Title: The Best Hotels in Southhampton, St. Louis - 2025 Updated Prices | Expedia.co.uk [Holiday Rentals in St. Louis](https://expedia.co.uk/St-Louis-Holiday-Rentals.d178309.Travel-Guide-HolidayRentals)[Flights to St. Louis](https://expedia.co.uk/Cheap-Flights-To-St-Louis.d178309.Travel-Guide-Flights)[Things to do in St. Louis](https://expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities)[Southhampton Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southhampton.d553248635975872889.Car-Hire-Guide)[Southhampton Holidays](https://expedia.co.uk/Southhampton.d553248635975872889.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Southhampton, St. Louis ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Southhampton Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&lodging=CONDO) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Southhampton%2C+St.+Louis%2C+Missouri%2C+United+States+of+America®ionId=553248635975872889&latLong=38.587406%2C-90.284918&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=WATER_PARK) ## Check prices for these dates Tonight [26 Sept - 27 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872889&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872889&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872889&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872889&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Southhampton, St. Louis ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/532a2ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/3c6c1cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e2ffcacf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel St. Louis at the Arch Downtown St. Louis, 5.8 mi from Southhampton 9.4/10 Exceptional (3095) "Great staff and food " £104 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/4d0e3d47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/1ed98bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Refrigerator & Microwave | Desk, blackout curtains, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/5436fdea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Airport 11.5 mi from Southhampton 9.4/10 Exceptional (2694) "Nice place to stay " £79 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/fde81462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/a847bb13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/1dea3ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis Union Station Downtown West, 4.9 mi from Southhampton 9.4/10 Exceptional (1259) " Love staying here!" £105 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/3721d666.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/542563f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/e4de4f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency St. Louis at The Arch Downtown St. Louis, 5.9 mi from Southhampton 8.4/10 Very good (4016) "Close to all events great stay" £110 includes taxes & fees 2 Oct - 3 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c85b5876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/446bd1a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10.3 mi from Southhampton 8.2/10 Very good (1035) "The staff was nice, breakfast was good, the location was convenient. " £77 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/fe8445aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, City View | 1 bedroom, Egyptian cotton sheets, premium bedding, pillow-top beds](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/ff34bd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel 4.8 mi from Southhampton 9.0/10 Wonderful (1905) "Food on the rooftop was amazing " £127 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/66ab3de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/1893bab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wildwood Hotel 18.6 mi from Southhampton 9.2/10 Wonderful (1599) "We enjoyed our stay!" £80 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/f94bc4e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/c9cba8d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/c451f767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18200/18172/2ae439f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham St. Louis Airport 11.5 mi from Southhampton 9.2/10 Wonderful (1427) "Very clean and friendly staff" £100 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Wingate-By-Wyndham-St-Louis-Airport.h18172.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/fbc44c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft, 2 Queen Beds | 1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cfb8ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/fb7f173e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21C Museum Hotel St Louis Downtown West, 5.4 mi from Southhampton 9.0/10 Wonderful (1388) "Wonderful stay! " £135 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/4e0535c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d86dad87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed with Sofa bed, Non Smoking (Conference) | Living area | 50-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/8c007982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton St. Louis Downtown Downtown St. Louis, 5.9 mi from Southhampton 8.8/10 Excellent (1230) "Clean quiet rooms and friendly staff!" £110 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/500/422/w2883h1805x9y0-d898bd46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/10000/500/422/8a55f8f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/500/422/d1343ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sonesta ES Suites St. Louis - Chesterfield 15.1 mi from Southhampton 8.0/10 Very good (1017) "Very nice place" £75 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/b3c5d3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/13e26dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/a7d1479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, a heated pool, open 10:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/fd2b191b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clayton Plaza Hotel & Extended Stay 5.1 mi from Southhampton 8.8/10 Excellent (2971) "Great staff and hotel!" £87 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/e7e4aca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/3aed884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite, 1 King Bed | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/62321a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Live by Loews - St.Louis Downtown St. Louis, 5.5 mi from Southhampton 9.2/10 Wonderful (1059) "Great quick stay!" £149 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d33a8d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/ef39d78c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/5c9c1d9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/40200/40112/d7498121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn St. Louis Arnold 11.1 mi from Southhampton 9.2/10 Wonderful (1016) "Clean, comfortable and pleasant stay." £77 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Arnold.h40112.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/4e2b8726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Non Smoking (Walk-in Shower) | 1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/b7be62e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/b2be25f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus St. Louis West-Westport 12.3 mi from Southhampton 8.0/10 Very good (1016) "It was a very nice place" £76 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/ef209186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 10:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/2811db1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/w1020h682x1y0-97f5900d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cheshire 3.4 mi from Southhampton 8.6/10 Excellent (1012) "Great staff, wonderful property." £119 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/4a44ac13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/32af9b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/1aa074ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/106000000/105380000/105374500/105374473/5625286c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel St. Louis Clayton 5 mi from Southhampton 9.2/10 Wonderful (186) "Enjoyed my stay" £107 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Ac-Hotel-By-Marriott-St-Louis-Clayton.h105374473.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rodeo Junior Suite, 1 King Bed | 1 bedroom, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/b33425c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/cb1b5cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hollywood Casino & Hotel St. Louis 15.6 mi from Southhampton 8.4/10 Very good (2168) "Great stay!" £87 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68000/67904/4aa76c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/70000/68000/67904/f9b83168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking | Bathroom | Free toiletries, hair dryer](https://images.trvl-media.com/lodging/1000000/70000/68000/67904/d9a69550.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/68000/67904/e186deec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham St. Louis 10.3 mi from Southhampton 6.6/10 (1028) "Just did an overnight stay and everything was great! " £56 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-Travelodge-By-Wyndham-St-Louis.h67904.Hotel-Information) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/33f9207d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/4addfd67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/567f1c22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/f521c6f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River City Casino & Hotel 4.1 mi from Southhampton 9.0/10 Wonderful (1390) "Place was nice and staff was very friendly " £87 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=553248635975872889&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Southhampton Find the best Southhampton areas for the activities you enjoy most. - Downtown St. Louis - Clayton - Central West End - Creve Coeur - St. Charles Historic District ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478676-St-Louis-City-Missouri.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199593-Saint-Louis.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478695-St-Louis-City-Missouri.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479138-Downtown-St-Louis.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478696-St-Louis-City-Missouri.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800136) ![Downtown St. Louis map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:evujFtopePcu%40wTsp%40oPxHuq%40v%40kAXiDwC%40QmDpCul%40dE%40t_%40nFvi%40%7ELfj%40pVcUvo%40sIxu%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=HEES4wLzVLEfEAZGB_RgMPjJoM0=) ### Downtown St. Louis Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800136) ![](https://mediaim.expedia.com/destination/1/55f30f08c9d896777e94f92aa4ffc891.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6058846) ![Clayton map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:sd%7DjFzfnfPgGgNn%40yTzAHpAk%5Bv%40wSkAIAs%40dBg_%40rUxAlBka%40dFb%40RoEtX%7EBbGirAmH%7B%40jFmlAzFh%40tNnFbv%40bI%7BE%7EhAgAp%40%7BC%60f%40%7BJp%7C%40Nr%5BXV%5B%60KkB%60f%40sDfW%7DiBiO%5BlJhEbKqHnG&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=m2Bp6J-dYhmBSGhCVn8k_-PwXiw=) ### Clayton Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6058846) ![Central West End](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199931-Central-West-End.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/544000/544569-saint-louis.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/478000/478477-Saint-Louis.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/479000/479102-Central-West-End.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Central West End](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199935-Central-West-End.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6175135) ![Central West End map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mzzjFlw%7EePsn%40%7BFjE%7Bw%40%60D_z%40xm%40miBj%5BxRrg%40tLlFfi%40KxRn%40lPY%7EDkDfQi%40hKh%40%60JpCfLgElBcNfAky%40eIs%40rFeDdt%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=zQru2uda7HDUx_EHnS_wPOYVPss=) ### Central West End Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6175135) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=7717) ![Creve Coeur map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:y%7C%60kF%60gigPs%40k%40i%40iCeE_CwDeELaGu%40%7DAsAMG%5BeJmDcAwB_%40n%40E%7CCsBk%40a%40wG%7BAKiAcRbAcBjAwLpEuN%7ED_WzKgX%7DDLjBeFwE_DdAoBmD%60B%7CAo%5CwA_HlSrSjGwPmD%7BDdBkI%60AeAdBOXqBxCf%40rKu%7E%40mUrCLeJnTRHk%40eC%40AkFqPJBcOlGCvAiJeFeMoBcPjLgJu%40gCtK_H%40oJqDoK%7BLbGkBgGvKyGeBoFaAoGaBdAu%40qDdC_BTiFgAeDnBoA%7DFeP%7DJ%7EGDog%40u%40Dv%40w%40r%40qHdDAUgD%7E%40mO%7DB%3FRmJs%40A%60%40uIaLoBs%5BUcGj%40Ad%40iBWqLtAlBaf%40bBkVjB_%40zNG%60%7D%40l%40j%40mBphA%5E%5BfbAxsA%7E%40oAltCEbvAjo%40JAfz%40wA%3FKrwA%7BUB%3FfLzUK%40%7EhAmm%40bG%3FeQcYp%40Mp%5B%7DH%40JsNwZ%7D%40cJ_Be%40g%40g%40gDEaG%7D%40gBiJM%3F%60%40kRsCm%40zKoL_B_AnScO%7DBIXXh%40v%40H_%40nCt%40lAm%40Rw%40UDrAdAf%40m%40%7CBo%40mAG%7EDrBj%40FvAzCfDkCvD%7EG%40%3FlAg%40e%40v%40xA%7B%40x%40gAmA%7B%40lA%5BfDx%40%60%40e%40dBl%40rA%3FpA%7DAp%40%7B%40%5Dc%40hCiI%7DCEpAkS%7BI_AxP&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FpMwzKNWNGqj0LaZ4-YUY2d7KHs=) ### Creve Coeur Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=7717) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6295406) ![St. Charles Historic District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:a%7EtkFxplgP%7Bf%40kj%40cy%40wiCbIql%40flCfu%40kt%40llD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kRlGlxr6n0E0b_dVrg0w2HqEMHw=) ### St. Charles Historic District St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Lewis & Clark Boathouse and Nature Center while in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6295406) ## Top Southhampton Hotel Reviews ![Drury Plaza Hotel St. Louis at the Arch](//images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "great location for our trip goals" [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](//images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "Everyone & everything " [](https://expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Forest Park Hotel by MDR](//images.trvl-media.com/lodging/1000000/30000/22300/22298/21d70af8_y.jpg) ### Forest Park Hotel by MDR 10/10 Excellent "Love it " [](https://expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) ![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](//images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel 10/10 Excellent "Beautiful hotel near the Busch stadium- And the Arch no pet fees Great bar and lobby" [](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Was very happy with our stay. Our suite was well worth the very reasonable price. King Bed was very comfortable. AC was a little noisy but no issues." [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Hollywood Casino & Hotel St. Louis](//images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg) ### Hollywood Casino & Hotel St. Louis 10/10 Excellent "Clean room staff very friendly " [](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](//images.trvl-media.com/lodging/1000000/30000/26600/26572/0bb9dbf3_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 10/10 Excellent "clean, well maintained, friendly courteous staff, excellent breakfast" [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Moonrise Hotel](//images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/fe8445aa_y.jpg) ### Moonrise Hotel 10/10 Excellent "Would stay here again, very very very close to the Pageant venue. Free parking behind the hotel was very easy and convenient, pot holes in the parking lot were rough back there." [](https://expedia.co.uk/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![The Cheshire](//images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de_y.jpg) ### The Cheshire 10/10 Excellent "The ambiance and overall experience was superb. A few things could use a spruce-up. (ie. replace the rusty shower curtain rod, perhaps larger bath towels). Otherwise, accommodations were quite satisfactory. The bar tender, Chris, at Fox & Hounds Tavern was spectacular!! All staff were cordial and attentive! We love The Cheshire, and it will remain our destination for our stays in St. Louis! " [](https://expedia.co.uk/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Southhampton. ### How can I save on a Southhampton hotel booking with Expedia? > Members always get our best prices. Find our best Southhampton hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Southhampton hotel? > Hotel prices in Southhampton often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Central West End](https://www.expedia.co.uk/5Star-Central-West-End-St-Louis-Hotels.s50-n6175135-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kirkwood](https://www.expedia.co.uk/5Star-Kirkwood-Hotels.s50-0-d8470.Travel-Guide-Filter-Hotels) - [5 Star Hotels in St. Louis](https://www.expedia.co.uk/5Star-St-Louis-Hotels.s50-0-d178309.Travel-Guide-Filter-Hotels) - [Affton Hotels](https://www.expedia.co.uk/Affton-Hotels.d72322.Travel-Guide-Hotels) - [Hotels near Barnes Jewish Hospital](https://www.expedia.co.uk/Barnes-Jewish-Hospital-Hotels.0-l6160523-0.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Brentwood](https://www.expedia.co.uk/Brentwood-Hotels-Motel-6.0-0-d6123890--bMotel6.Travel-Guide-Filter-Hotels) - [Red Lion Hotels in Brentwood](https://www.expedia.co.uk/Brentwood-Hotels-Red-Lion.0-0-d6123890--bRedLion.Travel-Guide-Filter-Hotels) - [Brentwood Hotels](https://www.expedia.co.uk/Brentwood-Hotels.d6123890.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Central West End](https://www.expedia.co.uk/Central-West-End-St-Louis-Hotels-Pet-Friendly-Hotel.0-n6175135-0-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Central West End Hotels](https://www.expedia.co.uk/Central-West-End-St-Louis-Hotels.0-n6175135-0.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Clayton](https://www.expedia.co.uk/Clayton-St-Louis-Hotels-Hotels-With-Hot-Tubs.0-n6058846-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Clayton Hotels](https://www.expedia.co.uk/Clayton-St-Louis-Hotels.0-n6058846-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Clayton-Tamm](https://www.expedia.co.uk/Clayton-Tamm-St-Louis-Hotels-Gay-Friendly-Hotel.0-n553248635976473263-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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[Car hire near Downtown St. Louis](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-St-Louis.d800136.Car-Hire-Guide) - [Car hire near Gateway Arch](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Gateway-Arch.d502855.Car-Hire-Guide) - [Car hire near St. Louis Union Station](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Louis-Union-Station.d502868.Car-Hire-Guide) - [Car hire near St. Louis](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Louis.d178309.Car-Hire-Guide) - [Car hire in Enterprise Unit 1 Saracen Park Lufton Way](https://www.expedia.co.uk/Enterprise-at-Unit-1-Saracen-Park-Lufton-Way-Yeovil-GBR.v72322.Car-Rental-Guide-Location) - [Fox Rental Cars Rental Cars in Jeff-Vander-Lou](https://www.expedia.co.uk/Fox-Rental-Cars-Car-Rentals-In-Jeff-Vander-Lou.d553248635976470399-c19.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in St. Louis](https://www.expedia.co.uk/Rent-A-Wreck-Car-Rentals-In-St-Louis.d178309-c33.Car-Rental-Guide-Suppliers) - [Green Park Holiday Rentals](https://www.expedia.co.uk/Green-Park-Holiday-Rentals.d6252525.Travel-Guide-HolidayRentals) - [St. Louis Holiday Rentals](https://www.expedia.co.uk/St-Louis-Holiday-Rentals.d178309.Travel-Guide-HolidayRentals) - [Things to do in St. Louis](https://www.expedia.co.uk/Things-To-Do-In-St-Louis.d178309.Travel-Guide-Activities) - [Book Hotels in Southhampton on Expedia.com](https://www.expedia.com/Southhampton-St-Louis-Hotels.0-n553248635975872889-0.Travel-Guide-Filter-Hotels) - Explore a world of travel with Expedia ### Hotels in top St. Louis neighborhoods - [Hotels in Downtown St. Louis](https://expedia.co.uk/Downtown-St-Louis-St-Louis-Hotels.0-n800136-0.Travel-Guide-Filter-Hotels) - [Hotels in Clayton](https://expedia.co.uk/Clayton-St-Louis-Hotels.0-n6058846-0.Travel-Guide-Filter-Hotels) - [Hotels in Central West End](https://expedia.co.uk/Central-West-End-St-Louis-Hotels.0-n6175135-0.Travel-Guide-Filter-Hotels) - [Hotels in Creve Coeur](https://expedia.co.uk/Creve-Coeur-St-Louis-Hotels.0-n7717-0.Travel-Guide-Filter-Hotels) - 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[Hotels in LaSalle Park](https://expedia.co.uk/LaSalle-Park-St-Louis-Hotels.0-n553248635976468715-0.Travel-Guide-Filter-Hotels) - [Hotels in Cahokia](https://expedia.co.uk/Cahokia-East-St-Louis-Hotels.0-n9361-0.Travel-Guide-Filter-Hotels) ### Hotels near popular St. Louis Attractions - [Hotels near Busch Stadium](https://expedia.co.uk/Busch-Stadium-Hotels.0-l502872-0.Travel-Guide-Filter-Hotels) - [Hotels near St. Louis Union Station](https://expedia.co.uk/St-Louis-Union-Station-Hotels.0-l502868-0.Travel-Guide-Filter-Hotels) - [Hotels near Gateway Arch](https://expedia.co.uk/Gateway-Arch-Hotels.0-l502855-0.Travel-Guide-Filter-Hotels) - [Hotels near Washington University in St. Louis](https://expedia.co.uk/Washington-University-In-St-Louis-Hotels.0-l502876-0.Travel-Guide-Filter-Hotels) - [Hotels near St. Louis Zoo](https://expedia.co.uk/St-Louis-Zoo-Hotels.0-l502878-0.Travel-Guide-Filter-Hotels) - [Hotels near Enterprise Center](https://expedia.co.uk/Enterprise-Center-Hotels.0-l502873-0.Travel-Guide-Filter-Hotels) - [Hotels near Dome at America’s Center](https://expedia.co.uk/Dome-At-Americas-Center-Hotels.0-l6058090-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River](https://expedia.co.uk/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Hollywood Casino Amphitheatre](https://expedia.co.uk/Hollywood-Casino-Amphitheatre-Hotels.0-l6174066-0.Travel-Guide-Filter-Hotels) - [Hotels near Barnes Jewish Hospital](https://expedia.co.uk/Barnes-Jewish-Hospital-Hotels.0-l6160523-0.Travel-Guide-Filter-Hotels) ### More accommodation types in Southhampton - [Holiday Homes in St. Louis](https://expedia.co.uk/St-Louis-Private-Holiday-Homes.d178309-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Motels in St. Louis](https://expedia.co.uk/St-Louis-Motels.d178309-aaMotels.Travel-Guide-Accommodation) - [Guest Houses in St. Louis](https://expedia.co.uk/St-Louis-Guest-Houses.d178309-aaGuestHouses.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near Lambert-St. Louis Intl. Airport](https://expedia.co.uk/Lambert-St-Louis-Intl-Airport-Hotels.0-aSTL-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [The Cheshire](https://expedia.co.uk/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) - [Drury Inn & Suites St. Louis Union Station](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) - [Moonrise Hotel](https://expedia.co.uk/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) - [Hollywood Casino & Hotel St. Louis](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) - [Forest Park Hotel by MDR](https://expedia.co.uk/St-Louis-Hotels-Holiday-Inn-St-Louis-Forest-Park.h22298.Hotel-Information) - [Marriott St. Louis Grand](https://expedia.co.uk/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information) - [DoubleTree by Hilton St. Louis Forest Park](https://expedia.co.uk/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) - 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