Santa María Holidays from £1,211

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Your Santa María Holiday

Reserve a Santa María holiday package and get set to experience all this lively city has to offer. Consider basing yourself in the neighbourhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María holiday is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

Top Santa María Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique

4 out of 5
Cartagena Walled City
Price was £1,604, price is now £1,211 per person
£1,211
per person
16 Apr - 20 Apr
found 1 day ago
Additional charges may apply
Return flight included
London (LGW) to Cartagena (CTG)
9.4/10 Exceptional! (222 reviews)
Really clean and good customer service

Reviewed on 14 Feb 2026

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive

4 out of 5
Zona Norte
Price was £2,537, price is now £1,833 per person
£1,833
per person
16 Apr - 20 Apr
found 1 day ago
Additional charges may apply
Return flight included
London (LGW) to Cartagena (CTG)
8.2/10 Very Good! (935 reviews)
Oh my goodness!! Two things…the service and the cleanliness!! Everyone was so humble and welcoming from the time we got out the taxi to enter our first day, til the time they put us back in the taxi 7 days later when we checked out!

Reviewed on 12 Feb 2026

Sofitel Legend Santa Clara Cartagena

Sofitel Legend Santa Clara Cartagena

5 out of 5
Cartagena Walled City
Price was £2,973, price is now £2,223 per person
£2,223
per person
16 Apr - 20 Apr
found 1 day ago
Additional charges may apply
Return flight included
London (LGW) to Cartagena (CTG)
9.4/10 Exceptional! (1,001 reviews)
We had a wonderful stay at Sofitel! The breakfast was delicious and the service outstanding — every staff member we met was friendly and attentive. We enjoyed the pool every day and had an amazing time with the crew who always made sure we were well taken care of. Highly recommended!

Reviewed on 16 Feb 2026

Bastión Luxury Hotel

Bastión Luxury Hotel

4.5 out of 5
Cartagena Walled City
Price was £1,638, price is now £1,282 per person
£1,282
per person
16 Apr - 20 Apr
found 1 day ago
Additional charges may apply
Return flight included
London (LGW) to Cartagena (CTG)
9.6/10 Exceptional! (1,001 reviews)
Staff were friendly & very helpful. The room was excellent with a great bed & shower. We stayed for one night at the end of our week in Cartagena

Reviewed on 14 Feb 2026

Hotel Isla del Encanto

Hotel Isla del Encanto

4 out of 5
Price was £2,541, price is now £1,777 per person
£1,777
per person
5 Apr - 11 Apr
found 7 hours ago
Additional charges may apply
Return direct flight included
London (LON) to Cartagena (CTG)
8.8/10 Excellent! (186 reviews)
The hotel is lovely and perfect for a quiet getaway! The staff is exceptional and everything

Reviewed on 3 Feb 2026

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Santa Marían Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Nunez Intl. Airport (CTG)
Max Temp Winter
32ºC
Max Temp Summer
32ºC
Top Sights
Bocagrande Beach, Marbella Beach and Playa Manzanillo

Top hotels in Santa María

InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

4 out of 5
Bocagrande Carrera 1 No. 5-01 Cartagena Bolivar
Fully refundable
The price is £134 per night from 4 Mar to 5 Mar
£134
4 Mar - 5 Mar
additional charges may apply
9.2/10 Wonderful! (1,486 reviews)
The pool it’s cover for a

Reviewed on 17 Feb 2026

InterContinental Cartagena De Indias by IHG
Hyatt Regency Cartagena

Hyatt Regency Cartagena

4.5 out of 5
Carrera 1 No 12-118 Cartagena CO
Fully refundableReserve now, pay when you stay
The price is £151 per night from 3 Mar to 4 Mar
£151
3 Mar - 4 Mar
additional charges may apply
9.2/10 Wonderful! (1,443 reviews)
Clean room and great amenities

Reviewed on 19 Feb 2026

Hyatt Regency Cartagena
Hilton Cartagena

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
The price is £133 per night from 5 Mar to 6 Mar
£133
5 Mar - 6 Mar
additional charges may apply
9/10 Wonderful! (1,352 reviews)
Very clean room.

Reviewed on 11 Feb 2026

Hilton Cartagena
See all 3,865 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Marbella Beach

4/5(1 review)

Why not spend a care-free afternoon at Marbella Beach during your travels in Cartagena? Stroll along the area's seaside or simply enjoy its restaurants.

Marbella Beach

San Felipe de Barajas Castle

4.5/5(3 reviews)

After visiting San Felipe de Barajas Castle, make a plan to see the other sights and activities in Cartagena. Wander the area's beautiful beaches or simply enjoy one of its top-notch restaurants.

San Felipe de Barajas Castle

What to do in Santa María

Cartagena Island Hopping : 5-Stop Rosario Island Tour with Lunch

Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch

£49
per adult
78% of travellers recommend
Cartagena Island Hopping: 5-Stop Rosario Islands Tour with Lunch
Cartagena ATV Tour

Cartagena ATV Tour

£99
per adult
94% of travellers recommend
Cartagena ATV Tour
Pirate Ship Boat Tour & Sunset Skyline Tour

Cartagena, CO: Sunset Skyline Bay Tour on a Pirate Boat + Drinks

£32
per adult
88% of travellers recommend
Cartagena, CO: Sunset Skyline Bay Tour on a Pirate Boat + Drinks
See all activities in Santa María

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.