All Hotels by La Quinta Inn & Suites in South Carolina Midlands - 2026 Updated Prices | Expedia

A monument with a statue on top, in front of a large building with columns.

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

26 Oct - 27 Oct

Tomorrow

27 Oct - 28 Oct

This weekend

Next weekend

Our top choices for South Carolina Midlands La Quinta Inn & Suites

A modern kitchen with a long counter, a coffee machine, and a refrigerator.

A modern living room with a flat-screen TV mounted on a textured wall, two sofas with decorative pillows, a patterned rug, and two side tables with plants.

A reception area with a cityscape mural, two reception desks, and a modern design.

A hotel room with two beds, a desk, a chair, and a TV.

1. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Columbia

United States

Lucretia

£75

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a landscaped driveway.

A modern kitchen with a central island, built-in appliances, and a view of the parking lot.

A reception area with a large mural of a bridge over water, a reception desk, and a refrigerator stocked with beverages.

A modern living room with sofas, chairs, a coffee table, and a pool table.

2. La Quinta Inn & Suites by Wyndham Rock Hill

Rock Hill

United States

Thomas

£75

includes taxes & fees

1 Nov - 2 Nov

A panoramic mosaic mural of a cityscape with buildings and greenery.

A modern hotel with a prominent 'La Quinta' sign, large windows, and a covered entrance area.

A neon sign with the text "You're gorgeous Columbia" against a dark wall with vertical lines and horizontal gold bars.

A hotel room with two beds, a nightstand with a phone and lamp, and two large landscape paintings on the wall.

3. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

Columbia

United States

maria

£73

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

A hotel room with a bed, a sofa, a desk, and a TV.

4. La Quinta Inn & Suites by Wyndham Florence

Florence

United States

Brenda

£75

includes taxes & fees

29 Oct - 30 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign up, it's free

Top South Carolina Midlands Hotel Reviews

Hotel Trundle

Hotel Trundle

10/10 Excellent

"This hotel was immaculate! We didn’t even expect the complimentary breakfast or outstanding customer service. Their king sized bed was also the biggest and most comfortable bed I’ve ever slept on. We will be sure to book again in the future!"

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good

"The Staff was Great and helpful. Only thing a little uncomfortable was the water in the sink and shower was barely warm."

Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

10/10 Excellent

"It was a great trip! The staff is always friendly, I stay here on business trips when I am working with the zoo. Great place to stay."

Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

10/10 Excellent

"Everything was fantastic and the gentleman that signed us in was phenomenal and. Courteous."

Hyatt Place Columbia/Harbison

Hyatt Place Columbia/Harbison

10/10 Excellent

"The staff were pleasant, environment was nice and room was clean."

Quality Inn Fort Jackson

Quality Inn Fort Jackson

10/10 Excellent

"Staff was very friendly the breakfast was good the lady that ran the breakfast was really sweet"

Explore a world of travel with Expedia

Book La Quinta Inn & Suites in South Carolina Midlands on Expedia.com