Title: TOP Adults Only Resorts & Hotels in Mission Valley, CA for 2026 |  Expedia.co.uk

[Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Mission Valley Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Valley.d800124.Car-Hire-Guide)[Mission Valley Holidays](https://expedia.co.uk/Mission-Valley.d800124.Holidays-City-Breaks)

![Closeup of the Adobe walls of the historic Mission De Alcala San Diego California](https://images.trvl-media.com/place/800124/80ddc530-f226-4f74-8ff4-45354a1ef339.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Search Adults Only Resorts & Hotels in Mission Valley

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## Check availability on Mission Valley Adults Only Resorts & Hotels

Tonight

[9 Dec - 10 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=800124&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

Tomorrow

[10 Dec - 11 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=800124&startDate=2025-12-10&endDate=2025-12-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

This weekend

[12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=800124&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

Next weekend

[19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=800124&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only)

## Our top choices for Mission Valley adults-only hotels

![3 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/1f4c359a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/8995625e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![7 restaurants, breakfast served](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/7910f1d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/34000000/33670000/33661500/33661441/91cdc1c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sycuan Casino Resort

El Cajon

9.2/10

Wonderful

(1634)

"Nice hotel and friendly staff. Will definitely stay again ."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lorna

[](https://www.expedia.co.uk/El-Cajon-Hotels-Sycuan-Casino-Resort.h33661441.Hotel-Information)

![Memory-foam beds, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/dc9bc184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/04f95010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/2180fd33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Billiards](https://images.trvl-media.com/lodging/55000000/54920000/54911400/54911318/6fdbf120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stay Classy Hostel

Downtown San Diego

9.6/10

Exceptional

(783)

"Good place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sai

[](https://www.expedia.co.uk/San-Diego-Hotels-Stay-Classy.h54911318.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-24&endDate=2025-12-25&regionId=800124&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true)

## Top Mission Valley Hotel Reviews

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

10/10 Excellent

"Very clean hotel and the people that cleans are really nice. Perfect to visit San Diego, great location."

[](https://expedia.co.uk/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

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