Title: Panacea Holiday Homes from £177: Search Holiday Homes in Panacea | Expedia.co.uk [Panacea Travel Guide](https://expedia.co.uk/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.co.uk/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Holiday Rentals in Panacea](https://expedia.co.uk/Panacea-Holiday-Rentals.d3000431554.Travel-Guide-HolidayRentals)[Panacea Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panacea.d3000431554.Car-Hire-Guide)[Panacea Holidays](https://expedia.co.uk/Panacea.d3000431554.Holidays-City-Breaks) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [17 Jul - 19 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=3000431554&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panacea holiday homes ![Beach nearby, sun-loungers](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/1674545d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/7710be2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/90-cb6090de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/90-642a3a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded Florida Beach Bungalow FEBRUARY SPECIAL $2000 FOR THE MONTH!! [](https://www.expedia.co.uk/Panacea-Hotels-The-Spotted-Grouper-Old-Florida-Beach-Bungalow.h48526748.Hotel-Information) Panacea 10/10 Exceptional (247 reviews) "2nd time staying here and it was so beautiful we will definitely be back, everything was wonderful and the host was amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carrie J. £291 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Panacea-Hotels-The-Spotted-Grouper-Old-Florida-Beach-Bungalow.h48526748.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/ccee74a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/07b6fb25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/09177221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115460000/115458600/115458502/e0212a42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW - St. Teresa Beach Escape w/ Private Beach Acc [](https://www.expedia.co.uk/Panacea-Hotels-NEW-St-Teresa-Beach-Escape-W-Private-Beach-Acc.h115458502.Hotel-Information) Lanark Village £379 includes taxes & fees 28 Mar - 29 Mar [](https://www.expedia.co.uk/Panacea-Hotels-NEW-St-Teresa-Beach-Escape-W-Private-Beach-Acc.h115458502.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/127000000/126360000/126359400/126359315/084a0dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/127000000/126360000/126359400/126359315/w1917h1080x1y0-accc7ddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/127000000/126360000/126359400/126359315/b570c91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/127000000/126360000/126359400/126359315/35fa330e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fisherman's Retreat Entire home in Panacea, Florida [](https://www.expedia.co.uk/Panacea-Hotels-Fishermans-Retreat-Entire-Home-In-Panacea.h126359315.Hotel-Information) Panacea £214 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Panacea-Hotels-Fishermans-Retreat-Entire-Home-In-Panacea.h126359315.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/52000000/51880000/51876700/51876637/81744a78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/52000000/51880000/51876700/51876637/65a7bfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, printers](https://images.trvl-media.com/lodging/52000000/51880000/51876700/51876637/c5dacbde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel cot, WiFi](https://images.trvl-media.com/lodging/52000000/51880000/51876700/51876637/46241804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock [](https://www.expedia.co.uk/Panacea-Hotels-Skipper-Extends-From-Beach-Front-To-Harbor-With-Kayaks.h51876637.Hotel-Information) Panacea 9.8/10 Exceptional (96 reviews) "We really enjoyed our time at Skipper! It's location on the west end of Alligator Point is perfect for walking the beach for miles in either direction. With so many shells to search for and so many dolphins to watch, our time there was so relaxing that we can't wait to go back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen R. £356 includes taxes & fees 17 Apr - 18 Apr [](https://www.expedia.co.uk/Panacea-Hotels-Skipper-Extends-From-Beach-Front-To-Harbor-With-Kayaks.h51876637.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96760000/96752500/96752463/509a1cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96760000/96752500/96752463/c4640e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96760000/96752500/96752463/ff0403f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96760000/96752500/96752463/f9546f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Beach Nest - A Peaceful Paradise! [](https://www.expedia.co.uk/Panacea-Hotels-The-Beach-Nest-A-Newly-Renovated-Paradise.h96752463.Hotel-Information) Alligator Point 9.8/10 Exceptional (28 reviews) "Very peaceful and relaxing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becca R. £332 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/Panacea-Hotels-The-Beach-Nest-A-Newly-Renovated-Paradise.h96752463.Hotel-Information) ![Sun-loungers, beach towels](https://images.trvl-media.com/lodging/113000000/112440000/112431800/112431789/10edec72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/113000000/112440000/112431800/112431789/9a9333da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112440000/112431800/112431789/f465e87b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112440000/112431800/112431789/24f01195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3BR, 2BA Beach Front Peaceful Retreat Recently Renovated with Private Boardwalk [](https://www.expedia.co.uk/Panacea-Hotels-3BR.h112431789.Hotel-Information) Alligator Point 9.8/10 Exceptional (8 reviews) "Great screen porch and comfortable beds!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Traci A. [](https://www.expedia.co.uk/Panacea-Hotels-3BR.h112431789.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/a1fd53d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/6a1354bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/b2492e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/117000000/116790000/116784100/116784001/20ef87c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Beach & Dock - Quiet Waterfront Retreat on Ochlockonee Bay [](https://www.expedia.co.uk/Panacea-Hotels-Private-Beach-Dock-Quiet-Waterfront-Retreat-On-Ochlockonee-Bay.h116784001.Hotel-Information) Panacea 10/10 Exceptional (1 review) "host and the peace and ouietness of the area great for relaxing with out all of the giltter and gallyer" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) william C. £363 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Panacea-Hotels-Private-Beach-Dock-Quiet-Waterfront-Retreat-On-Ochlockonee-Bay.h116784001.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/29b9886d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun-loungers, beach towels](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/713cab07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/97a88bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120270500/120270445/9e91ad83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Point & Paddle Waterfront Retreat @Alligator Point [](https://www.expedia.co.uk/Panacea-Hotels-Alligator-Point-Paddle-Pond-Home-Short-Walk-To-The-Beach.h120270445.Hotel-Information) Alligator Point 10/10 Exceptional (1 review) "Not only is this house adorable and roomy, it is the perfect mix of secluded and convenient. I hosted my girls for a little weekend birthday celebration and we had the best time watching the sunset from the dock, then enjoying a bonfire with smores! We played games and laughed well in to the night before finally retiring to the super comfy beds. The next morning we took the short walk to the beach and enjoyed discovering all types of nature while walking through the beaches of bald point state... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Holley C. £419 includes taxes & fees 27 Apr - 28 Apr [](https://www.expedia.co.uk/Panacea-Hotels-Alligator-Point-Paddle-Pond-Home-Short-Walk-To-The-Beach.h120270445.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/da44be87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/8fcbe9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, table football](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/6ddf58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/9af5aa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front [](https://www.expedia.co.uk/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information) Alligator Point 10/10 Exceptional (124 reviews) "Love this house! Plenty of beds, great views and the house was stocked as well as I’ve ever seen in a rental property (I’m serious!!!). Thank you!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott G. £1,663 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016286/9ac172c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016286/ac6d2aeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016286/f7c93cc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016286/701fe996.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Oyster Bed- Riverwalk Cottages Unit 204 B [](https://www.expedia.co.uk/Carrabelle-Hotels-House.h68016286.Hotel-Information) Carrabelle 9.8/10 Exceptional (45 reviews) "Annual girls trip!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan H. £177 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Carrabelle-Hotels-House.h68016286.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/69000000/68300000/68296100/68296092/a6afebf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/69000000/68300000/68296100/68296092/d22b075f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68300000/68296100/68296092/0dc5dcdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68300000/68296100/68296092/c15105f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront -Beautiful sunsets, great fishing, scalloping & bird watching [](https://www.expedia.co.uk/Tallahassee-Hotels-Brand-New-Listing-In-Oyster-Bay.h68296092.Hotel-Information) Crawfordville 10/10 Exceptional (51 reviews) "Great place for a weekend getaway " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £225 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Tallahassee-Hotels-Brand-New-Listing-In-Oyster-Bay.h68296092.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/108000000/107300000/107292300/107292244/w1015h762x0y0-13c02646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/108000000/107300000/107292300/107292244/w1125h843x0y1-f18e780d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/108000000/107300000/107292300/107292244/f694430c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/108000000/107300000/107292300/107292244/2c2ad209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dragonfly on the Canal [](https://www.expedia.co.uk/Crawfordville-Hotels-Dragonfly-On-The-Canal.h107292244.Hotel-Information) Crawfordville 10/10 Exceptional (36 reviews) "Very clean and spacious for lots of guests!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caitlin P. £244 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Crawfordville-Hotels-Dragonfly-On-The-Canal.h107292244.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016287/ea2aea2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016287/f070e364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016287/7ca7e48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016287/1186af93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sand Dollar - Riverwalk Cottages Unit 204 A [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Sand-Dollar-Riverwalk-Cottages-Unit-204-A.h68016287.Hotel-Information) Carrabelle 10/10 Exceptional (28 reviews) "It was convenient to the wedding venue, restaurants and gas station. Kelly was the best. So helpful in every way. Would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela A. £178 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Sand-Dollar-Riverwalk-Cottages-Unit-204-A.h68016287.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/114000000/113660000/113653600/113653580/dab79178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/114000000/113660000/113653600/113653580/a4e6c824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/114000000/113660000/113653600/113653580/b2f74efe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/114000000/113660000/113653600/113653580/bd9097dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centrally Located Charming 3 Bed 2.5 Bath Townhome with King Bed [](https://www.expedia.co.uk/Crawfordville-Hotels-Centrally-Located-Charming-3-Bed-25-Bath-Townhome-With-King-Bed.h113653580.Hotel-Information) Crawfordville £342 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Crawfordville-Hotels-Centrally-Located-Charming-3-Bed-25-Bath-Townhome-With-King-Bed.h113653580.Hotel-Information) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016284/3872bef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016284/0d641a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016284/f34c23a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68020000/68016300/68016284/213ab5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blue Crab at Riverwalk Cottages Unit 202B [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Blue-Crab-At-Riverwalk-Cottages-Unit-202b.h68016284.Hotel-Information) Carrabelle 9.6/10 Exceptional (14 reviews) "Great rental! Clean and plenty of room to park the boat " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erin G. £178 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Carrabelle-Hotels-The-Blue-Crab-At-Riverwalk-Cottages-Unit-202b.h68016284.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=3000431554&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=VACATION_HOME) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CABIN) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=CONDO) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=COTTAGE) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=VILLA) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-06-25&d1=2026-06-25&endDate=2026-06-28&d2=2026-06-28&lodging=APARTMENT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Private-Holiday-Homes.d3000431554-aaPrivateHolidayHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Private-Holiday-Homes.d3000431554-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Top Panacea Hotel Reviews ![Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations](https://images.trvl-media.com/lodging/116000000/115690000/115681700/115681652/908f3d2c_y.jpg) ### Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations 10/10 Excellent "The location of the house was perfect. Beautiful views!" [](https://expedia.co.uk/Panacea-Hotels-Gulf-Breeze-Pet-Friendly-3BR-Beachfront-Stay-With-Stunning-Views-Renovations.h115681652.Hotel-Information) ![Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis](https://images.trvl-media.com/lodging/123000000/122930000/122925400/122925353/6bf09396_y.jpg) ### Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis 10/10 Excellent "This place was perfect!!!! Host was amazing, super clean and so so so cute!! We can't wait to come back and stay again!" [](https://expedia.co.uk/Panacea-Hotels-Gorgeous-WaterfrontHot-TubPoolGolf-CartKayaksFishingTennisPickle-Ball.h122925353.Hotel-Information) ![ Secluded Florida Beach Bungalow FEBRUARY SPECIAL $2000 FOR THE MONTH!!](https://images.trvl-media.com/lodging/49000000/48530000/48526800/48526748/1674545d_y.jpg) ### Secluded Florida Beach Bungalow FEBRUARY SPECIAL $2000 FOR THE MONTH!! 8/10 Good "Loved the cottage. Only drawback is the seclusion. I’m sure in the busy season things are livelier. But we were looking for quiet and that’s what we got!" [](https://expedia.co.uk/Panacea-Hotels-The-Spotted-Grouper-Old-Florida-Beach-Bungalow.h48526748.Hotel-Information) ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/7ddc9d09_y.jpg) ### The Panacea Motel 8/10 Good "Parking was easy, right outside the room. The room was tiny but wonderful and really nice for what it was. AC kept the room comfortable and is extremely quiet. Great communication from the staff about the only issue with the tv but beyond their control. Definitely will book again when we go back to Panacea. " [](https://expedia.co.uk/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Gorgeous Ocean Views in Modern Beachfront Home](https://images.trvl-media.com/lodging/83000000/82940000/82939000/82938909/bee39842_y.jpg) ### Gorgeous Ocean Views in Modern Beachfront Home 10/10 Excellent "What a great place to stay. Clean. Right on the beach. " [](https://expedia.co.uk/Panacea-Hotels-Gorgeous-Ocean-Views-In-Modern-Beachfront-Home.h82938909.Hotel-Information) ![Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +](https://images.trvl-media.com/lodging/108000000/107290000/107284100/107284077/5342dafe_y.jpg) ### Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes + 8/10 Good "This is a beautiful place and the beach is right out the door! The sunrise views were amazing. We enjoyed walking the beach to looks for shells, surf fishing, and watching the dolphins. The hot tub was great to relax in, especially with the cooler temperatures during our stay. The deck was fantastic to hang out on, though the baby gates made it difficult to get up and down carrying luggage. These would be great for those with pets or small kids, but that wasn't our case. We enjoyed the golf cart use before it broke, and was out for repairs the rest of our trip, we had a great time just cruising on the golf cart. The floors inside the house appear to have had water damage, totally understandable on the beach in Florida, but we did have our feet pinched a few times when the planks would move. Overall we had a great and relaxing trip and would definitely stay again! " [](https://expedia.co.uk/Panacea-Hotels-Private-Beachfront-W-Golf-Cart.h107284077.Hotel-Information) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/da44be87_y.jpg) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front 10/10 Excellent "Beautiful house with awesome views of the gulf and the bay from all rooms. Fenced in yard was perfect for our dog. Location is very relaxing. I can't wait to go back." [](https://expedia.co.uk/Panacea-Hotels-7-Bedroom-Beach-House-With-POOL-Gulf-Front-And-Bay-Front.h19008298.Hotel-Information) ![Best deal at Alligator Point](https://images.trvl-media.com/lodging/34000000/33490000/33486800/33486730/f2e6bb56_y.jpg) ### Best deal at Alligator Point 8/10 Good "A clean and well equipped home. Great waterfront view. We were greeted by lady host, we were told owner was right next door, feel free to stop by with questions, or issues. When Wifi didn't connect, I walked over to get suggestions on getting a connection, and was chewed out for disturbing him???? " [](https://expedia.co.uk/Panacea-Hotels-Best-Deal-At-Alligator-Point.h33486730.Hotel-Information) ![PRIVATE LUXURY BEACHFRONT HOME!](https://images.trvl-media.com/lodging/56000000/55370000/55361200/55361115/6cd29c9b_y.jpg) ### PRIVATE LUXURY BEACHFRONT HOME! 10/10 Excellent "We had a great time, the place was wonderful and had everything we needed right there for us. We would come again!" [](https://expedia.co.uk/Panacea-Hotels-NEW-5-Bedroom-5-Bathroom-Beachfront-Home-With-Views-From-Every-Room.h55361115.Hotel-Information) ## Find out more about Panacea ## Panacea Holiday Homes information | Number of reviews | 679 | | ----------------- | ----------------- | | Accommodation | 221 Holiday Homes | | Lowest Price | £177 | | Highest Price | £1,663 | ## Explore a world of travel with Expedia - More ways to book - [Book Holiday Homes in Panacea on Expedia.com ](https://www.expedia.com/Panacea-Private-Vacation-Homes.d3000431554-aaPrivateVacationHomes.Travel-Guide-Accommodation)