Title: Full-size Central San Diego Car Hire | Expedia.co.uk ![](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Full-size Car Hire Companies in Central San Diego ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Fullsize Car Hire Information | Car type: | Fullsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - [3 Star Hotels in Sorrento Valley](https://www.expedia.co.uk/3Star-Sorrento-Valley-San-Diego-Hotels.s30-n6230625-0.Travel-Guide-Filter-Hotels) - [Birdland Hotels](https://www.expedia.co.uk/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels) - [Clairemont Mesa East Hotels](https://www.expedia.co.uk/Clairemont-Mesa-East-San-Diego-Hotels.0-n553248635976471258-0.Travel-Guide-Filter-Hotels) - [Clairemont Mesa West Hotels](https://www.expedia.co.uk/Clairemont-Mesa-West-San-Diego-Hotels.0-n553248635976473366-0.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Clairemont](https://www.expedia.co.uk/Clairemont-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n177692-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Clairemont Hotels](https://www.expedia.co.uk/Clairemont-San-Diego-Hotels.0-n177692-0.Travel-Guide-Filter-Hotels) - [Kearny Mesa Hotels](https://www.expedia.co.uk/Kearny-Mesa-San-Diego-Hotels.0-n3000663380-0.Travel-Guide-Filter-Hotels) - [Linda Vista Hotels](https://www.expedia.co.uk/Linda-Vista-San-Diego-Hotels.0-n553248635976388645-0.Travel-Guide-Filter-Hotels) - [Miramar Hotels](https://www.expedia.co.uk/Miramar-San-Diego-Hotels.0-n6230615-0.Travel-Guide-Filter-Hotels) - [Hotels near Montgomery Field](https://www.expedia.co.uk/Montgomery-Field-Airport-Hotels.0-aMYF-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in North Clairemont](https://www.expedia.co.uk/North-Clairemont-San-Diego-Hotels-Gay-Friendly-Hotel.0-n177693-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Serra Mesa Hotels](https://www.expedia.co.uk/Serra-Mesa-San-Diego-Hotels.0-n553248635953501652-0.Travel-Guide-Filter-Hotels) - [Sorrento Valley Hotels](https://www.expedia.co.uk/Sorrento-Valley-San-Diego-Hotels.0-n6230625-0.Travel-Guide-Filter-Hotels) - [Hotels near Stadium Golf Center & Batting Cages](https://www.expedia.co.uk/Stadium-Golf-Center-Batting-Cages-Hotels.0-l553248621555611799-0.Travel-Guide-Filter-Hotels) - [University City Hotels](https://www.expedia.co.uk/University-City-San-Diego-Hotels.0-n553248635976008131-0.Travel-Guide-Filter-Hotels) - [Flights from Montgomery Field](https://www.expedia.co.uk/lp/airports/myf/flights-from-montgomery-field-airport) - [Flights from Auckland (AKL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/akl/myf/auckland-to-san-diego) - [Flights from Alice (ALI) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ali/myf/alice-to-san-diego) - [Flights from Amsterdam (AMS) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ams/myf/amsterdam-to-san-diego) - [Flights from Atlanta (ATL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/atl/myf/atlanta-to-san-diego) - [Flights from Hartford (BDL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/bdl/myf/hartford-to-san-diego) - [Flights from Bishop (BIH) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/bih/myf/bishop-to-san-diego) - [Flights from Upland (CCB) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ccb/myf/upland-to-san-diego) - [Flights from Chadron (CDR) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/cdr/myf/chadron-to-san-diego) - [Flights from Columbus (CMH) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/cmh/myf/columbus-to-san-diego) - [Flights from Kiritimati (CXI) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/cxi/myf/kiritimati-to-san-diego) - [Flights from Calexico (CXL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/cxl/myf/calexico-to-san-diego) - [Flights from Douglas (DUG) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/dug/myf/douglas-to-san-diego) - [Flights from El Dorado (ELD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/eld/myf/el-dorado-to-san-diego) - [Flights from Fallon (FLX) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/flx/myf/fallon-to-san-diego) - [Flights from Gallup (GUP) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/gup/myf/gallup-to-san-diego) - [Flights from Helsinki (HEL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/hel/myf/helsinki-to-san-diego) - [Flights from Hot Springs (HOT) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/hot/myf/hot-springs-to-san-diego) - [Flights from Indianapolis (IND) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ind/myf/indianapolis-to-san-diego) - [Flights from New York (JFK) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/jfk/myf/new-york-to-san-diego) - [Flights from Manchester (MAN) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/man/myf/manchester-to-san-diego) - [Flights from Nacogdoches (OCH) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/och/myf/nacogdoches-to-san-diego) - [Flights from Oceanside (OCN) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ocn/myf/oceanside-to-san-diego) - [Flights from Miami (OPF) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/opf/myf/miami-to-san-diego) - [Flights from Chicago (ORD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ord/myf/chicago-to-san-diego) - [Flights from Peoria (PIA) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/pia/myf/peoria-to-san-diego) - [Flights from Pompano Beach (PPM) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ppm/myf/pompano-beach-to-san-diego) - [Flights from Los Angeles (QLA) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/qla/myf/los-angeles-to-san-diego) - [Flights from Raleigh (RDU) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/rdu/myf/raleigh-to-san-diego) - [Flights from Reynosa (REX) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/rex/myf/reynosa-to-san-diego) - [Flights from Rifle (RIL) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ril/myf/rifle-to-san-diego) - [Flights from Mariposa (RMY) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/rmy/myf/mariposa-to-san-diego) - [Flights from Sao Paulo (SAO) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sao/myf/sao-paulo-to-san-diego) - [Flights from Stockton (SCK) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sck/myf/stockton-to-san-diego) - [Flights from Spokane (SFF) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sff/myf/spokane-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/sfo/myf/san-francisco-to-san-diego) - [Flights from Salt Lake City (SLC) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/slc/myf/salt-lake-city-to-san-diego) - [Flights from Saranac Lake (SLK) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/slk/myf/saranac-lake-to-san-diego) - [Flights from Sacramento (SMF) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/smf/myf/sacramento-to-san-diego) - [Flights from Sydney (SYD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/syd/myf/sydney-to-san-diego) - [Flights from Santa Paula (SZP) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/szp/myf/santa-paula-to-san-diego) - [Flights from Tacoma (TIW) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/tiw/myf/tacoma-to-san-diego) - [Flights from Thermal (TRM) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/trm/myf/thermal-to-san-diego) - [Flights from Troutdale (TTD) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/ttd/myf/troutdale-to-san-diego) - [Flights from Concord (USA) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/usa/myf/concord-to-san-diego) - [Flights from Québec (YQB) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yqb/myf/quebec-to-san-diego) - [Flights from Yuma (YUM) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yum/myf/yuma-to-san-diego) - [Flights from Vancouver (YVR) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yvr/myf/vancouver-to-san-diego) - [Flights from Toronto (YYZ) to San Diego (MYF)](https://www.expedia.co.uk/lp/flights/yyz/myf/toronto-to-san-diego) - [Visit Birdland](https://www.expedia.co.uk/San-Diego-Birdland.dx553248635976479135) - [Visit Clairemont](https://www.expedia.co.uk/San-Diego-Clairemont.dx177692) - [Visit Miramar](https://www.expedia.co.uk/San-Diego-Miramar.dx6230615) - [Visit North Clairemont](https://www.expedia.co.uk/San-Diego-North-Clairemont.dx177693) - [Visit Sorrento Valley](https://www.expedia.co.uk/San-Diego-Sorrento-Valley.dx6230625) - [Car hire near Kearny Mesa](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kearny-Mesa.d3000663380.Car-Hire-Guide) - [Convertible Car Hire in San Diego County](https://www.expedia.co.uk/Convertible-Car-Rentals-In-San-Diego-County.d178304-tConvertible.Car-Rental-Destination-Class) - [Convertible Car Hire near San Diego Intl.](https://www.expedia.co.uk/Convertible-Car-Rentals-In-San-Diego-Intl.d5128531-tConvertible.Car-Rental-Guide-Class) - [Convertible Car Hire in San Diego](https://www.expedia.co.uk/Convertible-Car-Rentals-In-San-Diego.d3073-tConvertible.Car-Rental-Guide-Class) - [Economy Car Hire in East County](https://www.expedia.co.uk/Economy-Car-Rentals-In-East-County.d6056571-tEconomy.Car-Rental-Guide-Class) - [Economy Car Hire in Oceanside](https://www.expedia.co.uk/Economy-Car-Rentals-In-Oceanside.d9154-tEconomy.Car-Rental-Guide-Class) - [Economy Car Hire near San Diego Intl.](https://www.expedia.co.uk/Economy-Car-Rentals-In-San-Diego-Intl.d5128531-tEconomy.Car-Rental-Guide-Class) - [Full-Size Car Hire in Coronado](https://www.expedia.co.uk/Fullsize-Car-Rentals-In-Coronado.d5917-tFullsize.Car-Rental-Guide-Class) - [Full-Size Car Hire in San Diego](https://www.expedia.co.uk/Fullsize-Car-Rentals-In-San-Diego.d3073-tFullsize.Car-Rental-Guide-Class) - [Luxury Car Hire near San Diego Intl.](https://www.expedia.co.uk/Luxury-Car-Rentals-In-San-Diego-Intl.d5128531-tLuxury.Car-Rental-Guide-Class) - [Luxury Car Hire in San Diego](https://www.expedia.co.uk/Luxury-Car-Rentals-In-San-Diego.d3073-tLuxury.Car-Rental-Guide-Class) - [Midsize Car Hire in Coronado](https://www.expedia.co.uk/Midsize-Car-Rentals-In-Coronado.d5917-tMidsize.Car-Rental-Guide-Class) - [Mini Car Hire in Cuyamaca Rancho State Park](https://www.expedia.co.uk/Mini-Car-Rentals-In-Cuyamaca-Rancho-State-Park.d553248621532639209-tMini.Car-Rental-Guide-Class) - [Mini Car Hire near San Diego Intl.](https://www.expedia.co.uk/Mini-Car-Rentals-In-San-Diego-Intl.d5128531-tMini.Car-Rental-Guide-Class) - [Minivan Car Hire in Oceanside](https://www.expedia.co.uk/Minivan-Car-Rentals-In-Oceanside.d9154-tMinivan.Car-Rental-Guide-Class) - [Minivan Car Hire in South Bay](https://www.expedia.co.uk/Minivan-Car-Rentals-In-South-Bay.d6056572-tMinivan.Car-Rental-Guide-Class) - [Pickup Car Hire in Coronado](https://www.expedia.co.uk/Pickup-Car-Rentals-In-Coronado.d5917-tPickup.Car-Rental-Guide-Class) - [Pickup Car Hire in Laguna Beach](https://www.expedia.co.uk/Pickup-Car-Rentals-In-Laguna-Beach.d8384-tPickup.Car-Rental-Guide-Class) - [Pickup Car Hire in San Diego](https://www.expedia.co.uk/Pickup-Car-Rentals-In-San-Diego.d3073-tPickup.Car-Rental-Guide-Class) - [Suv Car Hire in North Mission Beach](https://www.expedia.co.uk/SUV-Car-Rentals-In-North-Mission-Beach.d553248635975749225-tSUV.Car-Rental-Guide-Class) - [Suv Car Hire near San Diego Intl.](https://www.expedia.co.uk/SUV-Car-Rentals-In-San-Diego-Intl.d5128531-tSUV.Car-Rental-Guide-Class) - [Sports Car Car Hire in Coronado](https://www.expedia.co.uk/Sportscar-Car-Rentals-In-Coronado.d5917-tSportscar.Car-Rental-Guide-Class) - [Sports Car Car Hire in Del Mar](https://www.expedia.co.uk/Sportscar-Car-Rentals-In-Del-Mar.d7626-tSportscar.Car-Rental-Guide-Class) - [Sports Car Car Hire in San Diego Coast](https://www.expedia.co.uk/Sportscar-Car-Rentals-In-San-Diego-Coast.d553248633966884021-tSportscar.Car-Rental-Guide-Class) - [Sports Car Car Hire in San Diego County](https://www.expedia.co.uk/Sportscar-Car-Rentals-In-San-Diego-County.d178304-tSportscar.Car-Rental-Destination-Class) - [Sports Car Car Hire near San Diego Intl.](https://www.expedia.co.uk/Sportscar-Car-Rentals-In-San-Diego-Intl.d5128531-tSportscar.Car-Rental-Guide-Class) - [Standard Car Hire near San Diego Intl.](https://www.expedia.co.uk/Standard-Car-Rentals-In-San-Diego-Intl.d5128531-tStandard.Car-Rental-Guide-Class) - [People Carrier Car Hire in Asian Pacific Thematic Historic District](https://www.expedia.co.uk/Van-Car-Rentals-In-Asian-Pacific-Thematic-Historic-District.d713883578777456640-tVan.Car-Rental-Guide-Class) - [People Carrier Car Hire in Dana Point](https://www.expedia.co.uk/Van-Car-Rentals-In-Dana-Point.d6752-tVan.Car-Rental-Guide-Class) - [People Carrier Car Hire near San Diego Intl.](https://www.expedia.co.uk/Van-Car-Rentals-In-San-Diego-Intl.d5128531-tVan.Car-Rental-Guide-Class) - [People Carrier Car Hire in San Diego](https://www.expedia.co.uk/Van-Car-Rentals-In-San-Diego.d3073-tVan.Car-Rental-Guide-Class)