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Our top choices for Downtown Clayton hotels

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Le Méridien St. Louis Clayton
Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
AC Hotel St. Louis Clayton
AC Hotel St. Louis Clayton
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
Motel 6 Hazelwood, MO
Motel 6 Hazelwood, MO
Courtyard by Marriott St. Louis St. Peters
Courtyard by Marriott St. Louis St. Peters
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
Embassy Suites by Hilton St. Louis Downtown
Embassy Suites by Hilton St. Louis Downtown
Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. Peters
The Principal Hotel
The Principal Hotel
Hilton St. Louis Frontenac
Hilton St. Louis Frontenac
Missouri Athletic Club
Missouri Athletic Club
SpringHill Suites St. Louis Brentwood
SpringHill Suites St. Louis Brentwood
Courtyard by Marriott St. Louis Downtown/Convention Center
Courtyard by Marriott St. Louis Downtown/Convention Center
Fairfield Inn & Suites by Marriott St. Louis Downtown
Fairfield Inn & Suites by Marriott St. Louis Downtown
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
Hampton Inn By Hilton St Louis Airport
Hampton Inn By Hilton St Louis AirportWhere to stay in Downtown Clayton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
Top Downtown Clayton Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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