A large eye sculpture in a park surrounded by trees.

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Our top choices for Northeast Missouri hotels with a spa

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1,002 reviews)
"Clean rooms, comfy beds, nice pool and good variety at breakfast. Couldn’t ask for much more!"
United States
Sarah
The price is £96
includes taxes & fees
6 Dec - 7 Dec
Sleep Inn & Suites Hannibal West

2. Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.8 out of 10, Excellent, (1,008 reviews)
"Location was great!"
United States
Rob
The price is £87
includes taxes & fees
10 Nov - 11 Nov
Best Western On The River

3. Depot Inn and Suites

Depot Inn and Suites
3.5 star property
La Plata
9.8 out of 10, Exceptional, (750 reviews)
"The train museum, indoor pool, bikes and pool table make the Depot inn a great place. The clean rooms and friendly staff make it a must stay."
United States
Kimberly
The price is £74
includes taxes & fees
6 Dec - 7 Dec
Depot Inn and Suites

4. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
Canton
9.2 out of 10, Wonderful, (1,006 reviews)
"As always the stay was great"
United States
Peter
The price is £79
includes taxes & fees
10 Dec - 11 Dec
Oak Hill Inn & Suites

5. Hampton Inn By Hilton Warrenton I-70

Hampton Inn By Hilton Warrenton I-70
Warrenton
9.8 out of 10, Exceptional, (11 reviews)
"Good location friendly staff Clean"
United States
Richard
The price is £118
includes taxes & fees
10 Dec - 11 Dec
Hampton Inn By Hilton Warrenton I-70

6. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very good, (1,006 reviews)
"Our go to hotel for years when we visit Hannibal."
United States
Gayle
The price is £63
includes taxes & fees
6 Dec - 7 Dec
Quality Inn & Suites Hannibal West

7. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
Louisiana
9.6 out of 10, Exceptional, (28 reviews)
"Cutest place to stay in Louisiana Missouri"
United States
Kimberly
The price is £92
includes taxes & fees
23 Nov - 24 Nov
The Eagles Nest Inn

8. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.4 out of 10, Exceptional, (26 reviews)
"Amazing place to stay! You can’t beat the indoor pool whether it is storming or feels like the fires from hell are raining on earth you can still enjoy a great swim without worrying about lightning or burning to death. The people are incredibly kind and on top of anything you may need and the cabins are a perfect relaxing get away with nice a/c and plenty of sleeping space! Thank you for another amazing stay!"
United States
Erika
The price is £82
includes taxes & fees
10 Nov - 11 Nov
Cannon Dam Cabins

9. Town & Country Inn and Suites

Town & Country Inn and Suites
2.5 star property
Quincy
9.2 out of 10, Wonderful, (950 reviews)
"Everything was A+"
United States
Kelly
The price is £107
includes taxes & fees
15 Nov - 16 Nov
Town & Country Inn and Suites

10. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
2.0 star property
Monroe City
8.4 out of 10, Very good, (496 reviews)
"Nice place to stop for a one night stay."
United States
Ron
The price is £68
includes taxes & fees
10 Dec - 11 Dec
FairBridge Inn Express, Monroe City

11. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.6 out of 10, Exceptional, (1,004 reviews)
"All the people were very nice and talkative. The happy hour food was good and so were the cocktails. The hotel was clean and comfortable."
United States
Michael
The price is £95
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites St. Louis St. Peters

12. Best Western Teal Lake Inn

Best Western Teal Lake Inn
2.5 star property
Mexico
8.4 out of 10, Very good, (574 reviews)
"Property was close to all needed businesses"
United States
Elizabeth
The price is £78
includes taxes & fees
10 Nov - 11 Nov
Best Western Teal Lake Inn

13. Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
Quincy
8.6 out of 10, Excellent, (484 reviews)
"Very nice clean friendly"
United States
paul
The price is £62
includes taxes & fees
10 Dec - 11 Dec
Heritage Hotel Quincy

14. Bay Inn & Suites Troy

Bay Inn & Suites Troy
2.5 star property
Troy
9.4 out of 10, Exceptional, (62 reviews)
"Nice place to stay ."
United States
Judy Ann
The price is £62
includes taxes & fees
6 Dec - 7 Dec
Bay Inn & Suites Troy

15. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (205 reviews)
"Very nice room and great view of the river. Very comfortable bed and very nice shower. Walking distance to so many restaurants and shops. We enjoyed our stay very much!"
United States
Christina
The price is £157
includes taxes & fees
10 Nov - 11 Nov
Riverside Inn Hannibal

16. River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (225 reviews)
"Loved this property! Beds were so comfortable, large walk-in shower and decor was amazing!"
United States
Bet
The price is £97
includes taxes & fees
6 Dec - 7 Dec
River Sirens Hotel

17. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (773 reviews)
"Front desk helpful Clean rooms Great breakfast and lady fixing our breakfast was helpful and kept plenty of food ready for all"
United States
Jerry
The price is £67
includes taxes & fees
25 Nov - 26 Nov
Comfort Inn & Suites - Hannibal

18. River's Edge Motel

River's Edge Motel
2.0 star property
Louisiana
8.8 out of 10, Excellent, (395 reviews)
"Nice location."
United States
Jeff
The price is £71
includes taxes & fees
8 Dec - 9 Dec
River's Edge Motel

19. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (457 reviews)
"Great stay! Definitely will be back to stay there on my next visit to St. Peters!"
United States
Roxanne
The price is £106
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites St Peters by IHG

20. Central Hotel

Central Hotel
3.5 star property
New Haven
9.8 out of 10, Exceptional, (129 reviews)
"A wonderful place to stay! The rooms were clean, comfy and wonderfully decorated. The innkeeper was helpful and very friendly. A beautiful property that give off the vibe your staying with friends! Highly recommend"
United States
James M
The price is £127
includes taxes & fees
10 Nov - 11 Nov
Central Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Northeast Missouri

Spa hotels with free breakfast in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Northeast Missouri Hotel Reviews