Downtown Clayton Holidays

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Your Downtown Clayton Holiday

Your next great adventure beckons with a holiday package to Downtown Clayton. Relaxation, entertainment and nothing but great times — you're bound to find it in this neighbourhood. Some top nearby attractions to see during your trip to Downtown Clayton include St. Louis Zoo, St. Louis Art Museum and Washington University in St. Louis. Expedia can help turn your dream Downtown Clayton holiday into reality, no matter your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
  • Terrace/patio
    Aug 5 - Aug 11

    Angad Arts Hotel St. Louis, Tapestry Collection by Hilton + Flight

    Grand Center
    6 nights
    4.0 star property
    8.8/10 - Excellent (1,059 reviews)
    Return • Glasgow (GLA) - St. Louis (STL)
    GLA - STL • 2 stops STL - GLA • 2 stops
    £1,545
    £1,374
    per traveller
    found 1 day ago
    Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
  • Outdoor dining
    Aug 5 - Aug 11

    Osceola + Flight

    Mount Pleasant
    6 nights
    2.0 star property
    Return • Glasgow (GLA) - St. Louis (STL)
    GLA - STL • 2 stops STL - GLA • 2 stops
    £4,283
    £3,591
    per traveller
    found 1 day ago
    Osceola
  • Luxury House, 5 Bedrooms, Non Smoking, Pets allowed | Private kitchen
    Aug 5 - Aug 11

    Nebraska + Flight

    Benton Park West
    6 nights
    2.0 star property
    Return • Glasgow (GLA) - St. Louis (STL)
    GLA - STL • 2 stops STL - GLA • 2 stops
    £3,141
    £2,697
    per traveller
    found 1 day ago
    Nebraska
  • Gastropub
    Aug 5 - Aug 11

    The Cheshire + Flight

    Richmond Heights
    6 nights
    4.0 star property
    8.8/10 - Excellent (1,005 reviews)
    "Two stars.. not even"
    Reviewed May 17, 2026
    Return • Glasgow (GLA) - St. Louis (STL)
    GLA - STL • 2 stops STL - GLA • 2 stops
    £1,652
    £1,427
    per traveller
    found 1 day ago
    The Cheshire
  • Courtyard
    Aug 5 - Aug 11

    The Knight Center at Washington University + Flight

    St. Louis
    6 nights
    2.5 star property
    9.4/10 - Exceptional (548 reviews)
    "The breakfast was very reasonably priced and offered vegetarian/vegan options."
    Reviewed May 17, 2026
    Return • Glasgow (GLA) - St. Louis (STL)
    GLA - STL • 2 stops STL - GLA • 2 stops
    £1,631
    £1,423
    per traveller
    found 1 day ago
    The Knight Center at Washington University

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Clayton
Downtown St. Louis

Downtown St. Louis

3 out of top 10 points of interest in this area
4.5/5(18 area reviews)

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Find hotels in Downtown St. Louis

Top hotels in Downtown Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £86 per night from 7 Jun to 8 Jun
£86
7 Jun - 8 Jun
includes taxes & fees
8.8/10 Excellent! (3,202 reviews)
"An event was occurring in the ballroom right above our room. It was after 9 pm and the room was bouncing and creaking with the dancing and hopping up and down, enough to feel like motion sickness. We requested to be moved and the staff person said they were fully booked, and was rude about the situation. ..."

Reviewed on 18 May 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £133 per night from 27 May to 28 May
£133
27 May - 28 May
includes taxes & fees
Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
Fully refundableReserve now, pay when you stay
The price is £437 per night from 24 May to 25 May
£437
24 May - 25 May
includes taxes & fees
9.2/10 Wonderful! (568 reviews)
"No swimming pool.....whole experience didn't seem top level"

Reviewed on 10 May 2026

The Ritz-Carlton, St. Louis
See all 1,865 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Downtown Clayton travel package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in Downtown Clayton from just . And the more you bundle, the more you save. The getaway of your dreams has never been more affordable.
If I'm not able to travel, can I cancel my Downtown Clayton travel package?
We totally understand — the universe can throw the odd curveball. If you've locked in a Downtown Clayton travel package and need to change or cancel it, we can help. It's always worth looking up our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to change your itinerary for free. If it's more than 24 hours, your hotel, airline or car rental company may charge a fee.
How do I get a cheap travel package to Downtown Clayton?
One of the simplest ways to save money (and time) is to bundle your bookings with Expedia. Flights, rental cars, hotels and activities — we've got them all. Select the combination that suits you and watch your savings pile up. We know a travel package is never one-size-fits-all. That's why we offer over 550 airlines and 1,000,000 hotels across the globe, which lets you customize your Downtown Clayton holiday.
Does Expedia offer Book Now, Pay Later Downtown Clayton holidays?
Yes. Expedia has partnered with online lender Klarna to help you conveniently pay for your holiday in instalments. Simply choose the payment plan that suits you best during the checkout process and take the stress out of budgeting for your trip. Remember to bundle your flights, hotel and car hire with Expedia to get the biggest bang for your buck. Browse our flexible payment options below:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that suit all types of budgets, so you can jet away on that well-earned holiday now.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your trip over multiple transactions.
  • Low deposit holidays: When you spot an amazing deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you secure your getaway.

Where should I stay in Downtown Clayton?
Urban adventurers come from all corners of the globe to experience Gateway Arch and Busch Stadium in Downtown Clayton. Book yourself a room within a stone's throw of these popular attractions to make sightseeing a breeze.
What are the top hotels in Downtown Clayton?
If it's your first time in Downtown Clayton, book a room at City Place St. Louis Downtown or Drury Plaza Hotel St. Louis at the Arch. Both offer friendly service and are top options with lots of travellers.
How far in advance should I book my Downtown Clayton holiday?
The earlier, the better. Airlines typically advertise flight tickets nearly 12 months in advance, and this is a great opportunity to score some of the lowest prices. Just been told you should take some holiday time next month? No sweat. Expedia are never short on fantastic bargains to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Downtown Clayton travel package include?
That depends on what type of trip you have in the works. Downtown Clayton holiday deals can include hotels, car rentals and flights. You can mix and match to find the bundle that works for you! You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Downtown Clayton travel package?
You'll save plenty with an Expedia travel package. Bundle your flights, rental cars and hotels and land fantastic discounts. You're not restricted to hotels, though. We have oceanfront condos, city apartments and even castles and houseboats!
Can I choose my airline with a Downtown Clayton Expedia travel package?
Most definitely. Expedia has more than 550 airline partners to select from globally. With all that choice at your fingertips, finding the perfect carrier to whisk you away to Downtown Clayton won't be difficult.

Popular places to visit

Gateway Arch

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
Saint Louis is a City and Urban Center is Missouri with the Iconic Arch

Dome at America’s Center

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art galleries.

Dome at America’s Center

Six Flags St. Louis

Bring the children to Six Flags St. Louis and have a fun-filled day at this theme park in St. Louis. While in this romantic area, you can savour the top-notch restaurants.

Six Flags St. Louis

Things to do

Best of St. Louis Small Group Tour w/ Arch & River Cruise

St. Louis Premium Small Group Tour With Arch & River Cruise

£118
per adult
84% of travellers recommend
St. Louis Premium Small Group Tour With Arch & River Cruise
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

£11
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

£23
per adult
St. Louis Ghost Tour: Sinister Sins & Shadows
See all activities in St. Louis

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.