
Santa Cruz Holidays from £240
Book a Hotel + Flight or Car together to unlock savings
Your Santa Cruz Holiday
Book a Santa Cruz holiday package and discover the rhythm and way of life of this fascinating neighbourhood. With all your travel plans worked out, the only thing you need to focus on here is having a great time. Your trip to Santa Cruz wouldn't be complete without stopping by major attractions nearby such as Seville Cathedral, Alcázar and Plaza de España. Expedia can help you turn your ideal Santa Cruz holiday into reality, no matter your budget or travel plans.

Eurostars Palace Hotel
Reviewed on 1 Jul 2025


Casa Palacio La Casa Blanca Suites
Reviewed on 20 Jun 2025

Eurostars Azahar Hotel
Reviewed on 17 Jun 2025

Triana House
Reviewed on 6 Jun 2025
Where to stay in Santa Cruz

Historical Center
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Top hotels in Santa Cruz

Reviewed on 28 Jun 2025

Reviewed on 26 Jun 2025

Reviewed on 30 Jun 2025
Frequently asked questions
Popular places to visit

Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

Giralda Tower
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.

San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do

Skip the Line Seville Alcázar, Cathedral & Giralda Guided Tour

Seville: Puro Flamenco Show with Optional Museum Ticket

Cathedral & Alcázar of Seville Guided Tour Combo
More trip options
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.