Title: Cheap Flights from Chicago to Kirksville (ORD to IRK) - Expedia.co.uk ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from Chicago (ORD) to Kirksville (IRK) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Chicago O'Hare International Airport (ORD) to Kirksville, MO (IRK-Kirksville Municipal) - ![Contour Airlines](https://a.travel-assets.com/air/airlines/lf_sq.svg) Contour Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:ord,to:irk,departure:14/11/2025TANYT&leg2=from:irk,to:ord,departure:21/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LF"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) Flight from Chicago to Kirksville route information | Origin airport | O'Hare Intl. | | --- | --- | | Destination airport | Kirksville Municipal | | Distance | 438 km | | Average flight time | 1 hour 25 mins | ## Compare flights from Chicago to Kirksville easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Chicago to Kirksville. Operating between them flights per day, airlines cover the route. And fly direct, getting you to Kirksville Municipal in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from O'Hare Intl. to Kirksville Municipal.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from O'Hare Intl. (ORD) to Kirksville Municipal (IRK) The easiest way to view the best deals on flights from Chicago to Kirksville today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from O'Hare Intl. to Kirksville Municipal start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Chicago and Kirksville - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Chicago to Kirksville flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from O'Hare Intl. to Kirksville Municipal for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other ### Accommodation - [Brookfield Hotels](https://www.expedia.co.uk/Brookfield-Hotels.d55605.Travel-Guide-Hotels) - [Cairo Hotels](https://www.expedia.co.uk/Cairo-Hotels.d553248634983322461.Travel-Guide-Hotels) - [Callao Hotels](https://www.expedia.co.uk/Callao-Hotels.d3000444667.Travel-Guide-Hotels) - [Downing Hotels](https://www.expedia.co.uk/Downing-Hotels.d3000349344.Travel-Guide-Hotels) - [Edina Hotels](https://www.expedia.co.uk/Edina-Hotels.d3000444857.Travel-Guide-Hotels) - [Ethel Hotels](https://www.expedia.co.uk/Ethel-Hotels.d102383.Travel-Guide-Hotels) - [Gibbs Hotels](https://www.expedia.co.uk/Gibbs-Hotels.d3000444924.Travel-Guide-Hotels) - [Harris Hotels](https://www.expedia.co.uk/Harris-Hotels.d3000444953.Travel-Guide-Hotels) - [Huntsville Hotels](https://www.expedia.co.uk/Huntsville-Hotels.d3000445023.Travel-Guide-Hotels) - 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