Title: TOP Boutique Hotels in South San Diego, CA for 2025 | Expedia.co.uk [South San Diego Travel Guide](https://expedia.co.uk/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.co.uk/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Holiday Rentals in South San Diego](https://expedia.co.uk/South-San-Diego-Holiday-Rentals.d553248632063518562.Travel-Guide-HolidayRentals)[Flights to South San Diego](https://expedia.co.uk/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.co.uk/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-San-Diego.d553248632063518562.Car-Hire-Guide)[South San Diego Holidays](https://expedia.co.uk/South-San-Diego.d553248632063518562.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/1577a5f9f9b33dbc18377fc367dd66b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in South San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South San Diego Boutique Hotels Tonight [29 Oct - 30 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-29&endDate=2025-10-30&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Oct - 31 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-30&endDate=2025-10-31&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [31 Oct - 2 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South San Diego Boutique Hotels ![Deluxe Room, 1 King Bed | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/2602a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/c9d13d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/cc894470.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 13.49 per person)](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/1303c0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hercor Hotel - Urban Boutique Chula Vista 8.6/10 Excellent (1277) "it was a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven £69 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) ![Junior Suite, 1 King Bed, Ocean View | View from room](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/809d79ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/c1889f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Pacific Sunset) | View from room](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/29e330c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/20000/11600/11528/a8fdbcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pacific Terrace Hotel Pacific Beach 9.6/10 Exceptional (1002) "We loved our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £198 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Pacific-Terrace-Hotel.h11528.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/e9d3f965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/8f9c8a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/29ee9bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/898500/898447/fcaa8786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Republic San Diego, Autograph Collection Downtown San Diego 9.0/10 Wonderful (1146) "Spacious room and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco £152 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Hotel-Republic-San-Diego.h898447.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Fab) | Premium bedding, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/febc9a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego Downtown San Diego 8.4/10 Very good (1400) "Great downtown location. Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hillary [](https://www.expedia.co.uk/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Presidential Suite, 2 Bedrooms, Non Smoking | Living room | 36-inch LCD TV with digital channels, TV, pay films](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/daaed037.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/b76d2e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/12569f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Bay View (Balcony) | Living room | 36-inch LCD TV with digital channels, TV, pay films](https://images.trvl-media.com/lodging/3000000/2140000/2133600/2133509/0ac5494a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alma San Diego Downtown, a Tribute Portfolio Hotel Downtown San Diego 9.0/10 Wonderful (834) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Florinda £125 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Alma-San-Diego-Downtown.h2133509.Hotel-Information) ![SANCTUARY SUITE | View from room](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/5e266fd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Ocean View | 1 bedroom, premium bedding, Tempur-Pedic beds, minibar](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/4a8f0e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, Tempur-Pedic beds, minibar](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/ac8b52b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1220000/1210800/1210726/571d0c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tower23 Hotel Pacific Beach 9.6/10 Exceptional (1001) "Great hotel!!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) RYAN £195 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Tower23-Hotel.h1210726.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/687cbfe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/8c250444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/ef030723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/2000000/1700000/1690300/1690289/3094ddb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pearl Hotel Point Loma 8.6/10 Excellent (1003) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick £117 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-The-Pearl-Hotel.h1690289.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/5000000/4640000/4632300/4632266/0c2dd430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Ocean View | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4640000/4632300/4632266/45d322ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4640000/4632300/4632266/5545e4d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, Multiple Beds, Ocean View | Living area | LCD TV](https://images.trvl-media.com/lodging/5000000/4640000/4632300/4632266/a21ad16d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pantai Inn Village of La Jolla 9.4/10 Exceptional (1000) "Great staff and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean £271 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/La-Jolla-Hotels-Pantai-Inn.h4632266.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/fffb5076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/9cba0c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/28a8b758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2480000/2471900/2471812/08dd481c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo San Diego-Gaslamp Quarter by IHG Downtown San Diego 8.8/10 Excellent (1003) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcos £167 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Hotel-Indigo-Gaslamp-Quarter.h2471812.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2590000/2588900/2588863/6ab1306a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2590000/2588900/2588863/9f52dbaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/3000000/2590000/2588900/2588863/739182a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2590000/2588900/2588863/feb2712f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Scripps Inn La Jolla Cove Village of La Jolla 9.2/10 Wonderful (908) "Beautiful spot to have ocean right out the door. Close to everything and great to have 2 rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) liza [](https://www.expedia.co.uk/La-Jolla-Hotels-Scripps-Inn-La-Jolla-Cove.h2588863.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=553248632063518562&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top South San Diego Hotel Reviews ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Staff is amazing 3 time staying here for a reason really. Great place " [](https://expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Comfortable beds and good sized rooms. Property is outdat" [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Yes" [](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Staff was great. My only two complaint is. The main lobby is over powering with some type of air freshener. And also our balcony door did not lock. It is very noisy at night but you are in down town where all the night life is. It’s a nice stay for sure. " [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "We loved staying here. Charming. Convenient. Clean. Great food at restaurant. Comfy bed. Very happy we chose this place. 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[Things to do in Chula Vista](https://www.expedia.co.uk/Things-To-Do-In-Chula-Vista.d7442.Travel-Guide-Activities) - [Book Boutique Hotels in South San Diego on Expedia.com](https://www.expedia.com/South-San-Diego-Hotels-Boutique-Hotel.0-0-d553248632063518562-tBoutiqueHotel.Travel-Guide-Filter-Hotels)