Coast Florida](https://expedia.co.uk/Southwest-Coast-Florida-Hotels.d6048100.Travel-Guide-Hotels)[Holiday Rentals in Southwest Coast Florida](https://expedia.co.uk/Southwest-Coast-Florida-Holiday-Rentals.d6048100.Travel-Guide-HolidayRentals)[Flights to Southwest Coast Florida](https://expedia.co.uk/Cheap-Flights-To-Southwest-Coast-Florida.d6048100.Travel-Guide-Flights)[Southwest Coast Florida Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southwest-Coast-Florida.d6048100.Car-Hire-Guide)[Southwest Coast Florida Holidays](https://expedia.co.uk/Southwest-Coast-Florida.d6048100.Holidays-City-Breaks) ![Fort Myers Beach featuring a sunset, a bridge and a beach](https://images.trvl-media.com/place/7194/a3a41af4-04ff-4ed9-8a12-4ad5a2acfee2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Adults Only Resorts & Hotels in Southwest Coast Florida - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Coast Florida Adults Only Resorts & Hotels Tonight [6 Jan - 7 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6048100&startDate=2026-01-06&endDate=2026-01-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [7 Jan - 8 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6048100&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6048100&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6048100&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Our top choices for Southwest Coast Florida adults-only hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/457600/457582/e50473e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, white sand, free beach shuttle, sun-loungers](https://images.trvl-media.com/lodging/1000000/460000/457600/457582/ed7dedc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/460000/457600/457582/e7cb8693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | View from room](https://images.trvl-media.com/lodging/1000000/460000/457600/457582/23b10049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Escalante [](https://www.expedia.co.uk/Naples-Hotels-The-Escalante.h457582.Hotel-Information) Old Naples 9.2/10 Wonderful (130) "Beautiful space and location is perfection " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janelle £1,006 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Naples-Hotels-The-Escalante.h457582.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/96000000/95420000/95417800/95417780/0834c956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/96000000/95420000/95417800/95417780/85d78e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 9:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/96000000/95420000/95417800/95417780/15bd74cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/96000000/95420000/95417800/95417780/8ab3f8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mari Jean Hotel - All Adults Welcome [](https://www.expedia.co.uk/St-Petersburg-Clearwater-Hotels-Mari-Jean-Hotel.h95417780.Hotel-Information) Historic Kenwood 8.8/10 Excellent (345) "Everything in the establishment was amazing. Emilia was so helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elena £88 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/St-Petersburg-Clearwater-Hotels-Mari-Jean-Hotel.h95417780.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-20&endDate=2026-01-21®ionId=6048100&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southwest Coast Florida ### Discover top Southwest Coast Florida attractions Southwest Coast Florida offers an exquisite blend of natural beauty and family-friendly activities that will delight the Quality Seeker. Start your adventure at the stunning beaches of Sanibel Island, where the soft sandy shores are perfect for shell collecting – a favourite pastime for both children and adults alike. Next, explore the lush landscapes of the J.N. "Ding" Darling National Wildlife Refuge, where you can embark on a guided kayak tour to witness the diverse wildlife up close, including manatees and a variety of bird species. For a taste of local culture, visit the vibrant shops and art galleries in downtown Naples, where you can indulge in exquisite dining options that cater to discerning palates. Families will love the interactive exhibits at the Imaginarium Science Center in Fort Myers, sparking curiosity and creativity in children of all ages. After a day of exploration, consider staying in the luxurious resorts along the coastline in Naples, where attentive service and upscale amenities create a pampered experience. The combination of pristine beaches and world-class hospitality makes this area an exciting base for your Southwest Florida adventure. ## Top Southwest Coast Florida Hotel Reviews ![Naples Grande Beach Resort](https://images.trvl-media.com/lodging/1000000/20000/15900/15898/65da812e_y.jpg) ### Naples Grande Beach Resort 10/10 Excellent "Room was very nice. Really appreciated the grown-ups only pool. Beach was a short golf cart drive away. Menu was accessible for my entire family." [](https://expedia.co.uk/Naples-Hotels-Naples-Grande-Beach-Resort.h15898.Hotel-Information) ## Frequently asked questions ### How much do adults-only hotels in Southwest Coast Florida cost? ### How can I find cheap adults-only hotels in Southwest Coast Florida? ### From what age can you stay in an adult-only hotel in Southwest Coast Florida? ### Are all adult-only resorts all-inclusive in Southwest Coast Florida? ### Why book your adults-only hotel in Southwest Coast Florida with Expedia? ### When is the best time to stay at an adult-only all-inclusive resort in Southwest Coast Florida? ### Can I cancel or change my adult-only resort booking? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Fort Myers ](https://www.expedia.co.uk/5Star-Fort-Myers-Hotels.s50-0-d602729.Travel-Guide-Filter-Hotels) - [Broadview Manor Hotels ](https://www.expedia.co.uk/Broadview-Manor-Fort-Myers-Hotels.0-n553248635976473572-0.Travel-Guide-Filter-Hotels) - 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