Title: All Hotels by Independent in South Carolina Midlands - 2025 Updated Prices | Expedia.co.uk [South Carolina Midlands Travel Guide](https://expedia.co.uk/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Holiday Rentals in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals)[Flights to South Carolina Midlands](https://expedia.co.uk/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.co.uk/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Carolina-Midlands.d6057938.Car-Hire-Guide)[South Carolina Midlands Holidays](https://expedia.co.uk/South-Carolina-Midlands.d6057938.Holidays-City-Breaks) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Independent in South Carolina Midlands from £45 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-11-26&endDate=2025-11-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-11-27&endDate=2025-11-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South Carolina Midlands Independent Hotels ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/bf604151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/f75cb7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (818) "Awesome hotel stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry £111 includes taxes & fees 12 Dec - 13 Dec [](https://www.expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Fitness facility](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/d9ec3f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Darling Suite | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/84e046fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/8468bfa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/23000000/22220000/22214300/22214254/ec6dc1ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Trundle Downtown Columbia 9.8/10 Exceptional (982) "Enjoyed the stay felt like an event just being there!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £135 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Columbia-Hotels-Hotel-Trundle.h22214254.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/917b8b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/e9758649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/be58ae40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Columbia-Irmo Harbison Irmo 8.6/10 Excellent (323) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ty [](https://www.expedia.co.uk/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/w7294h4496x8y0-e7e0c635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/2b2bb3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/5ac04ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/d6e5ecdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### stayAPT Suites Rock Hill Rock Hill 8.4/10 Very good (195) "Clean and staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cydney [](https://www.expedia.co.uk/Rock-Hill-Hotels-StayAPT-Suites-Rock-Hill.h71945688.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/fed76e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/7dcea9ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/d579010a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/11000000/10940000/10931100/10931075/4f102d5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Carriage House Inn Aiken 9.4/10 Exceptional (460) "Friendly and helpful staff that truly make you feel like a priority. Beautiful historic/boutique hotel in the heart of downtown Aiken. 10/10 will stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evan £169 includes taxes & fees 27 Nov - 28 Nov [](https://www.expedia.co.uk/Aiken-Hotels-Carriage-House-Inn.h10931075.Hotel-Information) ![Comfort Single Room | Desk, free WiFi](https://images.trvl-media.com/lodging/106000000/105700000/105693800/105693778/68f1bad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105700000/105693800/105693778/cd9fd1ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Single Room | Desk, free WiFi](https://images.trvl-media.com/lodging/106000000/105700000/105693800/105693778/c2c5cd7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105700000/105693800/105693778/acdf1d15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orangeburg Inn & Suites Orangeburg 6.2/10 (55) "close to restaurants and shops " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jay [](https://www.expedia.co.uk/Orangeburg-Hotels-Orangeburg-Inn-Suites.h105693778.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/2aa0d516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/8756fe59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/1c7273f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/37047013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florence Inn and Suites Florence 6.4/10 (324) "We had a good experience here. Staff very helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susie £47 includes taxes & fees 27 Nov - 28 Nov [](https://www.expedia.co.uk/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/7895bf64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bf118dbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/cdf5b3db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bca415cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Affordable Suites Florence Florence 9.2/10 Wonderful (120) "Was clean and the staff is friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marilyn [](https://www.expedia.co.uk/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/8025f028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/867ff45e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/8ff91501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101070000/101069700/101069646/bf872483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Regency Inn Rock Hill 7.4/10 Good (125) "I’m very happy to stay at RR" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason £45 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/Rock-Hill-Hotels-Royal-Regency-Inn.h101069646.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/39339da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Regal mid-King Suite | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/ff7460f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/83bdb053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/5a87853c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mantissa Hotel Hartsville 9.2/10 Wonderful (269) "Very nice spacious rooms friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duane £124 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Florence-Hotels-The-Mantissa-Hotel.h15719033.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-10&endDate=2025-12-11®ionId=6057938&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-Independent.0-0-d6057938--bIndependent.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-Carolina-Midlands-Hotels-Independent.0-0-d6057938--bIndependent.Travel-Guide-Filter-Hotels) ## Top South Carolina Midlands Hotel Reviews ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "The room was very clean!" [](https://expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Sabrina was great!" [](https://expedia.co.uk/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Baymont by Wyndham Columbia Fort Jackson](https://images.trvl-media.com/lodging/1000000/580000/574500/574461/c68af965_y.jpg) ### Baymont by Wyndham Columbia Fort Jackson 10/10 Excellent "The rooms were clean, staff was great, they let us stay in our cold room u" [](https://expedia.co.uk/Columbia-Hotels-Baymont-By-Wyndham-Columbia-Fort-Jackson.h574461.Hotel-Information) ![Tru By Hilton Columbia Downtown](https://images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3840h2557x0y3-1e9d91e1_y.jpg) ### Tru By Hilton Columbia Downtown 10/10 Excellent "Paid parking was a surprise" [](https://expedia.co.uk/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Customer service was awesome and the room was clean" [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, SC](https://images.trvl-media.com/lodging/1000000/210000/202900/202867/04e820c9_y.jpg) ### Country Inn & Suites by Radisson, Columbia, SC 10/10 Excellent "Clean room & nice staff " [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h202867.Hotel-Information) ## Explore a world of travel with Expedia - 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[Red Roof Inn Hotels in Upstate South Carolina](https://www.expedia.co.uk/Upstate-South-Carolina-Hotels-Red-Roof-Inn.0-0-d553248635975748552--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Woodfield Hotels](https://www.expedia.co.uk/Woodfield-Hotels.d6348005.Travel-Guide-Hotels) - [Holiday Homes in Woodfield](https://www.expedia.co.uk/Woodfield-Private-Holiday-Homes.d6348005-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Flights to Blythewood](https://www.expedia.co.uk/Cheap-Flights-To-Blythewood.d180657.Travel-Guide-Flights) - [Flights to Columbia](https://www.expedia.co.uk/Cheap-Flights-To-Columbia.d764.Travel-Guide-Flights) - [Flights to South Carolina](https://www.expedia.co.uk/Destinations-In-South-Carolina.d242.Flight-Destinations) - [Flights from South Carolina](https://www.expedia.co.uk/lp/flights/242/flights-from-south-carolina) - [Flights from Elgin](https://www.expedia.co.uk/lp/flights/6051125/flights-from-elgin) - [Flights from Columbia](https://www.expedia.co.uk/lp/flights/764/flights-from-columbia) - 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[Columbia Holiday Rentals](https://www.expedia.co.uk/Columbia-Holiday-Rentals.d764.Travel-Guide-HolidayRentals) - [South Carolina Holiday Rentals](https://www.expedia.co.uk/Destinations-In-South-Carolina.d242.Holiday-Rental-Destinations) - [Elgin Holiday Rentals](https://www.expedia.co.uk/Elgin-Holiday-Rentals.d6051125.Travel-Guide-HolidayRentals) - [Woodfield Holiday Rentals](https://www.expedia.co.uk/Woodfield-Holiday-Rentals.d6348005.Travel-Guide-HolidayRentals) - [Things to do in Columbia](https://www.expedia.co.uk/Things-To-Do-In-Columbia.d764.Travel-Guide-Activities) - [Things to do in South Carolina](https://www.expedia.co.uk/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities) - [Book Independent in South Carolina Midlands on Expedia.com](https://www.expedia.com/South-Carolina-Midlands-Hotels-Independent.0-0-d6057938--bIndependent.Travel-Guide-Filter-Hotels)