Mission Valley Holidays

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Your Mission Valley Holiday

With a customized holiday package to Mission Valley, you'll spend less time planning and more time experiencing this interesting neighbourhood. From its shopping to its dining, there's so much to discover here. Not sure what to do and see during your trip to Mission Valley? Nearby attractions like San Diego Zoo, Balboa Park and University of San Diego are great places to start. Expedia will help you turn your ideal Mission Valley holiday into reality, whatever your travel plans or budget.

Price found within the past 48 hours. Click for updated prices.
  • Exterior
    Aug 8 - Aug 15

    The Sofia Hotel + Flight

    Downtown San Diego
    7 nights
    3.5 star property
    8.6/10 - Excellent (2,126 reviews)
    "Good location easy to find restaurant and public transportation"
    Reviewed May 26, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • Direct SAN - LHR • Direct
    £2,129
    £1,556
    per traveller
    found 1 day ago
    The Sofia Hotel
  • Standard Single Room, Oceanfront | View from room
    Jul 27 - Aug 10

    Ocean Park Inn + Flight

    Pacific Beach
    14 nights
    3.0 star property
    9.4/10 - Exceptional (1,010 reviews)
    "Hotel was great and the beachside access was amazing and it was very convenient to be close to a lot of stores and restaurants."
    Reviewed May 26, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • Direct SAN - LHR • Direct
    Save 100% on your flight
    £5,450
    £3,527
    per traveller
    found 1 day ago
    Ocean Park Inn
  • Garden
    Jul 7 - Jul 21

    Guesthouse Hotel at La Valle + Flight

    Rancho Santa Fe
    14 nights
    4.5 star property
    9.4/10 - Exceptional (117 reviews)
    "Great place to stay in the San Diego area, located in a high-end neighborhood inside a golf club. The rooms, which appear to have been recently and tastefully renovated, are spacious, clean, and quiet. The welcome amenities (gummy bears and nuts) are a nice touch. We will definitely stay here again when we’re back in the area. The only minor downside for us was the lack of a full sit-down breakfast service, although there are plenty of places for breakfast just a short drive away."
    Reviewed May 18, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • Direct SAN - LHR • Direct
    Save 100% on your flight
    £2,911
    £1,940
    per traveller
    found 1 day ago
    Guesthouse Hotel at La Valle
  • Apartment (2 Bedrooms) | Interior
    Jul 27 - Aug 10

    Oceanfront in La Jolla, Steps to Beach, Shops, Dining Dawn Patrol by Avantstay + Flight

    Village of La Jolla
    14 nights
    3.0 star property
    8.0/10 - Very good (1 review)
    "The view was amazing! We had some trouble with the lock on the apartment door but eventually figured out that we had to pull on the handle in order for it to all the way into the slot. I notified the avant- team and they did they were going to send someone over, but they did not. Also the garage did not have enough clearance to put our rental SUV into. This caused issues with parking until we talked to a guy who was remodeling another apartment. Thank goodness for him because I talked to two..."
    Reviewed May 9, 2026
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • Direct SAN - LHR • Direct
    Save 100% on your flight
    £8,571
    £6,029
    per traveller
    found 1 day ago
    Oceanfront in La Jolla, Steps to Beach, Shops, Dining Dawn Patrol by Avantstay
  • House (4 Bedrooms) | Interior
    Jul 27 - Aug 10

    Ormond Court Collection by Avantstay Coastal 3-units Compound + Patio + BBQ Walk to Beach + Flight

    Mission Beach
    14 nights
    3.0 star property
    Return • London (LHR) - San Diego (SAN)
    LHR - SAN • Direct SAN - LHR • Direct
    Save 100% on your flight
    £9,770
    £6,914
    per traveller
    found 1 day ago
    Ormond Court Collection by Avantstay Coastal 3-units Compound + Patio + BBQ Walk to Beach

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley
Downtown San Diego

Downtown San Diego

4 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Top hotels in Mission Valley

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
The price is £84 per night from 27 May to 28 May
£84
27 May - 28 May
includes taxes & fees
8/10 Very Good! (2,735 reviews)
"Minor room issue was handled. Overall pleasant stay"

Reviewed on 26 May 2026

Days Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is £70 per night from 27 May to 28 May
£70
27 May - 28 May
includes taxes & fees
8/10 Very Good! (3,555 reviews)
"Clean room, but no trash bags for the bins. Staff got up to help just because another employee asked for her to check me in."

Reviewed on 26 May 2026

Best Western Seven Seas
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
The price is £87 per night from 1 Jun to 2 Jun
£87
1 Jun - 2 Jun
includes taxes & fees
8.4/10 Very Good! (2,546 reviews)
"No elevators. Dismal to carry your bags upstairs. Room was nice but needs more lighting. Quiet even though close to freeway. Convenient to everywhere."

Reviewed on 26 May 2026

Handlery Hotel
See all 8,923 properties in Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Mission Valley travel package cost?
The cheapest Mission Valley package is , so your dream escape can become a reality — without burning a hole in your pocket. Combine flights, hotels, car rentals and more to build a package that matches your travelling style.
If I'm not able to travel, can I cancel my Mission Valley travel package?
It's impossible to predict what the future holds, so it's comforting to know that you can change or cancel your Mission Valley travel package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal to find out more.
How do I get a cheap travel package to Mission Valley?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you dollars too. A Mission Valley travel package makes it a breeze to create your ideal trip. With more than 550 airlines around the world to choose from, finding convenient flights that suit your schedule won't be a problem. On top of that, we have over 1,000,000 hotel options globally to pick from. Talk about choice! No matter who you are, Expedia will help show you the world.
Does Expedia offer Book Now, Pay Later Mission Valley holidays?
Yes, we do. Expedia has partnered with online lender Klarna to help you conveniently pay for your holiday in instalments. Simply click on the payment plan that works for you during the checkout process and take away the stress of budgeting for your trip. Don't forget to bundle your flights, accommodation and car hire with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in convenient monthly instalments will make your holiday dreams come true.
  • Pay in instalments holidays: If you'd prefer to pay off your escape in multiple transactions, holidays paid in instalments might be the best option for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this plan. Simply put down a small deposit on your escape and then get on your way.

Where should I stay in Mission Valley?
Holiday makers come from all over the world to experience SeaWorld and San Diego Zoo in Mission Valley. Book yourself a room within a stone's throw of these top attractions and visit them at your leisure.
What are the top hotels in Mission Valley?
Manchester Grand Hyatt San Diego and Paradise Point Resort And Spa are among the most popular hotels in Mission Valley. Why not look up the facilities and rates at each and then make a decision?
How far in advance should I book my Mission Valley holiday?
To bag rock-bottom prices, book ASAP. Airlines generally advertise flight tickets, along with some of the lowest fares, nearly a year prior to departure. Hotels, car rental and experiences should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway to Mission Valley, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Mission Valley travel package include?
Hotels, car rentals and flights — we bring you the best deals. All you have to do is pick your preferred combination. Once you've made your booking, you can add on the exciting stuff like tours and experiences. Our travel packages make it easy to craft an awesome Mission Valley holiday.
What should I know before booking a Mission Valley travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your trip. For example, bundle your hotels, flights and rental cars and score big savings. No matter your holiday plans, you're sure to find a package that fits your budget.
Can I choose my airline with a Mission Valley Expedia travel package?
Yes, so take your pick! We have access to over 550 partner airlines around the world, so you can customize your Mission Valley trip according to your budget and travel needs.

Things to do

LEGOLAND® California Resort

LEGOLAND® California Resort

£54
per adult
84% of travellers recommend
LEGOLAND® California Resort
San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

£65
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

£52
per adult
86% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
See all activities in San Diego

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.