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Our top choices for Downtown Clayton hotels

1. Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
2. AC Hotel St. Louis Clayton
AC Hotel St. Louis Clayton
3. Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
4. Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
5. The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
7. The Knight Center at Washington University
The Knight Center at Washington University
8. Courtyard by Marriott St. Louis Brentwood
Courtyard by Marriott St. Louis Brentwood
9. Drury Plaza Hotel St. Louis Brentwood
Drury Plaza Hotel St. Louis Brentwood
10. Moonrise Hotel
Moonrise Hotel
11. The Cheshire
The Cheshire
12. The West End
The West End
13. SpringHill Suites St. Louis Brentwood
SpringHill Suites St. Louis Brentwood
14. The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
15. Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest Park
16. Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
17. Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
18. Hyatt Select St. Louis Airport
Hyatt Select St. Louis Airport
19. Drury Inn & Suites St. Louis Forest Park
Drury Inn & Suites St. Louis Forest Park
20. Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The ArchCompare popular hotels in Downtown Clayton
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() AC Hotel St. Louis Clayton | 9.2 Wonderful 423 reviews | View | ||||||
![]() The Ritz-Carlton, St. Louis | 9.2 Wonderful 587 reviews | View | ||||||
![]() Clayton Plaza Hotel & Extended Stay | 8.8 Excellent 3,515 reviews | View | ||||||
![]() Le Méridien St. Louis Clayton | 8.8 Excellent 801 reviews | View | ||||||
![]() Seven Gables, St. Louis West, a Tribute Portfolio Hotel | 8.4 Very good 603 reviews | View |
Hotels recommended for families in Downtown Clayton

Where to stay in Downtown Clayton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Top Downtown Clayton Hotel Reviews

Pear Tree Inn St. Louis Near Union Station
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