Title: Cheap Car Hire in Santa Clara, PAN - Expedia.co.uk [Santa Clara Travel Guide](https://expedia.co.uk/Santa-Clara.dx553248623287315690)[Hotels in Santa Clara](https://expedia.co.uk/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Flights to Santa Clara](https://expedia.co.uk/Cheap-Flights-To-Santa-Clara.d553248623287315690.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.co.uk/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)[Santa Clara Holidays](https://expedia.co.uk/Santa-Clara.d553248623287315690.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santa Clara, PAN ## Search and Compare from Car Companies in Santa Clara ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santa Clara \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Santa Clara, Panamá Oeste Province, PAN ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Clara,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=553248623287315690&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Santa Clara, Panamá Oeste Province, PAN ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Clara,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=553248623287315690&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Santa Clara, Panamá Oeste Province, PAN ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Clara,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=553248623287315690&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Santa Clara, Panamá Oeste Province, PAN ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Clara,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=553248623287315690&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Santa Clara [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Clara,%20Panam%C3%A1%20Oeste%20Province,%20Panama&dpln=553248623287315690&date1=16/02/2026&date2=18/02/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Santa Clara? ### Can I hire a car from Tocumen Intl. Airport (PTY)? ### What happens if I need to cancel my Santa Clara car reservation? ### What types of cars can I rent in Santa Clara? ### Where can I go on a road trip from Santa Clara? > - Around 110 miles from Santa Clara, Santiago is a must-do for many road-trippers. With attractions like Parque Acuatico Italia Guadalupe Panama, you'll have no shortage of things to keep you busy here. > - Another destination popular with travellers is Penonome, around 55 miles away. 8 de Diciembre Park is just one of the many reasons people love this place. > - After all that driving, treat yourself to some time in nature at Red Frog Beach. It's approximately 170 miles from Santa Clara. ### How do I find the best car hire deals in Santa Clara with Expedia? ### What do you need to hire a car in Santa Clara? ### What is the cheapest car hire in Santa Clara? ### Can I hire a car for a month or longer in Santa Clara? ### Where can I find a Santa Clara hire car if I am younger than 25? ### Why should I rent a Santa Clara car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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