Santa Cruz Holidays from £336
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Your Santa Cruz Holiday
Book a Santa Cruz holiday package and discover the rhythm and way of life of this fascinating neighbourhood. With all your travel plans worked out, the only thing you need to focus on here is having a great time. Your trip to Santa Cruz wouldn't be complete without stopping by major attractions nearby such as Seville Cathedral, Alcázar and Plaza de España. Expedia can help you turn your ideal Santa Cruz holiday into reality, no matter your budget or travel plans.
Price found within the past 48 hours. Click for updated prices.
Aguilas5 SevillaSuites
Historical Center
£336
per person
11 Dec - 14 Dec
found 3 hours ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
10/10 Exceptional! (530 reviews)
The accommodations were clean, the check in was smooth, and our specific room had a kitchenette with utensils and large fridge. German (Herman) and Jose were outstanding. They are quick to answer questions via WhatsApp or in the lobby. The best part of our stay is the location! A 10 minute walk to Alcazar and the Cathedral, and the “waffle” looking structure. Lots of restaurants downstairs. And Carrefour a few steps away. The suites5 was perfect for our stay in Seville!
Reviewed on 9 Aug 2026
Basic Hotel Doña Manuela
Historical Center
£361
per person
13 Nov - 20 Nov
found 2 hours ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
9.2/10 Wonderful! (577 reviews)
Great location next to old town. Lots of bars and restaurants nearby. Name says everything about the accommodation, it was ok. We stayed two nights.
Reviewed on 7 Oct 2026
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
El Arenal
Book a holiday in El Arenal to discover one of the most lively neighbourhoods in the Andalusian capital.
Alfalfa
Unique features of Alfalfa include the bars and historical sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.
Triana
Get lost in the narrow lanes of the city’s old Roma quarter, known for its flamenco history and ceramics workshops.
San Bartolomé
Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Top hotels in Santa Cruz
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
£166
3 Nov - 4 Nov
includes taxes & fees
9.2/10 Wonderful! (1,013 reviews)
"These reviews said it was "unique" and "quirky" That's true if by quirky you mean quirky like your grandmother's attic. The whole hotel smells like a used clothing store and the room decor and blankets and bed are like a grandparents room. Creaky bed. Old blankets with ugly flowers. Musty. We walked ..."
Reviewed on 8 Oct 2026
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
£571
6 Nov - 7 Nov
includes taxes & fees
Hotel Amadeus Sevilla
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
£153
4 Nov - 5 Nov
includes taxes & fees
9.6/10 Exceptional! (1,287 reviews)
"Hotel is stylish, clean, and helpful. Highly recommended."
Reviewed on 7 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz travel package cost?
Go from looking to booking with our Santa Cruz travel packages, which start from a low £336. Choose the flights and hotels that suit your style. Then, add on one or two tours or experiences for a one-of-a-kind getaway.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Whether it's your hotel or flight, yes, you can amend or cancel it. Locked in your Santa Cruz travel package in the last 24 hours? You may be able to make changes at no cost. For older bookings, you may incur a charge from your hotel, airline or car rental company. For more information, check out our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Santa Cruz?
Bundle your flight and hotel bookings, throw in extras such as tours, and save with a Santa Cruz travel package. You won't just walk away with superb discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 air carriers and 1,000,000 hotels across the globe. Your dream holiday starts right here, right now!
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Your bank balance shouldn't get in the way of going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book your dream getaway without draining your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:
- Pay monthly holidays: Klarna has easy monthly payment plans that suit all types of budgets, so you can have that well-earned holiday now.
- Pay in instalments holidays: If you want to pay for your getaway in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
- Low deposit holidays: If paying a small percentage of your trip (rather than all of it upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan with Klarna.
Where should I stay in Santa Cruz?
A visit to Santa Cruz isn't complete without stopping by Seville Cathedral and Alcazar. Stay as close as possible for quick access to these famous attractions.
What are the top hotels in Santa Cruz?
If it's your first visit to Santa Cruz, secure a room at Hotel Sevilla Centre or Hotel Alfonso XIII, a Luxury Collection Hotel, Seville. Both offer friendly service and are favourites among many savvy travellers.
How far in advance should I book my Santa Cruz holiday?
While prices fluctuate, we generally recommend reserving your seat as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If circumstances have left you booking last minute, you might still be in luck. Cheaper tickets to Santa Cruz sometimes emerge just weeks before departure.
What does an Expedia Santa Cruz travel package include?
It's up to you! You can choose from a variety of Santa Cruz packages, such as a rental car, flight and hotel. You can also book a hotel with a flight, or a flight with a rental car. Once you've made your booking, you can add on the fun stuff like activities and tours. Whatever your perfect Santa Cruz holiday looks like, get ready to save!
What should I know before booking a Santa Cruz travel package?
You can save big by combining your hotels, flights and rental cars. Once you've created your package, you can add on things like activities or tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes, and with over 550 airlines to pick from throughout the world, you're spoiled for choice. Take a look at the available options and find out which airline suits your needs and budget.
Stay near popular Santa Cruz attractions
Royal Alcázar of Seville
9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
9.4/10 (6,353 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
Triunfo Plaza
9.6/10 (18 reviews)
From this ancient and picturesque square, access some of the oldest and most impressive buildings in Seville, including the world’s largest gothic cathedral.
University of Seville
8.6/10 (1,316 reviews)
Explore the campus of University of Seville during your travels in Paseo de Las Delicias. Visit the stunning cathedral and shops in this culturally rich area.
Santa Cruz Church
8.6/10 (26 reviews)
After visiting Santa Cruz Church, make a plan to see the other sights and activities in Seville. Visit the shops and top-notch restaurants in this romantic area.
Santa María la Blanca Church
8.4/10 (8 reviews)
After visiting Santa María la Blanca Church, make a plan to see the other sights and activities in Seville. Visit the stunning cathedral and top-notch restaurants in this culturally rich area.
General Archive of the Indies
8.0/10 (11 reviews)
You can study the exhibits at General Archive of the Indies, a museum with a story of its own, during your travels to Seville. Visit the stunning cathedral and lively bars in this culturally rich area.
Murillo Gardens
9.2/10 (9 reviews)
Explore the great outdoors at Murillo Gardens, a lovely green space in Seville. Visit the shops and stunning cathedral in this romantic area.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
£26
per adult
88% of travellers recommend
Seville: Setas de Sevilla Entry Ticket
£14
per adult
80% of travellers recommend
Seville: Private City Tour by Eco Tuk Tuk
£41
per adult
80% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.