Title: Santa Clara Travel Guide: Best of Santa Clara, Panamá Oeste Province Travel 2026 | Expedia.co.uk [Hotels in Santa Clara](https://expedia.co.uk/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Holiday Rentals in Santa Clara](https://expedia.co.uk/Santa-Clara-Holiday-Rentals.d553248623287315690.Travel-Guide-HolidayRentals)[Santa Clara Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Clara.d553248623287315690.Car-Hire-Guide)[Santa Clara Holidays](https://expedia.co.uk/Santa-Clara.d553248623287315690.Holidays-City-Breaks) # Santa Clara Travel Guide ## Tourist Guide ![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Clara Things to do - Top hotels in Santa Clara - Top Holiday Rentals in Santa Clara ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/6f5f0f4f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Riu Plaza Panama Calle 50, Urb. Marbella Panama City Panama £121 5 May - 6 May includes taxes & fees Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ... 9/10 Wonderful! (5,216 reviews) Breakfast was really good 5 stars only negative was the pool bar and face cloths. Other than that property is beyond nice Reviewed on 5 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F05%2F2026&endDate=06%2F05%2F2026&selected=3900395&PinnedHotelID=3900395&HadPinnedHotel=true®ionId=553248623287315690) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/4e948961_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Grand Panama Via Israel And 77th Street Panama City Panama £117 29 Apr - 30 Apr includes taxes & fees Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ... 8.6/10 Excellent! (1,007 reviews) Everything was great, really nice stay Reviewed on 6 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F04%2F2026&endDate=30%2F04%2F2026&selected=1161&PinnedHotelID=1161&HadPinnedHotel=true®ionId=553248623287315690) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### W Panama Calle Aquilino de la Guardia & Calle 50 Panama City £249 2 May - 3 May includes taxes & fees Stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ... 8.8/10 Excellent! (1,009 reviews) Didn’t have room for me Reviewed on 5 Apr 2026 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F05%2F2026&endDate=03%2F05%2F2026&selected=21314035&PinnedHotelID=21314035&HadPinnedHotel=true®ionId=553248623287315690) [See all 1,352 properties in Santa Clara](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=07%2F04%2F2026&endDate=08%2F04%2F2026®ionId=553248623287315690) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province Stay at this aparthotel in Panama City. Enjoy free Wi-Fi, free parking and a rooftop terrace. Popular attractions Multiplaza Pacific Mall and Avenida Balboa ... 9.4/10 Exceptional! (258 reviews) Amazing building . High end . Smelled wonderful . Pool was beautiful Reviewed on 4 Apr 2026 [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Marriott Executive Apartments Panama City, Finisterre](https://images.trvl-media.com/lodging/5000000/4960000/4959000/4958983/b4d43ebd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Marriott Executive Apartments Panama City, Finisterre Calle Colombia Y Ave.,3ra A Sur, Bella V Panama City Panama Stay at this business-friendly aparthotel in Panama City. Enjoy free Wi-Fi, free parking and 2 bars/lounges. Our guests praise the helpful staff in their reviews. ... 8.8/10 Excellent! (708 reviews) Jonathan at the front desk was the best of the best. When i visit again I will stay in that hotel again! 20/10 experience! Reviewed on 5 Apr 2026 [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Executive-Apartments-Panama-City.h4958983.Hotel-Information) ![Torres de Alba Hotel & Suites](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Torres de Alba Hotel & Suites Calle Eusebio A. Morales y Calle 55 Panama City Panama Stay at this business-friendly aparthotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ... 8.8/10 Excellent! (538 reviews) Simply The Best!!! Reviewed on 4 Apr 2026 [](https://expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) [See all properties in Santa Clara](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248623287315690&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Clara hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=2026-04-06&endDate=2026-04-07)[6 Apr - 7 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=2026-04-06&endDate=2026-04-07) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=2026-04-07&endDate=2026-04-08)[7 Apr - 8 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=2026-04-07&endDate=2026-04-08) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026)[10 Apr - 12 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=10%2F04%2F2026&endDate=12%2F04%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=17%2F04%2F2026&endDate=19%2F04%2F2026)[17 Apr - 19 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248623287315690&startDate=17%2F04%2F2026&endDate=19%2F04%2F2026) ### Popular places to visit #### Culebra Cut You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area. [](https://expedia.co.uk/Culebra-Cut-Santa-Clara.d6078511.Attraction) ### Things to do ![Panama Canal Tour: Miraflores Locks & IMAX Movie - Afternoon](https://mediaim.expedia.com/localexpert/46138380/233a3b35-9fba-421f-b566-37669f374b9d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panama Canal Tour: Miraflores Locks & IMAX Movie - Afternoon £26 per adult [](https://expedia.co.uk/things-to-do/panama-canal-tour-miraflores-locks-imax-movie-afternoon.a46138380.activity-details) ![Gatun Lake boat ride](https://mediaim.expedia.com/localexpert/1017210/ca9be5c8-beac-43c1-a9eb-066feb136f76.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Monkey & Sloth Panama Canal Boat Safari with Casco Viejo Brunch £45 per adult **98%** of travellers recommend [](https://expedia.co.uk/things-to-do/monkey-sloth-panama-canal-boat-safari-with-casco-viejo-brunch.a1017210.activity-details) ![Monkey and Sloth Jungle Habitat Panama Tour ](https://mediaim.expedia.com/localexpert/47313144/f3dd1c31-b1f2-41ca-8793-3abcbc166e9d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Monkey and Sloth Jungle Habitat Panama Tour £27 per adult **98%** of travellers recommend [](https://expedia.co.uk/things-to-do/monkey-and-sloth-jungle-habitat-panama-tour.a47313144.activity-details) ![MiraLift](https://mediaim.expedia.com/localexpert/1116180/4f40785f-2369-4d7c-83f7-b0a5cc7ac401.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Transfer to Panama Canal (Miraflores Locks) £10 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/transfer-to-panama-canal-miraflores-locks.a1116180.activity-details) ![Panamá Canal and Old Town ](https://mediaim.expedia.com/localexpert/46047029/ccc0ec72-b8fd-4f79-8557-c566cdac448f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Panamá Canal and Old Town £60 per adult [](https://expedia.co.uk/things-to-do/panama-canal-and-old-town.a46047029.activity-details) ![5hour tour of Panama City and Panama Canal - Shared or Private](https://mediaim.expedia.com/localexpert/46748153/ce7bc0f4-84a1-4ec1-9f86-afb5aaceebb9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 5hour tour of Panama City and Panama Canal - Shared or Private £49 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/5hour-tour-of-panama-city-and-panama-canal-shared-or-private.a46748153.activity-details) [See all activities in Santa Clara](https://expedia.co.uk/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities) ## Cities near Santa Clara ![default](https://images.trvl-media.com/place/2897/9a0fe9cb-10b8-4a85-b416-4677f1455ea0.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Panama City - Cities near Santa Clara - Places of interest [Panama City](https://expedia.co.uk/Panama-City.dx2897) - [Albrook Shopping Mall ](https://expedia.co.uk/Albrook-Shopping-Mall-Panama-City.d6159851.Attraction) - [Cinta Costera ](https://expedia.co.uk/Cinta-Costera-Calidonia.d6245970.Attraction) - [Colon Free Zone ](https://expedia.co.uk/Colon-Free-Zone-Barrio-Sur.d6078503.Attraction) - [Fuerte Amador Resort & Marina ](https://expedia.co.uk/Fuerte-Amador-Resort-Marina-Amador.d553248621532964846.Attraction) - [Gamboa Rainforest Resort ](https://expedia.co.uk/Gamboa-Rainforest-Resort-Colon.d6078513.Attraction) - [Metropolitan Cathedral of Panama ](https://expedia.co.uk/Metropolitan-Cathedral-Of-Panama-Casco-Viejo.d6078477.Attraction) - [Panama Canal Railway ](https://expedia.co.uk/Panama-Canal-Railway-Panama-City.d553248621532619522.Attraction) - [Pacific Center ](https://expedia.co.uk/Pacific-Center-San-Francisco.d633625826652135424.Attraction) - [Bridge of the Americas ](https://expedia.co.uk/Bridge-Of-The-Americas-Arraijan.d6078487.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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