Santa María Holidays from £1,567

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Your Santa María Holiday

Reserve a Santa María holiday package and get set to experience all this lively city has to offer. Consider basing yourself in the neighbourhood of Cartagena Walled City, which is good for views, dining and bars and pubs. San Felipe de Barajas Castle, San Pedro Claver Church and Convent and Jaime Moron Stadium are just a few of the many attractions worth checking out during your trip to Santa María. That dream Santa María holiday is clicks away. Browse hotels, airfares and more on Expedia for a getaway that's tailored to suit your travel style.

Top Santa María Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Casa del Arzobispado Hotel
Charleston Santa Teresa Cartagena
Casa Carolina Luxury Wellness Hotel
Bastión Luxury Hotel
Hotel Casa San Agustin

Santa Marían Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Nunez Intl. Airport (CTG)
Max Temp Winter
32ºC
Max Temp Summer
32ºC
Top Sights
Bocagrande Beach, Marbella Beach and Playa Manzanillo

Top hotels in Santa María

Hyatt Regency Cartagena

Hyatt Regency Cartagena

4.5 out of 5
Carrera 1 No 12-118 Cartagena CO
Fully refundableReserve now, pay when you stay
The price is £155 per night from 13 Apr to 14 Apr
£155
13 Apr - 14 Apr
additional charges may apply
9.4/10 Exceptional! (1,466 reviews)
No cooking area. You get charged for items in the minibar, and it doesn’t stay super cold. It’s still a nice chill. The ice bucket is very small..

Reviewed on 9 Apr 2026

Hyatt Regency Cartagena
InterContinental Cartagena De Indias by IHG

InterContinental Cartagena De Indias by IHG

4 out of 5
Bocagrande Carrera 1 No. 5-01 Cartagena Bolivar
Fully refundable
The price is £133 per night from 26 Apr to 27 Apr
£133
26 Apr - 27 Apr
additional charges may apply
9.4/10 Exceptional! (1,582 reviews)
This property is amazing as it has a awesome breakfast,

Reviewed on 8 Apr 2026

InterContinental Cartagena De Indias by IHG
OZ Hotel Collection

OZ Hotel Collection

3.5 out of 5
6-164 Carrera 2 Cartagena
Fully refundableReserve now, pay when you stay
The price is £93 per night from 6 May to 7 May
£93
6 May - 7 May
additional charges may apply
9.6/10 Exceptional! (391 reviews)
Crowded

Reviewed on 9 Apr 2026

OZ Hotel Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

What to do in Santa María

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.