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Check availability on Southern Illinois Business Hotels

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Southern Illinois business-friendly hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

1. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Susan
£94
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel Mt. Vernon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.
A hallway with vending machines and a carpeted floor.

2. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
MARK
£71
includes taxes & fees
15 Oct - 16 Oct
SureStay Hotel by Best Western Whittington Rend Lake
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.

3. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Michael
£94
includes taxes & fees
14 Oct - 15 Oct
Walker's Bluff Casino Resort
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.
A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.
A hotel room with two beds, a large window, and a wall-mounted lamp.
A buffet with labeled food options including turkey sausage and bacon.

4. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
John
£95
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Mount Vernon by IHG
An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.
A hotel room with a desk, two monitors, a keyboard, and a mouse.
A spacious dining area with a long wooden table, multiple chairs, and pendant lighting.
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a television, and a framed artwork on the wall.

5. Best Western Delta Inn

Best Western Delta Inn
Effingham
United States
Susan
£71
includes taxes & fees
25 Oct - 26 Oct
Best Western Delta Inn
A spacious lobby with a patterned carpet, a fireplace, seating area, and a staircase.
A breakfast area with wooden cabinets, a coffee machine, a toaster, and a sign reading "Breakfast Corner".
An indoor swimming pool with clear blue water, surrounded by beige and red tiled flooring, and equipped with multiple ladders and chairs.
A hotel room with two beds, a desk, and a chair.

6. Baymont by Wyndham Marion

Baymont by Wyndham Marion
Marion
United States
Frank
£77
includes taxes & fees
11 Oct - 12 Oct
Baymont by Wyndham Marion
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.
A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.
A parking lot with a Super 8 sign, a white car, and a truck.

7. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
United States
Devin
£57
includes taxes & fees
18 Oct - 19 Oct
Super 8 by Wyndham Mt. Vernon IL
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.
An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.
A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.
A modern living room with a sofa, coffee table, and a dining area with chairs.

8. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
Marion
United States
Lisa
£76
includes taxes & fees
8 Nov - 9 Nov
Country Inn & Suites by Radisson, Marion, IL
A spacious lobby with a reception desk, seating area, and a kitchen in the background.
A hotel room with a bed, bedside table, lamp, desk, chair, and a television.
A golf course with a flagstick, trees, and a water hazard.
A modern kitchen with a central island, bar stools, and various appliances.

9. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
Marion
United States
Michele
£86
includes taxes & fees
8 Nov - 9 Nov
Comfort Inn & Suites Marion I-57
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.
An indoor swimming pool with lounge chairs and a clear view of the pool area.
A hotel room with a large bed, a desk with a chair, a flat-screen TV, a bathtub, and framed pictures on the wall.
A modern kitchen area with a counter, various appliances, and food display items.

10. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Sarah
£100
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Effingham
View all properties

Top Southern Illinois Hotel Reviews

Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Great hotel! Lovely staff, spacious room, and my husband liked the breakfast so much we drove an extra 1.5 hours just to stay there again on our return trip!"
Rachael 1-night trip
Posted 18 hours ago
Holiday Inn Express Metropolis by IHG
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"The front desk staff Kim is very helpful and accommodating, she’s a hard worker too, we had good service from Kim"
Cristino 1-night trip
Posted 2 days ago
Comfort Suites Mount Vernon
Drury Inn & Suites Marion

Drury Inn & Suites Marion

8/10 Good
"friendly and helpful staff. Great food with many options to choose from. Great hot tub"
Carolyn 1-night trip
Posted 3 days ago
Drury Inn & Suites Marion
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Nice location."
James 4-night trip
Posted 4 days ago
Comfort Inn Edwardsville - St. Louis
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

8/10 Good
"Motel is close to the interstate and has a bar and grill next door. Staff was very pleasant and helpful. Lobby and room were clean and neat. The hallway to the room had a musty mildew smell to it. Shower pressure was adequate but weak. TV and Air conditioning were both working well."
Paul 1-night trip
Posted 9 days ago
Quality Inn & Suites Metropolis I-24
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
Lisa 3-night trip
Posted 11 days ago
Country Inn & Suites by Radisson, Marion, IL

Frequently asked questions

How much do business hotels in Southern Illinois cost?
Business hotels in Southern Illinois range between £57 and £100 per night. This means you can lock in a property with conveniences like workspaces and conference rooms at a price that doesn't break the bank. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Southern Illinois?
There are 149 business hotels in Southern Illinois. When work takes you out of town, Expedia makes it easy to find the ideal space with the amenities you need.
Why book your business hotel in Southern Illinois with Expedia?
At Expedia, our business is to help you land a suitable stay at the right price. From 5-star corporate-friendly properties to affordable motor inns filled with all the amenities you need, you'll have your next work trip booked in a few quick clicks.
How can I find cheap business hotels in Southern Illinois?
When you're travelling for work in Southern Illinois, our "business friendly" filter will help you find a suitable hotel. From free WiFi and included breakfast to concierge services and conference spaces, they have the amenities you need to get down to business. You can also narrow your search by your budget and preferred star rating to see the most affordable accommodation.

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