Title: TOP Hotels with Air Conditioning in Southern Illinois, IL for 2026 | Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Holiday Rentals in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![Southern Illinois featuring landscape views, a sunset and forest scenes](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau ![](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Hotels with Air Conditioning Tonight [3 Mar - 4 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-03-03&endDate=2026-03-04&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Mar - 5 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-03-04&endDate=2026-03-05&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-03-06&endDate=2026-03-08&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-03-13&endDate=2026-03-15&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Illinois hotels with air conditioning ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/31850cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/6058a5df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/66dc4e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Mt. Vernon [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) Mount Vernon 9.6/10 Exceptional (1,661 reviews) "Hotel is very clean, nicely furnished and the beds were so comfy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £93 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/8e4b3d15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/47490a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/3a991e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/6cba26b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Effingham [](https://www.expedia.co.uk/Effingham-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Effingham.h50093.Hotel-Information) Effingham 9.2/10 Wonderful (1,005 reviews) "Staff was amazing and the brekfast was good too!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £81 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Effingham-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Effingham.h50093.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/9bba734f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/d9118f52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/86b65f12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/120000/119400/119307/3a194c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western U. S. Inn [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Best-Western-U-S-Inn.h119307.Hotel-Information) Nashville 8.6/10 Excellent (404 reviews) "Good staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose Diego £71 includes taxes & fees 14 Mar - 15 Mar [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Best-Western-U-S-Inn.h119307.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/920000/914400/914400/cb0960c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Desk, soundproofing, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/1000000/920000/914400/914400/69929aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/920000/914400/914400/a72de9ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/920000/914400/914400/cbdc6ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Effingham, IL [](https://www.expedia.co.uk/Effingham-Hotels-Country-Inn-Suites-By-Radisson.h914400.Hotel-Information) Effingham 8.8/10 Excellent (1,001 reviews) "Clean, friendly staff and good breakfast. Location is excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria £66 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Effingham-Hotels-Country-Inn-Suites-By-Radisson.h914400.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/868ce541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/cc771758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/0e3527f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/38f0381c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Effingham [](https://www.expedia.co.uk/Effingham-Hotels-Hampton-Inn-Suites-Effingham.h1321975.Hotel-Information) Effingham 9.6/10 Exceptional (716 reviews) "Very clean, nice hot breakfast, and kind staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin £108 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Effingham-Hotels-Hampton-Inn-Suites-Effingham.h1321975.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/1c773b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/1f46b3f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/2700f966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/8000000/7220000/7214300/7214281/83c59bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Whittington Rend Lake [](https://www.expedia.co.uk/Whittington-Hotels-SureStay-Hotel-By-Best-Western-Whittington-Rend-Lake.h7214281.Hotel-Information) Whittington 8.8/10 Excellent (933 reviews) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £59 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Whittington-Hotels-SureStay-Hotel-By-Best-Western-Whittington-Rend-Lake.h7214281.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11480000/11474500/11474428/16f1378e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/12000000/11480000/11474500/11474428/24e52a5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Premium bedding, down duvets, desk, blackout curtains](https://images.trvl-media.com/lodging/12000000/11480000/11474500/11474428/64c87a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11480000/11474500/11474428/ee5a3a7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Effingham by IHG [](https://www.expedia.co.uk/Effingham-Hotels-Holiday-Inn-Express-And-Suites-Effingham.h11474428.Hotel-Information) Effingham 9.4/10 Exceptional (1,006 reviews) "Room was clean, staff was very pleasant, breakfast was delicious and plentiful and we were able to enjoy all amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £103 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Effingham-Hotels-Holiday-Inn-Express-And-Suites-Effingham.h11474428.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5b15716e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5c7b1e92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b3496784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/6732cce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Mount Vernon [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) Mount Vernon 9.0/10 Wonderful (1,020 reviews) "Very clean and safe stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dale £94 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/0b9bb173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a60abbba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/f5a8458f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Marion [](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) Marion 9.4/10 Exceptional (1,003 reviews) "All of the above, enjoyed the evening meal and breakfast, also staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara £95 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107480000/107471700/107471617/w3840h2557x0y3-d7191bd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/108000000/107480000/107471700/107471617/05056703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/108000000/107480000/107471700/107471617/64b5aed1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/108000000/107480000/107471700/107471617/w3837h2560x3y0-1e0aa062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Effingham [](https://www.expedia.co.uk/Effingham-Hotels-Home2-Suites-By-Hilton-Effingham.h107471617.Hotel-Information) Effingham 9.8/10 Exceptional (39 reviews) "Very kind staff, very clean, very pleased. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin £109 includes taxes & fees 13 Mar - 14 Mar [](https://www.expedia.co.uk/Effingham-Hotels-Home2-Suites-By-Hilton-Effingham.h107471617.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18®ionId=6233859&adults=2&amenities=AIR_CONDITIONING&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6233859) ## Top Southern Illinois Hotel Reviews ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5b15716e_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "I stayed at this property 2 times on a trip to Denver & return. This is a very clean,affordable hotel. Staff was great. Rooms very clean,and quiet. Breakfast was great. I would definitely stay anytime I'm passing through there again." [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Best Western Delta Inn](https://images.trvl-media.com/lodging/1000000/10000/3400/3382/w3840h2556x0y4-dd5ad558_y.jpg) ### Best Western Delta Inn 10/10 Excellent "Friendly staff, clean room!" [](https://expedia.co.uk/Effingham-Hotels-Best-Western-Delta-Inn.h3382.Hotel-Information) ![Baymont by Wyndham Effingham](https://images.trvl-media.com/lodging/1000000/10000/1600/1591/1593eb79_y.jpg) ### Baymont by Wyndham Effingham 10/10 Excellent "Nive toom. Convenient parking " [](https://expedia.co.uk/Effingham-Hotels-Baymont-By-Wyndham-Effingham.h1591.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/91646e6b_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Clean room. Staff was nice. It was inexpensive. Some guests were a bit loud, but you’ll get that with a cheap price. Breakfast was good." [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Holiday Inn Express Metropolis by IHG](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/0b536094_y.jpg) ### Holiday Inn Express Metropolis by IHG 10/10 Excellent "Very pleasant stay!" [](https://expedia.co.uk/Metropolis-Hotels-Holiday-Inn-Express-Metropolis.h211819.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "." [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/2e5b0061_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Clean room, friendly staff, great food. " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "Yes" [](https://expedia.co.uk/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Quality Inn O'Fallon IL - St. Louis](https://images.trvl-media.com/lodging/1000000/70000/64700/64675/0a6ab208_y.jpg) ### Quality Inn O'Fallon IL - St. Louis 10/10 Excellent "Best stuff " [](https://expedia.co.uk/Collinsville-Hotels-Quality-Inn-OFallon-I-64.h64675.Hotel-Information) ## Frequently asked questions ### How much do hotels with air conditioning in Southern Illinois cost? ### What are the best hotels with air conditioning in Southern Illinois? ### How many hotels with air conditioning are there in Southern Illinois? ### What are the best cheap hotels with air conditioning in Southern Illinois? ### What are the top motels with air conditioning in Southern Illinois? ### Are there any family-friendly hotels with air conditioning in Southern Illinois? ### Why book your hotel with air conditioning in Southern Illinois with Expedia? ### How can I find cheap hotels with air conditioning in Southern Illinois? ### What is there to do in Southern Illinois near my hotel with air conditioning? ## Explore a world of travel with Expedia - 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