Title: TOP Hotels near Museums in South Carolina Midlands, SC for 2026 | Expedia.co.uk [South Carolina Midlands Travel Guide](https://expedia.co.uk/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Holiday Rentals in South Carolina Midlands](https://expedia.co.uk/South-Carolina-Midlands-Holiday-Rentals.d6057938.Travel-Guide-HolidayRentals)[Flights to South Carolina Midlands](https://expedia.co.uk/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.co.uk/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[South Carolina Midlands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-Carolina-Midlands.d6057938.Car-Hire-Guide)[South Carolina Midlands Holidays](https://expedia.co.uk/South-Carolina-Midlands.d6057938.Holidays-City-Breaks) ![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South Carolina Midlands Hotels near Museums Tonight [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Feb - 13 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6057938&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South Carolina Midlands hotels with museums nearby ![Private kitchen](https://images.trvl-media.com/lodging/115000000/114150000/114145000/114144990/w903h683x60y0-af09453c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/115000000/114150000/114145000/114144990/w904h683x60y0-b85a5b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114150000/114145000/114144990/w956h683x33y0-4343721f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/115000000/114150000/114145000/114144990/w904h683x60y0-ac687bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wando Woodlands [](https://www.expedia.co.uk/North-Augusta-Hotels-Wando-Woodlands.h114144990.Hotel-Information) North Augusta £435 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/North-Augusta-Hotels-Wando-Woodlands.h114144990.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=6057938&adults=2&location_highlights_explore=museums&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6057938) ## Top South Carolina Midlands Hotel Reviews ![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg) ### Hilton Garden Inn Columbia/Harbison 10/10 Excellent "Great staff- clean rooms, super location! " [](https://expedia.co.uk/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information) ![Courtyard by Marriott Columbia Downtown at USC](https://images.trvl-media.com/lodging/1000000/10000/2300/2289/w3996h2667x0y0-8dd1e3e0_y.jpg) ### Courtyard by Marriott Columbia Downtown at USC 10/10 Excellent "Yes!" [](https://expedia.co.uk/Columbia-Hotels-Courtyard-By-Marriott-Columbia-Downtown-At-USC.h2289.Hotel-Information) ![Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG](https://images.trvl-media.com/lodging/1000000/690000/688700/688607/805d082b_y.jpg) ### Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG 10/10 Excellent "Latoya at the front desk was very helpful to us with places to eat. She has a very welcoming smile. Very clean rooms and breakfast area. Pat keeps a very clean breakfast area and is very friendly. Breakfast pancakes are a favorite. Adranna check us out when we left and we told her we would be back in march when we go back home to Pennsylvania. She welcomed us to come back soon. If i had employees like these people i would have started my own business. Thank you. Bernard B." [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Suites-Columbia-I-26-Harbison-Blvd.h688607.Hotel-Information) ![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg) ### Sleep Inn Columbia 10/10 Excellent "Clean and friendly staff" [](https://expedia.co.uk/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information) ![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg) ### Graduate by Hilton Columbia SC 10/10 Excellent "Staff were friendly, rooms were clean, pretty easy to get by and lots of stores around. Wished the shower pressure was stronger in the bathroom. Would visit again" [](https://expedia.co.uk/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia at Harbison, SC](https://images.trvl-media.com/lodging/4000000/3540000/3531500/3531475/df25b656_y.jpg) ### Country Inn & Suites by Radisson, Columbia at Harbison, SC 10/10 Excellent "I enjoyed it!! " [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h3531475.Hotel-Information) ![Hyatt Place Columbia/Downtown/The Vista](https://images.trvl-media.com/lodging/9000000/8700000/8690600/8690567/c2bace01_y.jpg) ### Hyatt Place Columbia/Downtown/The Vista 10/10 Excellent "Rooms were clean, staff was great & friendly, breakfast options were plentiful!" [](https://expedia.co.uk/Columbia-Hotels-Hyatt-Place-ColumbiaDowntownThe-Vista.h8690567.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "all of the above" [](https://expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Doubletree by Hilton Columbia, SC](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/db46c2f4_y.jpg) ### Doubletree by Hilton Columbia, SC 10/10 Excellent "Just that the hotel staff were very courteous and provided everything I asked for. 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