Photo by Southernmost Illinois Tourism Bureau
Search Holiday Homes in Southern Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Southern Illinois holiday homes
Brickway Retreat
Brickway RetreatMattoon
9.8 out of 10, Exceptional, (43 reviews)
"Always super clean and inviting!"
Melinda G.
The price is £136
includes taxes & fees
4 Mar - 5 Mar
Vintage Charmer on Main Street
Vintage Charmer on Main StreetGreenup
10.0 out of 10, Exceptional, (61 reviews)
"Host very kind and responsive, nice place to stay."
JEREMY W.
The price is £105
includes taxes & fees
3 Mar - 4 Mar
Du Quoin Fairgrounds
Du Quoin FairgroundsDu Quoin
9.6 out of 10, Exceptional, (15 reviews)
"Overall great place to stay"
Terry Z.
The price is £134
includes taxes & fees
4 Mar - 5 Mar
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shoppingHarrisburg
9.8 out of 10, Exceptional, (25 reviews)
"House was clean and welcoming! Perfect for our short stay!"
Natalie B.
The price is £129
includes taxes & fees
27 Feb - 28 Feb
Park View Place 4 Blocks From the World's Biggest
Park View Place 4 Blocks From the World's BiggestCasey
10.0 out of 10, Exceptional, (40 reviews)
"Wonderful stay and a great location to all we wanted to see and do. Comfortable beds and cute furnishings too!"
Stephanie G.
The price is £162
includes taxes & fees
26 Mar - 27 Mar
Cozy Corner Mascoutah
Cozy Corner MascoutahMascoutah
9.6 out of 10, Exceptional, (76 reviews)
"Great stay! Fantastic host "
Allison D.
The price is £148
includes taxes & fees
23 Mar - 24 Mar
Countryside Private Guest Room
Countryside Private Guest RoomFreeburg
10.0 out of 10, Exceptional, (19 reviews)
"Wonderful property with a wonderful host!"
gerry e.
The price is £71
includes taxes & fees
28 Feb - 1 Mar
Cozy home with the right amenities for your visit to our sweet town.
Cozy home with the right amenities for your visit to our sweet town.Nashville
10.0 out of 10, Exceptional, (22 reviews)
"Wonderful quiet place for some of my family to stay during a family weekend."
Nancy M.
The price is £130
includes taxes & fees
2 Mar - 3 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find holiday rentals that suit your style
Cabins
Aparthotels
Save an average of 15% on thousands of hotels when you're signed in
Top Southern Illinois Hotel Reviews
Comfort Suites Mount Vernon
10/10 Excellent
Find out more about Southern Illinois
Southern Illinois Holiday Homes information
Number of reviews | 628 |
|---|---|
Accommodation | 385 Holiday Homes |
Lowest Price | £71 |
Highest Price | £226 |
Explore a world of travel with Expedia
- Addieville Hotels
- Cabin Rentals in Alto Pass
- B&B in Belknap
- Benton Hotels
- Bluford Hotels
- Caravan Parks in Cairo
- Cabin Rentals in Carlyle
- Centralia Hotels
- Cisne Hotels
- Dix Hotels
- Du Quoin Hotels
- Apartments in Effingham
- B&B in Effingham
- Cabin Rentals in Effingham
- Caravan Parks in Effingham
- Elkville Hotels
- Enfield Hotels
- Ewing Hotels
- Fairfield Hotels
- Flora Hotels
- Holiday Homes in Godfrey
- Herrin Hotels
- Hoyleton Hotels
- Ina Hotels
- Johnston City Hotels
- Kinmundy Hotels
- Macedonia Hotels
- Holiday Homes in Marion
- Mcleansboro Hotels
- Gay-Friendly Hotels in Mount Vernon
- Mount Vernon Hotels
- Nashville Hotels
- Odin Hotels
- Opdyke Hotels
- Holiday Homes in Ozark
- Pinckneyville Hotels
- Rinard Hotels
- Gay-Friendly Hotels in Salem
- Salem Hotels
- Sesser Hotels
- Holiday Homes in Shipman
- Sims Hotels
- B&B in Southeast Illinois
- Caravan Parks in Southwest Illinois
- Pet-Friendly Hotels in Southwest Illinois
- Spa Hotels in Southwest Illinois
- Southwest Illinois Hotels
- Villas in Southwest Illinois
- Motels in Springfield
- Tamaroa Hotels
- Waltonville Hotels
- West City Hotels
- West Frankfort Hotels
- Gay-Friendly Hotels in Whittington
- Pet-Friendly Hotels in Whittington
- Whittington Hotels
- Lodges in Whittington
- Zeigler Hotels
- Flights to Flora
- Flights to Galatia
- Flights to Herrin
- Flights to Mount Vernon
- Flights to Odin
- Flights to Whittington
- Flights from Herrin
- Flights from Mount Vernon
- Flights from Christopher
- Flights from Elkville
- Flights from Kinmundy
- Flights from Opdyke
- Flights from Sims
- Flights from Tamaroa
- Flights from Waltonville
- Flights from Ewing
- Flights from West Frankfort
- Flights from Mill Shoals
- Flights from Walnut Hill
- Flights from Bonnie
- Flights from Dahlgren
- Flights from Macedonia
- Flights from Jeffersonville
- Flights from Jefferson County
- Flights from Benton
- Flights from Du Quoin