Title: TOP Hotels with Early Check-in in South Carolina Midlands, SC for 2026 | Expedia.co.uk [South Carolina Midlands Travel Guide](https://expedia.co.uk/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Holiday Rentals in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals)[Flights to South Carolina Midlands](https://expedia.co.uk/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.co.uk/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Carolina-Midlands.d6057938.Car-Hire-Guide)[South Carolina Midlands Holidays](https://expedia.co.uk/South-Carolina-Midlands.d6057938.Holidays-City-Breaks) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Hotels with Early Check-in Tonight [18 Jan - 19 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Jan - 20 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina Midlands hotels with express check-in ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/320acff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1c5cc7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) Santee 8.0/10 Very good (1,426 reviews) "Always a great stay. Clean room, friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela £62 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/d654e116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/3029fb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) Santee 9.8/10 Exceptional (1,004 reviews) "Clean spacious room, nice amenities and good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna £100 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/99c8fb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/eb4d1288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/f2adc30e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) Orangeburg 9.2/10 Wonderful (1,005 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £95 includes taxes & fees 5 Feb - 6 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/8d8e8f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/32ebf402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/e89adfdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353807/aa69ba2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Aiken South [](https://www.expedia.co.uk/Aiken-Hotels-Country-Inn-Suites-By-Radisson.h1353807.Hotel-Information) Aiken 8.0/10 Very good (1,002 reviews) "Enjoyed my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £71 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Aiken-Hotels-Country-Inn-Suites-By-Radisson.h1353807.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/ae964a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a0deabe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/71b46ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/570000/564000/563976/a9d1fec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) Orangeburg 8.4/10 Very good (711 reviews) "Overall a great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy £70 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/d098e4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/549be75d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/ecf8f7be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/5ae74698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Newberry by IHG [](https://www.expedia.co.uk/Newberry-Hotels-Holiday-Inn-Express-Suites-Newberry.h2803681.Hotel-Information) Newberry 9.0/10 Wonderful (643 reviews) "Yes the young lady that was taking care of the breakfast was super. She did a great job on the food and keeping the place cleaned. Rooms were very clean. Will definitely be staying again in the future. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patsy £101 includes taxes & fees 23 Jan - 24 Jan [](https://www.expedia.co.uk/Newberry-Hotels-Holiday-Inn-Express-Suites-Newberry.h2803681.Hotel-Information) ![Studio, Multiple Beds | Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ea0c2078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.co.uk/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) Florence 9.0/10 Wonderful (733 reviews) "Clean room, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £88 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/68fe8568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/0a76cc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/67e72d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/330000/327100/327027/fac7c96d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Columbia/Harbison [](https://www.expedia.co.uk/Columbia-Hotels-Hyatt-Place-ColumbiaHarbison.h327027.Hotel-Information) Irmo 8.0/10 Very good (1,004 reviews) " Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian £67 includes taxes & fees 6 Feb - 7 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Hyatt-Place-ColumbiaHarbison.h327027.Hotel-Information) ![Outdoor banquet area](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2fa2ba7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2a082860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/1403ad34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29860000/29853300/29853240/2d8379fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza North Augusta by IHG [](https://www.expedia.co.uk/Aiken-Hotels-Crowne-Plaza-North-Augusta.h29853240.Hotel-Information) North Augusta 8.8/10 Excellent (851 reviews) "Great room and great staff. My favorite staycation spot." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cedric £113 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Aiken-Hotels-Crowne-Plaza-North-Augusta.h29853240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/637dd914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/44be5cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/e844503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9860000/9854700/9854604/3941a18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Orangeburg [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Orangeburg 9.4/10 Exceptional (773 reviews) "Clean room, helpful and friendly front desk staff. Tasty breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARK £95 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Orangeburg-Hotels-Hampton-Inn-Suites-Orangeburg.h9854604.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-01&endDate=2026-02-02®ionId=6057938&adults=2&property_amenities_group_explore=express_checkin&sort=RECOMMENDED&openPlayBack=true) ## Top South Carolina Midlands Hotel Reviews ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.co.uk/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - [Spa Hotels in Blythewood ](https://www.expedia.co.uk/Blythewood-Hotels-Spa-Hotels.0-0-d180657-tSpaHotels.Travel-Guide-Filter-Hotels) - [Blythewood Hotels ](https://www.expedia.co.uk/Blythewood-Hotels.d180657.Travel-Guide-Hotels) - [Adults Only Resorts & in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Adults-Only-Resorts.0-0-d764-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Columbia ](https://www.expedia.co.uk/Columbia-Hotels-Budget-Hotels.0-0-d764-tBudgetHotels.Travel-Guide-Filter-Hotels) - 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[Mountain Hotels in South Carolina ](https://www.expedia.co.uk/Destinations-In-South-Carolina-Mountain-Hotel.0-0-d242-tmountainhotel.Hotel-Filter-Destinations) - [Pet-Friendly Hotels in South Carolina ](https://www.expedia.co.uk/Destinations-In-South-Carolina-Pet-Friendly-Hotel.0-0-d242-tPetFriendlyHotel.Hotel-Filter-Destinations) - [Romantic Hotels in South Carolina ](https://www.expedia.co.uk/Destinations-In-South-Carolina-Romantic-Hotel.0-0-d242-tRomanticHotel.Hotel-Filter-Destinations) - [Spa Hotels in South Carolina ](https://www.expedia.co.uk/Destinations-In-South-Carolina-Spa-Hotels.0-0-d242-tSpaHotels.Hotel-Filter-Destinations) - [Winery Hotels in South Carolina ](https://www.expedia.co.uk/Destinations-In-South-Carolina-Winery-Hotels.0-0-d242-tWineryHotels.Hotel-Filter-Destinations) - [South Carolina Hotels ](https://www.expedia.co.uk/Destinations-In-South-Carolina.d242.Hotel-Destinations) - [Earlewood Hotels ](https://www.expedia.co.uk/Earlewood-Columbia-Hotels.0-n6346762-0.Travel-Guide-Filter-Hotels) - 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[Things to do in Columbia ](https://www.expedia.co.uk/Things-To-Do-In-Columbia.d764.Travel-Guide-Activities) - [Things to do in South Carolina ](https://www.expedia.co.uk/Things-To-Do-In-South-Carolina.d242.Travel-Guide-Activities) - [Book Hotels with Early Check-in in South Carolina Midlands on Expedia.com ](https://www.expedia.com/South-Carolina-Midlands-Hotels-Hotel-With-Early-Check-In.0-0-d6057938-thotelwithearlycheckin.Travel-Guide-Filter-Hotels)