Title: TOP Luxury Hotels in Northwest San Antonio, TX for 2026 - Northwest San Antonio Upscale Hotels | Expedia.co.uk [Northwest San Antonio Travel Guide](https://expedia.co.uk/Northwest-San-Antonio.dx6059170)[Hotels in Northwest San Antonio](https://expedia.co.uk/Northwest-San-Antonio-Hotels.d6059170.Travel-Guide-Hotels)[Holiday Rentals in Northwest San Antonio](https://expedia.co.uk/Northwest-San-Antonio-Holiday-Rentals.d6059170.Travel-Guide-HolidayRentals)[Flights to Northwest San Antonio](https://expedia.co.uk/Cheap-Flights-To-Northwest-San-Antonio.d6059170.Travel-Guide-Flights)[Things to do in Northwest San Antonio](https://expedia.co.uk/Things-To-Do-In-Northwest-San-Antonio.d6059170.Travel-Guide-Activities)[Northwest San Antonio Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Northwest-San-Antonio.d6059170.Car-Hire-Guide)[Northwest San Antonio Holidays](https://expedia.co.uk/Northwest-San-Antonio.d6059170.Holidays-City-Breaks) ![Roller Coaster](https://images.trvl-media.com/place/502602/9aaf48be-94fb-4cf1-b3fd-b5ed3097ae79.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/502602/9aaf48be-94fb-4cf1-b3fd-b5ed3097ae79.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Northwest San Antonio Luxury Hotels Tonight [13 Mar - 14 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059170&startDate=2026-03-13&endDate=2026-03-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [14 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059170&startDate=2026-03-14&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059170&startDate=2026-03-13&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6059170&startDate=2026-03-20&endDate=2026-03-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Northwest San Antonio luxury hotels ![Lobby](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/d38f20a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 2 outdoor pools, pool cabanas (surcharge), pool loungers](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/8185b422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/541a4b9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/949ee0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort [](https://www.expedia.co.uk/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) La Cantera District 8.4/10 Very good (1,000 reviews) "Great location, very clean and nice facilities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £136 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) ![5 outdoor pools, a heated pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2556x0y4-935acc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2555x3y3-735de940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2559x3y3-1eaafa8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3837h2549x3y3-a19f857c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Signia by Hilton La Cantera Resort & Spa [](https://www.expedia.co.uk/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information) La Cantera District 9.0/10 Wonderful (1,022 reviews) "Overall good stay. Would definitely stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Batool £323 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/29446190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/416e70de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/54fbc661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Antonio North [](https://www.expedia.co.uk/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) Vance Jackson 8.6/10 Excellent (1,298 reviews) "Great rooms, geeat bar, and great pool! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dustanna £79 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/223492d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a92bc437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/8588d651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG [](https://www.expedia.co.uk/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) Northwest Side 7.8/10 Good (1,088 reviews) "Clean room and the staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nyla £83 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/065f54d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/8e330921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/ed67c17c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2220400/2220322/1bfd1013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites at Six Flags [](https://www.expedia.co.uk/San-Antonio-Hotels-Sleep-Inn-Suites-At-Six-Flags.h2220322.Hotel-Information) Northwest Side 7.8/10 Good (1,002 reviews) "The staff was very courteous." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda £52 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Sleep-Inn-Suites-At-Six-Flags.h2220322.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/67193bbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/1dc39474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/f80fef97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1470000/1465500/1465404/5a0d6e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham San Antonio/NW Medical Center [](https://www.expedia.co.uk/San-Antonio-Hotels-Howard-Johnson-By-Wyndham-San-AntonioNW-Medical-Center.h1465404.Hotel-Information) Balcones Heights 6.8/10 (1,002 reviews) "Dirty walls. Black mold on mini fridge. Stains on sofa bed. Stains on the mattresses of the beds. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/San-Antonio-Hotels-Howard-Johnson-By-Wyndham-San-AntonioNW-Medical-Center.h1465404.Hotel-Information) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/8db3c38d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/b25710dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/b607efdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/9e3e8920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark By Hilton San Antonio Northwest near Six Flags [](https://www.expedia.co.uk/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information) La Cantera District 8.0/10 Very good (2,011 reviews) "Clean room, quiet surroundings, nearby restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Norma £55 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/44e1c752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed with Sofa bed, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/340f3520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/2da07b84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1180000/1174100/1174009/d27582bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn & Suites San Antonio [](https://www.expedia.co.uk/San-Antonio-Hotels-University-Inn-Suites-San-Antonio.h1174009.Hotel-Information) Northwest Side 7.4/10 Good (1,002 reviews) "The staff was excellent and the rooms clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria £44 includes taxes & fees 1 Apr - 2 Apr [](https://www.expedia.co.uk/San-Antonio-Hotels-University-Inn-Suites-San-Antonio.h1174009.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/ded9f09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/w9000h6173x0y15-23603cae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/d85458fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) Medical Center District 8.4/10 Very good (3,211 reviews) "Nice, clean, quiet, easy, quick check in and check out, nice pool and hot tub" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) donald £78 includes taxes & fees 19 Mar - 20 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/e8a306b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/6c1ef092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/0f02ca59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20296/0c7a5109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn By Wyndham IH-10 West San Antonio TX [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-By-Wyndham-San-Antonio-Vance-Jackson.h20296.Hotel-Information) Northwest Los Angeles Heights 6.2/10 (1,002 reviews) "The door lock was broken" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jesus £47 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-By-Wyndham-San-Antonio-Vance-Jackson.h20296.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28®ionId=6059170&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6059170) ## Top Northwest San Antonio Hotel Reviews ![La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW](https://images.trvl-media.com/lodging/2000000/1620000/1614000/1613977/3b4d6808_y.jpg) ### La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW 10/10 Excellent "The room was clean, great location near restaurants and the staff was so friendly. " [](https://expedia.co.uk/San-Antonio-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Antonio-Medical-Ctr-NW.h1613977.Hotel-Information) ![Drury Inn & Suites Near La Cantera Parkway](https://images.trvl-media.com/lodging/3000000/2190000/2180400/2180355/b30bcf7c_y.jpg) ### Drury Inn & Suites Near La Cantera Parkway 10/10 Excellent "Our experience at the Drury Inn & Suites Near La Cantera Parkway was excellent. The room was cleaned and the bed was very comfortable (better than my bed at home). I had never seen so many people taking advantage of the delicious hot breakfast. I also liked that you had dinner available for your guest and happy hour. You are definitely our choice for our next stay in San Antonio. Thank you" [](https://expedia.co.uk/San-Antonio-Hotels-Drury-Inn-Suites-Near-La-Cantera-Parkway.h2180355.Hotel-Information) ![Spark By Hilton San Antonio Northwest near Six Flags](https://images.trvl-media.com/lodging/1000000/50000/41300/41271/8db3c38d_y.jpg) ### Spark By Hilton San Antonio Northwest near Six Flags 10/10 Excellent "Very clean rooms and friendly staff." [](https://expedia.co.uk/San-Antonio-Hotels-Quality-Inn-San-Antonio-Fiesta-At-Six-Flags.h41271.Hotel-Information) ![Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG](https://images.trvl-media.com/lodging/10000000/9330000/9330000/9329921/a5ac356f_y.jpg) ### Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG 8/10 Good "The room looked nicer in the pictures. Dents in the walls and needed some repainting. Room was spacious and clean. Staff was friendly." [](https://expedia.co.uk/San-Antonio-Hotels-Holiday-Inn-Express-Suites-San-Antonio-Medical-Six-Flags.h9329921.Hotel-Information) ![Best Western Medical Center North Inn & Suites Near Six Flags](https://images.trvl-media.com/lodging/2000000/1350000/1348700/1348602/dbdba210_y.jpg) ### Best Western Medical Center North Inn & Suites Near Six Flags 10/10 Excellent "Good" [](https://expedia.co.uk/San-Antonio-Hotels-Best-Western-Medical-Center-North-Inn-Suites-Near-Six-Flags.h1348602.Hotel-Information) ![Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort](https://images.trvl-media.com/lodging/5000000/4920000/4919800/4919718/d38f20a3_y.jpg) ### Bluegreen Vacations Eilan Hotel and Spa, an Ascend Collection Resort 10/10 Excellent "." [](https://expedia.co.uk/San-Antonio-Hotels-Eilan-Hotel-And-Spa.h4919718.Hotel-Information) ![The Westin San Antonio North](https://images.trvl-media.com/lodging/1000000/10000/3200/3187/b99867e6_y.jpg) ### The Westin San Antonio North 10/10 Excellent "Clean" [](https://expedia.co.uk/San-Antonio-Hotels-Omni-San-Antonio-Hotel-At-The-Colonnade.h3187.Hotel-Information) ![Signia by Hilton La Cantera Resort & Spa](https://images.trvl-media.com/lodging/1000000/290000/284400/284306/w3840h2556x0y4-935acc4f_y.jpg) ### Signia by Hilton La Cantera Resort & Spa 10/10 Excellent "Floor Seven was excellent!" [](https://expedia.co.uk/San-Antonio-Hotels-Signia-By-Hilton-La-Cantera-Resort-Spa.h284306.Hotel-Information) ![Hyatt Place San Antonio-Northwest/Medical Center](https://images.trvl-media.com/lodging/1000000/50000/41800/41734/cb7f797a_y.jpg) ### Hyatt Place San Antonio-Northwest/Medical Center 10/10 Excellent "Everything was clean, friendly staff, really nice and comfy place …breakfast honestly need to be improved, not much flavor on the food Everything else 👍" [](https://expedia.co.uk/San-Antonio-Hotels-Hyatt-Place-San-Antonio-NorthwestMedical-Center.h41734.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [3 Star Hotels in North San Antonio - SAT ](https://www.expedia.co.uk/3Star-North-San-Antonio-SAT-Hotels.s30-0-d553248633938962547.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Alamo Plaza ](https://www.expedia.co.uk/Alamo-Plaza-Hotels-Boutique-Hotel.0-0-d6229132-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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