Santa Clara Holidays from £476

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Your Santa Clara Holiday

Art, food, entertainment and more … There's so much to experience with a Santa Clara holiday package. And with the ability to customise your city getaway, it's guaranteed to be one you won't forget. Eager to sightsee but not sure where to start? Any trip to Santa Clara should include Culebra Cut. Your dream Santa Clara holiday is a couple of clicks away. Search flights, accommodation and more on Expedia for a getaway that's tailored just for you.

Top Santa Clara Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was £703, price is now £476 per person
£476
per person
5 Jun - 8 Jun
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.2/10 Wonderful! (5 reviews)
Gréât location and the staff at the gate. Rom had everything except extra towells and cleaning liquids. Love to come again to stay in this property!

Reviewed on 8 Mar 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was £790, price is now £574 per person
£574
per person
4 Jun - 7 Jun
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.4/10 Very Good! (1,441 reviews)
The room are nice and clean the pool is too much noise. It’s a mess

Reviewed on 10 Mar 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was £957, price is now £697 per person
£697
per person
4 Jun - 7 Jun
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (1,010 reviews)
Fantastic location and hotel very good

Reviewed on 9 Mar 2026

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
Price was £1,261, price is now £971 per person
£971
per person
10 Apr - 14 Apr
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
7.6/10 Good! (1,006 reviews)
Rooms were a bit outdated and maintained moisture making it constantly feel damp. Walls needed some cleaning and tending to. However the staff was excellent and very

Reviewed on 9 Mar 2026

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

3 out of 5
San Francisco
Price was £1,265, price is now £979 per person
£979
per person
20 May - 27 May
found 4 hours ago
Return direct flight included
London (LON) to Panama City (PTY)
2.8/10 (3 reviews)

The Annual Holiday Sale

Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save.
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Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
1,400
Max Temp Winter
29ºC
Max Temp Summer
29ºC

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is £121 per night from 30 Mar to 31 Mar
£121
30 Mar - 31 Mar
includes taxes & fees
9/10 Wonderful! (5,094 reviews)
This hotel was amazingly beautiful I would choose to stay here again

Reviewed on 9 Mar 2026

Hotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £110 per night from 4 Apr to 5 Apr
£110
4 Apr - 5 Apr
includes taxes & fees
8.6/10 Excellent! (1,008 reviews)
Clean and comfortable room. Bathroom needs an overall. Faucets are hard to open and close.

Reviewed on 7 Mar 2026

Sheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
The price is £88 per night from 23 Mar to 24 Mar
£88
23 Mar - 24 Mar
includes taxes & fees
7.8/10 Good! (1,015 reviews)
Pool area was restful..

Reviewed on 9 Mar 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See all 1,594 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.