Santa Cruz Holidays from £316

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Your Santa Cruz Holiday

Book a Santa Cruz holiday package and discover the rhythm and way of life of this fascinating neighbourhood. With all your travel plans worked out, the only thing you need to focus on here is having a great time. Your trip to Santa Cruz wouldn't be complete without stopping by major attractions nearby such as Seville Cathedral, Alcázar and Plaza de España. Expedia can help you turn your ideal Santa Cruz holiday into reality, no matter your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
Eurostars Al-Ándalus Palace

Eurostars Al-Ándalus Palace

4 out of 5
Bellavista-La Palmera
Save 100% on your flight
Price was £500, price is now £316 per person
£316
per person
21 Sept - 25 Sept
found 1 day ago
Return flight included
Birmingham (BHX) to Seville (SVQ)
8.6/10 Excellent! (1,262 reviews)
Good stay and nice breakfast. Pool hours is strange, as a guest I am away during the day and will not be able to use it

Reviewed on 8 Jul 2026

Aguilas5 SevillaSuites

Aguilas5 SevillaSuites

4 out of 5
Historical Center
Price was £948, price is now £362 per person
£362
per person
8 Aug - 13 Aug
found 19 hours ago
Return flight included
Manchester (MAN) to Seville (SVQ)
10/10 Exceptional! (528 reviews)
Service was great. They were very response and addressed our concerns. But the property is more 3 stars than 4. We had two small beds together in one room. My wife’s bed was slipping from the end so 20-30 pct was unusable and mattress should be replaced. Bathroom also had duct tape on the ceiling and the shower is barely 2 feet wide. I couldn’t shower without hitting my hand somewhere. Location is great but I wouldn’t stay here again. Would look for an actual 4 star hotel.

Reviewed on 5 Apr 2026

Apartamentos Metrópolis Sevilla

Apartamentos Metrópolis Sevilla

3 out of 5
Historical Center
Save 100% on your flight
Price was £660, price is now £364 per person
£364
per person
16 Sept - 22 Sept
found 23 hours ago
Return flight included
London (LON) to Seville (SVQ)
8.8/10 Excellent! (186 reviews)
The apartment is clean, organized and has everything you need. It is close to city center where you find bars and restaurants. Front desk is so nice and helpful.. Excellent place to stay in Sevilla .

Reviewed on 2 May 2026

Eurostars Palace Hotel

Eurostars Palace Hotel

5 out of 5
Distrito Centro
Save 100% on your flight
Price was £537, price is now £319 per person
£319
per person
21 Sept - 25 Sept
found 1 day ago
Return flight included
London (LON) to Seville (SVQ)
9/10 Wonderful! (1,002 reviews)
What a great find in Cordoba. Staff could not be more helpful or professional. Would definitely stay again. Very good quality underground on-site parking.

Reviewed on 26 Jun 2026

Hotel Exe Isla Cartuja

Hotel Exe Isla Cartuja

4 out of 5
Triana
Save 100% on your flight
Price was £529, price is now £333 per person
£333
per person
22 Aug - 27 Aug
found 1 day ago
Return flight included
London (LON) to Seville (SVQ)
7.6/10 Good! (644 reviews)
Perfect place if you need to go to the Cartuja. Hotel is good and the staff is very helpful.

Reviewed on 6 Jul 2026

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
A tree-lined street with parked motorcycles and cars, and a person walking.

Historical Center

7 out of top 10 points of interest in this area
4.5/5(631 area reviews)

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Find hotels in Historical Center

Top hotels in Santa Cruz

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
The price is £352 per night from 2 Aug to 3 Aug
£352
2 Aug - 3 Aug
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
"An utterly beautiful hotel. The staff were just amazingy friendly and helpful, the location was perfect and the food was exceptional. The facilities were also fantastic The pool - which has a great balance of shaded and full sunshine sun beds- was a godsend when it got hot! All in all the perfect ..."

Reviewed on 27 Jun 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
The price is £107 per night from 8 Aug to 9 Aug
£107
8 Aug - 9 Aug
includes taxes & fees
9.2/10 Wonderful! (1,009 reviews)
"Exceptional and historically unique property, quite beautiful and very well-located in the historic center of Seville. Exploring the hotel's grounds itself was fun and interesting - an adventure on its own. Many inviting patio spaces where one can sit and relax with a drink and/or meal. Even the ..."

Reviewed on 8 Jul 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
The price is £41 per night from 3 Aug to 4 Aug
£41
3 Aug - 4 Aug
includes taxes & fees
8.8/10 Excellent! (1,014 reviews)
"Lovely cute hotel on a pretty, narrow street. Lovely lady checked us in, Miriam, I think. Room was small but clean. Bed and pillows comfy. Fridge with water which was restocked daily. Kettle and tea/coffee. Roomy, very clean bathroom, shower was over the bath but worked well. Small bottles of shower ..."

Reviewed on 9 Jul 2026

Hotel Murillo
See all 413 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Santa Cruz travel package cost?
Go from looking to booking with our Santa Cruz travel packages, which start from a low £316. Choose the flights and hotels that suit your style. Then, add on one or two tours or experiences for a one-of-a-kind getaway.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
Whether it's your hotel or flight, yes, you can amend or cancel it. Locked in your Santa Cruz travel package in the last 24 hours? You may be able to make changes at no cost. For older bookings, you may incur a charge from your hotel, airline or car rental company. For more information, check out our Customer Service Portal. We'll help you each step of the way.
How do I get a cheap travel package to Santa Cruz?
Bundle your flight and hotel bookings, throw in extras such as tours, and save with a Santa Cruz travel package. You won't just walk away with superb discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 air carriers and 1,000,000 hotels across the globe. Your dream holiday starts right here, right now!
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Your bank balance shouldn't get in the way of going on holiday, so Expedia has devised a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book your dream getaway without draining your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Klarna has easy monthly payment plans that suit all types of budgets, so you can have that well-earned holiday now.
  • Pay in instalments holidays: If you want to pay for your getaway in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: If paying a small percentage of your trip (rather than all of it upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan with Klarna.

Where should I stay in Santa Cruz?
A visit to Santa Cruz isn't complete without stopping by Seville Cathedral and Alcazar. Stay as close as possible for quick access to these famous attractions.
What are the top hotels in Santa Cruz?
If it's your first visit to Santa Cruz, secure a room at Hotel Sevilla Centre or Hotel Alfonso XIII, a Luxury Collection Hotel, Seville. Both offer friendly service and are favourites among many savvy travellers.
How far in advance should I book my Santa Cruz holiday?
While prices fluctuate, we generally recommend reserving your seat as early as possible. Most international airfares can be compared on Expedia up to 12 months in advance. If circumstances have left you booking last minute, you might still be in luck. Cheaper tickets to Santa Cruz sometimes emerge just weeks before departure.
What does an Expedia Santa Cruz travel package include?
It's up to you! You can choose from a variety of Santa Cruz packages, such as a rental car, flight and hotel. You can also book a hotel with a flight, or a flight with a rental car. Once you've made your booking, you can add on the fun stuff like activities and tours. Whatever your perfect Santa Cruz holiday looks like, get ready to save!
What should I know before booking a Santa Cruz travel package?
You can save big by combining your hotels, flights and rental cars. Once you've created your package, you can add on things like activities or tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Cruz Expedia travel package?
Yes, and with over 550 airlines to pick from throughout the world, you're spoiled for choice. Take a look at the available options and find out which airline suits your needs and budget.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
See properties

Things to do

From Seville: Ronda and Setenil de las Bodegas Day Trip

From Seville: Setenil & Ronda+Flamenco Show

£39
per adult
90% of travellers recommend
From Seville: Setenil & Ronda+Flamenco Show
Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

£26
per adult
90% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
Boat Trip "Los Rincones del Guadalquivir"

Boat Trip "Los Rincones del Guadalquivir"

£22
per adult
88% of travellers recommend
Boat Trip "Los Rincones del Guadalquivir"
See all activities in Seville

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.