Title: Top Guest Houses in South San Diego in 2026 | Expedia.co.uk [South San Diego Travel Guide](https://expedia.co.uk/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.co.uk/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Holiday Rentals in South San Diego](https://expedia.co.uk/South-San-Diego-Holiday-Rentals.d553248632063518562.Travel-Guide-HolidayRentals)[Flights to South San Diego](https://expedia.co.uk/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.co.uk/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-San-Diego.d553248632063518562.Car-Hire-Guide)[South San Diego Holidays](https://expedia.co.uk/South-San-Diego.d553248632063518562.Holidays-City-Breaks) ![Captured this guy doing a wheelie during a beautiful sunset! #imperialbeach #EndlessSummer #autographhotels #Marriott #piersouthresort](https://images.trvl-media.com/place/177683/d4a8a1a3-bd23-4c6a-826e-e0c1c12dddaa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Karen Leone ![](https://images.trvl-media.com/place/177683/d4a8a1a3-bd23-4c6a-826e-e0c1c12dddaa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2026-03-27&endDate=2026-03-29&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [24 Apr - 26 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South San Diego guest houses ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/40601c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/665db20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/a2b981e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1630300/1630286/81c1006b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Primero Hotel [](https://www.expedia.co.uk/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) Downtown Chula Vista 9.2/10 Wonderful (1,000 reviews) "Nice hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £87 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Chula-Vista-Hotels-El-Primero-Hotel.h1630286.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/fa4065fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/a4d923ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/d6f22806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/9000000/8790000/8782500/8782409/cb266ae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Hacienda [](https://www.expedia.co.uk/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) Jamul 9.2/10 Wonderful (547 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christophe £130 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/Spring-Valley-Hotels-Vineyard-Hacienda.h8782409.Hotel-Information) ![Fridge, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/a632fc97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/e8b8e879.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/43d03b41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100230000/100222500/100222473/6043b3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heart of SD | Zoo Nearby | Private Patio | Central [](https://www.expedia.co.uk/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) Mid-City 8.0/10 Very good (4 reviews) "Such a cute and perfect spot! Had all the thoughtful touches. Was very cozy, bed was comfy and little patio was great. I would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanya R. £143 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/San-Diego-Hotels-Modern-Gem-Private-Patio-Central-Heart-Of-SD.h100222473.Hotel-Information) ![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/367769db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/34b1949b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/ea27d1db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69870000/69864700/69864680/5aab7ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hidden King Suite with Garden, Parking - 4 Guest [](https://www.expedia.co.uk/La-Mesa-Hotels-Hidden-King-Suite-With-Garden.h69864680.Hotel-Information) La Mesa 10/10 Exceptional (19 reviews) "Perfect stay. The host was very nice, even checked on me after the first night. Super quiet neighborhood and I will definitely stay here again when I visit back home. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LaShaundra M. £173 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/La-Mesa-Hotels-Hidden-King-Suite-With-Garden.h69864680.Hotel-Information) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/ce0e3d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/33041dfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, cookware/dishes/utensils, dining tables](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/e4a0797d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120450000/120448300/120448291/c396f601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Loft Retreat - North Park SD [](https://www.expedia.co.uk/San-Diego-Hotels-Modern-Loft-Retreat-North-Park-SD.h120448291.Hotel-Information) North Park 10/10 Exceptional (1 review) "Yes!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cecil £229 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/San-Diego-Hotels-Modern-Loft-Retreat-North-Park-SD.h120448291.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/d4d636ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/8b4eb792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/eb794f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118130000/118128600/118128543/0d3d76b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded Garden Cottage Walk to Shops + 55” TV [](https://www.expedia.co.uk/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) University City 10/10 Exceptional (1 review) "Great place,near my son so was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) noel o. £247 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/San-Diego-Hotels-Garden-Cottage-200Mbps-Sofabed-55TV-Patio.h118128543.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/7bcce1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/fbf11521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/15c22d3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/122000000/121930000/121920700/121920680/1293800b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Spacious Full Bed Studio [](https://www.expedia.co.uk/San-Diego-Hotels-Private-Spacious-Full-Bed-Studio.h121920680.Hotel-Information) Mid-City £225 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/San-Diego-Hotels-Private-Spacious-Full-Bed-Studio.h121920680.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-13&endDate=2026-03-14®ionId=553248632063518562&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AA_SPRING_PROMO_553248632063518562) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Guest-Houses.d553248632063518562-aaGuestHouses.Travel-Guide-Accommodation) ## Top South San Diego Hotel Reviews ![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Staff was very friendly and warm. Room was very nice." [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Amazing place , we will come back for sure , Marina view , food , pools , I love everything." [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Paradise Point Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add_y.jpg) ### Paradise Point Resort & Spa 10/10 Excellent "Great family place to stay. " [](https://expedia.co.uk/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![The DEXTRO Little Italy, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/6fe441dd_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Clean room super super comfortable bed! I mean best ever! comfy! location was great! staff was cool!" [](https://expedia.co.uk/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Great location, hospitality " [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "The room was very clean, they had extra shower and hand towels also including pool towels. The staff were very friendly and helpful at the front desk for check-in and check-out. Every time we went to go explore San Diego, we would come back to new bed sheets and a clean room. They do go above and beyond at this location. " [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Embassy Suites by Hilton San Diego Bay Downtown](https://images.trvl-media.com/lodging/1000000/10000/5400/5328/cfe599b5_y.jpg) ### Embassy Suites by Hilton San Diego Bay Downtown 10/10 Excellent "Rooms were clean and spacious. Nearly instant hot water in the shower. :) Definitely use the restaurant/gift shop credit to offset the destination fee. Breakfast and restaurant were great. Evening reception a bit less so food-wise but people enjoyed the free drinks." [](https://expedia.co.uk/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-Bay-Downtown.h5328.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "The room was nice and spacious and clean. Beautiful view!" [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "room was great and Harmony was wonderful" [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ## Find out more about South San Diego ## South San Diego Guest Houses information | Number of reviews | 1,025 | | ----------------- | --------------- | | Accommodation | 15 Guest Houses | | Lowest Price | £87 | | Highest Price | £247 | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Apartments in Asian Pacific Thematic Historic District ](https://www.expedia.co.uk/Asian-Pacific-Thematic-Historic-District-Apartments.d713883578777456640-aaApartments.Travel-Guide-Accommodation) - [B&B in Asian Pacific Thematic Historic District ](https://www.expedia.co.uk/Asian-Pacific-Thematic-Historic-District-Bed-And-Breakfasts.d713883578777456640-aaBedAndBreakfasts.Travel-Guide-Accommodation) - 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