Title: TOP Business Hotels in Southeast Ohio, OH for 2026 | Expedia.co.uk [Southeast Ohio Travel Guide](https://expedia.co.uk/Southeast-Ohio.dx6059285)[Hotels in Southeast Ohio](https://expedia.co.uk/Southeast-Ohio-Hotels.d6059285.Travel-Guide-Hotels)[Holiday Rentals in Southeast Ohio](https://expedia.co.uk/Southeast-Ohio-Holiday-Rentals.d6059285.Travel-Guide-HolidayRentals)[Flights to Southeast Ohio](https://expedia.co.uk/Cheap-Flights-To-Southeast-Ohio.d6059285.Travel-Guide-Flights)[Southeast Ohio Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southeast-Ohio.d6059285.Car-Hire-Guide)[Southeast Ohio Holidays](https://expedia.co.uk/Southeast-Ohio.d6059285.Holidays-City-Breaks) ![The Upper Falls](https://images.trvl-media.com/place/6140554/71ed754c-3170-47db-be5e-3b5d1faa9c16.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Jake Blucker # Search Business Hotels in Southeast Ohio - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Ohio Business Hotels Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6059285&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southeast Ohio business-friendly hotels ![Front of property](https://images.trvl-media.com/lodging/69000000/68750000/68743000/68742950/de9165e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68750000/68743000/68742950/0a967b7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/69000000/68750000/68743000/68742950/2a4f6883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/69000000/68750000/68743000/68742950/669890c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Hocking College [](https://www.expedia.co.uk/Athens-Hotels-The-Lodge-At-Hocking-College.h68742950.Hotel-Information) Nelsonville 9.0/10 Wonderful (857 reviews) "Great cheap stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £46 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Athens-Hotels-The-Lodge-At-Hocking-College.h68742950.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8900/8811/7e233774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive suite Non smoking, King and Sofa bed, Hot Tub (NO PETS) | In-room safe, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/8900/8811/05439a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Efficiency Suite Nonsmoking, Hot Tub (NO PETS) | In-room safe, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/8900/8811/652b58e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8900/8811/f5aea285.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Zanesville City Center [](https://www.expedia.co.uk/Zanesville-Hotels-Quality-Inn-Suites.h8811.Hotel-Information) Zanesville 8.8/10 Excellent (515 reviews) "Friendly staff. Good breakfast. Older but clean hotel. Great bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £75 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Zanesville-Hotels-Quality-Inn-Suites.h8811.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85100/85068/06cd3a45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/90000/85100/85068/1588cb6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One king study sofabed non smoking | In-room safe, desk, iron/ironing board, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85068/w3839h2559x1y1-bc46d0b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85100/85068/d28d4497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Zanesville [](https://www.expedia.co.uk/Zanesville-Hotels-Hampton-Inn-Zanesville.h85068.Hotel-Information) Zanesville 8.6/10 Excellent (541 reviews) "Had the best time and the staff was so helpful with everything! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Penny £72 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Zanesville-Hotels-Hampton-Inn-Zanesville.h85068.Hotel-Information) ![Indoor pool, open 7 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/3000000/2940000/2936800/2936714/f7412437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2940000/2936800/2936714/9c167101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast ](https://images.trvl-media.com/lodging/3000000/2940000/2936800/2936714/097366e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2940000/2936800/2936714/bcff01c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOLIDAY INN EXPRESS & SUITES ZANESVILLE NORTH by IHG [](https://www.expedia.co.uk/Zanesville-Hotels-Holiday-Inn-Express-Hotel-Suites-Zanesville-North.h2936714.Hotel-Information) Zanesville 9.2/10 Wonderful (570 reviews) "The rooms were very clean and the breakfast was pretty good too. It was my first time having access to a pancake maker." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ALLEN £84 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Zanesville-Hotels-Holiday-Inn-Express-Hotel-Suites-Zanesville-North.h2936714.Hotel-Information) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/430000/421400/421319/9da2d56f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/430000/421400/421319/ed069568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Pool View (Jetted tub) | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/430000/421400/421319/ae6c6470.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421400/421319/2e63bba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Lakewood Inn [](https://www.expedia.co.uk/Hebron-Hotels-Best-Western-Lakewood-Inn.h421319.Hotel-Information) Hebron 8.2/10 Very good (813 reviews) "It was nice and quiet at all time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £90 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Hebron-Hotels-Best-Western-Lakewood-Inn.h421319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/29cf6016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/w489h735x4y0-922fb495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/35b37036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/bf347d2c_edited_5de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blennerhassett Hotel [](https://www.expedia.co.uk/Parkersburg-Hotels-The-Blennerhassett-Hotel.h6032.Hotel-Information) Parkersburg 9.4/10 Exceptional (1,000 reviews) "Very nice hotel, nice big clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cory £124 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Parkersburg-Hotels-The-Blennerhassett-Hotel.h6032.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/6000000/5570000/5567200/5567162/cced036e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/6000000/5570000/5567200/5567162/d975eba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5570000/5567200/5567162/5a1c7d1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/6000000/5570000/5567200/5567162/0fde3316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn St. Clairsville [](https://www.expedia.co.uk/St-Clairsville-Hotels-Comfort-Inn.h5567162.Hotel-Information) St. Clairsville 9.2/10 Wonderful (984 reviews) "Hotel looks brand new" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ann £46 includes taxes & fees 24 Jan - 25 Jan [](https://www.expedia.co.uk/St-Clairsville-Hotels-Comfort-Inn.h5567162.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/1af2e54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/e5a50225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/281a73ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Corporate Suite | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/f7589ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Christopher Inn and Suites [](https://www.expedia.co.uk/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) Chillicothe 9.0/10 Wonderful (1,142 reviews) "Friendly service, clean room, great breakfast, nice area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £106 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15480000/15478800/15478754/a53ca497.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Room, 2 Queen Beds | Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/16000000/15480000/15478800/15478754/1e810393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed (with Sofa Bed) | Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/16000000/15480000/15478800/15478754/68d2b861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/16000000/15480000/15478800/15478754/57f36574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites By Wyndham New Martinsville [](https://www.expedia.co.uk/New-Martinsville-Hotels-Microtel-Inn-Suites-By-Wyndham-New-Martinsville.h15478754.Hotel-Information) New Martinsville 9.2/10 Wonderful (144 reviews) "Great staff. We enjoy staying here They have Thanksgiving Dinner day before Thanksgiving for all. Very friendly . Like family. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank £117 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/New-Martinsville-Hotels-Microtel-Inn-Suites-By-Wyndham-New-Martinsville.h15478754.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/40200/40190/3d41bb25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40190/4316a76e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (Studio) | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/40200/40190/0a3c4369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40200/40190/1123a3a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Lancaster [](https://www.expedia.co.uk/Lancaster-Hotels-Baymont-By-Wyndham-Lancaster.h40190.Hotel-Information) Lancaster 8.4/10 Very good (1,001 reviews) "Room was clean & employees very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathy £72 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Lancaster-Hotels-Baymont-By-Wyndham-Lancaster.h40190.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=6059285&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Ohio Hotel Reviews ![Christopher Inn and Suites](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/50c4cecb_y.jpg) ### Christopher Inn and Suites 10/10 Excellent "We stayed overnight on our way to see family in North Carolina and then on the way back home the following week. The room was very clean, the bed very comfortable, nice amenities, plenty of towels, and quite a nice breakfast with a wide variety of breakfast items to choose from. We would definitely stay again the next time we visit family. " [](https://expedia.co.uk/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ![Ohio University Inn & Conference Center](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/4a096f7d_y.jpg) ### Ohio University Inn & Conference Center 10/10 Excellent "Clean nice looking hotel! " [](https://expedia.co.uk/Athens-Hotels-Ohio-University-Inn-Conference-Center.h39931.Hotel-Information) ![Wingate by Wyndham St. Clairsville/Wheeling](https://images.trvl-media.com/lodging/1000000/30000/25500/25403/44b25798_y.jpg) ### Wingate by Wyndham St. Clairsville/Wheeling 10/10 Excellent "Room was clean and the staff was very friendly " [](https://expedia.co.uk/St-Clairsville-Hotels-Wingate-By-Wyndham-St-ClairsvilleWheeling.h25403.Hotel-Information) ![Country Inn & Suites by Radisson, Pickerington, OH](https://images.trvl-media.com/lodging/1000000/580000/578000/577934/267beb4a_y.jpg) ### Country Inn & Suites by Radisson, Pickerington, OH 10/10 Excellent "Everything turned out very well " [](https://expedia.co.uk/Columbus-Hotels-Executive-Suites-Columbus-East.h577934.Hotel-Information) ![Super 8 by Wyndham Portsmouth](https://images.trvl-media.com/lodging/1000000/40000/39900/39801/2623add7_y.jpg) ### Super 8 by Wyndham Portsmouth 10/10 Excellent "They need to work on improving their key cards because it keeps resetting so you have to visit the front desk to get it working again other than that the stay was comfortable and cozy. " [](https://expedia.co.uk/Portsmouth-Hotels-Super-8-By-Wyndham-Portsmouth.h39801.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Southeast Ohio cost? ### How many business hotels are there in Southeast Ohio? ### Why book your business hotel in Southeast Ohio with Expedia? ### How can I find cheap business hotels in Southeast Ohio? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Adults Only Resorts & in Athens ](https://www.expedia.co.uk/Athens-Hotels-Adults-Only-Resorts.0-0-d6059572-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Athens ](https://www.expedia.co.uk/Athens-Hotels-Gay-Friendly-Hotel.0-0-d6059572-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Canal Winchester ](https://www.expedia.co.uk/Canal-Winchester-Hotels-Gay-Friendly-Hotel.0-0-d181461-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Chillicothe ](https://www.expedia.co.uk/Chillicothe-Hotels-Hotels-With-Indoor-Pools.0-0-d6059576-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - 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