
Search Hotels in Southhampton, St. Louis
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Southhampton hotels

The Principal Hotel
The Principal Hotel
River City Casino & Hotel
River City Casino & Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
Best Western St. Louis Inn
Best Western St. Louis Inn
Wingate by Wyndham St. Louis Airport
Wingate by Wyndham St. Louis Airport
The Wildwood Hotel
The Wildwood Hotel
Best Western Plus Fenton
Best Western Plus Fenton
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites St. Louis Fairview Heights
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
Pear Tree Inn St. Louis Arnold
Pear Tree Inn St. Louis Arnold
Super 8 by Wyndham Belleville St. Louis Area
Super 8 by Wyndham Belleville St. Louis Area
Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66
Tru By Hilton St. Louis Downtown
Tru By Hilton St. Louis Downtown
Days Inn by Wyndham Collinsville/St. Louis
Days Inn by Wyndham Collinsville/St. Louis
Hyatt Select St. Louis Airport
Hyatt Select St. Louis Airport
Ameristar Casino Resort and Spa
Ameristar Casino Resort and SpaWhere to stay in Southhampton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in St. Louis
- Hotels near Barnes Jewish Hospital
- Barnhart Hotels
- Berger Hotels
- Red Lion Hotels in Brentwood
- Hotels near Busch Stadium
- Central West End Hotels
- Chesterfield Hotels
- Gay-Friendly Hotels in Creve Coeur
- Dardenne Prairie Hotels
- Hotels near Dome at America’s Center
- Hotels near Enterprise Center
- Farmington Hotels
- Hotels near Gateway Arch
- Marriott Hotels & Resorts in Green Park
- Hazelwood Hotels
- Hotels near Hollywood Casino Amphitheatre
- Jonesburg Hotels
- Lithium Hotels
- Mehlville Hotels
- New Offenburg Hotels
- O'fallon Hotels
- Hotels near Old Chain of Rocks Bridge
- Potosi Hotels
- Hotels near River City Casino
- Hotels near Route 66 State Park
- Gay-Friendly Hotels in St. Ann
- St. Charles Hotels
- Best Western St. Louis
- Boyd Gaming Hotels in St. Louis
- Cheap Hotels in St. Louis
- Extended Stay America Suites
- Hotels with Waterslides in St. Louis
- St. Louis Hotels
- Hotels near St. Louis Union Station
- St. Peters Hotels
- Truesdale Hotels
- University City Hotels
- Washington Hotels
- Flights to Kirkwood
- Flights to Lambert-St. Louis Intl.
- Flights to St. Louis
- Flights from Lambert-St. Louis Intl.
- British Airways London (LHR) to St. Louis (STL) flights
- Jetblue Airways New York (JFK) to St. Louis (STL) flights
- Jetblue Airways Boston (BOS) to St. Louis (STL) flights
- Flights from St. Louis
- Flights from Atlanta (ATL) to St. Louis (STL)
- Flights from Austin (AUS) to St. Louis (STL)
- Flights from Birmingham (BHM) to St. Louis (STL)
- Flights from Birmingham (BHX) to St. Louis (STL)
- Flights from Nashville (BNA) to St. Louis (STL)
- Flights from Boston (BOS) to St. Louis (STL)
- Flights from Bristol (BRS) to St. Louis (STL)
- Flights from Baltimore (BWI) to St. Louis (STL)
- Flights from Cincinnati (CVG) to St. Louis (STL)
- Flights from Washington (DCA) to St. Louis (STL)
- Flights from Dallas (DFW) to St. Louis (STL)
- Flights from Dublin (DUB) to St. Louis (STL)
- Flights from Edinburgh (EDI) to St. Louis (STL)
- Flights from East Midlands (EMA) to St. Louis (STL)
- Flights from Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
- Flights from Glasgow (GLA) to St. Louis (STL)
- Flights from Houston (IAH) to St. Louis (STL)
- Flights from New York (JFK) to St. Louis (STL)
- Flights from Las Vegas (LAS) to St. Louis (STL)
- Flights from Los Angeles (LAX) to St. Louis (STL)
- Flights from London (LCY) to St. Louis (STL)
- Flights from New York (LGA) to St. Louis (STL)
- Flights from London (LGW) to St. Louis (STL)
- Flights from London (LHR) to St. Louis (STL)
- Flights from London (LON) to St. Louis (STL)
- Flights from Liverpool (LPL) to St. Louis (STL)
- Flights from Manchester (MAN) to St. Louis (STL)
- Flights from Kansas City (MCI) to St. Louis (STL)
- Flights from Orlando (MCO) to St. Louis (STL)
- Flights from Miami (MIA) to St. Louis (STL)
- Flights from Newcastle (NCL) to St. Louis (STL)
- Flights from Chicago (ORD) to St. Louis (STL)
- Flights from Philadelphia (PHL) to St. Louis (STL)
- Flights from Richmond (RIC) to St. Louis (STL)
- Flights from San Francisco (SFO) to St. Louis (STL)





















































































