Serra Mesa Holidays

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Your Serra Mesa Holiday

Make planning your travels easier by snapping up a holiday package to Serra Mesa. Let us handle all the details, so you can concentrate on savouring everything this neighbourhood has to offer. Begin your trip to Serra Mesa by visiting nearby attractions such as Snapdragon Stadium, Fashion Valley Mall and Mission Valley Mall. Stop daydreaming and start doing. When you're ready to book your dream holiday to Serra Mesa, Expedia will help you get there.

Price found within the past 48 hours. Click for updated prices.
  • 8 outdoor pools, open 9:00 AM to 9:00 PM, pool cabanas (surcharge)
    Jul 1 - Jul 14

    Hyatt Vacation Club at The Welk, San Diego Area + Flight

    Lawrence Welk Resort Village
    13 nights
    3.5 star property
    8.4/10 - Very good (1,828 reviews)
    "The accommodations are impeccably maintained and offer a wide array of recreational facilities for children. The unit itself is generously proportioned, and the bedding is of exceptional quality."
    Reviewed May 17, 2026
    Return • Birmingham (BHX) - Los Angeles (LAX)
    BHX - LAX • 1 stop LAX - BHX • 1 stop
    Save 100% on your flight
    £2,671
    £1,649
    per traveller
    found 1 day ago
    Hyatt Vacation Club at The Welk, San Diego Area
  • Exterior
    Jul 1 - Jul 14

    The Sofia Hotel + Flight

    Downtown San Diego
    13 nights
    3.5 star property
    8.6/10 - Excellent (2,062 reviews)
    "beautiful rooms and great location."
    Reviewed May 19, 2026
    Return • Birmingham (BHX) - Los Angeles (LAX)
    BHX - LAX • 1 stop LAX - BHX • 1 stop
    Save 100% on your flight
    £3,417
    £1,832
    per traveller
    found 1 day ago
    The Sofia Hotel
  • Classic Studio | In-room dining
    Jul 21 - Aug 4

    The Artifact Inn + Flight

    Downtown San Diego
    14 nights
    2.0 star property
    9.2/10 - Wonderful (76 reviews)
    "Clean rooms and close to downtown. I highly recommend this place to anyone. It was amazing. Will definitely be back. "
    Reviewed April 30, 2026
    Return • Manchester (MAN) - San Diego (SAN)
    MAN - SAN • 1 stop SAN - MAN • 1 stop
    Save 100% on your flight
    £7,196
    £4,261
    per traveller
    found 1 day ago
    The Artifact Inn
  • Lobby
    Jul 10 - Jul 17

    Margaritaville Hotel San Diego Gaslamp Quarter + Flight

    Downtown San Diego
    7 nights
    4.0 star property
    9.0/10 - Wonderful (1,358 reviews)
    "Clean room"
    Reviewed May 18, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • 1 stop SAN - LHR • 1 stop
    Save 100% on your flight
    £2,956
    £2,028
    per traveller
    found 1 day ago
    Margaritaville Hotel San Diego Gaslamp Quarter
  • Standard Single Room, Oceanfront | View from room
    Jul 10 - Jul 17

    Ocean Park Inn + Flight

    Pacific Beach
    7 nights
    3.0 star property
    9.4/10 - Exceptional (1,010 reviews)
    "Perfect stay right by the sand. We didn’t realize we booked the weekend of SDSU graduation so we were worried about the noise/crowds. I can say that we had no reason to worry! Couldn’t hear anything from our room and never felt too crowded. We were able to borrow chairs and boogie boards and had a fantastic time on the beach. The room was super clean and staff was lovely. Breakfast was great too. We can’t wait to come back!"
    Reviewed May 18, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • 1 stop SAN - LHR • 1 stop
    Save 100% on your flight
    £2,638
    £1,838
    per traveller
    found 1 day ago
    Ocean Park Inn

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
Downtown San Diego

Downtown San Diego

4 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Serra Mesa

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
The price is £124 per night from 27 May to 28 May
£124
27 May - 28 May
includes taxes & fees
8.6/10 Excellent! (2,062 reviews)
"beautiful rooms and great location."

Reviewed on 19 May 2026

The Sofia Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is £226 per night from 25 May to 26 May
£226
25 May - 26 May
includes taxes & fees
8.8/10 Excellent! (2,598 reviews)
"While the property was beautiful, well maintained, and the staff mostly pleasant, the prices were outrageous. $30 for a mediocre buger at best, and drinks were around $20. Who knows if they actually put liquor in your cocktail because they made them where you couldn't see them. Its almost as if they ..."

Reviewed on 19 May 2026

Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
The price is £227 per night from 25 May to 26 May
£227
25 May - 26 May
includes taxes & fees
9/10 Wonderful! (2,837 reviews)
"Amazing property. A must visit for San Diego"

Reviewed on 18 May 2026

Manchester Grand Hyatt San Diego
See all 9,147 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Serra Mesa travel package cost?
Explore the best of Serra Mesa from as low as . Choose from a great selection of flights, hotels and rental cars to suit every budget. You can pick up even better deals when you add a few sightseeing tours to your travel package.
If I'm not able to travel, can I cancel my Serra Mesa travel package?
Whether it's your hotel or flight, yes, you can cancel or amend it. Booked your Serra Mesa travel package in the last 24 hours? You may be able to make changes for free. For bookings made more than 24 hours ago, you may incur a charge from your airline, hotel or car rental company. For more information, check out our Customer Service Portal. We're here to help you every step of the way.
How do I get a cheap travel package to Serra Mesa?
Combining your hotel and flight with Expedia won't just save you time — it'll save you cash too. A Serra Mesa travel package makes it a breeze to put together your ideal trip. With more than 550 airlines all over the world to choose from, finding convenient flights that fit your busy schedule won't be difficult. Not only that, we've got over 1,000,000 properties globally to select from. Talk about choice! No matter who you are, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Serra Mesa holidays?
Expedia has teamed up with online lender Klarna to make your next break easier on your bank balance. Paying by instalment means you can spread the costs of your dream holiday, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Browse these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then check out this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to hit that "book now" button, choose a low deposit holiday payment plan with Klarna.

Where should I stay in Serra Mesa?
A journey to Serra Mesa has to include SeaWorld and San Diego Zoo. Stay at a hotel nearby for quick access to these impressive tourist attractions.
What are the top hotels in Serra Mesa?
Book a room at Manchester Grand Hyatt San Diego. It's one of the neighbourhood's most in-demand hotels. Another reputable option in Serra Mesa is Paradise Point Resort And Spa.
How far in advance should I book my Serra Mesa holiday?
It's always wise to book early. Air carriers usually advertise flights nearly 12 months ahead of departure, and this is an excellent opportunity to score some of the lowest prices. Just been told you need to take some holiday time in a few weeks? No need to worry. Expedia are never short of fantastic deals to send you on the getaway of your dreams, at an affordable price.
What does an Expedia Serra Mesa travel package include?
Select from any combination of rental cars, flights and hotels. Once you've made your booking, you can also add on experiences and tours. Want to pick your fare class? That's also possible. The choice is yours when it comes to crafting your perfect Serra Mesa escape.
What should I know before booking a Serra Mesa travel package?
When you book your flights, hotels and car rentals together, you'll pick up amazing discounts. Whether you're planning a wilderness getaway in a cabin or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Serra Mesa Expedia travel package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines worldwide. Our packages give you the freedom to pick from available flight, hotel or activity options that suit you.

Popular places to visit

San Diego Zoo

San Diego Zoo

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.

San Diego Convention Center
Mission Bay

Mission Bay

Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Mission Bay

Things to do

LEGOLAND® California Resort

LEGOLAND® California Resort

£54
per adult
84% of travellers recommend
LEGOLAND® California Resort
San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

£65
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

£52
per adult
86% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
See all activities in San Diego

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.