Title: The Best Hotels in Serra Mesa, San Diego - 2025 Updated Prices | Expedia.co.uk [Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Serra-Mesa.d553248635953501652.Car-Hire-Guide)[Serra Mesa Holidays](https://expedia.co.uk/Serra-Mesa.d553248635953501652.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Serra Mesa, San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Serra Mesa Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=HOTEL_RESORT) Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=SPA_ON_SITE) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=APART_HOTEL) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=COTTAGE) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=WATER_PARK) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=CONDO) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=OCEAN_VIEW) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=APARTMENT) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=VILLA) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Serra+Mesa%2C+San+Diego%2C+California%2C+United+States+of+America®ionId=553248635953501652&latLong=32.802899%2C-117.138774&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=HOT_TUB) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635953501652&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635953501652&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635953501652&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635953501652&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Serra Mesa, San Diego ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with digital channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/d5ea2f3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside 6.1 mi from Serra Mesa 8.4/10 Very good (5988) "Enjoyed our stay very much." £153 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/23e38216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/7e147d0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/d85ecd0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hard Rock Hotel San Diego Gaslamp Quarter, 6.7 mi from Serra Mesa 9.0/10 Wonderful (2998) "Loved staying here. Will definitely stay again " £189 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/a314a493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/63587042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/881441d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palihotel San Diego Gaslamp Quarter Gaslamp Quarter, 6.3 mi from Serra Mesa 8.8/10 Excellent (1899) "Staff was great location was great" £101 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/43298e98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/f7c3fa7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/289d71c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11600/11553/b435bca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Suites by Wyndham San Diego/Hotel Circle Area 3 mi from Serra Mesa 6.2/10 (1020) "Clean room, friendly staff" £65 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Ramada-Suites-By-Wyndham-San-Diego.h11553.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2d82864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/99024d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/c2540b7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/30000/25900/25840/423e7241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loews Coronado Bay Resort 11.9 mi from Serra Mesa 8.8/10 Excellent (1043) "Beautiful quiet hotel." £199 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Coronado-Hotels-Loews-Coronado-Bay-Resort.h25840.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel 10 mi from Serra Mesa 9.2/10 Wonderful (3317) "Nice place to stay !" £118 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/54935ba5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, City View (1 Queen and 1 Sofabed) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/3de76bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/ddc5f050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/16300/16266/23c18b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gaslamp Plaza Suites Gaslamp Quarter, 6.2 mi from Serra Mesa 8.8/10 Excellent (1010) "Had a great stay " £92 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Gaslamp-Plaza-Suites.h16266.Hotel-Information) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/ce3fee83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/e3d5bf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/93444558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/11100/11026/d9883b91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Horton Grand, Downtown/Gaslamp Quarter 6.5 mi from Serra Mesa 9.0/10 Wonderful (2591) "Great location and friendly staff" £1,073 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Horton-Grand.h11026.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/4877ef6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/1194fa32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/c517acec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11400/11395/3a963240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cordova Hotel on Coronado Island 8.6 mi from Serra Mesa 8.8/10 Excellent (1005) "Cute and unique hotel！" £170 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Coronado-Hotels-El-Cordova-Hotel-On-Coronado-Island.h11395.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/75ec9582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/589f8e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/f8b10da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel 6.2 mi from Serra Mesa 8.4/10 Very good (1607) "I loved the stay here, highly recommended " £106 includes taxes & fees 3 Nov - 4 Nov [](https://www.expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/243b93bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/d154e491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds (Fab) | Premium bedding, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/febc9a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/23900/23816/8f3ed06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bristol Hotel San Diego 6.2 mi from Serra Mesa 8.4/10 Very good (1395) "Very nice staff from check in, clean rooms, quiet and comfortable. " £95 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Bristol-Hotel-San-Diego.h23816.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/8077fd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa 3.5 mi from Serra Mesa 9.2/10 Wonderful (2891) "Great stay overall" £146 includes taxes & fees 24 Oct - 25 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/c491024e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3456147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Kitchenette | Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/eff77449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego Hotel Circle 3.4 mi from Serra Mesa 8.0/10 Very good (2360) "We loved our stay, great price, very clean and excellent location! " £84 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/236157bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/dc860349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/e45ffdb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/8114cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Pensione Hotel Little Italy, 5.8 mi from Serra Mesa 8.6/10 Excellent (1877) "Great place to stay they are right in the middle of everything " [](https://www.expedia.co.uk/San-Diego-Hotels-La-Pensione-Hotel.h914373.Hotel-Information) ![2 outdoor pools, a heated pool, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/01ecd568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/f03b817a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/444d7583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dana on Mission Bay 6.3 mi from Serra Mesa 8.8/10 Excellent (3775) "Great stay" £131 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/c31e05e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/53d75480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/89fdb8c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/12000000/11490000/11486100/11486063/ec632047.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staypineapple, Hotel Z, Gaslamp San Diego Gaslamp Quarter, 6.5 mi from Serra Mesa 9.4/10 Exceptional (1003) "Great staff and clean rooms" £151 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Staypineapple.h11486063.Hotel-Information) ![Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/2b01136a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/325ce31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/1e9b6911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1180000/1176000/1175963/81f394e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham San Diego-East/El Cajon 11 mi from Serra Mesa 7.6/10 Good (1007) "Place was nice and comfy. Decent stay at a very genuine price. " £66 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/El-Cajon-Hotels-Days-Inn-By-Wyndham-San-Diego-EastEl-Cajon.h1175963.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/b510fde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio | Private kitchen | Mini-fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/8de6713f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/1f0a5a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/60000/57300/57248/97d07adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Palmeras Chula Vista 11.5 mi from Serra Mesa 7.0/10 Good (1887) "Quiet area all around nice place to stay !!!" £60 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hotel-Palmeras-Chula-Vista.h57248.Hotel-Information) ![3 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/250333ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sycuan Casino Resort 18.1 mi from Serra Mesa 9.2/10 Wonderful (1565) "Great resort!" £98 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/8104aff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/f52073d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | In-room safe, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/c007c44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kings Inn San Diego 3.7 mi from Serra Mesa 8.8/10 Excellent (3452) "Great place to stay!" £69 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248635953501652&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Serra Mesa Find the best Serra Mesa areas for the activities you enjoy most. - Downtown San Diego - Gaslamp Quarter - Pacific Beach - Mission Beach - Ocean Beach ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476416-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480743-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/476000/476415-Downtown-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=800123) ![Downtown San Diego map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yfwfEzeejUaMaj%40fa%40k%5CbLaPx%40qOkGcWu%40i%5B%60DgKrIcFdRgF%7CrAsAHjJvK%60IqKjOFzR%7EP%7CI%7BH%7CO%7CIfNma%40hn%40%7B%40fIe%5ChZma%40t%40o%40kSei%40E_FfEiEnLwEd%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cs9sAV_TcaQK48f0iT1-t86hPRE=) ### Downtown San Diego Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/475000/475881-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480435-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480422-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480432-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6130021) ![Gaslamp Quarter map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:mmtfEh%7CbjUAwJqIDCm%5B%60x%40OmEpJ%7DPD%40zAiE%40A_B%7BEBFj%5B_HH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=68cMX7ldk9-J6tcepLMBQKKwvpY=) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes rugged coastline, surfing and swimming](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152049-San-Diego.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park featuring a sandy beach and a sunset](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152293-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152300-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Pacific Beach Park which includes drinks or beverages and a beach bar](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152301-Pacific-Beach.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6185751) ![Pacific Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:agfgEvyujUgHcNcG%60IiBwN%7BKtBkf%40inCoKyIyEoFcHy%40aKoT%60mBq_B%7Cl%40aZb%40xB%7DAlAuMdQsExHkAvMbB%7CVpV_F%7CGrk%40tPgDhDlTbMbDlZu%40%60V%7EDxQfMtAlJg%40xH_GxEkRnGkUrA%7DP%60IiFbTv%40lR%60J%7CNcKjBzCfUec%40%60L%7BUxIkP%60IuM%7CH&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5FbBeekgWkepp0jnCE7WEy_Qh88=) ### Pacific Beach Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park featuring street scenes and rides as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22159-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Belmont Park showing a city, rides and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22161-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187064-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park ![Belmont Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/187000/187072-Belmont-Park.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) Photo by Belmont Park [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635998112279) ![Mission Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ec%7DfE%7CgujU_Die%40%7BAYqk%40sBclAvBeNh%40wNtAcg%40%60H_DqUxGwAlD%7EF%60Dm%40v%40%40Bb%40tDIhRqFnGs%40nEBzOdBzF%40xI%7DAvNwH%60BMfBZt%40m%40EhIzJy%40hNJI%7DIrBvAjErA%7EJb%40%7CMcEjJsFzArBfF%7EcA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=hFrZWtAC8u-2IGYk_Bcs7ztzP5Q=) ### Mission Beach If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635998112279) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480252-San-Diego-City.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481012-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481011-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481016-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=177689) ![Ocean Beach map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:eq%7CfEneujUqO%7ByCl%5CdMdL%7B%40pnB%60%60BoUlb%40crB%60I&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=lCc_uj9JIfh1kP738Xl1bJJqo_A=) ### Ocean Beach Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=177689) ## Top Serra Mesa Hotel Reviews ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Excellent rooms, very clean and modern. Well trained staff and good food. This is one of the best hotels near a convention center. Highly recommend it. " [](https://expedia.co.uk/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Nice staff.! " [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Palihotel San Diego Gaslamp Quarter](//images.trvl-media.com/lodging/89000000/88400000/88398500/88398416/4480f6ef_y.jpg) ### Palihotel San Diego Gaslamp Quarter 10/10 Excellent "Staff was great location was great" [](https://expedia.co.uk/San-Diego-Hotels-Palihotel-San-Diego.h88398416.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Very clean, easy to move a lot things to do and Tourist Really love it" [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "Nice stay" [](https://expedia.co.uk/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](//images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "One of the most affordable hotels in this area and its location makes it easy to get around San Diego." [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Loved the location & ease of access to the city." [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "The soap dispenser in the shower was detached from the wall and the AC was blowing a weird smell...like wet clothes." [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Bay Club Hotel & Marina](//images.trvl-media.com/lodging/1000000/10000/2600/2514/8c022c3d_y.jpg) ### Bay Club Hotel & Marina 10/10 Excellent "Beautiful location, close to airport and other activities. Staff was friendly and restaurant was pretty good. Nice to have the option on site. Would definitely stay here again." [](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) ## Frequently asked questions ### What are the best hotels in Serra Mesa that travellers recommend? > [Springhill Suites San Diego Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out as an exceptional choice for travellers, earning an excellent review score of 9.0. This hotel offers spacious suites that provide a comfortable base for your adventures in San Diego. Guests rave about the complimentary breakfast options, which are superb for fueling up before a day of adventure. The outdoor pool and fitness facilities cater to both relaxation and active pursuits, making it an ideal stay for couples and families alike. > > > > Families will find the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information) to be a particularly appealing option, also rated at 9.0. With amenities like a fully-equipped kitchen and an outdoor pool, this hotel makes it easy to enjoy a home-away-from-home experience. The buffet breakfast is a hit among parents and kids, ensuring everyone starts their day on a tasty note. Plus, the nearby rock climbing and mountain biking opportunities add a dash of adventure for the more active families. > > > > For those seeking a vibrant atmosphere, [Town and Country San Diego](https://www.expedia.co.uk/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) offers an engaging experience with a review score of 8.6. This family-friendly resort features a heated pool with a waterslide and playground, making it a fantastic option for those traveling with children. The proximity to local attractions and shopping ensures that both parents and kids will have plenty to do during their stay. > > > > Business travellers will appreciate the [Courtyard by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information), which also holds an 8.6 rating. With a focus on convenience, this hotel offers early check-in options, a business centre, and fitness facilities that cater to professionals on the go. The outdoor pool area provides a refreshing way to unwind after a busy day of meetings, ensuring a balanced stay. > > > > Lastly, for those looking for a blend of comfort and accessibility, the [San Diego Marriott Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information), rated 8.6, provides a welcoming environment. With features such as a rooftop garden and modern meeting facilities, it's well-suited for both leisure and business travellers. The poolside cabanas invite relaxation, while the nearby attractions make it easy to explore the best of San Diego. ### What are the best family hotels in Serra Mesa? > For families seeking a welcoming stay in Serra Mesa, the [Springhill Suites San Diego Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out with its excellent amenities tailored for parents and children alike. With a spacious pool area where the kids can splash around, this hotel also offers connecting rooms and cribs for your little ones, ensuring comfort and convenience during your stay. Guests rave about the complimentary breakfast available on weekdays, a great way to fuel up for a day of adventure. > > > > Another fantastic option is the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information), which boasts similar family-friendly amenities such as connecting rooms and a refreshing pool. The hotel goes the extra mile by providing free meals for children, making dining easier for families. Plus, with amenities like microwaves and dishwashers in the rooms, preparing snacks or meals becomes a breeze. > > > > For a more playful experience, the [Town and Country San Diego](https://www.expedia.co.uk/San-Diego-Hotels-Town-And-Country-San-Diego.h21394.Hotel-Information) is an ideal choice. This vibrant hotel not only has multiple pools for cooling off but also features a playground and fun games designed especially for children. It even offers a waterslide, making it a hit with the younger guests. With connecting rooms and kids' meals available, it's a family paradise. > > > > Lastly, the [San Diego Marriott Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-San-Diego-Marriott-Mission-Valley.h8332.Hotel-Information) is another excellent family-friendly hotel. It provides connecting rooms and a peaceful garden area, superb for some outdoor family time. With its proximity to nearby theme parks, this hotel adds an adventurous touch to your stay, ensuring that the whole family enjoys their vacation. > > > > Each of these hotels has received positive reviews, making them reliable choices for families looking to balance comfort, adventure, and great value on their trip. ### What are the best spa hotels in Serra Mesa? > For a rejuvenating retreat in Serra Mesa, the [WorldMark San Diego - Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-WorldMark-San-Diego-Mission-Valley.h40963.Hotel-Information) is a great choice, receiving a rating of 8.6 from guests. This hotel features accessible spa facilities that make relaxation easy and enjoyable for everyone. With a inviting space and comfortable accommodations, it's an ideal spot for travellers looking to unwind after a day of exploration. > > > > Another option is the [Best Western Seven Seas](https://www.expedia.co.uk/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information), which offers accessible spa amenities as well, rated at 7.8. This hotel combines convenience and comfort, ensuring guests have a pleasant stay while enjoying the soothing spa services available. ### What hotels in Serra Mesa offer free breakfast? > [Springhill Suites San Diego Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) is a fantastic choice for travellers seeking comfort and convenience, especially families. This hotel offers a delightful free continental breakfast, ensuring everyone starts their day off right. With a spacious outdoor pool, it provides a great retreat for kids to splash around while parents unwind. The hotel also features accessible parking and pet-friendly options, suiting a wide range of guests. > > > > Another excellent option is [TownePlace Suites by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information). Here, you can enjoy a complimentary buffet breakfast that will fuel your family's adventures. The outdoor pool is secure and surrounded by sun loungers, making it an inviting space for relaxation. Additionally, the property includes fully-equipped kitchenettes, great for families who prefer to prepare their own meals. > > > > For those traveling without children, the [Homewood Suites by Hilton San Diego Mission Valley/Zoo](https://www.expedia.co.uk/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Mission-ValleyZoo.h13086924.Hotel-Information) offers a more tranquil experience with its premium rooms and a lovely outdoor pool. Couples can enjoy the proximity to local attractions, while still relishing the comforts of home with the in-suite kitchenettes. > > > > Whether you're traveling with family or as a couple, these properties in Serra Mesa provide an array of amenities designed to enhance your stay while ensuring good value for your investment. ### What are the best budget hotels in Serra Mesa? > If you're looking for budget-friendly accommodations in Serra Mesa, the [Springhill Suites San Diego Mission Valley](https://www.expedia.co.uk/San-Diego-Hotels-Springhill-Suites-San-Diego-Mission-Valley.h12881670.Hotel-Information) stands out as a fantastic option. With a guest review rating of 9.0, this hotel features spacious suites that are great for families seeking a comfortable stay. Enjoy a refreshing dip in the outdoor pool or start your day with a complimentary continental breakfast, which is available on weekends too. Families will appreciate the free cribs and the convenient in-room WiFi, making it easy to stay connected while on vacation. > > > > Another excellent choice is the [TownePlace Suites by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-TownePlace-Suites-By-Marriott-San-Diego-Central.h30450040.Hotel-Information), also rated 9.0 by travellers. This hotel has a inviting space with ample amenities, including an outdoor pool, kitchen facilities for easy meal prep, and a grocery shopping service. The complimentary breakfast ensures everyone gets a good start to their day before heading off for family adventures. > > > > For those traveling with children, the [Homewood Suites by Hilton San Diego Mission Valley/Zoo](https://www.expedia.co.uk/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Mission-ValleyZoo.h13086924.Hotel-Information), with a rating of 8.4, is another family-friendly option. This hotel features a kitchenette, making it ideal for families who prefer the convenience of preparing their own meals. Plus, the outdoor pool provides a great spot for kids to splash around after a day of exploring the nearby attractions. > > > > If you're traveling as a couple or looking for a more romantic getaway, consider the [Courtyard by Marriott San Diego Central](https://www.expedia.co.uk/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Central.h854424.Hotel-Information). With a rating of 8.6, this hotel boasts a serene atmosphere, a hot tub for relaxation, and easy access to local attractions, great for couples seeking a blend of comfort and convenience. > > > > In summary, whether you're traveling with kids or looking for a peaceful retreat, Serra Mesa offers budget-friendly options that cater to a variety of needs and preferences. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Serra Mesa hotel for you. ### How can I save on a Serra Mesa hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Serra Mesa hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Serra Mesa hotel? > Hotel prices in Serra Mesa often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. 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[Flights from Spokane (SFF) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sff/myf/spokane-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sfo/myf/san-francisco-to-san-diego) - [Flights from Salt Lake City (SLC) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/slc/myf/salt-lake-city-to-san-diego) - [Flights from Saranac Lake (SLK) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/slk/myf/saranac-lake-to-san-diego) - [Flights from Sacramento (SMF) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/smf/myf/sacramento-to-san-diego) - [Flights from Sydney (SYD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/syd/myf/sydney-to-san-diego) - [Flights from Santa Paula (SZP) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/szp/myf/santa-paula-to-san-diego) - [Flights from Tacoma (TIW) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/tiw/myf/tacoma-to-san-diego) - [Flights from Thermal (TRM) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/trm/myf/thermal-to-san-diego) - [Flights from Troutdale (TTD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ttd/myf/troutdale-to-san-diego) - [Flights from Concord (USA) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/usa/myf/concord-to-san-diego) - [Flights from Québec (YQB) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yqb/myf/quebec-to-san-diego) - [Flights from Yuma (YUM) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yum/myf/yuma-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yvr/myf/vancouver-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yyz/myf/toronto-to-san-diego) - [Visit Central San Diego](https://www.expedia.co.uk/Central-San-Diego.dx6056570) - [Visit Birdland](https://www.expedia.co.uk/San-Diego-Birdland.dx553248635976479135) - [Visit Clairemont](https://www.expedia.co.uk/San-Diego-Clairemont.dx177692) - [Car hire near Kearny Mesa](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kearny-Mesa.d3000663380.Car-Hire-Guide) - [Central San Diego Holiday Rentals](https://www.expedia.co.uk/Central-San-Diego-Holiday-Rentals.d6056570.Travel-Guide-HolidayRentals) - [Book Hotels in Serra Mesa on Expedia.com](https://www.expedia.com/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels) - Explore a world of travel with Expedia ### Hotels in top San Diego neighborhoods - [Hotels in Downtown San Diego](https://expedia.co.uk/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Hotels in Gaslamp Quarter](https://expedia.co.uk/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Hotels in Pacific Beach](https://expedia.co.uk/Pacific-Beach-San-Diego-Hotels.0-n6185751-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Beach](https://expedia.co.uk/Mission-Beach-San-Diego-Hotels.0-n553248635998112279-0.Travel-Guide-Filter-Hotels) - [Hotels in Ocean Beach](https://expedia.co.uk/Ocean-Beach-San-Diego-Hotels.0-n177689-0.Travel-Guide-Filter-Hotels) - [Hotels in Point Loma](https://expedia.co.uk/Point-Loma-San-Diego-Hotels.0-n6171538-0.Travel-Guide-Filter-Hotels) - [Hotels in Mission Valley](https://expedia.co.uk/Mission-Valley-San-Diego-Hotels.0-n800124-0.Travel-Guide-Filter-Hotels) - [Hotels in Old Town San Diego](https://expedia.co.uk/Old-Town-San-Diego-San-Diego-Hotels.0-n6347116-0.Travel-Guide-Filter-Hotels) - [Hotels in Little Italy](https://expedia.co.uk/Little-Italy-San-Diego-Hotels.0-n6161280-0.Travel-Guide-Filter-Hotels) - [Hotels in North Pacific Beach](https://expedia.co.uk/North-Pacific-Beach-San-Diego-Hotels.0-n553248635976383450-0.Travel-Guide-Filter-Hotels) - [Hotels in Crown Point](https://expedia.co.uk/Crown-Point-San-Diego-Hotels.0-n553248635976468673-0.Travel-Guide-Filter-Hotels) - [Hotels in North Park](https://expedia.co.uk/North-Park-San-Diego-Hotels.0-n6346499-0.Travel-Guide-Filter-Hotels) - [Hotels in Carmel Valley](https://expedia.co.uk/Carmel-Valley-San-Diego-Hotels.0-n553248633938969513-0.Travel-Guide-Filter-Hotels) - [Hotels in Hillcrest](https://expedia.co.uk/Hillcrest-San-Diego-Hotels.0-n6191797-0.Travel-Guide-Filter-Hotels) - [Hotels in La Playa](https://expedia.co.uk/La-Playa-San-Diego-Hotels.0-n553248635976481835-0.Travel-Guide-Filter-Hotels) - [Hotels in Point Loma Heights](https://expedia.co.uk/Point-Loma-Heights-San-Diego-Hotels.0-n553248632557191746-0.Travel-Guide-Filter-Hotels) - [Hotels in East Village](https://expedia.co.uk/East-Village-San-Diego-Hotels.0-n553248633849130034-0.Travel-Guide-Filter-Hotels) - [Hotels in University City](https://expedia.co.uk/University-City-San-Diego-Hotels.0-n553248635976008131-0.Travel-Guide-Filter-Hotels) - [Hotels in Torrey Pines](https://expedia.co.uk/Torrey-Pines-La-Jolla-Hotels.0-n553248632557170134-0.Travel-Guide-Filter-Hotels) - [Hotels in Marina District](https://expedia.co.uk/Marina-District-San-Diego-Hotels.0-n3000663388-0.Travel-Guide-Filter-Hotels) ### Hotels near popular San Diego Attractions - [Hotels near Stadium Golf Center & Batting Cages](https://expedia.co.uk/Stadium-Golf-Center-Batting-Cages-Hotels.0-l553248621555611799-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego Zoo](https://expedia.co.uk/San-Diego-Zoo-Hotels.0-l502547-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego Convention Center](https://expedia.co.uk/San-Diego-Convention-Center-Hotels.0-l6125294-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Bay](https://expedia.co.uk/Mission-Bay-Hotels.0-l6185904-0.Travel-Guide-Filter-Hotels) - [Hotels near San Ysidro Border Crossing](https://expedia.co.uk/San-Ysidro-Border-Crossing-Hotels.0-l553248621551385128-0.Travel-Guide-Filter-Hotels) - [Hotels near Mission Beach](https://expedia.co.uk/Mission-Beach-Hotels.0-l506109-0.Travel-Guide-Filter-Hotels) - [Hotels near Balboa Park](https://expedia.co.uk/Balboa-Park-Hotels.0-l507458-0.Travel-Guide-Filter-Hotels) - [Hotels near San Diego State University](https://expedia.co.uk/San-Diego-State-University-Hotels.0-l502542-0.Travel-Guide-Filter-Hotels) - [Hotels near Hotel Circle](https://expedia.co.uk/Hotel-Circle-Hotels.0-l6270979-0.Travel-Guide-Filter-Hotels) - [Hotels near Naval Base San Diego](https://expedia.co.uk/Naval-Base-San-Diego-Hotels.0-l553248635941372147-0.Travel-Guide-Filter-Hotels) ### More accommodation types in Serra Mesa - [Holiday Homes in San Diego](https://expedia.co.uk/San-Diego-Private-Holiday-Homes.d3073-aaPrivateHolidayHomes.Travel-Guide-Accommodation) - [Apartments in San Diego](https://expedia.co.uk/San-Diego-Apartments.d3073-aaApartments.Travel-Guide-Accommodation) - [Cottages in San Diego](https://expedia.co.uk/San-Diego-Cottages.d3073-aaCottages.Travel-Guide-Accommodation) - [Guest Houses in San Diego](https://expedia.co.uk/San-Diego-Guest-Houses.d3073-aaGuestHouses.Travel-Guide-Accommodation) - [Villas in San Diego](https://expedia.co.uk/San-Diego-Villas.d3073-aaVillas.Travel-Guide-Accommodation) - [Serviced Apartments in San Diego](https://expedia.co.uk/San-Diego-Apart-Hotels.d3073-aaApartHotels.Travel-Guide-Accommodation) - [Resorts in San Diego](https://expedia.co.uk/San-Diego-Hotel-Resorts.d3073-aaHotelResorts.Travel-Guide-Accommodation) - [Motels in San Diego](https://expedia.co.uk/San-Diego-Motels.d3073-aaMotels.Travel-Guide-Accommodation) - [Hostels in San Diego](https://expedia.co.uk/San-Diego-Hostels.d3073-aaHostels.Travel-Guide-Accommodation) - [Houseboats in San Diego](https://expedia.co.uk/San-Diego-Houseboats.d3073-aaHouseboats.Travel-Guide-Accommodation) - [Caravan Parks in San Diego](https://expedia.co.uk/San-Diego-Caravan-Parks.d3073-aaCaravanParks.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near San Diego Intl. Airport](https://expedia.co.uk/San-Diego-Intl-Airport-Hotels.0-aSAN-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field Airport](https://expedia.co.uk/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Hotels near Brown Field Municipal Airport](https://expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Hotels near McClellan-Palomar Airport](https://expedia.co.uk/McClellan-Palomar-Airport-Hotels.0-aCLD-0.Travel-Guide-Filter-Hotels) - [Hotels near Oceanside Airport](https://expedia.co.uk/Oceanside-Airport-Hotels.0-aOCN-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Days Inn by Wyndham San Diego Hotel Circle](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) - [Hotel del Coronado, Curio Collection by Hilton](https://expedia.co.uk/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) - [San Diego Marriott La Jolla](https://expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) - [The Dana on Mission Bay](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) - [The Sofia Hotel](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) - [Bay Club Hotel & Marina](https://expedia.co.uk/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information) - [Legacy Resort Hotel & Spa](https://expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) - [Wyndham Garden San Diego Near SeaWorld](https://expedia.co.uk/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) - [California Suites Hotel](https://expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) - [The Little Italy Hotel Downtown San Diego](https://expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) - [Kings Inn San Diego](https://expedia.co.uk/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) - [Sheraton San Diego Resort](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) [See a list of all hotels in San Diego](https://expedia.co.uk/All-San-Diego-Hotels.d3073.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Serra Mesa on Expedia.com](https://www.expedia.com/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Echo Park](https://expedia.co.uk/Echo-Park-Los-Angeles-Hotels.0-n799568389158125568-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Montecito](https://expedia.co.uk/5Star-Montecito-Santa-Barbara-Hotels.s50-n6055656-0.Travel-Guide-Filter-Hotels) - [Hotels in Downtown San Diego](https://expedia.co.uk/Downtown-San-Diego-San-Diego-Hotels.0-n800123-0.Travel-Guide-Filter-Hotels) - [Hotels in Gaslamp Quarter](https://expedia.co.uk/Gaslamp-Quarter-San-Diego-Hotels.0-n6130021-0.Travel-Guide-Filter-Hotels) - [Hotels in Union Square](https://expedia.co.uk/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels) - [Fisherman's Wharf Hotels with Pool](https://expedia.co.uk/Fishermans-Wharf-San-Francisco-Hotels-Hotels-With-Pool.0-n800128-0-tHotelswithPool.Travel-Guide-Filter-Hotels) - [Hotels in Downtown Los Angeles](https://expedia.co.uk/Downtown-Los-Angeles-Los-Angeles-Hotels.0-n800058-0.Travel-Guide-Filter-Hotels) - [Hotels in Hollywood](https://expedia.co.uk/Hollywood-Los-Angeles-Hotels.0-n8365-0.Travel-Guide-Filter-Hotels) - [Hotels in Russian Hill](https://expedia.co.uk/Russian-Hill-San-Francisco-Hotels.0-n553248621561137041-0.Travel-Guide-Filter-Hotels) - [Hotels in Castro District](https://expedia.co.uk/Castro-District-San-Francisco-Hotels.0-n179363-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Hollywood](https://expedia.co.uk/5Star-Hollywood-Los-Angeles-Hotels.s50-n8365-0.Travel-Guide-Filter-Hotels) - [Hotels in Fisherman's Wharf](https://expedia.co.uk/Fishermans-Wharf-San-Francisco-Hotels.0-n800128-0.Travel-Guide-Filter-Hotels) Cars - [Car rental in Downtown Los Angeles](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-Los-Angeles.d800058.Car-Hire-Guide) - [Car rental in Downtown San Francisco](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-San-Francisco.d6151902.Car-Hire-Guide) - [Car rental in Fisherman's Wharf](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Fishermans-Wharf.d800128.Car-Hire-Guide) - [Car rental in Union Square](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Union-Square.d800129.Car-Hire-Guide) Packages - [Downtown Los Angeles Holidays](https://expedia.co.uk/Downtown-Los-Angeles.d800058.Holidays-City-Breaks) - [Hollywood Holidays](https://expedia.co.uk/Hollywood.d8365.Holidays-City-Breaks) General - [Visit Fisherman's Wharf](https://expedia.co.uk/San-Francisco-Fishermans-Wharf.dx800128) - [Visit Hollywood Hills](https://expedia.co.uk/Los-Angeles-Hollywood-Hills.dx553248635074843803) - [Visit Downtown Los Angeles](https://expedia.co.uk/Los-Angeles-Downtown-Los-Angeles.dx800058) - [Visit Union Square](https://expedia.co.uk/San-Francisco-Union-Square.dx800129) - [Visit Skid Row](https://expedia.co.uk/Los-Angeles-Skid-Row.dx553248635976007248) - [Visit Silver Lake](https://expedia.co.uk/Los-Angeles-Silver-Lake.dx3000663210) - [Visit Nob Hill](https://expedia.co.uk/San-Francisco-Nob-Hill.dx138629) - [Visit Ocean Beach](https://expedia.co.uk/San-Diego-Ocean-Beach.dx177689) - [Visit Hollywood](https://expedia.co.uk/Los-Angeles-Hollywood.dx8365) - [Visit Downtown San Diego](https://expedia.co.uk/San-Diego-Downtown-San-Diego.dx800123) - [Visit Newbury Park](https://expedia.co.uk/Los-Angeles-Newbury-Park.dx602883) - [Visit Downtown San Francisco](https://expedia.co.uk/San-Francisco-Downtown-San-Francisco.dx6151902)