Title: Holiday Rentals Santa Clara from £66: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in Santa Clara](https://expedia.co.uk/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Santa Clara Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Clara.d553248623287315690.Car-Hire-Guide)[Santa Clara Holidays](https://expedia.co.uk/Santa-Clara.d553248623287315690.Holidays-City-Breaks) ![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [8 May - 10 May](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [5 Jun - 7 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [3 Jul - 5 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Clara holiday rentals ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (235 reviews) "Really loved this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandra £124 includes taxes & fees 20 Mar - 21 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Aparta Suite [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 8.4/10 Very good (7 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto £72 includes taxes & fees 12 Mar - 13 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Private beach](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/30ff294e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/e0ba1e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/87c35f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/e0ea3259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Habitación con entrada Privada en Playa Dorada + Kitchenette y baño. [](https://www.expedia.co.uk/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information) Vacamonte 10/10 Exceptional (2 reviews) "Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia £24 includes taxes & fees 20 Mar - 21 Mar [](https://www.expedia.co.uk/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/87d5a99d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/be270857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/c9888658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/123000000/122660000/122657100/122657050/1cbda3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Living 73 Panamá by Boutique Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) San Francisco £156 includes taxes & fees 18 Mar - 19 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Living-73.h122657050.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (10C) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 7.8/10 Good (33 reviews) "The place was clean nice an its comfortable an the view is to kill for amazing ‼️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Odaine [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/2f0279c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/4d9b3d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centriqo by Wynwood house [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) Veracruz £107 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/db18ada2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (Queen) | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/f680e3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, Annex Building (King) | Living area | 42-inch flat-screen TV with digital channels, TV](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) Casco Viejo 10/10 Exceptional (182 reviews) "Excellent place to stay in the Casco Viejo " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zoe M [](https://www.expedia.co.uk/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (77 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris £93 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/46eb55a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/3b43323d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/3b2566fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114580500/114580453/267d4c66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wanders Panama by Boutique Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information) San Francisco 10/10 Exceptional (3 reviews) "The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £239 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Wanders-Panama-By-Boutique-Apartments.h114580453.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Bella Vista 8.8/10 Excellent (515 reviews) "Excellent place, friendly staff, great breakfast and many shops close by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Apartment (14D) | Dining room](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/2a0412bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/b89161f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11F) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/3115996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (5E) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/e5dc9f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mini Design By Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) Bella Vista £124 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/42608a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/0447e43a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/50831da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2A) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104140000/104135000/104134950/9a31f88b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Lefevre By Wynwood House [](https://www.expedia.co.uk/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) Casco Viejo 9.2/10 Wonderful (7 reviews) "Staff was courteous, and the room was very beautiful. Would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Selam £127 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Las-Cumbres-Hotels-Casa-Lefevre-By-Wynwood-House.h104134950.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/93306cc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (24G) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f3c16015.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (40K) | Dining room](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/da16c1c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (24G) | Living room | Smart TV](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/74f146f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-By-Wynwood-House.h103606257.Hotel-Information) Calidonia 9.2/10 Wonderful (5 reviews) "I will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey £155 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-By-Wynwood-House.h103606257.Hotel-Information) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/118000000/117720000/117712800/117712723/223434f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/118000000/117720000/117712800/117712723/831bbade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/118000000/117720000/117712800/117712723/7720ab71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/118000000/117720000/117712800/117712723/f298302d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w Central 1BR in Vibrant Obarrio [](https://www.expedia.co.uk/Panama-City-Hotels-W-Central-1BR-In-Vibrant-Obarrio.h117712723.Hotel-Information) Bella Vista £122 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-W-Central-1BR-In-Vibrant-Obarrio.h117712723.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) Bella Vista 8.2/10 Very good (71 reviews) "Great location, wonderful views, spacious apartment, with comfortable bed and good ac. Amenities in the building are great too." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alan £166 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/4fefbf57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/34a0b683.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Apartment, 3 Bedrooms | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/c45dedaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.6/10 Good (173 reviews) "Clean room good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gideon £145 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/765b1a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) Casco Viejo 9.4/10 Exceptional (182 reviews) "Fabulous room and wonderful people that work there. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leah £114 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Apartment, 2 Bedrooms (1B) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/9e77777b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1D) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/3f9c0f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1A) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/4443ba1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1C) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/107000000/106100000/106093500/106093420/7717b8f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Love by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) Casco Viejo 9.0/10 Wonderful (24 reviews) "Large, clean rooms, lots of space. Great bathroom. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joette £95 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Casa-Love-By-Wynwood-House.h106093420.Hotel-Information) ![Apartment (3G) | Living area | 40-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/01dcce3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/9f5c2914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3K) | Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/035f9f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Apartment | Living area | 40-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/w2999h2000x0y0-8b973359.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuadra by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) El Chorrillo 9.0/10 Wonderful (50 reviews) "Superb customer service. Instant responsiveness. Almost miraculous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter £109 includes taxes & fees 11 Mar - 12 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/w3995h2667x0y0-2d9fa044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/0835e528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/640e3c80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Executive Apartments Panama City, Finisterre [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) Bella Vista 8.8/10 Excellent (697 reviews) "Enjoyed the stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Breneda £110 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=553248623287315690&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=VR_SPRING_PROMO_553248623287315690) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=APARTMENT) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=VILLA) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CONDO) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=COTTAGE) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=CABIN) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-06-08&d1=2026-06-08&endDate=2026-06-11&d2=2026-06-11&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Holiday-Rentals.d553248623287315690.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Holiday-Rentals.d553248623287315690.Travel-Guide-HolidayRentals) ## Top Santa Clara Hotel Reviews ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Pool area was restful.." [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 8/10 Good "Rooms were a bit outdated and maintained moisture making it constantly feel damp. Walls needed some cleaning and tending to. However the staff was excellent and very" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 8/10 Good "Hotel is in a great location for partying ans shopping " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 6/10 Okay "I could hear the traffic like I was standing outside The toilet keep running," [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "This hotel was amazingly beautiful I would choose to stay here again " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 8/10 Good "Best spot, everything is near and easy to get by." [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b_y.jpg) ### Marriott Panama Hotel 8/10 Good "Front staff were so helpful and friendly. " [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg) ### Sheraton Grand Panama 8/10 Good "Clean and comfortable room. Bathroom needs an overall. Faucets are hard to open and close." [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Ramada Plaza by Wyndham Panama Punta Pacifica](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b_y.jpg) ### Ramada Plaza by Wyndham Panama Punta Pacifica 10/10 Excellent "The room and the property is very clean. Excellent breakfast. Carlo at the front desk could be a little more pleasant. He seems to act as he is doing me a favor by checking me into the hotel. I guess because l’m a woman. I have been coming to this place since 2022 for at least 3 times a year and I hate when he is at the front desk. He seems to be more pleasant with men." [](https://expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ## Find out more about Santa Clara **Everything you need to know about** **Santa Clara** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Clara holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Clara holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Santa Clara holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Santa Clara. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Clara holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Santa Clara holiday rentals we have selected for you start as low as £66 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Santa Clara rentals** At Expedia, we put the best Santa Clara holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Santa Clara rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Clara holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Clara. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) ## Frequently asked questions ### Can I find holiday rentals in Santa Clara? ### What are some of the best holiday rentals that Santa Clara has to offer? ### What can I see and do in Santa Clara? ### What are holiday rentals like in Santa Clara? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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