Title: TOP Luxury Hotels in Southeast Ohio, OH for 2025 - Southeast Ohio Upscale Hotels | Expedia.co.uk [Southeast Ohio Travel Guide](https://expedia.co.uk/Southeast-Ohio.dx6059285)[Hotels in Southeast Ohio](https://expedia.co.uk/Southeast-Ohio-Hotels.d6059285.Travel-Guide-Hotels)[Holiday Rentals in Southeast Ohio](https://expedia.co.uk/Southeast-Ohio-Holiday-Rentals.d6059285.Travel-Guide-HolidayRentals)[Flights to Southeast Ohio](https://expedia.co.uk/Cheap-Flights-To-Southeast-Ohio.d6059285.Travel-Guide-Flights)[Southeast Ohio Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Ohio.d6059285.Car-Hire-Guide)[Southeast Ohio Holidays](https://expedia.co.uk/Southeast-Ohio.d6059285.Holidays-City-Breaks) ![Wheeling featuring a city, a suspension bridge or treetop walkway and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/62000/62340-Wheeling.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southeast Ohio, OH ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Ohio Luxury Hotels Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2025-10-11&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Ohio Luxury Hotels ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/35b37036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/w489h735x4y0-922fb495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/bf347d2c_edited_5de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/w493h723x8y0-84b46d0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blennerhassett Hotel Parkersburg 9.4/10 Exceptional (1007) "We enjoyed our stay and will definitely comeback again." £133 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Parkersburg-Hotels-The-Blennerhassett-Hotel.h6032.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/843aa4a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/dc8b2454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/af3d421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/bf3decec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garland Hotel New Concord 9.2/10 Wonderful (891) "Nice hotel " £94 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/New-Concord-Hotels-Garland-Hotel.h13471606.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/c6b09e9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking, Refrigerator & Microwave | Living area | 37-inch plasma TV with satellite channels, TV](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/c5484f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/60c334e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/b78b83f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Adena Inn Chillicothe 7.8/10 Good (752) "Nice easy stay. Fast, friendly check in and location was convenient " £88 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/33bcf957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/51f5c9b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/4ced1260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/256821b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Inn Hebron 6.8/10 (268) "Loved my stay" £38 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Hebron-Hotels-Deluxe-Inn.h18711017.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/699e3988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/fb50516c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/41f3474a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/3780b6ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Granville Inn Granville 9.6/10 Exceptional (716) "Best dinner in town" £185 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Zanesville-Hotels-Granville-Inn.h1868803.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/752fe927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/c13080ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/8fc7374b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/57dcd066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Executive Inn Chillicothe 7.4/10 Good (621) "Clean and comfortable rooms with friendly staff" £52 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Chillicothe-Hotels-Executive-Inn.h13068101.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/4a096f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/6420eb92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/w5500h3649x0y6-0804e267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/e6baab9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ohio University Inn & Conference Center Athens 9.2/10 Wonderful (1004) "Great place to stay while in Athens, OH." £99 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Athens-Hotels-Ohio-University-Inn-Conference-Center.h39931.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/fcc2f5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/7f6bfbd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/201b67ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/dd82e9d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Athens Athens 9.2/10 Wonderful (847) "This hotel was very clean. The guy working the front desk was amazing. The breakfast is a no frills style. " £97 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Athens-Hotels-Hampton-Inn-Athens.h1593237.Hotel-Information) ![Executive Suite, 1 King Bed, Non Smoking, Hot Tub | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/fd9d009f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/3c4f92bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/c44320d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/e7449803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Cambridge Cambridge 8.2/10 Very good (1008) "Great place" £51 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Zanesville-Hotels-Baymont-By-Wyndham-Cambridge.h155861.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/4d0a03ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/c29456d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/36163b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/0412e135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Zanesville City Center Zanesville 7.6/10 Good (259) "Restaurants are near" £70 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Zanesville-Hotels-Zane-Inn-And-Suites.h9003.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=6059285&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Ohio Hotel Reviews ![Christopher Inn and Suites](//images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/50c4cecb_y.jpg) ### Christopher Inn and Suites 10/10 Excellent "Pool and hot tub looked great but didn't have the opportunity to use them" [](https://expedia.co.uk/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Ohio University Inn & Conference Center](//images.trvl-media.com/lodging/1000000/40000/40000/39931/4a096f7d_y.jpg) ### Ohio University Inn & Conference Center 10/10 Excellent "Beautiful hotel, very clean and staff was very friendly!" 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