Title: Holiday Rentals St. Charles from £100: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in St. Charles](https://expedia.co.uk/St-Charles-Hotels.d9786.Travel-Guide-Hotels)[Flights to St. Charles](https://expedia.co.uk/Cheap-Flights-To-St-Charles.d9786.Travel-Guide-Flights)[Things to do in St. Charles](https://expedia.co.uk/Things-To-Do-In-St-Charles.d9786.Travel-Guide-Activities)[St. Charles Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-St-Charles.d9786.Car-Hire-Guide)[St. Charles Holidays](https://expedia.co.uk/St-Charles.d9786.Holidays-City-Breaks) ![The historic 18th century Main Street through the brick paved old town of St. Charles, Missouri, along the Missouri River.](https://images.trvl-media.com/place/9786/f9ac7810-8943-4220-bb04-c0a58b2e9dc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/9786/f9ac7810-8943-4220-bb04-c0a58b2e9dc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [24 Apr - 26 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [5 Jun - 7 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [3 Jul - 5 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [31 Jul - 2 Aug](https://www.expedia.co.uk/Hotel-Search?regionId=9786&startDate=2026-07-31&endDate=2026-08-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Charles holiday rentals ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/ff8410c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/f7a9c2d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/6f923e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/751c7c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming open 4bd and screen-in porch! Sleeps 10! [](https://www.expedia.co.uk/St-Louis-Hotels-Charming-Open-4bd-And-Screen-In-Porch-Sleeps-10.h88972328.Hotel-Information) Saint Charles 9.2/10 Wonderful (36 reviews) "Stay here for 3 weeks. Place was just as described. Would recommend. Thank you " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eddy £410 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Charming-Open-4bd-And-Screen-In-Porch-Sleeps-10.h88972328.Hotel-Information) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/f0fef17d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/74105de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/5bc39b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100820000/100819700/100819682/a03d491d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Below Deck Suite [](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information) Saint Charles 9.0/10 Wonderful (2 reviews) "Overall good place for a family. The neighborhood is quiet and there is a good amount of space. Easy to find and to get places. You will hear the people upstairs and one bed was very squeaky. It was very clean and the couches are very comfy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy B. £277 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-The-Below-Deck-Suite.h100819682.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035036/485d26cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035036/7b35da19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035036/17447f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035036/6c9b403d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spring SALE,Cozy 2BR Chalet, Hot Tub 1.2 Acres! [](https://www.expedia.co.uk/St-Louis-Hotels-February-SALE-NOW-St-Charles-Chalet-Hot-Tub.h113035036.Hotel-Information) Saint Charles 8.8/10 Excellent (3 reviews) "We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie R. £422 includes taxes & fees 18 Apr - 19 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-February-SALE-NOW-St-Charles-Chalet-Hot-Tub.h113035036.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/121000000/121000000/120997100/120997076/ba0bc24f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/121000000/120997100/120997076/02cf9664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/121000000/120997100/120997076/19e2ee90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/121000000/120997100/120997076/4e64aece.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### March Madness SALE NOW, Luxe stay, Private, HUGE Game Rm, Hot Tub, .67 acres [](https://www.expedia.co.uk/St-Louis-Hotels-FALL-SALE-NOW-Private-Game-Rm-Hot-Tub.h120997076.Hotel-Information) Saint Charles 10/10 Exceptional (1 review) "Such a perfect place to stay for a weekend with a larger group! Close to a lot of different things and had pretty much everything you could need. It was also super clean and nice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda P. £721 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-FALL-SALE-NOW-Private-Game-Rm-Hot-Tub.h120997076.Hotel-Information) ![Smart TV, stereo](https://images.trvl-media.com/lodging/45000000/44580000/44571600/44571505/79ab5fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/45000000/44580000/44571600/44571505/c7ac99e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, stereo](https://images.trvl-media.com/lodging/45000000/44580000/44571600/44571505/ad375d97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/45000000/44580000/44571600/44571505/1a12a5b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location! [](https://www.expedia.co.uk/St-Louis-Hotels-Aunt-Doodles-House-8-Blocks-From-Historic-Main-Street-Convenient-Location.h44571505.Hotel-Information) St. Charles Historic District 9.6/10 Exceptional (75 reviews) "Great communication from host, cute house in an awesome location. Will definitely be staying again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sydney W. £170 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Aunt-Doodles-House-8-Blocks-From-Historic-Main-Street-Convenient-Location.h44571505.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/016cf9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/45965e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/21635ab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/f2f70f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Saint Charles [](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information) Saint Charles 9.4/10 Exceptional (18 reviews) "The home was perfect for our multi-family gathering. There was lots of room for everyone and the location was great for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla Z. £287 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/c8faea22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/3580d825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/1d241474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66460000/66454500/66454439/0abbf90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lofts of North Main Street [](https://www.expedia.co.uk/St-Louis-Hotels-The-Lofts-Of-North-Main-Street.h66454439.Hotel-Information) St. Charles Historic District 9.6/10 Exceptional (168 reviews) "Host was very responsive and location was perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peggy K. £199 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-The-Lofts-Of-North-Main-Street.h66454439.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/79000000/78440000/78437900/78437822/be8982a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/79000000/78440000/78437900/78437822/f7561ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78440000/78437900/78437822/9caba79e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/79000000/78440000/78437900/78437822/b1b684f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard! [](https://www.expedia.co.uk/St-Louis-Hotels-New-Remodel-In-St-Charles-Sleeps-10-New-Patio-Large-Fenced-In-Backyard.h78437822.Hotel-Information) St. Charles Historic District 9.6/10 Exceptional (69 reviews) "Very clean and comfortable. Enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana S. £365 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-New-Remodel-In-St-Charles-Sleeps-10-New-Patio-Large-Fenced-In-Backyard.h78437822.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035043/f563a69b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035043/03aadc72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035043/87ac399f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113040000/113035100/113035043/205eab45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Discover, Spring SALE, Game RM, Hot Tub .5 Acres, 1blk to Family Arena [](https://www.expedia.co.uk/St-Louis-Hotels-STOP-LOOK-February-SALE-NOW-Game-RM-Hot-Tub.h113035043.Hotel-Information) Saint Charles 10/10 Exceptional (5 reviews) "Wonderful place to stay for a group trip! Lots of space and activities for everyone to do. The hosts are very accommodating and quick to respond for any last minute questions. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott S. £562 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-STOP-LOOK-February-SALE-NOW-Game-RM-Hot-Tub.h113035043.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/82000000/81510000/81509800/81509771/d1074747.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/82000000/81510000/81509800/81509771/11a3d218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/82000000/81510000/81509800/81509771/1db5a3ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/82000000/81510000/81509800/81509771/aa3bff55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2 Bdr Upstairs Apt Walking Distance to Main St [](https://www.expedia.co.uk/St-Louis-Hotels-Luxurious-2-Bedroom-Abode-With-Elevated-Comforts-Near-Main-Street.h81509771.Hotel-Information) Saint Charles 9.4/10 Exceptional (3 reviews) "The best price-value ratio. Quiet neighborhood, close to the city center." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamas P. £220 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Luxurious-2-Bedroom-Abode-With-Elevated-Comforts-Near-Main-Street.h81509771.Hotel-Information) ![TV, books](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/8ece9774.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/808ab6d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/9b1e50b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34490000/34480500/34480442/a7ae62bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St. Charles 1860's Gem - Sleeps 6! [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information) St. Charles Historic District 9.8/10 Exceptional (148 reviews) "Another great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kate G. £198 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-1860s-Gem-Sleeps-8.h34480442.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393467/c3151f09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393467/e19f192f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393467/9f6898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393467/1a5467b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Main Street Balcony Apartment [](https://www.expedia.co.uk/St-Louis-Hotels-Main-Street-Balcony-Apartment-By-StayLage.h83393467.Hotel-Information) St. Charles Historic District 9.6/10 Exceptional (36 reviews) "Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke I. £324 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Main-Street-Balcony-Apartment-By-StayLage.h83393467.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203236/bf8641cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203236/b9c72f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203236/ccf60a74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203236/e19488ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Music House · Music House on Main Street at The Wine Garden [](https://www.expedia.co.uk/St-Louis-Hotels-Music-House-Music-House-On-Main-Street-At-The-Wine-Garden.h92203236.Hotel-Information) Saint Charles 9.2/10 Wonderful (15 reviews) "Great place.Thanks" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex T. £673 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Music-House-Music-House-On-Main-Street-At-The-Wine-Garden.h92203236.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/128000000/127700000/127695200/127695155/421cae9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/128000000/127700000/127695200/127695155/48e31c01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/128000000/127700000/127695200/127695155/627a372b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/128000000/127700000/127695200/127695155/9687d5ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bourbon & Brass | Speakeasy-Inspired 2BDR [](https://www.expedia.co.uk/St-Louis-Hotels-The-Bourbon-Brass-Speakeasy-Inspired-2BDR.h127695155.Hotel-Information) St. Charles Historic District £235 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-The-Bourbon-Brass-Speakeasy-Inspired-2BDR.h127695155.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/80000000/79060000/79052500/79052474/4d940b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79060000/79052500/79052474/8238b71c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/80000000/79060000/79052500/79052474/b85e6135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/80000000/79060000/79052500/79052474/ee3dee8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home Near Main Street-Covered Patio-Hot Tub! [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-Newly-Remodeled-Home-Sleeps-12.h79052474.Hotel-Information) Saint Charles 9.6/10 Exceptional (31 reviews) "Great house and great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike L. [](https://www.expedia.co.uk/St-Louis-Hotels-St-Charles-Newly-Remodeled-Home-Sleeps-12.h79052474.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/3f60ffb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/f97626f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/36b99900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/67000000/66410000/66400800/66400703/80de4605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amazing Renovated Historic Loft on Main Street [](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information) St. Charles Historic District 10/10 Exceptional (59 reviews) "Lovely accommodations, very clean, well equipped, great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily B. £208 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Amazing-Renovated-Historic-Loft-On-Main-Street.h66400703.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/68999da7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/893add03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/c286090f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88660000/88660000/88659965/w3900h2591x0y4-c1cce84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to St. Charles Entertainment [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bed-Townhome-By-StayLage.h88659965.Hotel-Information) Saint Charles 9.0/10 Wonderful (10 reviews) "We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chloe £221 includes taxes & fees 15 Apr - 16 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bed-Townhome-By-StayLage.h88659965.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/115000000/114140000/114138900/114138882/a5f9eb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Paper towels](https://images.trvl-media.com/lodging/115000000/114140000/114138900/114138882/0fa9edc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114140000/114138900/114138882/5a3d242b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114140000/114138900/114138882/a8dd4cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Saint Charles White House [](https://www.expedia.co.uk/St-Louis-Hotels-Saint-Charles-White-House.h114138882.Hotel-Information) Saint Charles 8.6/10 Excellent (4 reviews) "It was great Needed towels but otherwise great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer R. £298 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Saint-Charles-White-House.h114138882.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/a8ea8aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/a47fa635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/e82c5584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83400000/83393500/83393465/fbe5fbf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Original Custom House! [](https://www.expedia.co.uk/St-Louis-Hotels-The-Original-Custom-House.h83393465.Hotel-Information) St. Charles Historic District 9.8/10 Exceptional (36 reviews) "The location is excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) McRay H. £265 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-The-Original-Custom-House.h83393465.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90020000/90014900/90014834/cea3d97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90020000/90014900/90014834/52e1571b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/91000000/90020000/90014900/90014834/ef940c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90020000/90014900/90014834/57959b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 2 Bedroom Townhome [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bedroom-Townhome-By-StayLage.h90014834.Hotel-Information) Saint Charles 8.0/10 Very good (13 reviews) "The stay here was amazing!! Live the little townhouse so much. Host was amazing!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina W. £217 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-2-Bedroom-Townhome-By-StayLage.h90014834.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22®ionId=9786&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=CABIN) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=CONDO) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=COTTAGE) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=CHALET) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=St.+Charles%2C+Missouri%2C+United+States+of+America®ionId=9786&latLong=38.788105%2C-90.497436&adults=2&startDate=2026-07-06&d1=2026-07-06&endDate=2026-07-09&d2=2026-07-09&lodging=VILLA) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Charles-Holiday-Rentals.d9786.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Charles-Holiday-Rentals.d9786.Travel-Guide-HolidayRentals) ## Top St. Charles Hotel Reviews ![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207_y.jpg) ### Hollywood Casino & Hotel St. Louis 8/10 Good "Easy to find" [](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 8/10 Good "Yes " [](https://expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "Excellent " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Drury Inn & Suites St. Louis Union Station](https://images.trvl-media.com/lodging/1000000/40000/37700/37651/151222b4_y.jpg) ### Drury Inn & Suites St. Louis Union Station 10/10 Excellent "Nice continental breakfast. Has a lot of variety for families. Complimentary drink tickets for the adults were a plus. We saved a lot of money with all that being included. " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-St-Louis-At-Union-Station.h37651.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db_y.jpg) ### Ameristar Casino Resort and Spa 8/10 Good "The room was great and clean. This was supposed to have a pool and spa but it wasn’t open or available " [](https://expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Embassy Suites by Hilton St. Louis St. Charles](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/ac68aac2_y.jpg) ### Embassy Suites by Hilton St. Louis St. Charles 10/10 Excellent "Will stay here again when in the St. Louis area, nice staff and hotel. Enjoyed my stay." [](https://expedia.co.uk/St-Louis-Hotels-Embassy-Suites-St-Louis-St-Charles.h1131105.Hotel-Information) ![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/79d56802_y.jpg) ### Drury Plaza Hotel St. Louis St. Charles 8/10 Good "The bed was comfortable and the room was clean. The breakfast however was not great, I guess pretty standard hotel food, but not very tasty." [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) ![Hilton St. Louis Airport](https://images.trvl-media.com/lodging/1000000/10000/7800/7743/c57dfbd2_y.jpg) ### Hilton St. Louis Airport 10/10 Excellent "Love this hotel! Very convenient and modern!" [](https://expedia.co.uk/St-Louis-Hotels-Hilton-St-Louis-Airport.h7743.Hotel-Information) ![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2_y.jpg) ### Country Inn & Suites by Radisson, St. Charles Historic District 10/10 Excellent "Great hotel. I was very happy with my stay. The room was spacious, clean and comfortable. Great location. Parking free and easy. I was pleased with the breakfast. Good variety and decent quality. " [](https://expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ## Find out more about St. Charles **Everything you need to know about** **St. Charles** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **St. Charles holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A St. Charles holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of St. Charles holiday rentals we have selected for you start as low as £100 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on St. Charles rentals** At Expedia, we put the best St. Charles holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) ## Frequently asked questions ### Can I find holiday rentals in St. Charles? ### What are some of the best holiday rentals that St. Charles has to offer? ### How many holiday rentals are there in St. Charles? ### What can I see and do in St. Charles? ### What are holiday rentals like in St. Charles? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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