Search Adults Only Resorts & Hotels in South Carolina Lowcountry

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on South Carolina Lowcountry Adults Only Resorts & Hotels

This weekend
Next weekend

Our top choices for South Carolina Lowcountry adults-only hotels

Regatta Inn Folly Beach

Regatta Inn Folly Beach
3.5 star property
Folly Beach
9.8 out of 10, Exceptional, (459 reviews)
"Beautiful room, river view, and great breakfast options."
United States
Pam
The price is £193
includes taxes & fees
25 Mar - 26 Mar
Regatta Inn Folly Beach

The Jasmine House

The Jasmine House
4.0 star property
Charleston Historic District
9.4 out of 10, Exceptional, (381 reviews)
"Room was great, staff very friendly and helpful, great breakfast"
United States
Joseph
The price is £449
includes taxes & fees
25 Mar - 26 Mar
The Jasmine House

Eliza Thompson House, Historic Inns of Savannah Collection

Eliza Thompson House, Historic Inns of Savannah Collection
4.0 star property
Historic Downtown Savannah
9.6 out of 10, Exceptional, (1,004 reviews)
"Great place, great location, friendly staff. Syrup h a pleasant stay"
United States
Tony
The price is £242
includes taxes & fees
29 Mar - 30 Mar
Eliza Thompson House, Historic Inns of Savannah Collection

Embassy Suites by Hilton Savannah Airport

Embassy Suites by Hilton Savannah Airport
3.5 star property
Savannah
8.4 out of 10, Very good, (1,004 reviews)
"Great stay"
United States
Annette
The price is £116
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites by Hilton Savannah Airport

Bright Historic Charleston Luxury Condo

Bright Historic Charleston Luxury Condo
Downtown Charleston
9.8 out of 10, Exceptional, (85 reviews)
"Nice property and conveniently located."
United States
Stephen K.
The price is £321
includes taxes & fees
5 Apr - 6 Apr
Bright Historic Charleston Luxury Condo

Water's Edge Inn - Adults Only

Water's Edge Inn - Adults Only
3.5 star property
Folly Beach
9.6 out of 10, Exceptional, (445 reviews)
"Great location, a few blocks from the beach and restaurants/bars. Fantastic breakfast. Really cute rooms with 15’ ceilings and great amenities. "
Canada
Dan
The price is £181
includes taxes & fees
29 Mar - 30 Mar
Water's Edge Inn - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about South Carolina Lowcountry

Discover top South Carolina Lowcountry attractions

The South Carolina Lowcountry is a paradise of experiences that cater to the adventurous spirit of quality-seeking travellers. Start your journey in historic Charleston, where cobblestone streets and antebellum architecture invite you to explore. Visit the iconic Rainbow Row and indulge in gourmet dining at the renowned Husk restaurant, showcasing local ingredients in a rustic setting. For a taste of the natural beauty, venture to the serene landscapes of the ACE Basin, where kayaking among the marshes allows for close encounters with native wildlife, including herons and dolphins. History buffs will appreciate a trip to Fort Sumter, the site where the Civil War ignited, accessible by a scenic ferry ride that offers stunning views of Charleston Harbour. Finally, unwind on the pristine beaches of Hilton Head Island, where you can enjoy cycling along the extensive bike trails or lounging in luxury at beachfront resorts. Staying in the charming area of Beaufort offers a unique experience; this coastal gem is dotted with boutique hotels and offers a laid-back atmosphere, perfect for family adventures or romantic getaways. Here, you can enjoy the rich Gullah culture and explore the picturesque streets filled with art galleries and local shops. Experience the warmth of Southern hospitality while planning your escapades in this captivating region, ensuring you feel pampered at every turn.

Top South Carolina Lowcountry Hotel Reviews

Explore a world of travel with Expedia