Title: Serra Mesa Holidays 2026 from £937 | Expedia.co.uk [Hotels in Serra Mesa](https://expedia.co.uk/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Serra Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Serra-Mesa.d553248635953501652.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Serra Mesa Holidays from £937 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ### Your Serra Mesa Holiday Make planning your travels easier by snapping up a holiday package to Serra Mesa. Let us handle all the details, so you can concentrate on savouring everything this neighbourhood has to offer. Begin your trip to Serra Mesa by visiting nearby attractions such as [Snapdragon Stadium](https://www.expedia.co.uk/Snapdragon-Stadium-Mission-Valley.d502539.Attraction), [Fashion Valley Mall](https://www.expedia.co.uk/Fashion-Valley-Mall-Mission-Valley.d6168368.Attraction) and [Mission Valley Mall](https://www.expedia.co.uk/Mission-Valley-Mall-Mission-Valley.d6168371.Attraction). Stop daydreaming and start doing. When you're ready to book your dream holiday to Serra Mesa, Expedia will help you get there. Price found within the past 48 hours. Click for updated prices. ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Sofia Hotel Downtown San Diego Save 100% on your flight £937 per person 18 Feb - 25 Feb found 1 day ago Return flight included London (LON) to San Diego (SAN) 8.4/10 Very Good! (1,627 reviews) Overall everything was great!! From arriving to leaving. Even my son and his girlfriend stayed at the hotel and they loved it Reviewed on 19 Jan 2026 ![Beach Village at The Del, LXR Hotels & Resorts](https://images.trvl-media.com/lodging/20000000/19660000/19656500/19656437/eaeb791a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Beach Village at The Del, LXR Hotels & Resorts Historic Downtown Coronado Save 100% on your flight £2,373 per person 7 Apr - 14 Apr found 12 hours ago Return direct flight included Glasgow (GLA) to San Diego (SAN) 9.2/10 Wonderful! (118 reviews) Great staff great room. All and all a perfect 10 Reviewed on 14 Jan 2026 ![Margaritaville Hotel San Diego Gaslamp Quarter](https://images.trvl-media.com/lodging/2000000/1120000/1117700/1117693/0db99a00_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Margaritaville Hotel San Diego Gaslamp Quarter Downtown San Diego £1,179 per person 7 Apr - 14 Apr found 12 hours ago Return direct flight included Glasgow (GLA) to San Diego (SAN) 9/10 Wonderful! (1,128 reviews) Fun atmosphere and refreshing change of scenery. Staff was helpful and location is outstanding. Reviewed on 13 Jan 2026 ![Shore House at The Del, LXR Hotels & Resorts](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510728/w3840h2877x0y3-c3d52563_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Shore House at The Del, LXR Hotels & Resorts Historic Downtown Coronado Save 100% on your flight £2,371 per person 7 Apr - 14 Apr found 12 hours ago Return direct flight included Glasgow (GLA) to San Diego (SAN) 9.2/10 Wonderful! (109 reviews) All was wonderful. Have to say that after making reservations two months in advance m, I was a bit disappointed in where we were placed. I should have said something when we check in but once I got over what I was expecting, the room location was okay but the room itself was over the top. We will go again but be a bit more vocal in our room placement. But this place comes with our strong recommendation to stay. Reviewed on 12 Dec 2025 ![The Artifact Hotel](https://images.trvl-media.com/lodging/114000000/113400000/113393600/113393576/061c57c5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Artifact Hotel Downtown San Diego £1,044 per person 7 Apr - 14 Apr found 12 hours ago Return direct flight included Glasgow (GLA) to San Diego (SAN) 9.2/10 Wonderful! (44 reviews) Room was great, the hosts were fantastic and communicative. Absolutely will plan to stay here again in the future! Reviewed on 13 Nov 2025 ## Where to stay in Serra Mesa Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. [Learn more about Serra Mesa](https://expedia.co.uk/San-Diego-Serra-Mesa.dx553248635953501652) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481093-Downtown-San-Diego.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown San Diego 4 out of top 10 points of interest in this area 4.5/5(138 area reviews) Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city. [Find hotels in Downtown San Diego](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=800123) ![Gaslamp Quarter featuring a bar, night scenes and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22037-San-Diego-Gaslamp-Quarter.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Gaslamp Quarter San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs. [Find hotels in Gaslamp Quarter](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6130021) ![Pacific Beach Park showing a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152283-Pacific-Beach.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Pacific Beach 4/5(13 area reviews) Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip. [Find hotels in Pacific Beach](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=6185751) ![Belmont Park featuring a park and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22160-Belmont-Park.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Mission Beach If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing. [Find hotels in Mission Beach](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=553248635998112279) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481019-Ocean-Beach-Nei.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Ocean Beach 4.5/5(4 area reviews) Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market. [Find hotels in Ocean Beach](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Dest.PKG.Neighborhoods®ionId=177689) ## Top hotels in Serra Mesa ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton San Diego Resort 1380 Harbor Island Dr San Diego CA Fully refundableReserve now, pay when you stay £204 23 Jan - 24 Jan includes taxes & fees 8.2/10 Very Good! (3,248 reviews) I love that place !!! I will definitely come back again. Reviewed on 18 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=11109&PinnedHotelID=11109&HadPinnedHotel=true®ionId=553248635953501652) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hard Rock Hotel San Diego 207 5th Ave San Diego CA Fully refundableReserve now, pay when you stay £185 22 Jan - 23 Jan includes taxes & fees 8.8/10 Excellent! (3,236 reviews) The room was a great deal!! It was really spacious. We loved that the toilet and the shower was on two seperate sides of the bathroom.. however the bed was like sleeping on a floor, the sliding doors took extreme manpower to open so paying extra for a balcony wasnt worth it and the toilet made the ... Reviewed on 17 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F01%2F2026&endDate=23%2F01%2F2026&selected=1731557&PinnedHotelID=1731557&HadPinnedHotel=true®ionId=553248635953501652) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard by Marriott San Diego Downtown Little Italy 1646 Front St San Diego CA Fully refundableReserve now, pay when you stay £132 25 Jan - 26 Jan includes taxes & fees 8.8/10 Excellent! (233 reviews) i had an early check-in and received an upgraded room!! amazing staff! Reviewed on 12 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=25%2F01%2F2026&endDate=26%2F01%2F2026&selected=13205&PinnedHotelID=13205&HadPinnedHotel=true®ionId=553248635953501652) [See all 9,047 properties in Serra Mesa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=20%2F01%2F2026&endDate=21%2F01%2F2026®ionId=553248635953501652) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Frequently asked questions ### How much does a Serra Mesa travel package cost? ### If I'm not able to travel, can I cancel my Serra Mesa travel package? ### How do I get a cheap travel package to Serra Mesa? ### Does Expedia offer Book Now, Pay Later Serra Mesa holidays? > - Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible. > - Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then check out this Book Now, Pay Later option from Klarna. > - Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to hit that "book now" button, choose a low deposit holiday payment plan with Klarna. ### Where should I stay in Serra Mesa? ### What are the top hotels in Serra Mesa? ### How far in advance should I book my Serra Mesa holiday? ### What does an Expedia Serra Mesa travel package include? ### What should I know before booking a Serra Mesa travel package? ### Can I choose my airline with a Serra Mesa Expedia travel package? ### Popular places to visit ![San Diego Zoo featuring zoo animals, landscape views and a pond](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22060-San-Diego-Zoo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Diego Zoo 4.5/5(47 reviews) See nature up-close and personal at one of the country’s largest and most educational zoos. [](https://expedia.co.uk/San-Diego-Zoo-San-Diego.d502547.Attraction) ![San Diego Convention Center](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481325-San-Diego-Convention-Center.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Diego Convention Center 4/5(18 reviews) During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and entertainment choices. [](https://expedia.co.uk/San-Diego-Convention-Center-Downtown-San-Diego.d6125294.Attraction) ![Mission Bay featuring a beach](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/152000/152458-Mission-Bay.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mission Bay 4.5/5(31 reviews) Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park. [](https://expedia.co.uk/Mission-Bay-San-Diego.d6185904.Attraction) ### Things to do ![LEGOLAND® California Resort](https://mediaim.expedia.com/localexpert/169428/4add278e-78ce-44aa-b7e4-703b2249aec9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### LEGOLAND® California Resort £47 per adult **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/legoland-california-resort.a169428.activity-details) ![San Diego Whale Watching Tour ](https://mediaim.expedia.com/localexpert/2836808/467b4391-ac11-41ae-8823-603a9c00d22e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Diego Whale Watching & Dolphin Cruise £53 per adult **86%** of travellers recommend [](https://expedia.co.uk/things-to-do/san-diego-whale-watching-dolphin-cruise.a2836808.activity-details) ![San Diego: Luggage Storage in Marina](https://mediaim.expedia.com/localexpert/48212655/592cad7f-c489-4c0f-bd98-eadd3af5f4a9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### San Diego: Luggage Storage in Marina £7 per adult **80%** of travellers recommend [](https://expedia.co.uk/things-to-do/san-diego-luggage-storage-in-marina.a48212655.activity-details) [See all activities in San Diego](https://expedia.co.uk/things-to-do/search?rid=553248635953501652) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.