Title: Enterprise Car Hire Deals in Southern Illinois | Expedia.co.uk ![](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Enterprise Car Hire in Southern Illinois Photo by Southernmost Illinois Tourism Bureau [Become a member for free](https://expedia.co.uk/member-price?rfrr=TG.CM) and get more than just a booking discount. Members also earn points towards their next trip. Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more. Enjoy maximum flexibility with penalty-free cancellation on most car rentals. ## Find Cheap Enterprise Rental Deals in Southern Illinois \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Southern Illinois [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=22/09/2025&date2=24/09/2025&crfrr=defaultFlex&SearchType=Place&selVen=[%2215%22]) ## Everything you need to know about Enterprise car hire in Southern Illinois #### What are the advantages of hiring a car from Enterprise in Southern Illinois with Expedia.co.uk? You can find incredible deals on Expedia.co.uk in Southern Illinois, Illinois with Enterprise at customisable pick-up and drop-off locations. Enjoy a large stock of cars, special discounts and fantastic customer service. #### How can I get the best deals from Enterprise in Southern Illinois? Discover great car hire companies at the best price on Expedia.co.uk with Enterprise in Southern Illinois. Enterprise offers a variety of car types, and pricing varies based on travel dates and pick-up location. Economy or compact cars are generally cheaper. To see other great deals from all our suppliers, check out our main page for car hire in Southern Illinois. #### Where are the Enterprise pick-up locations in Southern Illinois? There are Enterprise locations throughout Southern Illinois. Choose the most convenient car hire location for you. The largest selection of vehicles is generally available at the airport or in the city centre. Local branches ensure that you won’t need to travel too far. Scroll down to see location options for the area. #### Which types of cars can I hire from Enterprise in Southern Illinois? Enterprise has lots of different cars. While stock varies between Southern Illinois Enterprise car hire locations, you’ll find a large selection to suit your needs. Find options for a range of budgets and preferences. Choose from cheap, luxury and mid-range SUVs, convertibles, hybrids, sports cars, saloons and more. Wherever you’re going, Expedia.co.uk will help you get there. #### What is the cancellation policy? Enterprise has different cancellation policies for different cars. Some bookings are free to cancel, while others may be non-refundable. Be sure to understand the terms of your deal before booking. We recommend using the “Free cancellation” filter during your search to stay flexible. #### Why is Expedia.co.uk the best place to book my hire car? Where you book matters. Expedia.co.uk offers a huge selection and the best deals on cars in the area. We reward you with points back on every booking and ensure that you get the right vehicle for the best price. You can also book flights or Southern Illinois hotels with your car hire, and get a holiday package in Southern Illinois for less. ## Enterprise Car Hire Information | Car Supplier: | Enterprise | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ### Find Enterprise Car Pickup Locations near Southern Illinois > - [Enterprise car hire in Chesterfield](https://expedia.co.uk/Enterprise-Car-Rentals-In-Chesterfield.d9530-c15.Car-Rental-Guide-Suppliers) > - [Enterprise car hire in Ozarks](https://expedia.co.uk/Enterprise-Car-Rentals-In-Ozarks.d6209951-c15.Car-Rental-Guide-Suppliers) > - [Enterprise car hire in Arnold](https://expedia.co.uk/Enterprise-Car-Rentals-In-Arnold.d177608-c15.Car-Rental-Guide-Suppliers) ### Find Popular Airports close to Southern Illinois > - [Car hire at Lambert-St. Louis Intl. Airport (STL)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lambert-St-Louis-Intl.d5002323.Car-Hire-Guide) > - [Car hire at Cape Girardeau Municipal Airport (CGI)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) > - [Car hire at Decatur Airport (DEC)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Decatur.d6027335.Car-Hire-Guide) > - [Car hire at Evansville Regional Airport (EVV)](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Evansville-Regional.d6027729.Car-Hire-Guide) ### Car Hire Suppliers at Southern Illinois > - [Alamo Rent A Car car hire in Southern Illinois](https://expedia.co.uk/Alamo-Rent-A-Car-Car-Rentals-In-Southern-Illinois.d6233859-c6.Car-Rental-Guide-Suppliers) > - [Budget car hire in Southern Illinois](https://expedia.co.uk/Budget-Car-Rentals-In-Southern-Illinois.d6233859-c39.Car-Rental-Guide-Suppliers) > - [Enterprise car hire in Southern Illinois](https://expedia.co.uk/Enterprise-Car-Rentals-In-Southern-Illinois.d6233859-c15.Car-Rental-Guide-Suppliers) > - [Hertz car hire in Southern Illinois](https://expedia.co.uk/Hertz-Car-Rentals-In-Southern-Illinois.d6233859-c40.Car-Rental-Guide-Suppliers) > - [Thrifty Car Rental car hire in Southern Illinois](https://expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-Southern-Illinois.d6233859-c45.Car-Rental-Guide-Suppliers) > - [Avis car hire in Southern Illinois](https://expedia.co.uk/Avis-Car-Rentals-In-Southern-Illinois.d6233859-c41.Car-Rental-Guide-Suppliers) > - [Dollar Rent A Car car hire in Southern Illinois](https://expedia.co.uk/Dollar-Rent-A-Car-Car-Rentals-In-Southern-Illinois.d6233859-c43.Car-Rental-Guide-Suppliers) > - [Sixt car hire in Southern Illinois](https://expedia.co.uk/Sixt-Car-Rentals-In-Southern-Illinois.d6233859-c35.Car-Rental-Guide-Suppliers) > - [National car hire in Southern Illinois](https://expedia.co.uk/National-Car-Rental-Car-Rentals-In-Southern-Illinois.d6233859-c42.Car-Rental-Guide-Suppliers) > - [Fox Rental Cars car hire in Southern Illinois](https://expedia.co.uk/Fox-Rental-Cars-Car-Rentals-In-Southern-Illinois.d6233859-c19.Car-Rental-Guide-Suppliers) > - [Payless car hire in Southern Illinois](https://expedia.co.uk/Payless-Car-Rentals-In-Southern-Illinois.d6233859-c38.Car-Rental-Guide-Suppliers) > - [Europcar car hire in Southern Illinois](https://expedia.co.uk/Europcar-Car-Rentals-In-Southern-Illinois.d6233859-c14.Car-Rental-Guide-Suppliers) ### Car Types in Southern Illinois > - [Mini car hire in Southern Illinois](https://expedia.co.uk/Mini-Car-Rentals-In-Southern-Illinois.d6233859-tMini.Car-Rental-Guide-Class) > - [Economy car hire in Southern Illinois](https://expedia.co.uk/Economy-Car-Rentals-In-Southern-Illinois.d6233859-tEconomy.Car-Rental-Guide-Class) > - [Compact car hire in Southern Illinois](https://expedia.co.uk/Compact-Car-Rentals-In-Southern-Illinois.d6233859-tCompact.Car-Rental-Guide-Class) > - [Midsize car hire in Southern Illinois](https://expedia.co.uk/Midsize-Car-Rentals-In-Southern-Illinois.d6233859-tMidsize.Car-Rental-Guide-Class) > - [Standard car hire in Southern Illinois](https://expedia.co.uk/Standard-Car-Rentals-In-Southern-Illinois.d6233859-tStandard.Car-Rental-Guide-Class) > - [Fullsize car hire in Southern Illinois](https://expedia.co.uk/Fullsize-Car-Rentals-In-Southern-Illinois.d6233859-tFullsize.Car-Rental-Guide-Class) > - [Premium car hire in Southern Illinois](https://expedia.co.uk/Premium-Car-Rentals-In-Southern-Illinois.d6233859-tPremium.Car-Rental-Guide-Class) > - [Luxury car hire in Southern Illinois](https://expedia.co.uk/Luxury-Car-Rentals-In-Southern-Illinois.d6233859-tLuxury.Car-Rental-Guide-Class) > - [Convertible car hire in Southern Illinois](https://expedia.co.uk/Convertible-Car-Rentals-In-Southern-Illinois.d6233859-tConvertible.Car-Rental-Guide-Class) > - [Minivan car hire in Southern Illinois](https://expedia.co.uk/Minivan-Car-Rentals-In-Southern-Illinois.d6233859-tMinivan.Car-Rental-Guide-Class) > - [Van car hire in Southern Illinois](https://expedia.co.uk/Van-Car-Rentals-In-Southern-Illinois.d6233859-tVan.Car-Rental-Guide-Class) > - [SUV car hire in Southern Illinois](https://expedia.co.uk/SUV-Car-Rentals-In-Southern-Illinois.d6233859-tSUV.Car-Rental-Guide-Class) > - [Pickup car hire in Southern Illinois](https://expedia.co.uk/Pickup-Car-Rentals-In-Southern-Illinois.d6233859-tPickup.Car-Rental-Guide-Class) > - [Sportscar car hire in Southern Illinois](https://expedia.co.uk/Sportscar-Car-Rentals-In-Southern-Illinois.d6233859-tSportscar.Car-Rental-Guide-Class) Heading to Southern Illinois? Explore Southern Illinois with Expedia's Travel Guides to find the best hotels, holiday packages, car hire deals and more! [Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Hotels](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Southern Illinois Holiday Rentals](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ### Expedia's Latest Trends Hotels - [The Loop Cheap Hotels](https://expedia.co.uk/The-Loop-Chicago-Hotels-Budget-Hotels.0-n800024-0-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Anna Maria Island Accommodation](https://expedia.co.uk/Anna-Maria-Island-Hotels.d553248622847118534.Travel-Guide-Hotels) - [Maui Accommodation](https://expedia.co.uk/Maui-Hotels.d180073.Travel-Guide-Hotels) - [Cape Cod Accommodation](https://expedia.co.uk/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels) - [Martha's Vineyard Accommodation](https://expedia.co.uk/Marthas-Vineyard-Hotels.d6047691.Travel-Guide-Hotels) - [Hamptons Accommodation](https://expedia.co.uk/Hamptons-Hotels.d6056452.Travel-Guide-Hotels) - [Hotels in The Loop](https://expedia.co.uk/The-Loop-Chicago-Hotels.0-n800024-0.Travel-Guide-Filter-Hotels) - [Hotels in Downtown Chicago](https://expedia.co.uk/Downtown-Chicago-Chicago-Hotels.0-n6350699-0.Travel-Guide-Filter-Hotels) Flights - [Flights to PHF](https://expedia.co.uk/Cheap-Flights-To-Norfolk-Virginia-Beach.d602904.Travel-Guide-Flights) - [Flights to OGG](https://expedia.co.uk/Cheap-Flights-To-Maui.d180073.Travel-Guide-Flights) - [Flights to ACK](https://expedia.co.uk/Cheap-Flights-To-Marthas-Vineyard.d6047691.Travel-Guide-Flights) - [Flights to ORF](https://expedia.co.uk/Cheap-Flights-To-Outer-Banks.d602135.Travel-Guide-Flights) - [Flights to ACK](https://expedia.co.uk/Cheap-Flights-To-Nantucket-Island.d6047676.Travel-Guide-Flights) - [Flights to KOA](https://expedia.co.uk/Cheap-Flights-To-Hawaii-Island.d180074.Travel-Guide-Flights) - [Flights to ORD](https://expedia.co.uk/Cheap-Flights-To-OHare-Intl.d4477519.Travel-Guide-Flights) Cars - [Car rental in Downtown Chicago](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-Chicago.d6350699.Car-Hire-Guide) - [Car rental in Kauai](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Kauai.d180075.Car-Hire-Guide) - [Car rental in Chicago](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-OHare-Intl.d4477519.Car-Hire-Guide) Activities - [Things to do in South Florida](https://expedia.co.uk/Things-To-Do-In-South-Florida.d6233792.Travel-Guide-Activities) Packages - [Trips to Cape Cod](https://expedia.co.uk/Cape-Cod.d180061.Holidays-City-Breaks) - [Six Flags Great America](https://expedia.co.uk/Six-Flags-Great-America-Chicago.d6023396.Attraction) - [Trips to Downtown Chicago](https://expedia.co.uk/Downtown-Chicago.d6350699.Holidays-City-Breaks) - [Trips to Maui](https://expedia.co.uk/Maui.d180073.Holidays-City-Breaks) - [Robert Wadlow Statue](https://expedia.co.uk/Robert-Wadlow-Statue-Alton.d553248635919228114.Attraction) - [Trips to Hamptons](https://expedia.co.uk/Hamptons.d6056452.Holidays-City-Breaks) - [Trips to Niagara Falls - Western New York](https://expedia.co.uk/Niagara-Falls-Western-New-York.d6056506.Holidays-City-Breaks) General - [Visit Palatine](https://expedia.co.uk/Palatine.dx9059) - [Visit The Loop](https://expedia.co.uk/Chicago-The-Loop.dx800024) - [Visit Downtown Chicago](https://expedia.co.uk/Chicago-Downtown-Chicago.dx6350699) - [Visit Oak Park](https://expedia.co.uk/Oak-Park.dx9228) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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