Title: Top Hotels in Wayne County - Compare Wayne County Hotels | Expedia.co.uk [Holiday Rentals in Wayne County](https://expedia.co.uk/Destinations-In-Wayne-County.d553248635976433836.Holiday-Rental-Destinations)[Wayne County Car Hire](https://expedia.co.uk/Destinations-In-Wayne-County.d553248635976433836.Car-Hire-Destinations)[Wayne County Holidays](https://expedia.co.uk/Wayne-County.d553248635976433836.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/2/a6135d9f1717ada26d9944dd5bb40459.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Kimberly Falk # Find the best Wayne County Hotels ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Wayne County Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Wayne+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433836&latLong=37.127274%2C-90.450114&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=POOL) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Wayne+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433836&latLong=37.127274%2C-90.450114&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&lodging=CABIN) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wayne+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433836&latLong=37.127274%2C-90.450114&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Wayne+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433836&latLong=37.127274%2C-90.450114&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=PETS) ## Check prices for these dates Tonight [25 Sept - 26 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433836&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Sept - 27 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433836&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433836&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976433836&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Wayne County ![Cabin | 5 bedrooms](https://images.trvl-media.com/lodging/115000000/114280000/114277700/114277672/c09183cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114280000/114277700/114277672/c7addad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cabin | 5 bedrooms](https://images.trvl-media.com/lodging/115000000/114280000/114277700/114277672/ec7dbabe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cabin | 5 bedrooms](https://images.trvl-media.com/lodging/115000000/114280000/114277700/114277672/8921c844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sam A Baker State Park Patterson 9.0/10 Wonderful (4) "Pet friendly, great staff. " £98 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Patterson-Hotels-Sam-A-Baker-State-Park.h114277672.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/33adbe32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/4b3fbea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/65f5a89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | 1 bedroom, desk](https://images.trvl-media.com/lodging/115000000/114280000/114278900/114278842/a0649327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Wappapello Williamsville £108 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Williamsville-Hotels-Lake-Wappapello.h114278842.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83550000/83542600/83542551/f8b833bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83550000/83542600/83542551/015ae2ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83550000/83542600/83542551/0db78bcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/84000000/83550000/83542600/83542551/c69717b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clearwater Lake, cabin minutes from Bluff View Marina & boat dock Piedmont 10/10 Exceptional (32) "Beautiful property, I’d recommend to anyone going here to stay here." £103 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Piedmont-Hotels-Minutes-From-Bluff-View-Marina-Clearwater-Lake.h83542551.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/7282fe58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/6b0c4075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, video library](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/2c03a8ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/19000000/18790000/18787500/18787495/6bf61133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Get Away Acres 1/2 mile off highway 60 extra sanitized Ellsinore 10/10 Exceptional (93) "We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!" £104 includes taxes & fees 29 Sept - 30 Sept [](https://www.expedia.co.uk/Ellsinore-Hotels-Get-Away-Acres-12-Mile-Off-Highway-60-Extra-Sanitized.h18787495.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/38000000/37630000/37621800/37621773/fa4c057c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37630000/37621800/37621773/657b6bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Towels, toilet paper](https://images.trvl-media.com/lodging/38000000/37630000/37621800/37621773/330a8913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/38000000/37630000/37621800/37621773/0b5a93a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bluff View Inn and Resort Piedmont 9.6/10 Exceptional (57) "Was very nice, our place had everything we needed, will definitely book with them again " [](https://www.expedia.co.uk/Piedmont-Hotels-Bluff-View-Inn-Resort.h37621773.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/104000000/103900000/103897900/103897888/w591h683x217y0-5f7417c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/104000000/103900000/103897900/103897888/w749h683x137y0-1e741e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/104000000/103900000/103897900/103897888/w1024h461x0y111-b28814f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/104000000/103900000/103897900/103897888/w564h683x230y0-304e7a91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wanderers End Sanctuary Forest Farm & Village Co-op Clubb [](https://www.expedia.co.uk/Wanderers-End-Sanctuary-Forest-Farm-Village-Co-Op.h103897888.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68150000/68143600/68143525/8e057742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/69000000/68150000/68143600/68143525/507ddbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68150000/68143600/68143525/22599817.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68150000/68143600/68143525/03ae2117.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin 2 2 double beds Piedmont 9.2/10 Wonderful (7) "Enjoyed the stay, room was comfortable." [](https://www.expedia.co.uk/Piedmont-Hotels-Clearwater-Lake-Vacation-Rentals.h68143525.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69810000/69804700/69804672/d97b6ea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/70000000/69810000/69804700/69804672/4ebe04c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69810000/69804700/69804672/465ac888.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/70000000/69810000/69804700/69804672/3d5d21be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin 1 queen bed with a separate bedroom with a double bed Piedmont 8.0/10 Very good (4) "It was well located. Very clean. Very convenient. Great communication with host. Very comfortable. " [](https://www.expedia.co.uk/Piedmont-Hotels-Cabin-1-Queen-Bed-With-A-Separate-Bedroom-With-A-Double-Bed.h69804672.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/68000000/67660000/67658600/67658508/0ee98bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/68000000/67660000/67658600/67658508/8a42cd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/68000000/67660000/67658600/67658508/253b41fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/68000000/67660000/67658600/67658508/b08ad35b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabin near Clearwater Lake Piedmont [](https://www.expedia.co.uk/Piedmont-Hotels-Cabin-Near-Clearwater-Lake.h67658508.Hotel-Information) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490500/104490462/f17d3346.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490500/104490462/df1cb523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490500/104490462/8af7269a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/105000000/104500000/104490500/104490462/0e883f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inviting Des Arc Cabin w/ Fire Pit + Deck! Des Arc [](https://www.expedia.co.uk/Des-Arc-Hotels-Inviting-Des-Arc-Cabin-W-Fire-Pit-Deck.h104490462.Hotel-Information) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/3a8929c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/a3e823f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/cadf7b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537900/93537801/d44ed252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'the Lakehouse' Lovely Wappapello Country Home! Wappapello [](https://www.expedia.co.uk/Wappapello-Hotels-Lovely-Wappapello-Country-Home-Near-Lake.h93537801.Hotel-Information) ![Games room](https://images.trvl-media.com/lodging/97000000/96480000/96471100/96471085/e0d65453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun-loungers](https://images.trvl-media.com/lodging/97000000/96480000/96471100/96471085/1f0a7cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/97000000/96480000/96471100/96471085/8f9760a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96480000/96471100/96471085/685de3e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camp Minnow Beach House Wappapello 9.4/10 Exceptional (14) "It was perfect for what we needed!" [](https://www.expedia.co.uk/Wappapello-Hotels-Camp-Minnow-Beach-House.h96471085.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/24000000/23400000/23393400/23393379/9c3e58b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/24000000/23400000/23393400/23393379/4c39a7dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/24000000/23400000/23393400/23393379/5c2ebb8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/24000000/23400000/23393400/23393379/b8dea1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space Wappapello 9.2/10 Wonderful (56) "It was near good fishing and swimming spots and a lovely space to relax " [](https://www.expedia.co.uk/Wappapello-Hotels-14-Mile-To-The-Boat-Launch-Beach-2-Miles-The-Camp-Free-WiFi.h23393379.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/105000000/104010000/104008000/104007913/1b4d511e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, bed sheets](https://images.trvl-media.com/lodging/105000000/104010000/104008000/104007913/783a3117.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104010000/104008000/104007913/80597cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104010000/104008000/104007913/70ebb03e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unplug for a weekend at Lake Wappapello. Williamsville [](https://www.expedia.co.uk/Williamsville-Hotels-Unplug-For-A-Weekend-At-Lake-Wappapello.h104007913.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/118000000/117060000/117056200/117056200/c7e6c015.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117060000/117056200/117056200/dfe7c5c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/118000000/117060000/117056200/117056200/a15b13b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/118000000/117060000/117056200/117056200/310bfb93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp Wappapello 9.4/10 Exceptional (3) "Our stay was awesome. House was very clean and adorable! " [](https://www.expedia.co.uk/Wappapello-Hotels-Lake-Wappapello-2-Bedroom-Home-18-Mile-To-Beach-And-Boat-Ramp.h117056200.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/c3950ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, WiFi](https://images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/01d1c97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/9da4f272.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/90000000/89720000/89711400/89711320/0a3fff5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private lake, beach & hot tub, romantic getaway or family vaca Wappapello 9.8/10 Exceptional (34) "Loved our weekend stay. Beautiful and peaceful. It had everything that we needed . Very nice neighbor man across the lake. " [](https://www.expedia.co.uk/Wappapello-Hotels-Private-Lake.h89711320.Hotel-Information) ![Oven, stovetop](https://images.trvl-media.com/lodging/121000000/120280000/120275000/120274982/0b2bb22c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120275000/120274982/94f1853a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Internet, bed sheets](https://images.trvl-media.com/lodging/121000000/120280000/120275000/120274982/dfb6fa65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120280000/120275000/120274982/a2a17111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy hobby farm cabin under the stars! Greenville [](https://www.expedia.co.uk/Patterson-Hotels-Cozy-Hobby-Farm-Cabin-Under-The-Stars.h120274982.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/7b7b54ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/71aa8e7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/10599a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided Greenville 10/10 Exceptional (4) "Cute, cozy, private getaway that you won't want to leave!" £184 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Secluded-In-The-Woods.h89701234.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/30000000/29630000/29625100/29625011/755f2618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/30000000/29630000/29625100/29625011/fad55195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/30000000/29630000/29625100/29625011/55ca25e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/30000000/29630000/29625100/29625011/d21099ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clearwater Lake and Black River Vacation Home Piedmont 9.4/10 Exceptional (19) "Nice clean property! Comfortable beds plenty of seating. " [](https://www.expedia.co.uk/Piedmont-Hotels-Clearwater-Lake-And-Black-River-Vacation-Home.h29625011.Hotel-Information) ![House (Multiple Bedrooms) | Front of property](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/0d97a5c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/bec5a95e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/d3745899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/100000000/99400000/99391500/99391486/036f729d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious & Secluded Shook Home w/ Private Hot Tub! Lowndes [](https://www.expedia.co.uk/Spacious-Secluded-Shook-Home-W-Private-Hot-Tub.h99391486.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-10&endDate=2025-10-11®ionId=553248635976433836&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Wayne-County.d553248635976433836.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Wayne-County.d553248635976433836.Hotel-Destinations) ## Top Wayne County Hotel Reviews ![Dexter Inn](//images.trvl-media.com/lodging/1000000/860000/856200/856148/4768517d_y.jpg) ### Dexter Inn 10/10 Excellent "Been a good stay every night" [](https://expedia.co.uk/Sikeston-Hotels-Dexter-Inn.h856148.Hotel-Information) ![Drury Inn & Suites Poplar Bluff](//images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164_y.jpg) ### Drury Inn & Suites Poplar Bluff 10/10 Excellent "The staff was very friendly. " [](https://expedia.co.uk/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) ![Charming 2 bedroom cabin on a beautiful private lake.](//images.trvl-media.com/lodging/120000000/119320000/119310900/119310813/c347e331_y.jpg) ### Charming 2 bedroom cabin on a beautiful private lake. 10/10 Excellent "Hot tub fantastic. Very clean and organized." [](https://expedia.co.uk/Arcadia-Hotels-Charming-2-Bedroom-Cabin-On-A-Beautiful-Private-Lake.h119310813.Hotel-Information) ![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg) ### Motel 6 Poplar Bluff, MO 10/10 Excellent "Everything was great. I was traveling with 2 dogs. Everyone was great. I would only question the choice of the bathroom sink. Very unhandy. Otherwise a great value. " [](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Hampton Inn Poplar Bluff](//images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg) ### Hampton Inn Poplar Bluff 10/10 Excellent "Nice place. Friendly staff." [](https://expedia.co.uk/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ![Sam A Baker State Park](//images.trvl-media.com/lodging/115000000/114280000/114277700/114277672/c09183cb_y.jpg) ### Sam A Baker State Park 8/10 Good "Rustic " [](https://expedia.co.uk/Patterson-Hotels-Sam-A-Baker-State-Park.h114277672.Hotel-Information) ![Camp Stonebass-Lake House-Hottub](//images.trvl-media.com/lodging/116000000/115660000/115656000/115655964/3255fa08_y.jpg) ### Camp Stonebass-Lake House-Hottub 10/10 Excellent "We really enjoyed our time at the house." [](https://expedia.co.uk/Wappapello-Hotels-Camp-Stonebass-Lake-House-Hottub.h115655964.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Wayne County - [Piedmont Hotels](https://expedia.co.uk/Piedmont-Hotels.d3000445413.Travel-Guide-Hotels) - [Wappapello Hotels](https://expedia.co.uk/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Patterson Hotels](https://expedia.co.uk/Patterson-Hotels.d553248635975853657.Travel-Guide-Hotels) - [Greenville Hotels](https://expedia.co.uk/Greenville-Hotels.d553248634983564794.Travel-Guide-Hotels) - [Mill Spring Hotels](https://expedia.co.uk/Mill-Spring-Hotels.d553248634983294338.Travel-Guide-Hotels) - [Lowndes Hotels](https://expedia.co.uk/Lowndes-Hotels.d845959773057740800.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Johnson's Shut-ins State Park](https://expedia.co.uk/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Sam A Baker State Park](https://expedia.co.uk/Patterson-Hotels-Sam-A-Baker-State-Park.h114277672.Hotel-Information) - [Camp Stonebass-Lake House-Hottub](https://expedia.co.uk/Wappapello-Hotels-Camp-Stonebass-Lake-House-Hottub.h115655964.Hotel-Information) - [Motel 6 Poplar Bluff, MO](https://expedia.co.uk/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) - [Hampton Inn Poplar Bluff](https://expedia.co.uk/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) - [Drury Inn & Suites Poplar Bluff](https://expedia.co.uk/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) [See a list of all hotels in Wayne County](https://expedia.co.uk/All-Wayne-County-Hotels.d553248635976433836.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Wayne County on Expedia.com](https://www.expedia.com/Destinations-In-Wayne-County.d553248635976433836.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Hotels in Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Hotel-Destinations) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)