Santa Cruz Holidays from £268

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your Santa Cruz Holiday

Book a Santa Cruz holiday package and discover the rhythm and way of life of this fascinating neighbourhood. With all your travel plans worked out, the only thing you need to focus on here is having a great time. Your trip to Santa Cruz wouldn't be complete without stopping by major attractions nearby such as Seville Cathedral, Alcázar and Plaza de España. Expedia can help you turn your ideal Santa Cruz holiday into reality, no matter your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
Hotel Cervantes

Hotel Cervantes

4 out of 5
Historical Center
per person
1 Nov - 6 Nov
found 1 day ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
9.2/10 Wonderful! (1,000 reviews)
A real beautiful hotel in the heart of the old town!

Reviewed on 16 Aug 2025

Aguilas5 SevillaSuites

Aguilas5 SevillaSuites

4 out of 5
Historical Center
per person
1 Nov - 6 Nov
found 1 day ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
10/10 Exceptional! (515 reviews)
It was cozy and very close to many restaurants and grocery stores The staff were extremely helpful I usually don’t bother with ratings but this place definitely deserves some accolades 👏👏👏

Reviewed on 13 Aug 2025

Hotel Boutique Triana House

Hotel Boutique Triana House

3 out of 5
Triana
Save 100% on your flight
per person
10 Oct - 16 Oct
found 13 hours ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
9.6/10 Exceptional! (25 reviews)
I absolutely LOVED Triana House, I almost want to gate keep it! It's one of the best hotels I've ever stayed in. The interior design was STUNNING! I will definitely stay here next time I'm in Seville.

Reviewed on 27 May 2025

Hotel Vincci Molviedro Suites Apartments

Hotel Vincci Molviedro Suites Apartments

4 out of 5
Historical Center
Save 100% on your flight
per person
10 Oct - 16 Oct
found 13 hours ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
9.8/10 Exceptional! (94 reviews)
Pros: On a beautiful relatively quiet plaza. Staff is excellent. Restaurant on site had great food with excellent service. In a great central location. Nicely furnished apartment suites with terrace. Cons: There was an odor in building 3- smelled like pipes/sewer. We were moved to building 2; the hotel upgraded us to a larger apartment- No odor there. But you can smell at times it throughout the old city. Overall: Very nice stay. Would recommend.

Reviewed on 31 May 2025

Hotel Colón Gran Meliá

Hotel Colón Gran Meliá

5 out of 5
Historical Center
Save 100% on your flight
per person
1 Nov - 6 Nov
found 1 day ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
9.6/10 Exceptional! (1,001 reviews)
we really enjoyed our stay at the Hotel Colon Gran Melia great service, great location, attentive staff, luxurious and warm interior are suiting and relaxing for a comfy and relaxing stay

Reviewed on 15 Aug 2025

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Default Image

Historical Center

7 out of top 10 points of interest in this area
4.5/5(626 area reviews)

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Top hotels in Santa Cruz

Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is £103 per night from 19 Aug to 20 Aug
£103
19 Aug - 20 Aug
includes taxes & fees
9.4/10 Exceptional! (1,037 reviews)
"Can’t fault this hotel, everything was so easy, we checked in early as they said our room was ready which was nice, staff all so lovely. Pool wasn’t too busy each day when we went always got a bed. Would defo come back"

Reviewed on 14 Aug 2025

Hotel Rey Alfonso X
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is £95 per night from 31 Aug to 1 Sept
£95
31 Aug - 1 Sept
includes taxes & fees
9.6/10 Exceptional! (1,518 reviews)
"Comfortable beds, excellent room and bathroom. Adorable staff especially Sara and Juan Antonio.."

Reviewed on 15 Aug 2025

Hotel Fernando III
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6, Seville, Seville
Fully refundableReserve now, pay when you stay
The price is £100 per night from 18 Aug to 19 Aug
£100
18 Aug - 19 Aug
includes taxes & fees
9.6/10 Exceptional! (1,003 reviews)
"It was hard to find the place"

Reviewed on 13 Aug 2025

Hotel Amadeus Sevilla
See all 422 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Cruz travel package cost?
Go from looking to booking with our Santa Cruz travel packages, which start from a low £268. Choose the flights and hotels that suit your style. Then, add on one or two tours or experiences for a one-of-a-kind getaway.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Whether it's your hotel or flight, yes, you can amend or cancel it. Locked in your Santa Cruz travel package in the last 24 hours? You may be able to make changes at no cost. For older bookings, you may incur a charge from your hotel, airline or car rental company. For more information, check out our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Santa Cruz?
Bundle your flight and hotel bookings, throw in extras such as tours, and save with a Santa Cruz travel package. You won't just walk away with superb discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 air carriers and 1,000,000 hotels across the globe. Your dream holiday starts right here, right now!
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Your bank balance shouldn't get in the way of going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book your dream getaway without draining your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has easy monthly payment plans that suit all types of budgets, so you can have that well-earned holiday now.
  • Pay in instalments holidays: If you want to pay for your getaway in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than all of it upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan with Klarna.

Where should I stay in Santa Cruz?
A visit to Santa Cruz isn't complete without stopping by Seville Cathedral and Alcazar. Stay as close as possible for quick access to these famous attractions.
What are the top hotels in Santa Cruz?
If it's your first visit to Santa Cruz, secure a room at Hotel Sevilla Centre or Hotel Alfonso XIII, a Luxury Collection Hotel, Seville. Both offer friendly service and are favourites among many savvy travellers.
How far in advance should I book my Santa Cruz holiday?
While prices fluctuate, we generally recommend reserving your seat as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If circumstances have left you booking last minute, you might still be in luck. Cheaper tickets to Santa Cruz sometimes emerge just weeks before departure.
What does an Expedia Santa Cruz travel package include?
It's up to you! You can choose from a variety of Santa Cruz packages, such as a rental car, flight and hotel. You can also book a hotel with a flight, or a flight with a rental car. Once you've made your booking, you can add on the fun stuff like activities and tours. Whatever your perfect Santa Cruz holiday looks like, get ready to save!
What should I know before booking a Santa Cruz travel package?
You can save big by combining your hotels, flights and rental cars. Once you've created your package, you can add on things like activities or tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes, and with over 550 airlines to pick from throughout the world, you're spoiled for choice. Take a look at the available options and find out which airline suits your needs and budget.

Popular places to visit

Alcazar which includes a church or cathedral and religious aspects

Royal Alcázar of Seville

Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

Royal Alcázar of Seville
Giralda Tower featuring heritage architecture and château or palace

Giralda Tower

Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.

Giralda Tower
San Telmo Palace

San Telmo Palace

Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.

San Telmo Palace

Things to do

Skip the Line Seville Alcázar, Cathedral & Giralda Guided Tour

Skip the Line Seville Alcázar, Cathedral & Giralda Guided Tour

£47
per adult
100% of travellers recommend
Skip the Line Seville Alcázar, Cathedral & Giralda Guided Tour
Seville: Flamenco Show with Optional Flamenco Museum Ticket

Seville: Puro Flamenco Show with Optional Museum Ticket

£22
per adult
98% of travellers recommend
Seville: Puro Flamenco Show with Optional Museum Ticket
Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

£28
per adult
92% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
See all activities in Seville

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.