Title: Hotels in East Prairie, MO - Best East Prairie Hotels from £43 - Fully Refundable Options - Expedia.co.uk

[Holiday Rentals in East Prairie](https://expedia.co.uk/East-Prairie-Holiday-Rentals.d3000349349.Travel-Guide-HolidayRentals)[East Prairie Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-East-Prairie.d3000349349.Car-Hire-Guide)[East Prairie Holidays](https://expedia.co.uk/East-Prairie.d3000349349.Holidays-City-Breaks)

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## Go beyond your typical stay in East Prairie

Pool

[](https://www.expedia.co.uk/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-01-26&d1=2026-01-26&endDate=2026-01-28&d2=2026-01-28&amenities=POOL)

Family friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-01-26&d1=2026-01-26&endDate=2026-01-28&d2=2026-01-28&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-01-26&d1=2026-01-26&endDate=2026-01-28&d2=2026-01-28&amenities=PETS)

## Check prices for these dates

Tonight

[12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000349349&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[13 Jan - 14 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000349349&startDate=2026-01-13&endDate=2026-01-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000349349&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=3000349349&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for East Prairie hotels

![Laptop workspace, blackout curtains, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/bbf96e9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Charleston/Sikeston East MO

[](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

Charleston

6.8/10

(619 reviews)

"Staff was great! Room was nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lana

£51

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

Sikeston

9.4/10

Exceptional

(1,003 reviews)

"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nicole

£77

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/55808580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/57e73ffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/54eabc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn at Discovery Park of America

[](https://www.expedia.co.uk/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information)

Union City

9.2/10

Wonderful

(330 reviews)

"The rooms are big and the property is spotless!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

debbie

£71

includes taxes & fees

8 Feb - 9 Feb

[](https://www.expedia.co.uk/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/e1e1641a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed, Non Smoking, Microwave | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/c064d51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed, Non Smoking, Microwave | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/73298be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/5a28b168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hospitality House Union City I 69 / US 51

[](https://www.expedia.co.uk/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information)

Union City

6.8/10

(374 reviews)

"Very friendly staff. Upgraded my room to accommodate my first floor request. Room was clean and very comfortable. I would definitely stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barb

£48

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/c970f53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/6140f4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/2feca880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/aadd65c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Union City by IHG

[](https://www.expedia.co.uk/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information)

Union City

9.4/10

Exceptional

(310 reviews)

"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rickey Smith

£92

includes taxes & fees

6 Feb - 7 Feb

[](https://www.expedia.co.uk/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information)

![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/c1609da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/ba65d6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/97ce04e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/643f6c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Union City US 51

[](https://www.expedia.co.uk/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information)

Union City

8.4/10

Very good

(490 reviews)

"Nice room"

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

José Ricardo

£59

includes taxes & fees

8 Feb - 9 Feb

[](https://www.expedia.co.uk/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

[](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

Sikeston

9.0/10

Wonderful

(462 reviews)

"Very clean and super friendly staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katherine

£86

includes taxes & fees

1 Feb - 2 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Free daily full breakfast ](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Sikeston

[](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

Sikeston

8.4/10

Very good

(1,009 reviews)

"Great stay, everything was clean and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charles

£57

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7bc13d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/3fa32ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/d5184d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7397c7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Hearth Inn & Suites Union City

[](https://www.expedia.co.uk/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information)

Union City

8.6/10

Excellent

(551 reviews)

"Roaches!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Teresa

£53

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information)

![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn and Suites by Wyndham Sikeston

[](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

Sikeston

7.2/10

Good

(1,004 reviews)

"Rooms need updated and the breakfast didn’t have much to offer."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bonnie

£53

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/97dfc357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/715f35ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Sikeston/Miner Area

[](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

Sikeston

6.8/10

(580 reviews)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Misty

£50

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, 1 Bedroom, Non Smoking | Bathroom | Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/bathtub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/1d8642af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### New Orleans Inn Portageville 

[](https://www.expedia.co.uk/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information)

Portageville

8.0/10

Very good

(734 reviews)

"Parking was good, staff was great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Corey

[](https://www.expedia.co.uk/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7a78d337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Sikeston I-55

[](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

Sikeston

8.4/10

Very good

(284 reviews)

"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

aileen

£75

includes taxes & fees

17 Jan - 18 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/352edf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Eagle Inn Charleston

[](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information)

Charleston

6.6/10

(105 reviews)

"Middle of nowhere hotel was ok"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

£50

includes taxes & fees

14 Jan - 15 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down duvets, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

[](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

Sikeston

8.6/10

Excellent

(445 reviews)

"Stay was excellent "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kourtney

£79

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Winery](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/d87c89d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/bb2e8b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/a2256dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/e766d35b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### MainStay Suites Union City, TN

[](https://www.expedia.co.uk/Union-City-Hotels-MainStay-Suites.h39519116.Hotel-Information)

Union City

8.6/10

Excellent

(42 reviews)

"Very clean room, friendly staff! I would highly recommend this place! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lydia

£83

includes taxes & fees

14 Jan - 15 Jan

[](https://www.expedia.co.uk/Union-City-Hotels-MainStay-Suites.h39519116.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Accessible (Hearing) | Iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f54017fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/2c1de1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/8df1e765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Union City

[](https://www.expedia.co.uk/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information)

Union City

9.6/10

Exceptional

(168 reviews)

"Staff was great. Room was ready and clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

£91

includes taxes & fees

18 Jan - 19 Jan

[](https://www.expedia.co.uk/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information)

![Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/ef46b494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/e6403655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 By Wyndham Marston

[](https://www.expedia.co.uk/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information)

Marston

8.0/10

Very good

(43 reviews)

"Great hotel, great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dmitry

£48

includes taxes & fees

14 Jan - 15 Jan

[](https://www.expedia.co.uk/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Sikeston

[](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

Sikeston

9.2/10

Wonderful

(48 reviews)

"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

AHMAD

£85

includes taxes & fees

25 Jan - 26 Jan

[](https://www.expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![Individually decorated, individually furnished, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

[](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

Sikeston

8.4/10

Very good

(728 reviews)

"Clean room and easy access to room"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anne

£47

includes taxes & fees

9 Feb - 10 Feb

[](https://www.expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-27&endDate=2026-01-28&regionId=3000349349&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## Stay near popular East Prairie attractions

### Big Oak Tree State Park

3.8/5 (8 reviews)

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532655754)

## Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

[See all hotels in East Prairie](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-27&endDate=2026-01-28&adults=2&regionId=3000349349)

![Bridge over Mississippi River, New Orleans in background](https://images.trvl-media.com/place/6209928/57ec11c5-0aa9-4b04-9ae1-c121ec0bef56.jpg?impolicy=fcrop&w=900&h=292&p=1&q=high)

## Top East Prairie Hotel Reviews

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg)

### Hampton Inn Sikeston

10/10 Excellent

"The room was very clean and nicely appointed. The continental breakfast was good with hot food items and hard boiled eggs, oatmeal, fruit, etc. Price was reasonable. "

[](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![New Orleans Inn Portageville ](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936_y.jpg)

### New Orleans Inn Portageville 

10/10 Excellent

"Parking was good, staff was great "

[](https://expedia.co.uk/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"It was nice a hotel have to come back sometime "

[](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg)

### Pear Tree Inn Sikeston

10/10 Excellent

"Clean and comfy room. Great staff"

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg)

### Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent

"Staff promptly fixed a problem, room smelled very clean."

[](https://expedia.co.uk/Sikeston-Hotels-Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![TownePlace Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/0e9a77e3_y.jpg)

### TownePlace Suites by Marriott Sikeston

10/10 Excellent

"Beautiful new hotel. Great service. The construction must have been rushed or corners were cut. The wallpaper in the bathroom was already bubbling. We had a great stay. "

[](https://expedia.co.uk/Sikeston-Hotels-Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"The room was very nice and the bathroom was very clean. Everything was very nice and the breakfast was good. We were very pleased with everything. I recommend it highly."

[](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent

"Nice man and good hotel"

[](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Reelfoot Lake Inn](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/755237c5_y.jpg)

### Reelfoot Lake Inn

10/10 Excellent

"Homegate Inn is an older property and there is some noticeable wear and tear on the exterior. My room appears to have been updated recently with new bedding and furniture. Had a nice tv with tons of channels. Heat and air worked very well. Plenty of hot water. Room was very clean and comfortable. Nice desk and chair, tv, large fridge with freezer, coffee maker, dresser, large closet. Bath was clean and nice. Check-in was fast and easy. Owner and staff were friendly and attentive. Reelfoot Lake is directly across the street and is a beautiful area. Dining, gas, shopping is closeby, though it is a small town. This was my second stay and I will stay again, I'm sure. "

[](https://expedia.co.uk/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information)

## More cheap stays in East Prairie

![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO

£47

9 Feb - 10 Feb

includes taxes & fees

8.4/10 Very Good! (727 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

£53

9 Feb - 10 Feb

includes taxes & fees

7.2/10 Good! (1,002 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Sikeston

120 S Interstate Drive Sikeston MO

£57

18 Jan - 19 Jan

includes taxes & fees

8.2/10 Very Good! (1,006 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Pear Tree Inn Sikeston](https://images.trvl-media.com/lodging/1000000/20000/19300/19205/ff050f85_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Pear Tree Inn Sikeston

2602 E Malone Avenue Sikeston MO

£64

18 Jan - 19 Jan

includes taxes & fees

9.2/10 Wonderful! (1,000 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information)

![Sleep Inn at Discovery Park of America](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sleep Inn at Discovery Park of America

1111 BLue Heron Lane Union City TN

£71

8 Feb - 9 Feb

includes taxes & fees

9/10 Wonderful! (330 reviews)

[](https://expedia.co.uk/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

£86

1 Feb - 2 Feb

includes taxes & fees

8.8/10 Excellent! (462 reviews)

[](https://expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

## Frequently asked questions

### When is the best time to go to East Prairie?

> From June through August, East Prairie experiences its peak season, drawing in visitors eager to explore the area's natural beauty and vibrant community. This is an ideal time for those who love outdoor activities, as the lush landscapes and scenic parks offer ample opportunities for hiking, biking, and picnicking. The comfortable warmth encourages leisurely strolls through the town and along the lakes, making it a delightful time for sightseeing.
> 
>   
> If you're considering a trip with family or friends, June is particularly lively, with various festivals and events taking place, allowing you to immerse yourself in the local culture and traditions. The friendly atmosphere and the chance to connect with residents can enhance your experience, making your adventure even more memorable.
> 
>   
> For travellers seeking a more budget-friendly option, November presents a great opportunity to explore East Prairie at slightly lower prices. While the weather may be cooler, you can still enjoy the charm of the town and its surroundings, perhaps even embracing the quieter pace of life during this season.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a East Prairie hotel booking with Expedia?

### How much is the nightly rate at a East Prairie hotel?

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