Santa María Holidays from £1,789
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santa María Holiday
Reserve a Santa María holiday package and get set to experience all this lively city has to offer. Consider basing yourself in the neighbourhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María holiday is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.
Top Santa María Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Moet Cartagena Hotel Boutique - Adults Only
Cartagena Walled City
£2,252
per person
22 Dec - 29 Dec
found 1 day ago
Additional charges may apply
Return direct flight included
London (LHR) to Cartagena (CTG)
9.4/10 Exceptional! (127 reviews)
Such a beautiful place! The room was so cute, with a beach view balcony! Perfect location. I would recommend it and love to comeback!
Reviewed on 21 Sept 2026
Santa Marían Essential Information
Language | Spanish |
|---|---|
Currency | Colombian pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Rafael Nunez Intl. Airport (CTG) |
Max Temp Winter | 32ºC |
Max Temp Summer | 32ºC |
Top Sights | Bocagrande Beach, Marbella Beach and Playa Manzanillo |
Top hotels in Santa María
OZ Hotel Collection
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
£80
28 Oct - 29 Oct
additional charges may apply
Sofitel Barú Cartagena
KM 7 Sector, Porto Nao Cartagena Bolívar
Fully refundableReserve now, pay when you stay
£252
2 Nov - 3 Nov
additional charges may apply
9.4/10 Exceptional! (822 reviews)
"Clean property, SPA 10/10, it’s an hour and a half away from the airport by car and the travel is sketchy just set up transportation with the resort and you’re set. Would definitely go back!"
Reviewed on 5 Oct 2026
Dreams Karibana Cartagena Golf & Spa Resort - All Inclusive
Anillo Vial, Km 12, between Manzanillo Cartagena Bolivar
Fully refundableReserve now, pay when you stay
£234
13 Oct - 14 Oct
additional charges may apply
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in Santa María
Luxury Cartagena Sunset Pirate ship Adventure, Cannon Show&Drinks
£35
per adult
88% of travellers recommend
Cartagena 5 Island Hop Tour: Lunch, Snorkel, Beach Clubs, & More
£52
per adult
84% of travellers recommend
Cartagena: Rosario Islands and Playa Blanca Excursion with Snorkeling or Aquarium
£59
per adult
100% of travellers recommend
Frequently asked questions
How much does a Santa María travel package cost?
Starting from a low £1,789, a travel package is your gateway to low-priced travel. Customize your Santa Marían escape by choosing from our huge range of hotels, airfares and rental cars.
If I'm not able to travel, can I cancel my Santa María travel package?
Don't worry if you're rethinking your Santa María travel package — it's possible to cancel or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we're here to help.
How do I get a cheap travel package to Santa María?
Book everything all in one place with our Santa María holiday packages. You'll discover bargains on flights, hotels and more that'll keep your credit card happy and your spirit of adventure alive. And, with more than 550 airlines and 1,000,000 hotels around the world to choose from, you have countless opportunities to mix and match your own way.
Does Expedia offer Book Now, Pay Later Santa María holidays?
Expedia has partnered with online lender Klarna to make booking your next break easier on your wallet. Paying in instalments means you can spread the costs of your next big holiday, leaving you with more cash to play with while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits into your budget. Check out these flexible payment options:
- Pay monthly holidays: Klarna has easy monthly payment plans that work for all types of budgets, so you can escape on that well-earned holiday now.
- Pay in instalments holidays: If you want to pay off your getaway in multiple transactions, holidays paid in instalments might be the right option for your Book Now, Pay Later holiday through Klarna.
- Low deposit holidays: Clicking on the "book now" button is easier with this plan. Just put down a small deposit on your holiday and then start packing your suitcase.
Where should I stay in Santa María?
Urban adventurers come from all over the world to see San Felipe de Barajas Castle and San Fernando Fort in Santa María. Book yourself a room close to these awesome attractions and visit them at your leisure.
What are the top hotels in Santa María?
If it's your first time staying in Santa María, reserve a room at Hilton Cartagena or Intercontinental Cartagena De Indias. Both have good amenities and are favourites among many savvy travellers.
How far in advance should I book my Santa María holiday?
Travellers are normally able to look up international fares on Expedia up to a year in advance of departure. Booking late? With a stroke of luck, it's still possible to score an affordable ticket only weeks before your flight.
What does an Expedia Santa María travel package include?
Flights, hotels and a reliable car for all your road trip adventures. Simply select your preferred bundle and gain access to great discounts. Once you've made your booking, add on a couple of sightseeing tours and watch your savings grow. When it comes to organising your Santa María getaway, the choice is all yours!
What should I know before booking a Santa María travel package?
So many places to go, so many things to experience. With a travel package, you'll be able to cross more of them off your list. Combine your hotels, rental cars and flights and score big savings.
Can I choose my airline with a Santa Marían Expedia travel package?
With a travel package, you're in charge. Whether you're hoping to fly to Santa Marían in coach or first class, simply select from the available airline options. Expedia has access to over 550 partner airlines globally.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
