Title: Top 15 Hotels in Santa Clara for 2025 | Expedia.co.uk [Holiday Rentals in Santa Clara](https://expedia.co.uk/Santa-Clara-Holiday-Rentals.d553248623287315690.Travel-Guide-HolidayRentals)[Santa Clara Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Clara.d553248623287315690.Car-Hire-Guide)[Santa Clara Holidays](https://expedia.co.uk/Santa-Clara.d553248623287315690.Holidays-City-Breaks) ![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Clara from £17 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Clara Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=POOL) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=PETS) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=APARTMENT) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=OCEAN_VIEW) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&travelerType=family_friendly) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=CONDO) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama®ionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2025-12-03&d1=2025-12-03&endDate=2025-12-05&d2=2025-12-05&lodging=VILLA) ## Check prices for these dates Tonight [19 Nov - 20 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2025-11-19&endDate=2025-11-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Nov - 21 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248623287315690&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Santa Clara hotels and places to stay ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/174f9ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/w6390h4261x0y0-9ab7a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/58d3a2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo Casco Viejo 9.0/10 Wonderful (1002) "Hotel was beautiful, staff was very helpful and accommodating. We had the pool two separate days to ourselves. Breakfadt was very good. Staff was very helpful getting us drivers wherever we wanted to go in the city." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MICHELE [](https://www.expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/42ee64f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/dd414168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/de49bf58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 2 Double Beds | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/12f18f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Coral Suites Bella Vista 9.0/10 Wonderful (1002) "Great place for the price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan £58 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Coral-Suites.h3893051.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive House | Living area | 50-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/ed2f4dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![San Felipe Junior Suite, 1 Double bed or 2 Single Beds | 3 bedrooms, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/4964bad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/f174b378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Concordia Boutique Hotel Casco Viejo 9.6/10 Exceptional (192) "The staff was very friendly and supportive. The room was spectacular! It was beautifully decorated and very clean. It was just a delight to stay in this lovely hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Madelaine [](https://www.expedia.co.uk/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/8eab8913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/75931b67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/9a1e7717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds, Non Smoking | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/7b4ef00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1003) "Very beautiful room was spotless, and staff was very good with customer service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony £143 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/49ac0a05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/86d63ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/c95dd32a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 2 Double Beds, Non Smoking (TRYP) | 1 bedroom, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/e150b6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Panamá Centro Bella Vista 9.2/10 Wonderful (1009) "Staff was helpful, room was clean and I enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lystra £64 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-TRYP-By-Wyndham-Panama-Centro.h5309170.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/ea26a97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino Tocumen 8.6/10 Excellent (1888) "I love the included shuttle and breakfast and how close it is to the airport" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) leon £105 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/0d6dbc5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/be207e74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/daf15c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve Colon 7.8/10 Good (654) "We had a lovely stay, the views and tranquility of the place was my favorite part." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca £84 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/b119cb62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/a2ab1d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/d813f542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Panama City Bella Vista 9.2/10 Wonderful (1006) "Room very clean, nice staffs and good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hayden £76 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/cecfcd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/d3127913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/31f2cc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Principe Hotel and Suites Bella Vista 9.0/10 Wonderful (1555) "A nice hotel with plenty of shopping and restaurants in the area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neil £42 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/1875cd38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 12 per person)](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/533863fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/1e34413a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/11000000/10420000/10412900/10412883/deeb0964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Panama Centro Via Argentina Bella Vista 7.4/10 Good (264) "Hotel staff and rooms were good , great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cornelly £50 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Panama-Centro-Via-Argentina.h10412883.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/b594ef85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Bella Vista 9.2/10 Wonderful (1006) "great stay when in PTY" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando £148 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/7c4bef31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/db8dd960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/14f91618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/73e2776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospedium Princess Hotel Panama Bella Vista 7.6/10 Good (677) "The breakfast was great, I love the pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Estefani £46 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/4a3f7176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/a87f2f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/7d818005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Panama San Francisco 8.6/10 Excellent (880) "Great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RENE £98 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (629) "Beautiful property. Excellent lunch, fish tacos were amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc £181 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/w3989h2656x0y8-13f5112b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/9d48c90f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/cd4ab84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/c67d7481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall Cerro Viento 8.8/10 Excellent (1008) "It was very clean good friendly staff good food i really love there goong back next time " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sylvester Keith £88 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/02cb9f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Courtyard View | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/6a2573d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/4bc8c674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/f5a76e37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compañía Casco Antiguo Casco Viejo 9.8/10 Exceptional (245) "Many shops and restaurants nearby and the hotel is located in a beautiful area " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry £305 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-La-Compania.h71135966.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/3bea3d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/fd24a6ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe Casco Viejo 9.4/10 Exceptional (231) "Really nice staff and property is in amazing location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £102 includes taxes & fees 24 Nov - 25 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Daily cooked-to-order breakfast (USD 15.00 per person)](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed with Sofa bed, Non Smoking, City View | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/5c25de94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/6407170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/6d66fb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Multiplaza Mall San Francisco 8.8/10 Excellent (1001) "Perfect stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) pedro £102 includes taxes & fees 6 Dec - 7 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![2 restaurants, local cuisine](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Supreme Suite, 1 King, Partial City view, Corner room | In-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/d1c75b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/7a936012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse I, Suite, 1 King, Partial City view | Living room | LCD TV, iPod dock](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/c594bc6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W Panama Bella Vista 9.0/10 Wonderful (1002) "Clean room, great views, great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley £160 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/aaf98ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/283a5f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/f264b2cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7060000/7057300/7057295/3b29d54b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton by Hilton Panama Bella Vista 7.8/10 Good (1001) "The hotel is good for the price , the lobby didn’t have any air conditioning,also the rooms where clean but needed to be updated , the breakfast buffet had multiple choices and it was very good . The hotel is in great location near walking distance to restaurants and stores . I will stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yusneilys amores £60 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Hampton-By-Hilton-Panama.h7057295.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05®ionId=553248623287315690&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels) ## Stay near popular Santa Clara attractions [](https://www.expedia.co.uk/Culebra-Cut-Hotels.0-l6078511-0.Travel-Guide-Filter-Hotels) ### Culebra Cut You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6078511) ## Learn more about Santa Clara Santa Clara awaits: its natural setting, monuments, history and more! [See all hotels in Santa Clara](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05&adults=2®ionId=553248623287315690) ![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=900&h=450&p=1&q=high) ## Top Santa Clara Hotel Reviews ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Room and the facility were exceptionally clean and well maintained. All of the staff was extremely helpful and friendly. Especial thank to bar staff in the main lobby and the master of ceremonies." [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Decent place to stay. Convenient and welcoming staff" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "We stay at this hotel at least 3 times per year! The staff is great! The food is great! And the room is very comfortable! The location is great and close to the metro." [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "yes" [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "Great Hotel. The room was really big and confortable. Breakfast with a lot of options. Very clean hotel. Great staff." [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Food variety and freshness " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "The room was spotless and the staff was courteous " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg) ### Arcadia Condo Suites 10/10 Excellent "Excellent appartement " [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Yes" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ## More cheap stays in Santa Clara ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province £104 22 Nov - 23 Nov includes taxes & fees 9.2/10 Wonderful! (131 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Magnolia Inn](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Inn 8-18 Calle 8 y Calle Boquete Panama City Panama £54 21 Nov - 22 Nov includes taxes & fees 8.8/10 Excellent! (395 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Panama House Bed & Breakfast](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/0f765b96_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panama House Bed & Breakfast Calle 1era El Carmen- Casa # 32 Panama City £27 21 Nov - 22 Nov includes taxes & fees 8.8/10 Excellent! (179 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Viajero Casco Viejo Hostel](https://images.trvl-media.com/lodging/119000000/118800000/118790900/118790803/2c436ca6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Viajero Casco Viejo Hostel Avenida B, Calle 12 Este, Casco Viejo Panama City £27 26 Nov - 27 Nov includes taxes & fees 6.6/10 (4 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Viajero-Casco-Viejo-Hostel.h118790803.Hotel-Information) ![Hotel República](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel República Plaza 5 De Mayo Final Ave Panama City Panama [Get rates](https://expedia.co.uk/Hotel-Search?startDate=04%2F12%2F2025&endDate=05%2F12%2F2025&selected=3257592&PinnedHotelID=3257592&HadPinnedHotel=true®ionId=553248623287315690) 6.4/10 (179 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Panamá Experience Hostel](https://images.trvl-media.com/lodging/98000000/97460000/97450400/97450315/d506ce19_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panamá Experience Hostel Calle 54 Este Panama City Provincia de Panamá £17 23 Nov - 24 Nov includes taxes & fees 7.2/10 Good! (33 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Panama.h97450315.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Santa Clara? > The most popular time to visit Santa Clara is January, when the city comes alive with a vibrant atmosphere and a variety of events. During this peak season, which runs from January to March, temperatures are pleasantly warm, averaging around 25°C. This delightful climate is great for exploring the city's rich history and enjoying outdoor activities. > > > > While January is bustling with tourists, it also offers a unique opportunity to immerse yourself in the local culture. Many festivals and celebrations take place during this time, allowing you to experience the heart of Santa Clara's vibrant community. You can wander through the city's lively streets, visit historic sites such as the Che Guevara Mausoleum, or relax in one of the many charming parks. > > > > For those seeking a quieter experience or perhaps a more budget-friendly option, May is an excellent time to consider. The prices are generally lower, yet you can still enjoy the warm temperatures and beautiful scenery. This month allows for a more relaxed pace, great for leisurely sightseeing and enjoying the local cuisine without the hustle and bustle of peak tourist season. ### Where can I find the best nightlife in Santa Clara? > Santa Clara is a charming beachside destination that offers a laid-back atmosphere, great for those looking to unwind after a day in the sun. > > > > While the nightlife in Santa Clara is not as vibrant as in larger cities, there are still some delightful spots where you can enjoy a relaxed evening. The beachfront area features a few bars and restaurants that often host live music and events, creating a friendly and inclusive setting. > > > > For a more lively experience, many visitors choose to venture to nearby Coronado, where you can find a variety of bars and clubs that cater to different tastes. The bustling streets of Coronado come alive in the evenings, offering both local and international flavours, making it a great option for a night out. > > > > If you're looking for a quieter night, consider enjoying a sunset at one of the beachfront restaurants in Santa Clara, where you can sip on cocktails while taking in the stunning views. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Clara hotel for you. ### How can I save on a Santa Clara hotel booking with Expedia? > Before booking your Santa Clara hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Santa Clara hotel? > Prices for hotels in Santa Clara often vary, but you can find a great deal from £17 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [1 Star Hotels in Barro Colorado Island](https://www.expedia.co.uk/1Star-Barro-Colorado-Island-Hotels.s10-0-d6078515.Travel-Guide-Filter-Hotels) - [Barro Colorado Island Hotels](https://www.expedia.co.uk/Barro-Colorado-Island-Hotels.d6078515.Travel-Guide-Hotels) - [Campana Hotels](https://www.expedia.co.uk/Campana-Hotels.d553248635996709309.Travel-Guide-Hotels) - [Capira Hotels](https://www.expedia.co.uk/Capira-Hotels.d3000431337.Travel-Guide-Hotels) - [Panamá Oeste Province Hotels](https://www.expedia.co.uk/Destinations-In-Panama-Oeste-Province.d553248635975177201.Hotel-Destinations) - [Guadalupe Hotels](https://www.expedia.co.uk/Guadalupe-Hotels.d3000423195.Travel-Guide-Hotels) - [La Chorrera Hotels](https://www.expedia.co.uk/La-Chorrera-Hotels.d3000476724.Travel-Guide-Hotels) - 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