Santa Clara Holidays from £977

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Your Santa Clara Holiday

Art, food, entertainment and more … There's so much to experience with a Santa Clara holiday package. And with the ability to customise your city getaway, it's guaranteed to be one you won't forget. Eager to sightsee but not sure where to start? Any trip to Santa Clara should include Culebra Cut. Your dream Santa Clara holiday is a couple of clicks away. Search flights, accommodation and more on Expedia for a getaway that's tailored just for you.

Top Santa Clara Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Price was £1,330, price is now £977 per person
£977
per person
16 Oct - 23 Oct
found 24 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.4/10 Exceptional! (111 reviews)
The grounds where beautiful and the staff was so friendly.

Reviewed on 19 Jul 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was £3,177, price is now £1,964 per person
£1,964
per person
16 Oct - 23 Oct
found 24 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
No reviews
La Coralina Island House

La Coralina Island House

3.5 out of 5
Price was £1,706, price is now £1,243 per person
£1,243
per person
16 Oct - 23 Oct
found 24 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
9.4/10 Exceptional! (84 reviews)
Wow! This resort is absolutely amazing! Bekar went above and beyond for us! He even brought in a TV to the lobby so we could watch the NHL playoff game! Food is 10/10 as well. We will definitely go back!

Reviewed on 18 May 2025

NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
Price was £4,153, price is now £3,052 per person
£3,052
per person
16 Oct - 23 Oct
found 24 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
10/10 Exceptional! (54 reviews)
Amazing time across the board staying at both the Treehouse and the Ocean Villa for the week. The attention to the details made this an experience like no other. The treehouse created a one-of-a-kind experience especially with the views and birds around the island. Highly recommend doing both. The service staff were extremely kind and attentive to all needs with a caring spirit of service. The housekeeping staff kept the places immaculate each day. The food quality was exceptional, especially at dinner each night in the Elephant House. The focus and creativity of each meal along with the unique presentation each night really made it special. The soups and main course served each night were absoutely the best we have ever experienced. Our conpliments to the chefs. A special thanks to the staff that made us feel very special and exhibited the gift of hospitality. Outstanding service really shined through Gilberto, Andrea, Mikeal, Franco, Ruby, Carlos, Victor, Liz, Williams, Sherill, and so many others! If you desire an intimate, unique resort experience that you will never forget, this is your place!

Reviewed on 2 Aug 2025

Casa Fofo Family House

Casa Fofo Family House

3 out of 5
Price was £1,426, price is now £1,063 per person
£1,063
per person
16 Oct - 23 Oct
found 24 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
No reviews

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
1,400
Max Temp Winter
29ºC
Max Temp Summer
29ºC

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £82 per night from 27 Aug to 28 Aug
£82
27 Aug - 28 Aug
includes taxes & fees
9/10 Wonderful! (4,193 reviews)
Great stay
"This hotel gave me one of the most luxurious hotel experiences I’ve ever had. It is centrally located with easy access to all your daily social and business needs. The room was brilliantly designed to ensure for the customer luxury feel, comfort, convenience, and ample space. The staff were very ..."

Reviewed on 23 Aug 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is £164 per night from 16 Sept to 17 Sept
£164
16 Sept - 17 Sept
includes taxes & fees
7.2/10 Good! (1,008 reviews)
"The resort was amazing!!"

Reviewed on 24 Aug 2025

Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is £66 per night from 27 Aug to 28 Aug
£66
27 Aug - 28 Aug
includes taxes & fees
9/10 Wonderful! (430 reviews)
"Definitely an amazing hotel !! I will be back !!!"

Reviewed on 23 Aug 2025

Waymore Hotel Spa & Casino
See all 1,505 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Clara

Guided Jungle Adventure with Gatun Lake Cruise

Guided Jungle Adventure with Gatun Lake Cruise

£66
per adult
90% of travellers recommend
Guided Jungle Adventure with Gatun Lake Cruise
Gatun Lake boat ride

Panama Canal Monkey & Wildlife Boat Safari

£52
per adult
100% of travellers recommend
Panama Canal Monkey & Wildlife Boat Safari
Panama Canal Tour

Panama Canal Tour

£33
per adult
Panama Canal Tour
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara travel package cost?
Choose from any combination of flights, hotels and car rentals, and you can be holidaying in Santa Clara from just £977. And the more you bundle, the more money you save. Your dream escape has never been so affordable.
If I'm not able to travel, can I cancel my Santa Clara travel package?
Plans can change unexpectedly, so yes. You may be able to change or cancel your Santa Clara travel package for free within 24 hours of booking. For bookings older than that, you can still cancel or make changes, but your airline, hotel or car rental company may charge additional fees. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to Santa Clara?
It's easy. Just bundle. Flights, hotels and rental cars — combine whatever you need into a Santa Clara holiday package to save a pile of cash. Score even bigger bargains when you add extras such as activities or tours to your booking. But that's not the only good part. You have the flexibility to tailor your holiday your way. We offer over 550 air carriers and 1,000,000 properties across the world, so that everyone has a chance to travel and live out those holiday fantasies.
Does Expedia offer Book Now, Pay Later Santa Clara holidays?
Good news! We do. Expedia has partnered with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply select the payment plan best suited to your needs during the checkout process and take the stress out of budgeting for your trip. Don't forget to bundle your accommodation, flights and activities with Expedia to get the biggest bang for your buck. Browse our flexible payment options below:

  • Pay monthly holidays: If paying small amounts each month is what works best for you, Klarna offers just that! Paying in convenient monthly instalments will make that dream holiday possible.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday in multiple transactions.
  • Low deposit holidays: Pressing the "book now" button is much easier with this payment option. Just put down a small deposit on your holiday and then get on your way.

What are the top hotels in Santa Clara?
If this will be your first time in Santa Clara, book a room at The Westin Playa Bonita Panama or Dreams Playa Bonita Panama. Both will make you feel at home and are favourites with many savvy travellers.
How far in advance should I book my Santa Clara holiday?
Savvy travellers often book as early as possible. You can generally browse through international airfares on Expedia up to 12 months before your flight. If you're purchasing your ticket at the last minute, don't stress. Low prices occasionally become available in the last weeks before departure dates.
What does an Expedia Santa Clara travel package include?
Expedia has everything you need to organise your Santa Clara escape, but what your package looks like is your choice. Choose from a combination of flights, rental cars and hotels. Searching for a few activities to keep you on the move? Once you've made your booking, you can add them on too. No matter your style, there's a package deal to suit your needs.
What should I know before booking a Santa Clara travel package?
Booking all the parts of your holiday together is an excellent way to save. Bundle your car rentals, airfares and hotels into one little package. But your options don't end at hotels. Expedia has all types of properties, including holiday rentals such as beachside villas and spacious residences. You've got loads of choices!
Can I choose my airline with a Santa Clara Expedia travel package?
Yes, of course. We have more than 550 partner airlines across the globe, so opt for the carrier that best suits your budget and travel needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.