Title: Holiday Rentals St. Charles County from £104: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [St. Charles County Hotels](https://expedia.co.uk/Destinations-In-St-Charles-County.d553248635083913790.Hotel-Destinations)[St. Charles County Car Hire](https://expedia.co.uk/Destinations-In-St-Charles-County.d553248635083913790.Car-Hire-Destinations)[St. Charles County Holidays](https://expedia.co.uk/St-Charles-County.d553248635083913790.Holidays-City-Breaks) ![Scenic view of bluffs covered with colorful Autumn foliage at Klondike County Park in St. Charles County, Missouri](https://images.trvl-media.com/place/553248635083913790/8ca9905e-75ac-4c73-af13-25159571cfe8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Holiday Rentals in St. Charles County - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Our top choices for St. Charles County holiday rentals ![TV](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/f3578af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/6ed864ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/b7b6310c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/1e8558f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic Augusta Cabin by StayLage [](https://www.expedia.co.uk/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information) Augusta 9.2/10 Wonderful (5) "I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) teresa s. £204 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/46f64c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/c7db1510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/0589f65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/5d45ed4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Adorable Augusta Cabin [](https://www.expedia.co.uk/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information) Augusta 9.0/10 Wonderful (9) "Absolutely beautiful area. Cabin is so cozy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron £167 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/112000000/111720000/111715700/111715679/e7f27cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111720000/111715700/111715679/1cb8c44d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/112000000/111720000/111715700/111715679/3fa24bb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s area](https://images.trvl-media.com/lodging/112000000/111720000/111715700/111715679/e8e12f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quaint and Cozy Hamlet [](https://www.expedia.co.uk/St-Louis-Hotels-Quaint-And-Cozy-Hamlet.h111715679.Hotel-Information) O'Fallon 9.4/10 Exceptional (13) "Overall great time- communication was wonderful with Kevin, neighborhood was quiet, perfect for our stay. The house wasn’t as clean as I’d expect but besides that, great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Madison A. £264 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Quaint-And-Cozy-Hamlet.h111715679.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/w2033h1365x15y0-e5f03757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/aa3a0aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/adda266d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/5b9ff4d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marigold Cottage by StayLage [](https://www.expedia.co.uk/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) Augusta 7.8/10 Good (7) "We loved the cottage and the town of Augusta. Would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler S. £278 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/117000000/116420000/116418600/116418519/78ade58c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/117000000/116420000/116418600/116418519/a21babb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116420000/116418600/116418519/23f23f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116420000/116418600/116418519/0d5c9899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St. Peters Private Basement Guesthouse: Farm Views - Visit Family & Friends [](https://www.expedia.co.uk/St-Louis-Hotels-St-Peters-Private-Basement-Guesthouse-Farm-Views-Sports-Moms-Sleeps-6.h116418519.Hotel-Information) St. Peters 9.8/10 Exceptional (7) "Very clean rental and in a very secure neighborhood. Is also conveniently located near restaurants and stores." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine N. £212 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-St-Peters-Private-Basement-Guesthouse-Farm-Views-Sports-Moms-Sleeps-6.h116418519.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/757836ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/d72dc64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/ae41a081.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100820000/100818500/100818493/f1c77f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cozy Family Retreat [](https://www.expedia.co.uk/St-Louis-Hotels-The-Cozy-Family-Retreat.h100818493.Hotel-Information) O'Fallon 8.4/10 Very good (23) "It fit our needs perfectly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David B. £224 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-The-Cozy-Family-Retreat.h100818493.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/84000000/83300000/83295200/83295123/bc875d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83300000/83295200/83295123/907e24c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/84000000/83300000/83295200/83295123/6ba3a54c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/84000000/83300000/83295200/83295123/a6326d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pool & Gym. Your Next Trip! [](https://www.expedia.co.uk/St-Louis-Hotels-Pool-Gym-Your-Next-Trip.h83295123.Hotel-Information) O'Fallon 10/10 Exceptional (1) "It was a fine short stay. Good breakfast!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth B. £191 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Pool-Gym-Your-Next-Trip.h83295123.Hotel-Information) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/124000000/123160000/123157400/123157321/d320d79e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/124000000/123160000/123157400/123157321/d4cd81c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/124000000/123160000/123157400/123157321/4b0e5a75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/124000000/123160000/123157400/123157321/6cc9d686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 3 Bedroom/ Family Comfort & Convenient Location [](https://www.expedia.co.uk/St-Louis-Hotels-Cozy-3-Bedroom-Family-Comfort-Convenient-Location.h123157321.Hotel-Information) Wentzville 10/10 Exceptional (1) "We had a wonderful stay! The home was very clean, check-in was super easy, and it was the perfect place for our family. Everything was exactly as described and we felt comfortable the entire time. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tricia W. £235 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Cozy-3-Bedroom-Family-Comfort-Convenient-Location.h123157321.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/6592837a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/31fe0e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/a7ae62bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/ffe29d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St. Charles 1860's Gem - Sleeps 6! [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information) St. Charles Historic District 9.8/10 Exceptional (136) "This was such a cute historical home and was perfect for our weekend in St Charles!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isabelle C. £193 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/dfd36c33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/5742a366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/21635ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/267d66bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Saint Charles [](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information) Saint Charles 9.2/10 Wonderful (17) "We group of senior ladies thoroughly enjoyed our weekend at Casa de Saint Charles. The accommodations were perfect, inside and out. Our hosts were very accessible and made sure all our wants and needs were taken care of. What a wonderful home! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosalind W. £298 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/8b0cefb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/w1600h1064x0y68-502efe55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/55a58440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/084c4e0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Prime Loft of Main Street [](https://www.expedia.co.uk/St-Louis-Hotels-Prime-Loft-Of-Main-Street.h68768642.Hotel-Information) St. Charles Historic District 9.8/10 Exceptional (101) "The loft was very nice, very clean, well appointed, and in a perfect location. I highly recommend this property!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary ann S. £173 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Prime-Loft-Of-Main-Street.h68768642.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/54e27f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/dab47660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/656d8a9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/9764dd9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cul-de-Sac Retreat [](https://www.expedia.co.uk/St-Louis-Hotels-The-Cul-De-Sac-Retreat.h100819176.Hotel-Information) Saint Charles 8.4/10 Very good (9) "Great house, great location - close to the St. Charles convention center" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe H. £231 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-The-Cul-De-Sac-Retreat.h100819176.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544626/92ed888a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544626/6238f9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544626/5f468ceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544626/fa5cf4bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison House 2 -Walk to Main St [](https://www.expedia.co.uk/St-Louis-Hotels-Madison-House-2-Walk-To-Main-St.h111544626.Hotel-Information) St. Charles Historic District 7.2/10 Good (9) "This property was clean and offered basic amenities, but is a very old historic home and lacks the luster and comfort of most homes, but has needed repairs and improvements to have a 5 star rating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimbelry D. £189 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Madison-House-2-Walk-To-Main-St.h111544626.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/faf4ff3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/c1443a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/0e044ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/59492674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 6th street 101 - Walk to Main St [](https://www.expedia.co.uk/St-Louis-Hotels-6th-Street-101-Walk-To-Main-St.h116658446.Hotel-Information) St. Charles Historic District 10/10 Exceptional (1) £218 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-6th-Street-101-Walk-To-Main-St.h116658446.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/74105de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/3158546a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/0c1b338f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/3c074e66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Below Deck Suite [](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information) Saint Charles 9.0/10 Wonderful (2) "Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy B. £232 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111980000/111975400/111975314/6be8764a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/112000000/111980000/111975400/111975314/ed9ea4b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111980000/111975400/111975314/1055b1b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111980000/111975400/111975314/w1022h687x3y0-9e0d7ab1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Great Room - fully cozy & private Townhome [](https://www.expedia.co.uk/St-Louis-Hotels-The-Great-Room-Fully-Cozy-Private-Townhome.h111975314.Hotel-Information) Saint Charles 10/10 Exceptional (1) "The place was beautiful and decorated well. Our experience was great and i recommend this rental. Would be nice if they honored military discount as I am a veteran. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rodney M. £223 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-The-Great-Room-Fully-Cozy-Private-Townhome.h111975314.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/87db6a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/d774c21e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/4fee3a1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/8360c155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazing Renovated Historic Loft on Main Street [](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information) St. Charles Historic District 10/10 Exceptional (57) "Great place and location. Owners were easy to work with." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cory M. £181 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113620000/113613600/113613502/e0a12810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table football](https://images.trvl-media.com/lodging/114000000/113620000/113613600/113613502/c1dc182e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113620000/113613600/113613502/184aa210.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, table football](https://images.trvl-media.com/lodging/114000000/113620000/113613600/113613502/d857cce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3BR Historic St. Charles, MO-Walking distance to Main Street [](https://www.expedia.co.uk/St-Louis-Hotels-3BR-Historic-St-Charles.h113613502.Hotel-Information) St. Charles Historic District 9.8/10 Exceptional (16) "The location was perfect for a girls night out! Home was very well kept and comfy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rachel L. £390 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/St-Louis-Hotels-3BR-Historic-St-Charles.h113613502.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/84000000/83610000/83605400/83605308/7405cfec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83610000/83605400/83605308/f671dd2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83610000/83605400/83605308/8149b724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/84000000/83610000/83605400/83605308/c5928e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great for Business Travelers! Pool + Gym [](https://www.expedia.co.uk/St-Louis-Hotels-Great-For-Business-Travelers-Pool-Gym.h83605308.Hotel-Information) O'Fallon £135 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Great-For-Business-Travelers-Pool-Gym.h83605308.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100930000/100923700/100923601/e7e567fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100930000/100923700/100923601/c83eb158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100930000/100923700/100923601/5d7803c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100930000/100923700/100923601/7aca00a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious Wentzville Retreat by StayLage [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Wentzville-Retreat-By-StayLage.h100923601.Hotel-Information) Wentzville 9.8/10 Exceptional (6) "My family of 7 greatly enjoyed our stay at this home in Wentzville. The home was clean, centrally located, and spacious for our large family. I will definitely stay here again when we visit family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal E. £502 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Wentzville-Retreat-By-StayLage.h100923601.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-11&endDate=2026-01-12®ionId=553248635083913790&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=CONDO) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=CHALET) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=COTTAGE) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=CABIN) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles+County%2C+Missouri%2C+United+States+of+America®ionId=553248635083913790&latLong=38.783176%2C-90.482122&adults=2&startDate=2026-03-27&d1=2026-03-27&endDate=2026-03-30&d2=2026-03-30&lodging=VILLA) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-St-Charles-County.d553248635083913790.Holiday-Rental-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-St-Charles-County.d553248635083913790.Holiday-Rental-Destinations) ## Top St. Charles County Hotel Reviews ![Hampton Inn St. Louis-Downtown (At the Gateway Arch)](https://images.trvl-media.com/lodging/1000000/30000/22600/22520/w3837h2560x0y0-a6354f1b_y.jpg) ### Hampton Inn St. Louis-Downtown (At the Gateway Arch) 10/10 Excellent "Nice friendly staff. Clean, well stocked room. Fresh breakfast, nice variety of food. " [](https://expedia.co.uk/St-Louis-Hotels-Hampton-Inn-Gateway-Arch-Downtown.h22520.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg) ### The Wildwood Hotel 10/10 Excellent "Room clean; staff very nice. Breakfast- alright for on the go, but have had much better." [](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Best Western St. Louis-Kirkwood Route 66](https://images.trvl-media.com/lodging/1000000/10000/500/415/b788e069_y.jpg) ### Best Western St. Louis-Kirkwood Route 66 10/10 Excellent "Our stay was quiet and comfortable. Only a well used slightly stained bathtub kept this review from being excellent. " [](https://expedia.co.uk/St-Louis-Hotels-Best-Western-Kirkwood-Inn.h415.Hotel-Information) ![Renaissance St. Louis Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1_y.jpg) ### Renaissance St. Louis Airport Hotel 10/10 Excellent "Clean rooms and friendly, accommodating staff. " [](https://expedia.co.uk/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg) ### Pear Tree Inn St. Louis Airport 10/10 Excellent "Room was spotless. The lobby area was comfortable, and the staff was warm and eager to engage." [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg) ### Home2 Suites by Hilton St. Louis Downtown 10/10 Excellent "The room was spotless and had adequate space. The accomodations were high quality and the staff was courteous and friendly. Yummy apples! " [](https://expedia.co.uk/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "Hotel is very nice and quiet. Staff was polite and helpful. Great visit!" [](https://expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "The room was impeccable and the staff were super friendly. I plan to say in the future." [](https://expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton 10/10 Excellent "Great property. " [](https://expedia.co.uk/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ## Find out more about St. Charles County **Everything you need to know about** **St. Charles County** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles County holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles County holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. **St. Charles County holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in St. Charles County. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A St. Charles County holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of St. Charles County holiday rentals we have selected for you start as low as £104 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on St. Charles County rentals** At Expedia, we put the best St. Charles County holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top St. Charles County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles County holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Popular St. Charles County Cities - [O'Fallon Holiday Rentals ](https://expedia.co.uk/OFallon-Holiday-Rentals.d140195.Travel-Guide-HolidayRentals) - [Augusta Holiday Rentals ](https://expedia.co.uk/Augusta-Holiday-Rentals.d6250878.Travel-Guide-HolidayRentals)