Title: Holiday Rentals St. Charles from £114: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk

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![Urban Tree Canopy in historic Saint Charles Missouri](https://images.trvl-media.com/place/9786/33221430-84a2-48e0-81c1-7426ab806e5b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/9786/33221430-84a2-48e0-81c1-7426ab806e5b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[1 May - 3 May](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[29 May - 31 May](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for St. Charles holiday rentals

![Smart TV](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/779822a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/55a58440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/2039c7b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/69000000/68770000/68768700/68768642/f288c4f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Prime Loft of Main Street

[](https://www.expedia.co.uk/St-Louis-Hotels-Prime-Loft-Of-Main-Street.h68768642.Hotel-Information)

St. Charles Historic District

9.8/10

Exceptional

(104 reviews)

"The loft was very nice, very clean, well appointed, and in a perfect location. I highly recommend this property!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary ann S.

£178

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Prime-Loft-Of-Main-Street.h68768642.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/104000000/103990000/103987700/103987661/297b8e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, offices](https://images.trvl-media.com/lodging/104000000/103990000/103987700/103987661/d1c26363.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103990000/103987700/103987661/a0e79fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103990000/103987700/103987661/99325b43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Historic 4‑BR Farmhouse • Steps to Main Street

[](https://www.expedia.co.uk/St-Louis-Hotels-Chic-Farmhouse-At-Historic-Frenchtown-4BR-House.h103987661.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(22 reviews)

"The house was perfect for our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan F.

£444

includes taxes & fees

10 Mar - 11 Mar

[](https://www.expedia.co.uk/St-Louis-Hotels-Chic-Farmhouse-At-Historic-Frenchtown-4BR-House.h103987661.Hotel-Information)

![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/f0fef17d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/5bc39b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/a03d491d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/3158546a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Below Deck Suite

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information)

Saint Charles

9.0/10

Wonderful

(2 reviews)

"Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy B.

£164

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/88000000/87360000/87354000/87353997/928eaf94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/88000000/87360000/87354000/87353997/bb7198fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/88000000/87360000/87354000/87353997/87475e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/88000000/87360000/87354000/87353997/478dc170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Main Street Living! 2 Bedroom Unit right On Main!

[](https://www.expedia.co.uk/St-Louis-Hotels-Main-Street-Living-2-Bedroom-Unit-Right-On-Main.h87353997.Hotel-Information)

St. Charles Historic District

9.6/10

Exceptional

(35 reviews)

"Great Stay and great location! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Angela

£258

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Main-Street-Living-2-Bedroom-Unit-Right-On-Main.h87353997.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/c8faea22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/6d66241c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/3580d825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/0abbf90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lofts of North Main Street

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Lofts-Of-North-Main-Street.h66454439.Hotel-Information)

St. Charles Historic District

9.6/10

Exceptional

(160 reviews)

"Very nice place near all the action. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Weston G.

£168

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Lofts-Of-North-Main-Street.h66454439.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/0e044ece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/c1443a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/faf4ff3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116660000/116658500/116658446/59492674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 6th street 101 - Walk to Main St

[](https://www.expedia.co.uk/St-Louis-Hotels-6th-Street-101-Walk-To-Main-St.h116658446.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(1 review)

£198

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-6th-Street-101-Walk-To-Main-St.h116658446.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/46289692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/25e66eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/f09d0cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/aa66c9c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Cottage on Main st- Near Downtown

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Unit-On-Main-St-Near-Downtown.h114776148.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(7 reviews)

"The house was perfect. Clean, organized and portrayed exactly as in the pictures. We loved our stay here. The host was punctual and attentive to all questions. We would definitely stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa P.

£160

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Unit-On-Main-St-Near-Downtown.h114776148.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/3b4ea729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/dcaa9c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/43dcbab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/63b04d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Unit on Historic Main Street 

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Duplex-On-Main-Street-Near-Historic-Main-Street.h114811361.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(11 reviews)

"Wonderful host and accomodations !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew K.

£167

includes taxes & fees

10 Feb - 11 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Duplex-On-Main-Street-Near-Historic-Main-Street.h114811361.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/016cf9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/f2f70f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/21635ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/5742a366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de Saint Charles

[](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information)

Saint Charles

9.2/10

Wonderful

(17 reviews)

"We group of senior ladies thoroughly enjoyed our weekend at Casa de Saint Charles. The accommodations were perfect, inside and out. Our hosts were very accessible and made sure all our wants and needs were taken care of. What a wonderful home! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rosalind W.

£223

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information)

![TV, books](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/8ece9774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/9b1e50b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, books](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/8857eb8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/808ab6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### St. Charles 1860's Gem - Sleeps 6!

[](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information)

St. Charles Historic District

9.8/10

Exceptional

(137 reviews)

"Very comfortable house, beds are very comfy as well which is rare in a lot of VRBOs. Would definitely recommend! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Phillip R.

£170

includes taxes & fees

10 Feb - 11 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/dc1bb429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/48d1cc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/0f42d269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, WiFi](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/33267681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

[](https://www.expedia.co.uk/St-Louis-Hotels-5th-Street-1-Historic-5th-Street-House-Fully-Rehabbed-1.h92203228.Hotel-Information)

St. Charles Historic District

9.4/10

Exceptional

(13 reviews)

"House was beautiful. Very nice quiet stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy S.

£178

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-5th-Street-1-Historic-5th-Street-House-Fully-Rehabbed-1.h92203228.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/3f60ffb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/80de4605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/36b99900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/87db6a60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Amazing Renovated Historic Loft on Main Street

[](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(58 reviews)

"Great place and location. Owners were easy to work with."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cory M.

£184

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/9764dd9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/e85f6ae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/656d8a9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100819200/100819176/54e27f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cul-de-Sac Retreat

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Cul-De-Sac-Retreat.h100819176.Hotel-Information)

Saint Charles

8.4/10

Very good

(9 reviews)

"Great house, great location - close to the St. Charles convention center"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joe H.

£188

includes taxes & fees

10 Feb - 11 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Cul-De-Sac-Retreat.h100819176.Hotel-Information)

![Games room](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544628/647d7eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544628/c62a38a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544628/cd0bd330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer](https://images.trvl-media.com/lodging/112000000/111550000/111544700/111544628/23991724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Madison House 1 -Walk to Main St

[](https://www.expedia.co.uk/St-Louis-Hotels-Madison-House-1-Walk-To-Main-St.h111544628.Hotel-Information)

St. Charles Historic District

8.6/10

Excellent

(17 reviews)

"The house was clean and well stocked, location was great, and plenty of street parking. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad K.

£178

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Madison-House-1-Walk-To-Main-St.h111544628.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/98000000/97230000/97225700/97225622/d9b4bb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/98000000/97230000/97225700/97225622/50375db8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, WiFi](https://images.trvl-media.com/lodging/98000000/97230000/97225700/97225622/19b2a3a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/98000000/97230000/97225700/97225622/ef648042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 1st Capitol Mansion - Suite 401

[](https://www.expedia.co.uk/St-Louis-Hotels-1st-Capitol-Mansion-Suite-401.h97225622.Hotel-Information)

St. Charles Historic District

7.6/10

Good

(8 reviews)

"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emily L.

£178

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-1st-Capitol-Mansion-Suite-401.h97225622.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879600/95879524/c37516f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95880000/95879600/95879524/efc70ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95880000/95879600/95879524/38a287fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95880000/95879600/95879524/308cfe0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Historic Bricks on Main

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Historic-Bricks-On-Main.h95879524.Hotel-Information)

St. Charles Historic District

8.8/10

Excellent

(15 reviews)

"Host was very welcoming and helpful when we have any questions no matter what time of day. The place was very quaint and comfy. We would highly recommend. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chelsea L.

£155

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Historic-Bricks-On-Main.h95879524.Hotel-Information)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99680000/99672100/99672035/899f1dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99680000/99672100/99672035/ee4b16a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99680000/99672100/99672035/670f9e50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99680000/99672100/99672035/02afa9a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Duplex Hideaway in St. Charles, MO

[](https://www.expedia.co.uk/St-Louis-Hotels-Duplex-Hideaway-In-St-Charles.h99672035.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(5 reviews)

"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen M.

£169

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Duplex-Hideaway-In-St-Charles.h99672035.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/68999da7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/0a37a482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/w3900h2591x0y4-c1cce84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/893add03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 2 bed Townhome by StayLage

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bed-Townhome-By-StayLage.h88659965.Hotel-Information)

Saint Charles

9.0/10

Wonderful

(9 reviews)

"Great location, clean, and management was informative and reacted to any needs quickly. Would recommend to anyone."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan D.

£210

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bed-Townhome-By-StayLage.h88659965.Hotel-Information)

![Fridge, microwave, stovetop, toaster](https://images.trvl-media.com/lodging/100000000/99520000/99519000/99518901/c7c5c786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/100000000/99520000/99519000/99518901/7f98cd91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, toaster](https://images.trvl-media.com/lodging/100000000/99520000/99519000/99518901/2a429583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99520000/99519000/99518901/462d3e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Duplex on Main

[](https://www.expedia.co.uk/St-Louis-Hotels-Charming-Duplex-On-Main.h99518901.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(16 reviews)

"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wendy K.

£177

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Charming-Duplex-On-Main.h99518901.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/a8ea8aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/a47fa635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/e82c5584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/3bc19e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Original Custom House!

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Original-Custom-House.h83393465.Hotel-Information)

St. Charles Historic District

9.8/10

Exceptional

(36 reviews)

"The location is excellent. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

McRay H.

£258

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-The-Original-Custom-House.h83393465.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23&regionId=9786&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find holiday rentals that suit your style

Aparthotels

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=APARTMENT)

Private holiday homes

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VACATION_HOME)

Condos

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CONDO)

Cabins

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CABIN)

Cottages

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=COTTAGE)

Villas

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VILLA)

Chalets

[](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America&regionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CHALET)

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## Top St. Charles Hotel Reviews

![Pear Tree Inn St. Louis Airport](https://images.trvl-media.com/lodging/2000000/1100000/1096600/1096579/fc156cf2_y.jpg)

### Pear Tree Inn St. Louis Airport

10/10 Excellent

"Staff was incredibly kind and helpful. They sent a shuttle to pick me up at the car rental place! The room was clean, the beds were comfortable, and the breakfast buffet had great options, even for our gluten-free family member. "

[](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Airport.h1096579.Hotel-Information)

![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/78b2a688_y.jpg)

### Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Yes… never was in a hotel where complimentary dinner included."

[](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information)

![Marriott St. Louis Grand](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/4c313173_y.jpg)

### Marriott St. Louis Grand

10/10 Excellent

"Room was very nice. Beds super comfy. Hotel lobby provided a great space to gather with friends."

[](https://expedia.co.uk/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information)

![Live by Loews - St.Louis](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f_y.jpg)

### Live by Loews - St.Louis

10/10 Excellent

"Very clean and helpful staff!"

[](https://expedia.co.uk/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information)

![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/335a172e_y.jpg)

### Hyatt Regency St. Louis at The Arch

10/10 Excellent

"View of Gateway Arch, early check-in, friendly staff, walkable"

[](https://expedia.co.uk/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information)

![Magnolia Hotel St. Louis, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3_y.jpg)

### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Nice clean rooms and friendly staff. Oh, the cookies were delicious 😋. "

[](https://expedia.co.uk/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information)

![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b_y.jpg)

### Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"Location "

[](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information)

![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg)

### Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent

"From check in my time at Country Inn was wonderful! The people are so very kind and helpful, the building is spotless, location is perfect and I had everything I needed. I recommend the Country Inn & Suites!"

[](https://expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/cd6b7758_y.jpg)

### 21C Museum Hotel St Louis 

10/10 Excellent

"Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature and next time I'm in STL I will be back!"

[](https://expedia.co.uk/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information)

## Find out more about St. Charles

**Everything you need to know about** **St. Charles** **holiday rentals**

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**St. Charles holiday rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A St. Charles holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of St. Charles holiday rentals we have selected for you start as low as £114 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on St. Charles rentals**

At Expedia, we put the best St. Charles holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

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- [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations)
- [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations)

## Frequently asked questions

### Can I find holiday rentals in St. Charles?

### What are some of the best holiday rentals that St. Charles has to offer?

### How many holiday rentals are there in St. Charles?

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### What are holiday rentals like in St. Charles?

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