Serra Mesa Holidays from £935
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Your Serra Mesa Holiday
Make planning your travels easier by snapping up a holiday package to Serra Mesa. Let us handle all the details, so you can concentrate on savouring everything this neighbourhood has to offer. Begin your trip to Serra Mesa by visiting nearby attractions such as Snapdragon Stadium, Fashion Valley Mall and Mission Valley Mall. Stop daydreaming and start doing. When you're ready to book your dream holiday to Serra Mesa, Expedia will help you get there.
Price found within the past 48 hours. Click for updated prices.
The Sofia Hotel
Downtown San Diego
£935
per person
12 Nov - 16 Nov
just found
Return direct flight included
London (LON) to San Diego (SAN)
8.6/10 Excellent! (2,586 reviews)
We had a wonderful stay at The Sofia Hotel! The hotel has so much charm and character, and the location was incredibly convenient for everything we wanted to do in San Diego.
One thing that really stood out to us was the housekeeping. Our room was refreshed and tidied up every single day, which is something you just don’t find very often anymore! It was such a nice feeling coming back after a long day to a clean, refreshed room and a neatly made bed. Those little touches really made our stay feel special.
The staff was friendly and helpful throughout our stay, and overall we had a great experience. We would absolutely stay at The Sofia again on another trip to San Diego!
Reviewed on 9 Sept 2026
Paradise Point Resort & Spa
Mission Bay
£2,425
per person
18 Oct - 22 Oct
found 24 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.8/10 Excellent! (2,853 reviews)
This hotel is very central and a good base. The room was clean and a good size. Moving around the property is a good way to make your step mark.
Dining options are limited to 2 restaurants on premises and a market. Will recommend to bring your own snacks and water if you have a large group.
Has a marina in place and you have multiple rental options.
The views of the cove are great
Reviewed on 9 Sept 2026
Where to stay in Serra Mesa
Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Serra Mesa
Downtown San Diego
3 out of top 10 points of interest in this area
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach and Dog Beach.
Top hotels in Serra Mesa
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
£236
10 Sept - 11 Sept
includes taxes & fees
California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
£68
20 Sept - 21 Sept
includes taxes & fees
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
£216
4 Oct - 5 Oct
includes taxes & fees
8.8/10 Excellent! (2,885 reviews)
"This hotel is very central and a good base. The room was clean and a good size. Moving around the property is a good way to make your step mark. Dining options are limited to 2 restaurants on premises and a market. Will recommend to bring your own snacks and water if you have a large group. Has a ..."
Reviewed on 9 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Serra Mesa travel package cost?
Explore the best of Serra Mesa from as low as £935. Choose from a great selection of flights, hotels and rental cars to suit every budget. You can pick up even better deals when you add a few sightseeing tours to your travel package.
If I'm not able to travel, can I cancel my Serra Mesa travel package?
Whether it's your hotel or flight, yes, you can cancel or amend it. Booked your Serra Mesa travel package in the last 24 hours? You may be able to make changes for free. For bookings made more than 24 hours ago, you may incur a charge from your airline, hotel or car rental company. For more information, check out our Customer Service Portal. We're here to help you every step of the way.
How do I get a cheap travel package to Serra Mesa?
Combining your hotel and flight with Expedia won't just save you time — it'll save you cash too. A Serra Mesa travel package makes it a breeze to put together your ideal trip. With more than 550 airlines all over the world to choose from, finding convenient flights that fit your busy schedule won't be difficult. Not only that, we've got over 1,000,000 properties globally to select from. Talk about choice! No matter who you are, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Serra Mesa holidays?
Expedia has teamed up with online lender Klarna to make your next break easier on your bank balance. Paying by instalment means you can spread the costs of your dream holiday, leaving you with more money to spend while you're away. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Browse these flexible payment options:
- Pay monthly holidays: If paying bite-sized amounts each month works for you, Klarna can help. Paying in convenient monthly instalments will make that dream getaway possible.
- Pay in instalments holidays: Like the idea of paying for your holiday in multiple transactions? Then check out this Book Now, Pay Later option from Klarna.
- Low deposit holidays: If paying a small percentage of your trip (rather than the total upfront) makes it easier to hit that "book now" button, choose a low deposit holiday payment plan with Klarna.
Where should I stay in Serra Mesa?
A journey to Serra Mesa has to include SeaWorld and San Diego Zoo. Stay at a hotel nearby for quick access to these impressive tourist attractions.
What are the top hotels in Serra Mesa?
Book a room at Manchester Grand Hyatt San Diego. It's one of the neighbourhood's most in-demand hotels. Another reputable option in Serra Mesa is Paradise Point Resort And Spa.
How far in advance should I book my Serra Mesa holiday?
It's always wise to book early. Air carriers usually advertise flights nearly 12 months ahead of departure, and this is an excellent opportunity to score some of the lowest prices. Just been told you need to take some holiday time in a few weeks? No need to worry. Expedia are never short of fantastic deals to send you on the getaway of your dreams, at an affordable price.
What does an Expedia Serra Mesa travel package include?
Select from any combination of rental cars, flights and hotels. Once you've made your booking, you can also add on experiences and tours. Want to pick your fare class? That's also possible. The choice is yours when it comes to crafting your perfect Serra Mesa escape.
What should I know before booking a Serra Mesa travel package?
When you book your flights, hotels and car rentals together, you'll pick up amazing discounts. Whether you're planning a wilderness getaway in a cabin or want to stay in a fancy hotel in the city, Expedia will help make it happen.
Can I choose my airline with a Serra Mesa Expedia travel package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines worldwide. Our packages give you the freedom to pick from available flight, hotel or activity options that suit you.
Stay near popular Serra Mesa attractions
Stadium Golf Center & Batting Cages
Enjoy a round of golf in San Diego at Stadium Golf Center & Batting Cages. Attend a sporting event or discover the beautiful sunsets in this walkable area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
£42
per adult
94% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.