Search Hotels Suites in Southern Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois Hotels Suites
Tonight
30 Aug - 31 AugTomorrow
31 Aug - 1 SeptNext weekend
4 Sept - 6 SeptIn two weeks
11 Sept - 13 SeptOur top choices for Southern Illinois hotels with suites
£92
includes taxes & fees
6 Sept - 7 Sept
2. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
Abigail
£92
includes taxes & fees
27 Sept - 28 Sept
3. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Fairfield Inn & Suites by Marriott Mt. Vernon Rend LakeMount Vernon
Blake
£87
includes taxes & fees
12 Sept - 13 Sept
£65
includes taxes & fees
31 Aug - 1 Sept
£114
includes taxes & fees
3 Sept - 4 Sept
£61
includes taxes & fees
1 Sept - 2 Sept
7. Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & SuitesCentralia
Corey
£115
includes taxes & fees
3 Sept - 4 Sept
£91
includes taxes & fees
2 Sept - 3 Sept
View all properties
Top Southern Illinois Hotel Reviews
Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"I will return. Management, Dionna, was awesome."
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"Great hotel for a last minute stay."
Frequently asked questions
Explore a world of travel with Expedia
- 4 Star Hotels in Southern Illinois
- 5 Star Hotels in Marissa
- 5 Star Hotels in Southern Illinois
- Notting Hill Cottage
- Buncombe Hotels
- Americas Best Value Inn Marion
- Best Western Marion Hotel
- Betty's Vineyard House
- Downtown Carbondale. Cozy and Cheery Abode
- Hilltop Retreat
- Home2 Suites by Hilton Carbondale
- Oak Grove Cabins
- Playport South camp. Eclipse Hot Spot. South Zone primitive camp sites
- Carbondale Hotels
- Carlyle Hotels
- Americas Best Value Inn Vandalia
- Mariner's Village Resort
- Centralia Hotels
- Baymont by Wyndham Chester IL
- Giant City Lodge
- Restored 1910 Cottage Near Shawnee Forest
- Large Lake front
- Creal Springs Hotels
- Cobblestone Inn & Suites
- Carlton Cabin at Lake of Egypt Hideaway Near Shawnee Forest & lots of wineries
- Castle Cove Lakefront Home
- Log Cabin w/ Clawfoot Tub
- Quality Inn Grayville
- Shawnee Forest In Town Retreat
- Harrisburg Hotels
- Herrin Hotels
- Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
- Kinmundy Hotels
- Gay-Friendly Hotels in Marion
- Treehouse w/ Hot Tub near Shawnee National Forest
- Marion Hotels
- Mcleansboro Hotels
- Quality Inn Mount Vernon
- Odin Hotels
- Pet-Friendly Hotels in Olney
- Rodeway Inn Flora
- Lighthouse Lodge
- Saint Elmo Hotels
- Gay-Friendly Hotels in Salem
- Sports Hotels in Southern Illinois
- Spa Hotels in Southern Illinois
- Pet-Friendly Hotels in Southwest Illinois
- Sparta Hotels
- Waltonville Hotels
- Gay-Friendly Hotels in Whittington
- Pet-Friendly Hotels in Whittington
- Flights to Carbondale
- Flights to Flora
- Flights to Galatia
- Flights to Marion
- Flights to Marissa
- Flights to Mount Vernon
- Flights to Noble
- Flights to Odin
- Flights to Pocahontas
- Flights to Southern Illinois
- Flights from Southern Illinois
- Flights from Vandalia Municipal
- Flights from Makanda
- Flights from Christopher
- Flights from Tamaroa
- Flights from Ava
- Flights from Ewing
- Flights from Marissa
- Flights from Campbell Hill
- Flights from Stonefort
- Flights from Williamson County
- Flights from Boston (BOS) to Carbondale (MDH)
- Flights from London (LON) to Vandalia (VLA)
- Flights from Manchester (MAN) to Vandalia (VLA)
- Flights from Phoenix (PHX) to Vandalia (VLA)