Title: TOP Luxury Hotels in Southern Illinois, IL for 2025 - Southern Illinois Upscale Hotels | Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Holiday Rentals in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![Southern Illinois featuring landscape views, a sunset and forest scenes](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau # Find luxury hotels in Southern Illinois, IL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Luxury Hotels Tonight [25 Nov - 26 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-11-25&endDate=2025-11-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-11-26&endDate=2025-11-27&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-11-28&endDate=2025-11-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Southern Illinois Luxury Hotels ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/6781e11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/5a226f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/4ee0764e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1100000/1090700/1090603/fd97bf4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Troy IL/St. Louis Area Troy 8.0/10 Very good (1003) "clean room, gracious and efficient staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine £54 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Super-8-By-Wyndham-Troy-ILSt-Louis-Area.h1090603.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/b9296654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually furnished, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/edd67707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/04574468.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/49800/49709/37dd75af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Effingham North Effingham 7.6/10 Good (1004) "Nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet £50 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Effingham-Hotels-Rodeway-Inn.h49709.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/31e5b1e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/168e329b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/c5f17910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15350000/15340400/15340340/996f936e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suite Dreams Motel By Capital O Mattoon I - 57 Mattoon 7.2/10 Good (533) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £62 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Effingham-Hotels-Suite-Dreams-Hotel.h15340340.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/7d754b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/27748d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/ada044bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, River View | View from room](https://images.trvl-media.com/lodging/2000000/1600000/1599000/1598928/45bd23af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination Metropolis 8.2/10 Very good (1000) "Other than loosing my money it was a nice stay👍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerald £108 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Metropolis-Hotels-Harrahs-Metropolis-Hotel-Casino.h1598928.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/04e0f544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/064919b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/9818af49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861400/861371/264bbe49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt. Vernon IL Mount Vernon 7.8/10 Good (1000) "parking was easy and secure, clean rooms, quiet hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £52 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Super-8-By-Wyndham-Mt-Vernon-IL.h861371.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking (1 King Bed and 1 Queen Bed) | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/a1cede69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/ab1932ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/7a86f04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/902400/902318/53dfd987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Effingham Effingham 6.0/10 (1004) "Staff was helpful. Breakfast was good and they had a variety the room was clean and smoke free" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn C £45 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Effingham-Hotels-Days-Inn-By-Wyndham-Effingham.h902318.Hotel-Information) ![Studio Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/8adbc8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/62f18e1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/0e9cb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/101307ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Carbondale Carbondale 7.4/10 Good (1002) "The hotel was very clean & the breakfast was more than enough " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jill £53 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/c6bf8414.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds (Wet Bar) | Premium bedding, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/f13de7fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/34de46a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1860000/1850700/1850633/154755ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Mattoon by IHG Mattoon 8.2/10 Very good (745) "Great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim £75 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Effingham-Hotels-Holiday-Inn-Express-Suites-Mattoon.h1850633.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/08714d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/98936ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/deca928f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/63665e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Effingham North Effingham 8.4/10 Very good (984) "Very clean room, friendly staff and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Liz £65 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Effingham-Hotels-Quality-Inn-Effingham.h82513.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/ad5778d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10 AM to 10 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/e59929f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/bad6b55f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham O'Fallon O'Fallon 7.2/10 Good (1012) "The staff were very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Delbert £40 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6233859&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6233859) ## Top Southern Illinois Hotel Reviews ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Clean and competitively priced." [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "My room was very clean and the staff was very friendly! They had plenty of breakfast options and I felt safe as a solo traveler here. The price was very reasonable for a great stay!" [](https://expedia.co.uk/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Everything was great! " [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Every clean everyone was so nice and polite will definitely stay again " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](https://images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Clean,nice" [](https://expedia.co.uk/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Baymont by Wyndham O'Fallon St. Louis Area](https://images.trvl-media.com/lodging/1000000/70000/60700/60642/a4ff32db_y.jpg) ### Baymont by Wyndham O'Fallon St. Louis Area 10/10 Excellent "Yes" [](https://expedia.co.uk/Collinsville-Hotels-Baymont-By-Wyndham-OFallon-St-Louis-Area.h60642.Hotel-Information) ## Explore a world of travel with Expedia - 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[Visit McLeansboro](https://www.expedia.co.uk/McLeansboro.dx3000346419) - [Visit Mount Vernon](https://www.expedia.co.uk/Mount-Vernon.dx2463) - [Pheasant Hollow Winery](https://www.expedia.co.uk/Pheasant-Hollow-Winery-Whittington.d6312899.Attraction) - [William Jennings Bryan Boyhood Home and Museum](https://www.expedia.co.uk/William-Jennings-Bryan-Boyhood-Home-And-Museum-Salem.d6187105.Attraction) - [Car hire Whittington](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Whittington.d56062.Car-Hire-Guide) - [People Carrier Car Hire in Flora](https://www.expedia.co.uk/Van-Car-Rentals-In-Flora.d178211-tVan.Car-Rental-Guide-Class) - [Dix Holiday Rentals](https://www.expedia.co.uk/Dix-Holiday-Rentals.d6023670.Travel-Guide-HolidayRentals) - [Enfield Holiday Rentals](https://www.expedia.co.uk/Enfield-Holiday-Rentals.d3000433975.Travel-Guide-HolidayRentals) - [Flora Holiday Rentals](https://www.expedia.co.uk/Flora-Holiday-Rentals.d178211.Travel-Guide-HolidayRentals) - [Nashville Holiday Rentals](https://www.expedia.co.uk/Nashville-Holiday-Rentals.d180762.Travel-Guide-HolidayRentals) - 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