Title: TOP Family-Friendly Hotels in Southern Illinois, IL for 2025 - Southern Illinois Family Welcoming Hotels | Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Holiday Rentals in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![Fort Massac State Park featuring a statue or sculpture, a park and a lake or waterhole](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/208000/208712-Southern-Illinois.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Family-Friendly Hotels in Southern Illinois, IL ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Family-Friendly Hotels Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-10-10&endDate=2025-10-11&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-10-11&endDate=2025-10-12&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=FAMILY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southern Illinois Family-Friendly Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/0640f16c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/f5a8458f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/863f7857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Marion Marion 9.4/10 Exceptional (1004) "We always like staying at this location specially " £59 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/3040b640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/a5bed563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/b6b6aa46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Mt. Vernon Mount Vernon 9.6/10 Exceptional (1477) "Excellent hotel! Clean, excellent breakfast, and friendly staff!" £79 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665176/fe001491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665176/e408085d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665176/ecae6d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665176/47394461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Vandalia by IHG Vandalia 8.8/10 Excellent (745) "Room was very clean and quiet" £81 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Carlyle-Lake-Hotels-Holiday-Inn-Express-Suites-Vandalia.h1665176.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/7ad56ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Queen Beds | Down duvets, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/f3b01060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/cc771758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321975/11916b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Effingham Effingham 9.4/10 Exceptional (646) "Wonderful hotel and very nice staff! " £88 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Effingham-Hotels-Hampton-Inn-Suites-Effingham.h1321975.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/2785ae14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/f0e5a143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/c3df7346.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/b6dd70b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG Murphysboro 9.4/10 Exceptional (485) "Clean room, friendly staff" £93 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/0de8e5ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/2383f778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/93f13efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Sparta by IHG Sparta 9.2/10 Wonderful (353) "Highly recommend this hotel!" £79 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/0b536094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/8f9062f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/9c8c77d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/21f93cd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Metropolis by IHG Metropolis 8.4/10 Very good (1004) "Check in was super easy and the guy working the desk was very friendly and quick. The breakfast was good lots of options. " £76 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Metropolis-Hotels-Holiday-Inn-Express-Metropolis.h211819.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/08714d2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/98936ea6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/deca928f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/90000/82600/82513/c64614a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Effingham North Effingham 8.4/10 Very good (967) "Everything went smoothly and the room was very clean! The staff was very friendly. Highly recommend!" £77 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/Effingham-Hotels-Quality-Inn-Effingham.h82513.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/6cba26b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:00 AM to 11:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/453e2ca5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/8e4b3d15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/60000/50100/50093/25e2a26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Effingham Effingham 9.2/10 Wonderful (1004) "Clean rooms, great staff." £81 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Effingham-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Effingham.h50093.Hotel-Information) ![Luxury Studio, 1 King Bed (202) | Private kitchenette | Mini-fridge, coffee/tea maker, high chair](https://images.trvl-media.com/lodging/22000000/21340000/21331300/21331259/9aefea6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/22000000/21340000/21331300/21331259/a08b1457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Studio, 2 Double Beds (206) | Private kitchenette | Mini-fridge, coffee/tea maker, high chair](https://images.trvl-media.com/lodging/22000000/21340000/21331300/21331259/95fdb65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Studio, 1 Queen Bed (205) | In-room dining](https://images.trvl-media.com/lodging/22000000/21340000/21331300/21331259/5d8df1c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eighteen-Ninety Sleepover Casey 9.6/10 Exceptional (307) "Beds were comfortable. It was within walking distance to everything. Enjoyed a relaxing weekend with a friend. " £99 includes taxes & fees 25 Oct - 26 Oct [](https://www.expedia.co.uk/Effingham-Hotels-Eighteen-Ninety-Sleepover.h21331259.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=6233859&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southern Illinois Hotel Reviews ![Drury Inn & Suites St. Louis O'Fallon, IL](//images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Fast check in. Was a solo female traveler and felt very safe here " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](//images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "The staff is professional and courteous. The room is very clean. The property is well kept. Restaurants are within walking distant. It’s pet friendly." [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Comfort Suites Mount Vernon](//images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Pool open to adults 24 hrs if quiet" [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Best Western Plus Pontoon Beach](//images.trvl-media.com/lodging/3000000/2700000/2695400/2695352/01153352_y.jpg) ### Best Western Plus Pontoon Beach 10/10 Excellent "Very friendly and clean . Very nice place to stay in the area we were !!! " [](https://expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-Pontoon-Beach.h2695352.Hotel-Information) ![Drury Plaza Hotel Mt. Vernon](//images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Check in staff was friendly and prompt. Room is clean and spacious." [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Red Lion Inn & Suites Pontoon Beach](//images.trvl-media.com/lodging/1000000/20000/17400/17338/284b6d11_y.jpg) ### Red Lion Inn & Suites Pontoon Beach 10/10 Excellent "Clean. A little noisy at late hours but not disturbing " [](https://expedia.co.uk/St-Louis-Hotels-Red-Lion-Inn-Suites-Pontoon-Beach.h17338.Hotel-Information) ![Super 8 by Wyndham O'Fallon](//images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg) ### Super 8 by Wyndham O'Fallon 10/10 Excellent "The staff were very nice." [](https://expedia.co.uk/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information) ![Country Inn & Suites by Radisson, Fairview Heights, IL](//images.trvl-media.com/lodging/1000000/20000/19300/19224/54968ac9_y.jpg) ### Country Inn & Suites by Radisson, Fairview Heights, IL 10/10 Excellent "Highly recommended!" [](https://expedia.co.uk/Collinsville-Hotels-Country-Inn-Suites-By-Radisson.h19224.Hotel-Information) ![Radisson Hotel Fairview Heights - St. Louis](//images.trvl-media.com/lodging/1000000/910000/904900/904826/edc9d870_y.jpg) ### Radisson Hotel Fairview Heights - St. Louis 10/10 Excellent "We was very satisfied with the service with the tall young man at the front desk with helping us out." 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[Visit McLeansboro](https://www.expedia.co.uk/McLeansboro.dx3000346419) - [Visit Mount Vernon](https://www.expedia.co.uk/Mount-Vernon.dx2463) - [Pheasant Hollow Winery](https://www.expedia.co.uk/Pheasant-Hollow-Winery-Whittington.d6312899.Attraction) - [William Jennings Bryan Boyhood Home and Museum](https://www.expedia.co.uk/William-Jennings-Bryan-Boyhood-Home-And-Museum-Salem.d6187105.Attraction) - [Car hire Whittington](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Whittington.d56062.Car-Hire-Guide) - [People Carrier Car Hire in Flora](https://www.expedia.co.uk/Van-Car-Rentals-In-Flora.d178211-tVan.Car-Rental-Guide-Class) - [Dix Holiday Rentals](https://www.expedia.co.uk/Dix-Holiday-Rentals.d6023670.Travel-Guide-HolidayRentals) - [Enfield Holiday Rentals](https://www.expedia.co.uk/Enfield-Holiday-Rentals.d3000433975.Travel-Guide-HolidayRentals) - [Flora Holiday Rentals](https://www.expedia.co.uk/Flora-Holiday-Rentals.d178211.Travel-Guide-HolidayRentals) - [Nashville Holiday Rentals](https://www.expedia.co.uk/Nashville-Holiday-Rentals.d180762.Travel-Guide-HolidayRentals) - [Odin Holiday Rentals](https://www.expedia.co.uk/Odin-Holiday-Rentals.d3000346479.Travel-Guide-HolidayRentals) - [Sims Holiday Rentals](https://www.expedia.co.uk/Sims-Holiday-Rentals.d3000346582.Travel-Guide-HolidayRentals) - [Book Family-Friendly Hotels in Southern Illinois on Expedia.com](https://www.expedia.com/Southern-Illinois-Hotels-Family-Hotel.0-0-d6233859-tFamilyHotel.Travel-Guide-Filter-Hotels)