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Our top choices for Downtown Clayton hotels

1. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Downtown Clayton
8.8 out of 10, Excellent, (3,515 reviews)
"Great location, nice rooms!"
United States
Martha
The price is £91
includes taxes & fees
8 Nov - 9 Nov
Clayton Plaza Hotel & Extended Stay

2. AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
2.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (423 reviews)
"Great stay"
United States
anthony
The price is £112
includes taxes & fees
8 Nov - 9 Nov
AC Hotel St. Louis Clayton

3. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Downtown Clayton
8.8 out of 10, Excellent, (801 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is £133
includes taxes & fees
8 Nov - 9 Nov
Le Méridien St. Louis Clayton

4. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Downtown Clayton
8.4 out of 10, Very good, (603 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
United States
Jennifer
The price is £137
includes taxes & fees
8 Nov - 9 Nov
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (587 reviews)
"Incredible stay! Loved the room, the staff were great, and the amenities were amazing! Definitely recommend staying here!"
United States
Kennedy
The price is £494
includes taxes & fees
27 Nov - 28 Nov
The Ritz-Carlton, St. Louis

6. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
0.4 mi from Downtown Clayton
8.8 out of 10, Excellent, (1,000 reviews)
"Great location - staff was awesome!"
United States
Kevin
The price is £104
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

7. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
1.4 mi from Downtown Clayton
9.4 out of 10, Exceptional, (717 reviews)
"We will absolutely stay here again when traveling to Wash U. Great hotel!"
United States
jeffrey
The price is £104
includes taxes & fees
28 Nov - 29 Nov
The Knight Center at Washington University

8. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
1.4 mi from Downtown Clayton
9.4 out of 10, Exceptional, (912 reviews)
"Beautiful accommodations! Helpful staff😊"
United States
Anna
The price is £107
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott St. Louis Brentwood

9. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
1.5 mi from Downtown Clayton
9.6 out of 10, Exceptional, (1,006 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is £113
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Brentwood

10. Moonrise Hotel

Moonrise Hotel
4.0 star property
2.1 mi from Downtown Clayton
9.0 out of 10, Wonderful, (2,049 reviews)
"Cool hotel!"
United States
Rebecca
The price is £132
includes taxes & fees
18 Nov - 19 Nov
Moonrise Hotel

11. The Cheshire

The Cheshire
4.0 star property
1.9 mi from Downtown Clayton
8.8 out of 10, Excellent, (1,000 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is £132
includes taxes & fees
29 Nov - 30 Nov
The Cheshire

12. The West End

The West End
2.0 star property
Central West End, 4.8 mi from Downtown Clayton
8.6 out of 10, Excellent, (708 reviews)
"Excellent value, location. I'd stay here again."
United States
Trevor
The price is £88
includes taxes & fees
5 Nov - 6 Nov
The West End

13. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
1.8 mi from Downtown Clayton
9.0 out of 10, Wonderful, (1,000 reviews)
"Staff was very friendly and rooms were clean."
United States
Aaron
The price is £110
includes taxes & fees
22 Nov - 23 Nov
SpringHill Suites St. Louis Brentwood

14. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 3.9 mi from Downtown Clayton
9.2 out of 10, Wonderful, (1,006 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is £153
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis

15. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 3.3 mi from Downtown Clayton
9.4 out of 10, Exceptional, (1,000 reviews)
"Well maintained, great staff and very clean."
United States
Greg
The price is £114
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites St. Louis at Forest Park

16. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
6.5 mi from Downtown Clayton
9.4 out of 10, Exceptional, (3,347 reviews)
"Great stay for airport access"
United States
Rebecca
The price is £79
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn St. Louis Airport

17. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 8.2 mi from Downtown Clayton
9.6 out of 10, Exceptional, (3,828 reviews)
"Very nice hotel.. love that are arch is right behind it.."
United States
Nicole
The price is £125
includes taxes & fees
10 Nov - 11 Nov
Drury Plaza Hotel St. Louis at the Arch

18. Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
6 mi from Downtown Clayton
9.2 out of 10, Wonderful, (1,014 reviews)
"Loved my stay"
United States
Thadora
The price is £101
includes taxes & fees
11 Nov - 12 Nov
Hyatt Select St. Louis Airport

19. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
3.4 mi from Downtown Clayton
9.4 out of 10, Exceptional, (1,027 reviews)
"Loved staying there!"
United States
Tammy
The price is £117
includes taxes & fees
10 Nov - 11 Nov
Drury Inn & Suites St. Louis Forest Park

20. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 8.2 mi from Downtown Clayton
8.6 out of 10, Excellent, (4,386 reviews)
"Great location and great place to visit"
United States
Tracy
The price is £110
includes taxes & fees
26 Nov - 27 Nov
Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Downtown Clayton

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A rooftop terrace with modern outdoor seating, a fire pit, and a view of the cityscape.
AC Hotel St. Louis Clayton
2.0 star property
9.2
Wonderful
423 reviews
View
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
The Ritz-Carlton, St. Louis
5.0 star property
9.2
Wonderful
587 reviews
View
The Clayton Plaza Hotel sign with a stone wall and plants in front.
Clayton Plaza Hotel & Extended Stay
3.5 star property
8.8
Excellent
3,515 reviews
View
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
Le Méridien St. Louis Clayton
4.0 star property
8.8
Excellent
801 reviews
View
A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
8.4
Very good
603 reviews
View

Hotels recommended for families in Downtown Clayton

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top Downtown Clayton Hotel Reviews

Frequently asked questions

What other neighbourhoods are similar to Downtown Clayton?
Other neighbourhoods similar to Downtown Clayton include the Central West End and the Delmar Loop, both offering a sophisticated urban experience with a focus on quality and convenience.

The Central West End, located just east of Forest Park, is known for its elegant tree-lined streets, historic architecture, and a mix of upscale boutiques, art galleries, and restaurants, particularly along Maryland Plaza and Euclid Avenue. It's a well-connected area with easy access to public transport and major attractions.

For solo travellers or couples who appreciate a lively option with independent shops and diverse dining, the Delmar Loop is an excellent choice. This area, centred around Delmar Boulevard, is famous for its independent music venues, unique shops, and a wide array of international eateries.
What are the best hotels in Downtown Clayton that travellers recommend?
Three of the best hotels in Downtown Clayton that travellers recommend are Le Méridien St. Louis Clayton, AC Hotel St. Louis Clayton, and Residence Inn By Marriott St. Louis Clayton.

The 4-star Le Méridien St. Louis Clayton, with an 8.8 rating, is praised for its comfortable and clean rooms, as well as its amazing staff and gym. Guests also appreciate the great location and easy valet parking. This hotel offers premium bedding, air conditioning, and an outdoor pool with sun loungers. It is conveniently located 2.3 km from Washington University in St. Louis and 1.6 km from Saint Louis Galleria Mall.

The 3-star AC Hotel St. Louis Clayton has an impressive 9.2 rating, with guests frequently commending the exceptionally friendly and helpful staff. This hotel features a roll-in shower and accessible fitness facilities. It is just 1.4 km from Saint Louis Galleria Mall.

Another highly-rated option is the 3-star Residence Inn By Marriott St. Louis Clayton, also with a 9.2 rating. Guests highlight the nice, clean rooms, the friendly and helpful staff, and the excellent service. The complimentary full breakfast is also a popular feature. The hotel provides secured and covered valet parking and is located 1.8 km from Saint Louis Galleria Mall.
What are the best family hotels in Downtown Clayton?
For family-friendly hotels in Downtown Clayton, consider Le Méridien St. Louis Clayton, AC Hotel St. Louis Clayton, Homewood Suites by Hilton St Louis - Galleria, or Courtyard by Marriott St. Louis Brentwood.

The 4-star Le Méridien St. Louis Clayton, with a rating of 8.8, is praised for its comfortable and clean rooms, amazing gym, and nice staff. Families will appreciate amenities such as a pool, free rollaway extra beds, connecting rooms, free cribs, and sofa beds. It is conveniently located 1.6 km from Saint Louis Galleria Mall.

The 3-star AC Hotel St. Louis Clayton, rated 9.2, stands out for its very friendly and helpful staff. It offers sofa beds, free cribs, and connecting rooms, making it suitable for families. The hotel also has fitness facilities. Saint Louis Galleria Mall is 1.4 km away.

Homewood Suites by Hilton St Louis - Galleria, a 3-star hotel with an 8.0 rating, offers spacious and clean rooms, along with friendly and helpful staff. Guests particularly enjoy the good, free full breakfast and the convenient and easy parking. Families will benefit from the pool, sofa beds, and connecting rooms. The hotel is very close to Saint Louis Galleria Mall, just 0.4 km away.

Another excellent option is the 3-star Courtyard by Marriott St. Louis Brentwood, which has an outstanding 9.4 rating. This hotel is known for its cosy and clean rooms, great pillows, and extremely helpful staff. It provides free WiFi, free self-parking, free rollaway extra beds, free cribs, and connecting rooms, all adding to a comfortable family stay. It is 1.5 km from Saint Louis Galleria Mall.
What are the best 5-star hotels in Downtown Clayton?
For a luxurious 5-star experience in Downtown Clayton, The Ritz-Carlton, St. Louis is an excellent choice.

This highly-rated 5-star hotel boasts an impressive 9.2 review rating. Guests can expect premium bedding and designer toiletries for a comfortable stay. The hotel offers convenient covered valet parking and couples dining options. Its location also provides easy access to the Saint Louis Galleria Mall, which is just 2.1 km away.
What are the best spa hotels in Downtown Clayton?
For a top-tier spa experience in Downtown Clayton, The Ritz-Carlton, St. Louis is an exceptional choice.

This 5-star hotel, with an impressive 9.2 rating, offers a range of spa services designed for ultimate relaxation. Guests can indulge in aromatherapy treatments, body treatments, hot stone massages, body wraps, body scrubs, and deep tissue massages. The on-site spa also provides facial treatments and dedicated massage treatment rooms. For those looking to combine relaxation with retail therapy, the Saint Louis Galleria Mall is conveniently located just 2.1 km away.
What hotels in Downtown Clayton offer free breakfast?
For hotels in Downtown Clayton that offer complimentary breakfast, consider the Drury Inn & Suites St. Louis Brentwood, Hampton Inn & Suites Clayton/St. Louis-Galleria Area, Residence Inn By Marriott St. Louis Clayton, Clayton Plaza Hotel & Extended Stay, or Homewood Suites by Hilton St Louis - Galleria.

The 3-star Drury Inn & Suites St. Louis Brentwood, with an outstanding 9.6 rating, provides a great free buffet breakfast and complimentary drinks. Guests frequently praise the friendly staff and the clean, beautiful rooms.

Another excellent choice is the 3-star Hampton Inn & Suites Clayton/St. Louis-Galleria Area, rated 9.0. This hotel offers a free continental breakfast and suites, with guests often highlighting the clean, quiet rooms and helpful staff.

The 3-star Residence Inn By Marriott St. Louis Clayton, rated 9.2, also provides a free full breakfast daily. It is known for its nice, clean rooms and friendly, helpful staff who offer excellent service.

The 3.5-star Clayton Plaza Hotel & Extended Stay, with an 8.8 rating, offers a free full breakfast and is conveniently located just 2.4 km from Washington University in St. Louis. Guests appreciate the comfortable rooms and fantastic location.

Finally, the 3-star Homewood Suites by Hilton St Louis - Galleria, rated 8.0, offers a free full buffet breakfast. This hotel features spacious, clean rooms and a convenient location, with guests often commending the friendly staff.
What are the top pet-friendly hotels in Downtown Clayton?
For top pet-friendly hotels in Downtown Clayton, consider Le Méridien St. Louis Clayton or The Ritz-Carlton, St. Louis.

The 4-star Le Méridien St. Louis Clayton, with an 8.8 rating, warmly welcomes pets, specifically dogs. Guests frequently praise its comfortable and clean rooms, amazing gym, and excellent location. It is also conveniently located 2.3 km from Washington University in St. Louis and 1.6 km from Saint Louis Galleria Mall.

Another excellent choice is the 5-star The Ritz-Carlton, St. Louis, which boasts an impressive 9.2 rating. This hotel permits both dogs and cats and provides food and water bowls. It offers premium bedding and designer toiletries, along with valet parking. It is situated 1.9 km from Washington University in St. Louis.
What are the best budget hotels in Downtown Clayton?
For excellent budget hotels in Downtown Clayton, consider the Drury Inn & Suites St. Louis Brentwood, the Residence Inn By Marriott St. Louis Clayton, or the Courtyard by Marriott St. Louis Brentwood.

The 3-star Drury Inn & Suites St. Louis Brentwood, with an impressive 9.6 rating, offers a fantastic experience with friendly staff, a great free breakfast, and beautiful, clean rooms. Guests also appreciate the free drinks and convenient location.

Another highly-rated option is the 3-star Residence Inn By Marriott St. Louis Clayton, boasting a 9.2 rating. This hotel provides nice, clean rooms, helpful staff, and excellent service. Its complimentary full breakfast and great amenities are frequently praised by guests.

The 3-star Courtyard by Marriott St. Louis Brentwood, rated 9.4, is also a superb choice. It features cosy, clean rooms and a convenient location. Guests often highlight the helpful staff and the plentiful, convenient parking.
What are the most romantic hotels in Downtown Clayton for couples?
For couples seeking a romantic stay in Downtown Clayton, The Ritz-Carlton, St. Louis and Seven Gables, St. Louis West, a Tribute Portfolio Hotel are excellent choices.

The 5-star Ritz-Carlton, St. Louis, with a superb 9.2 rating, offers a luxurious experience great for couples. It features couples dining options, premium bedding, and designer toiletries for a truly indulgent stay. Guests can also benefit from valet parking, including covered options, and enjoy air-conditioned comfort.

Another wonderful option is the 3.5-star Seven Gables, St. Louis West, a Tribute Portfolio Hotel, which has an 8.4 rating. This hotel is praised by customers for its clean, large rooms and top customer service. Couples will appreciate the couples dining, premium bedding with Egyptian cotton sheets, and champagne service. It also provides designer toiletries and bathrobes, and its restaurant offers garden views. The hotel is conveniently located in a shopping district, with the Saint Louis Galleria Mall just 1.9 km away.
What are the best hotels in Downtown Clayton near Saint Louis Galleria Mall?
For hotels in Downtown Clayton near Saint Louis Galleria Mall, consider the Drury Inn & Suites St. Louis Brentwood and the AC Hotel St. Louis Clayton.

The 3-star Drury Inn & Suites St. Louis Brentwood, with an impressive 9.6 rating, is conveniently located just 0.8 kilometres from Saint Louis Galleria Mall. Guests frequently praise the friendly staff, the great free breakfast buffet, and the beautiful, clean rooms. The hotel also offers free WiFi, free toiletries, and complimentary self-parking.

Another excellent option is the 3-star AC Hotel St. Louis Clayton, rated 9.2, which is 1.4 kilometres from the mall. It offers a sofa bed and free cribs, making it suitable for families. Guests often highlight the helpful and friendly staff, and the hotel provides fitness facilities including an accessible fitness centre.
When is the best time to go to Downtown Clayton?
The best time to visit Downtown Clayton is generally during the spring (April to June) and autumn (September to November) months.

These seasons offer pleasant weather, with mild temperatures that are ideal for exploring the area's shops, restaurants, and parks on foot. You'll find fewer extreme temperatures compared to the hot and humid summer or the cold winter months, making outdoor activities more enjoyable.

For those planning to attend outdoor events or dine al fresco, spring and autumn provide comfortable conditions. Many local establishments have outdoor seating, and the moderate weather allows you to take advantage of these without discomfort.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Downtown Clayton.
How much is the nightly rate at a Downtown Clayton hotel?
Hotel prices in Downtown Clayton often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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