Northeast Missouri Holidays

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Your Northeast Missouri Holiday

Book one of our holiday packages to Northeast Missouri and go wherever your inner adventurer desires. If that includes St. Louis, the dining and culture are just the start of the things to look forward to in this wonderful city. A trip to Northeast Missouri wouldn't be complete without spending some time in its leading cities, starting with St. Louis. Two of the top attractions here include Enterprise Centre and Busch Stadium. Maryland Heights should also be on the itineraries of all Northeast Missouri travellers. Visitors to this exciting city enjoy Ameristar Casino St. Charles and Westport Plaza. Expedia has hotels, flights, car rentals and more to help you put together your very own tailored Northeast Missouri holiday today.

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Where to stay in Northeast Missouri

Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
St. Louis Missouri

Clayton

1 out of top 10 points of interest in this area

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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Northeast Missouri Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

Top hotels in Northeast Missouri

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £81 per night from 4 Mar to 5 Mar
£81
4 Mar - 5 Mar
includes taxes & fees
8.8/10 Excellent! (1,852 reviews)
Room was excellent and the house keeper was outstanding

Reviewed on 26 Feb 2026

Pear Tree Inn St. Louis Near Union Station
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £113 per night from 23 Mar to 24 Mar
£113
23 Mar - 24 Mar
includes taxes & fees
9/10 Wonderful! (1,625 reviews)
Great service. Would definitely stay again

Reviewed on 27 Feb 2026

21C Museum Hotel St Louis
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is £78 per night from 9 Mar to 10 Mar
£78
9 Mar - 10 Mar
includes taxes & fees
9.4/10 Exceptional! (2,834 reviews)
We had a flight disruption and needed a close, affordable and clean stay. They had shuttle service.

Reviewed on 27 Feb 2026

Pear Tree Inn St. Louis Airport
See all 2,852 properties in Northeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Saint Louis is a City and Urban Center is Missouri with the Iconic Arch

Dome at America’s Center

5/5(4 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and great live music.

Dome at America’s Center
Located between St Louis and Springfield, Missouri, Meramec Caverns has some extraordinary cave formations. There are 4.6 miles of caverns tucked away in the Ozark Mountains. Artifacts from Pre- Colombian Native American Indians have been found in the caverns and it is ruptured that outlaw Jessie James used them as a hideout. Also Union troops camped out inside the huge opening at the beginning of the caverns #Golden

Meramec Caverns

Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the cafes.

Meramec Caverns
Missouri Botanical Gardens and Arboretum featuring autumn leaves, modern architecture and a park

Missouri Botanical Gardens and Arboretum

5/5(2 reviews)

Spend a day exploring historic buildings and an indoor rainforest at the oldest botanical garden in the U.S.

Missouri Botanical Gardens and Arboretum

What to do in Northeast Missouri

Kansas City: Kansas City Tap Tour

Kansas City: Kansas City Tap Tour

£4
per adult
Kansas City: Kansas City Tap Tour
Tom’s Town Distilling Co., the first legal distillery in downtown KC since Prohibition, produces premium craft spirits including award-winning Bourbon, Gin, Barreled Gin and Vodka.

Tom's Town Distillery Tour and Tasting

£20
per adult
100% of travellers recommend
Tom's Town Distillery Tour and Tasting
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

£26
per adult
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
See all activities in Northeast Missouri

Frequently asked questions

Can I cancel my flight booking to Northeast Missouri due to COVID-19?
Our Customer Service Portal has important information about cancelling or changing your flight due to COVID-19. Before you reserve a seat, it's wise to read the terms and conditions of your airfare too.
What's the best way to find cheap flights to Northeast Missouri that have flexible change policies?
It's as easy as 1-2-3 with Expedia. Step 1: Type in your travel dates and hit "Search." Next, check "No change fee" under the "Flexible change policies" subheading on the top left of your screen. Step 3. Score a cheap and flexible flight to Northeast Missouri.
What are some of the general tips for travellers to Northeast Missouri during the COVID-19 outbreak?
As a result of the COVID-19 pandemic, travelling now comes with a few more challenges than usual. Make a note of these worthwhile tips before boarding your flight to Northeast Missouri:
  • Research if any travel restrictions apply to your origin and destination before committing to a flight. Also check if there are any conditions you'll have to follow on arrival, such as taking a COVID-19 test.
  • Requirements state you must wear a face mask at the airport, including at screening checkpoints. You should be prepared to adjust your mask for identification purposes when asked by a TSA employee.
  • To minimize the risk of cross-contamination, position your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA employee.
  • TSA is now permitting passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on luggage. This will need to be removed from your bag to be screened.
  • Place any personal items (like your phone and wallet) in your carry-on rather than a bin to reduce handling during screening.
  • If you're bringing food through the screening checkpoint, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA officer will need to touch your carry-on bag or food container for closer inspection.

Which airlines fly to Northeast Missouri?
Arrange your fare with American Airlines and start working on your Northeast Missouri must-do list. This popular airline offers 898 flights per month to Lambert-St. Louis Intl. Airport (STL), a main gateway.
How can I find cheap tickets to Northeast Missouri?
You'll always find a terrific deal with Expedia, but our "flexible dates" search function makes it that much easier. Enter your preferred travel date, then tick the flexible dates box above to see the cheapest prices for nearby days. was the lowest price for a flight to Northeast Missouri in the last seven days.
How much is a flight to Northeast Missouri?
If you were journeying one way from (), you could've snapped up a low-cost fare for just in the last seven days. Return flights to Northeast Missouri ranged from to over the same period.
What are the most popular airports to fly into in Northeast Missouri?
The principal gateway to Northeast Missouri, roughly 5579 flights service Lambert-St. Louis Intl. Airport (STL) each month. Look for a top deal, reserve your seat and get set to soak up the best of this renowned region.
When is the cheapest time to fly to Northeast Missouri?
If you'd prefer to spend your holiday dollars on having fun in Northeast Missouri rather than on your flight there, depart early in the week. The most cost-effective day to fly is generally Tuesday, with Monday coming in second. With many folks travelling over the weekend, Saturday typically has the costliest airfares.
How much is a plane ticket to Northeast Missouri?
In the last seven days, plane fares to Northeast Missouri varied between and . Prices tend to rise over time, so find a bargain today.
Which airlines with flights to Northeast Missouri employ COVID-19 cleanliness policies?
In order to limit contact between travellers and cabin crew during the COVID-19 outbreak, most airlines have taken social distancing and other measures to the skies. Just some of these are:
  • Southwest Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.