Title: TOP Boutique Hotels in Santa Cruz for 2025 | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Seville-Santa-Cruz.dx6005056)[Holiday Rentals in Seville](https://expedia.co.uk/Seville-Holiday-Rentals.d3312.Travel-Guide-HolidayRentals)[Flights to Seville](https://expedia.co.uk/Cheap-Flights-To-Seville.d3312.Travel-Guide-Flights)[Things to do in Seville](https://expedia.co.uk/Things-To-Do-In-Seville.d3312.Travel-Guide-Activities)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6005056.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6005056.Holidays-City-Breaks) ![Santa Cruz](https://images.trvl-media.com/place/6005056/76322155-c0b9-4bf9-8b7b-37408ab9b072.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Boutique Hotels Tonight [12 Nov - 13 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6005056&startDate=2025-11-12&endDate=2025-11-13&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Nov - 14 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6005056&startDate=2025-11-13&endDate=2025-11-14&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6005056&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6005056&startDate=2025-11-21&endDate=2025-11-23&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Cruz Boutique Hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/9900/9805/42f0cb8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/9900/9805/215a48d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, steam room, Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/1000000/10000/9900/9805/09c2d373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9805/d041f704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Casas de la Judería, Sevilla Historic City Center Historical Center 9.2/10 Wonderful (1005) "A fantastic hotel with so much charm .. A beautiful room with a hydro bath which was very much enjoyed after 18000 steps …" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) James £100 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Seville-Hotels-Las-Casas-De-La-Juderia.h9805.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3100000/3096200/3096166/3d0ebbc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3100000/3096200/3096166/790497b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | Jetted bathtub](https://images.trvl-media.com/lodging/4000000/3100000/3096200/3096166/f088c3ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/4000000/3100000/3096200/3096166/a9445193.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Amadeus Sevilla Historical Center 9.6/10 Exceptional (1058) "Excellent hotel. Location was perfect, hotel delightful and whole stay was outstanding. Great breakfast, helpful staff and lovely, clean and comfortable room." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Susan Elizabeth £114 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Seville-Hotels-Hotel-Amadeus.h3096166.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/3000000/2540000/2534500/2534479/89c7c7fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/3000000/2540000/2534500/2534479/71979fd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2540000/2534500/2534479/fada5620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite (hydromassage bathtub) | 20 bedrooms, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/3000000/2540000/2534500/2534479/7c6c1e0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Rey Moro Hotel Boutique Historical Center 9.4/10 Exceptional (889) "Staff was so helpful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanna £95 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Seville-Hotels-El-Rey-Moro-Hotel-Boutique.h2534479.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/4000000/3610000/3606700/3606650/d80cc962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Single Room | Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/4000000/3610000/3606700/3606650/e8c6cae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 20 per person)](https://images.trvl-media.com/lodging/4000000/3610000/3606700/3606650/3f8388cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3610000/3606700/3606650/fac1f817.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eurostars Sevilla Boutique Historical Center 9.0/10 Wonderful (480) "Beautiful hotel , big nice room really comfortable . Very friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica £78 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Seville-Hotels-Eurostars-Sevilla-Boutique.h3606650.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/8000000/7600000/7596900/7596882/eb8fd9af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (Outside the main building) | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/8000000/7600000/7596900/7596882/55d53bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7600000/7596900/7596882/7f4e121a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7600000/7596900/7596882/0d0fb70b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Casa del Poeta Sevilla Historical Center 9.8/10 Exceptional (847) "We had a great time there with a friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nousheen £165 includes taxes & fees 6 Dec - 7 Dec [](https://www.expedia.co.uk/Seville-Hotels-Hotel-Casa-Del-Poeta.h7596882.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/11000000/10020000/10018000/10017901/556e55e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10020000/10018000/10017901/4f158aad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | View from room](https://images.trvl-media.com/lodging/11000000/10020000/10018000/10017901/9de7fff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/10020000/10018000/10017901/d3dcda46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Palacio Pinello Historical Center 9.4/10 Exceptional (672) "Super helpful staff - especially Laura and Rodrigo!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) John £96 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Seville-Hotels-Hotel-Boutique-Palacio-Pinello.h10017901.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/2000000/1910000/1901800/1901701/8b75801c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1910000/1901800/1901701/a9be631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/2000000/1910000/1901800/1901701/1fb9b2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite Views | City view](https://images.trvl-media.com/lodging/2000000/1910000/1901800/1901701/82daf4e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EME Catedral Mercer Hotel Historical Center 8.8/10 Excellent (1001) "A great hotel in a fabulous location. We thoroughly enjoyed our stay. Most of the staff were excellent and very helpful and friendly. A small criticism would be on the breakfast, which is quite moderate in terms of range and quality. But we would certainly stay here again. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Leo Roderick £136 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Seville-Hotels-EME-Catedral-Hotel.h1901701.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/980600/980523/0b60b002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/980600/980523/090243be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/990000/980600/980523/530a8e19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/990000/980600/980523/bb43d3b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Seises Sevilla, a Tribute Portfolio Hotel Historical Center 8.4/10 Very good (498) "Get location and beautiful hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leandro £126 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Seville-Hotels-Fontecruz-Sevilla-Seises.h980523.Hotel-Information) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/22000000/21900000/21890400/21890345/366265b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room, Terrace | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/22000000/21900000/21890400/21890345/5989757c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/22000000/21900000/21890400/21890345/a8e3bf41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/22000000/21900000/21890400/21890345/62e22ed3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Halo Boutique Hotel Historical Center 9.0/10 Wonderful (439) "Very central location. Staff friendly. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) John [](https://www.expedia.co.uk/Seville-Hotels-Halo-Boutique-Hotel.h21890345.Hotel-Information) ![Daily buffet breakfast (EUR 18 per person)](https://images.trvl-media.com/lodging/3000000/2850000/2847200/2847141/01840db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Ground Floor | Minibar, in-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/3000000/2850000/2847200/2847141/bf9dd363.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2850000/2847200/2847141/4200d043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2850000/2847200/2847141/72fc0a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Casas de Santa Cruz Historical Center 8.4/10 Very good (250) "Great location, nice room, friendly staff and reasonable pricing. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Alice [](https://www.expedia.co.uk/Seville-Hotels-Hotel-Boutique-Casas-De-Santa-Cruz.h2847141.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27®ionId=6005056&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Hotel Reviews ![Hotel Alcántara](//images.trvl-media.com/lodging/3000000/2690000/2687200/2687132/49078a5d_y.jpg) ### Hotel Alcántara 10/10 Excellent "Very friendly staff, always on call, the bed probably one of the most comfortable Ive ever slept on. Plenty of toiletries and maid in daily" [](https://expedia.co.uk/Seville-Hotels-Hotel-Alcantara.h2687132.Hotel-Information) ![Hotel Amadeus Sevilla](//images.trvl-media.com/lodging/4000000/3100000/3096200/3096166/3d0ebbc8_y.jpg) ### Hotel Amadeus Sevilla 10/10 Excellent "Excellent hotel. Location was perfect, hotel delightful and whole stay was outstanding. Great breakfast, helpful staff and lovely, clean and comfortable room." [](https://expedia.co.uk/Seville-Hotels-Hotel-Amadeus.h3096166.Hotel-Information) ![EME Catedral Mercer Hotel](//images.trvl-media.com/lodging/2000000/1910000/1901800/1901701/8b75801c_y.jpg) ### EME Catedral Mercer Hotel 10/10 Excellent "Great staff. Very clean room. We were big fans of the rooftop bar and hotel’s location. " [](https://expedia.co.uk/Seville-Hotels-EME-Catedral-Hotel.h1901701.Hotel-Information) ![Hotel Doña Maria](//images.trvl-media.com/lodging/2000000/1180000/1177700/1177678/ecf448a5_y.jpg) ### Hotel Doña Maria 10/10 Excellent "Lovely room, staff were great" [](https://expedia.co.uk/Seville-Hotels-Hotel-Dona-Maria.h1177678.Hotel-Information) ![Hotel Boutique Palacio Pinello](//images.trvl-media.com/lodging/11000000/10020000/10018000/10017901/556e55e8_y.jpg) ### Hotel Boutique Palacio Pinello 10/10 Excellent "Great location Clean room with daily service " [](https://expedia.co.uk/Seville-Hotels-Hotel-Boutique-Palacio-Pinello.h10017901.Hotel-Information) ![Las Casas de la Judería, Sevilla Historic City Center](//images.trvl-media.com/lodging/1000000/10000/9900/9805/42f0cb8c_y.jpg) ### Las Casas de la Judería, Sevilla Historic City Center 10/10 Excellent "A fantastic hotel with so much charm .. A beautiful room with a hydro bath which was very much enjoyed after 18000 steps …" [](https://expedia.co.uk/Seville-Hotels-Las-Casas-De-La-Juderia.h9805.Hotel-Information) ![Eurostars Sevilla Boutique](//images.trvl-media.com/lodging/4000000/3610000/3606700/3606650/d80cc962_y.jpg) ### Eurostars Sevilla Boutique 10/10 Excellent "Beautiful hotel , big nice room really comfortable . Very friendly staff " [](https://expedia.co.uk/Seville-Hotels-Eurostars-Sevilla-Boutique.h3606650.Hotel-Information) ![Hotel Rey Alfonso X](//images.trvl-media.com/lodging/1000000/920000/917100/917067/927628c0_y.jpg) ### Hotel Rey Alfonso X 10/10 Excellent "Great location. Walkable to many attractions and good dining" [](https://expedia.co.uk/Seville-Hotels-Hotel-Rey-Alfonso-X.h917067.Hotel-Information) ![Hotel Murillo](//images.trvl-media.com/lodging/2000000/1430000/1427000/1426919/908c5e0f_y.jpg) ### Hotel Murillo 10/10 Excellent "The hotel was perfect, very neat and clean. We took the breakfast buffet. Had many different croissants, pastries, bread, beverages. The staff is friendly. While checking out of the hotel, they called taxi for us. Loved our stay. " [](https://expedia.co.uk/Seville-Hotels-Hotel-Murillo.h1426919.Hotel-Information) ## Frequently asked questions ### Searching for a cosy accommodation option when you visit Santa Cruz? > A boutique hotel may be just what you want if you enjoy smaller hotels with quality service and a cool atmosphere. Select from 17 boutique-style accommodation options in Santa Cruz to find a property that characterises the local flavour of this destination. ### What's the best boutique-style accommodation in Santa Cruz? > [Las Casas de la Judería, Sevilla Historic City Center](https://www.expedia.co.uk/Seville-Hotels-Las-Casas-De-La-Juderia.h9805.Hotel-Information) is a favourite hotel with Expedia travellers looking for a stylish stay, and features a full-service spa and a seasonal outdoor pool. [Hotel Amadeus Sevilla](https://www.expedia.co.uk/Seville-Hotels-Hotel-Amadeus.h3096166.Hotel-Information) and [EME Catedral Mercer Hotel](https://www.expedia.co.uk/Seville-Hotels-EME-Catedral-Hotel.h1901701.Hotel-Information) are a couple of other boutique hotels. ### How many boutique hotels should I expect to find in Santa Cruz? > Expedia has 17 boutique hotels in Santa Cruz. ### What's there to see and do in Santa Cruz? > Visitors speak positively about this destination's fantastic nightlife, cultural attractions and stunning cathedral. Activities and attractions to experience around Santa Cruz include Convent of the Incarnation, Giralda Tower and General Archive of the Indies. While you're here, you might also like to explore more of the area and take in additional sights like Triunfo Plaza, El Giraldillo and Cabildo Catedral. ### What's the best way to get to my boutique hotel in Santa Cruz? > You have a few options for travelling to and around Santa Cruz. The closest major airport is Seville (SVQ-San Pablo), which is located 5.7 mi (9.1 km) away. 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[Book Hotels in Santa Cruz on Expedia.es](https://www.expedia.es/Santa-Cruz-Sevilla-Hoteles-Hotel-Con-Encanto.0-n6005056-0-tHotelconencanto.Guia-Viajes-Filter-Hoteles)