Find the best Mississippi County Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Mississippi County Accommodation: Most Popular Cities to Stay
Charleston
East Prairie
Check prices for these dates
Our top choices for Mississippi County hotels
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.6 out of 10, (641 reviews)
"Clean rooms,"
Karl
The price is £49
includes taxes & fees
12 Jul - 13 Jul
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (414 reviews)
"It was not at all what I expected. The website showed a very good hotel. It was awful. I would not paid even $40/ night if I knew how awful it is. I felt bad for the ladies working on front desk."
Soheila
The price is £62
includes taxes & fees
15 Jun - 16 Jun
Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (106 reviews)
"Great"
Jackson
The price is £59
includes taxes & fees
15 Jun - 16 Jun
Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.4 out of 10, (287 reviews)
"Television in my room did not get any signal for being able to view any channels. Shower was horrible. Towel rack was broken with a handwritten sign to “Do Not Use”. Lobby was dead bolted in the morning so I couldn’t get any complimentary breakfast or coffee that was supposed to be included in the room rate. Will avoid this place in the future."
Matthew
The price is £60
includes taxes & fees
10 Jul - 11 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Mississippi County Hotel Reviews
Sleep Inn at Discovery Park of America
10/10 Excellent
Explore a world of travel with Expedia
Top cities in Mississippi County
Hotels near popular Attractions
Explore more hotels
- Super 8 by Wyndham Charleston/Sikeston East MO
- The Riverstone Hotel Charleston-Sikeston
- Drury Inn & Suites Sikeston, MO
- Days Inn and Suites by Wyndham Sikeston
- Hampton Inn Sikeston
- Peaceful secluded cabin located near Horseshoe Lake
- Best Western Plus Sikeston I-55
- Super 8 by Wyndham Sikeston/Miner Area
- Sleep Inn at Discovery Park of America
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
More ways to book
Expedia's Latest Trends
Hotels
- Hotels near Hollywood Casino Amphitheatre
- Hotels in Orange County
- All-Inclusive Hotels in San Diego County
- Hotels in Lakeview
- Hotels in San Francisco County
- Downtown St. Louis Hotels
- Hotels in Manchester
- Hotels in San Diego County
- All-Inclusive Hotels in Los Angeles County
- Hotels in Shrewsbury
- Hotels in Door County
- Hotels in Innsbrook
Cars
Packages
