Mission Valley Holidays from £885

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to £335 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Packages with flights are ATOL protected

Your Mission Valley Holiday

With a customized holiday package to Mission Valley, you'll spend less time planning and more time experiencing this interesting neighbourhood. From its shopping to its dining, there's so much to discover here. Not sure what to do and see during your trip to Mission Valley? Nearby attractions like San Diego Zoo, Balboa Park and University of San Diego are great places to start. Expedia will help you turn your ideal Mission Valley holiday into reality, whatever your travel plans or budget.

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo San Diego-Gaslamp Quarter by IHG
La Jolla Shores Hotel
Estancia La Jolla Hotel & Spa
Pacific Terrace Hotel
The Dana on Mission Bay

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley

Top hotels in Mission Valley

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
8/10 Very Good! (1,918 reviews)
"I think it was a good experience. Rooms were decent, the service is excellent. I will be coming back!"

Reviewed on 8 Aug 2025

Handlery Hotel
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is £115 per night from 17 Aug to 18 Aug
£115
17 Aug - 18 Aug
includes taxes & fees
8.6/10 Excellent! (1,155 reviews)
"Overall the hotel it’s nice. Just the room it’s small"

Reviewed on 6 Aug 2025

Hampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
The price is £109 per night from 31 Aug to 1 Sept
£109
31 Aug - 1 Sept
includes taxes & fees
8.4/10 Very Good! (1,475 reviews)
"When asked if they had handicap parking, staff assumed I needed a wheelchair access room with an open shower even though my wife and I walked in. Shower made a mess on the floor."

Reviewed on 9 Aug 2025

Sheraton Mission Valley San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Valley travel package cost?
The cheapest Mission Valley package is £885, so your dream escape can become a reality — without burning a hole in your pocket. Combine flights, hotels, car rentals and more to build a package that matches your travelling style.
If I'm not able to travel, can I cancel my Mission Valley travel package?
It's impossible to predict what the future holds, so it's comforting to know that you can change or cancel your Mission Valley travel package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal to find out more.
How do I get a cheap travel package to Mission Valley?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you dollars too. A Mission Valley travel package makes it a breeze to create your ideal trip. With more than 550 airlines around the world to choose from, finding convenient flights that suit your schedule won't be a problem. On top of that, we have over 1,000,000 hotel options globally to pick from. Talk about choice! No matter who you are, Expedia will help show you the world.
Does Expedia offer Book Now, Pay Later Mission Valley holidays?
Yes, we do. Expedia has partnered with online lender Klarna to help you conveniently pay for your holiday in instalments. Simply click on the payment plan that works for you during the checkout process and take away the stress of budgeting for your trip. Don't forget to bundle your flights, accommodation and car hire with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make your holiday dreams come true.
  • Pay in instalments holidays: If you'd prefer to pay off your escape in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this plan. Simply put down a small deposit on your escape and then get on your way.

Where should I stay in Mission Valley?
Holiday makers come from all over the world to experience SeaWorld and San Diego Zoo in Mission Valley. Book yourself a room within a stone's throw of these top attractions and visit them at your leisure.
What are the top hotels in Mission Valley?
Manchester Grand Hyatt San Diego and Paradise Point Resort And Spa are among the most popular hotels in Mission Valley. Why not look up the facilities and rates at each and then make a decision?
How far in advance should I book my Mission Valley holiday?
To bag rock-bottom prices, book ASAP. Airlines generally advertise flight tickets, along with some of the lowest fares, nearly a year prior to departure. Hotels, car rental and experiences should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway to Mission Valley, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Mission Valley travel package include?
Hotels, car rentals and flights — we bring you the best deals. All you have to do is pick your preferred combination. Once you've made your booking, you can add on the exciting stuff like tours and experiences. Our travel packages make it easy to craft an awesome Mission Valley holiday.
What should I know before booking a Mission Valley travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your trip. For example, bundle your hotels, flights and rental cars and score big savings. No matter your holiday plans, you're sure to find a package that fits your budget.
Can I choose my airline with a Mission Valley Expedia travel package?
Yes, so take your pick! We have access to over 550 partner airlines around the world, so you can customize your Mission Valley trip according to your budget and travel needs.

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.