A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

Search Hotels by Ayres Collection in South San Diego

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
3 Jul - 5 Jul
In two weeks
10 Jul - 12 Jul
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South San Diego Hotel Reviews

Handlery Hotel

Handlery Hotel

10/10 Excellent
"My teen granddaughter & I had a very pleasant stay here. The pool was clean & warm. We enjoyed the 2 tv’s by the pool, we were able to watch the World Cup. The fire pits were nice too & the reef cafe food was incredibly good full of flavor. The location is Hotel circle near most attractions. We can’t wait to come back."
Maria 4-night trip
Posted 4 hours ago
Handlery Hotel

Explore a world of travel with Expedia