Title: Cheap Car Hire in East Prairie, USA - Expedia.co.uk [East Prairie Travel Guide](https://expedia.co.uk/East-Prairie.dx3000349349)[Hotels in East Prairie](https://expedia.co.uk/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Flights to East Prairie](https://expedia.co.uk/Cheap-Flights-To-East-Prairie.d3000349349.Travel-Guide-Flights)[East Prairie Holidays](https://expedia.co.uk/East-Prairie.d3000349349.Holidays-City-Breaks) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in East Prairie, USA ## Search and Compare from Car Companies in East Prairie ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in East Prairie \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people East Prairie, Missouri, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=East%20Prairie,%20Missouri,%20United%20States%20of%20America&dpln=3000349349&date1=22/02/2026&date2=24/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people East Prairie, Missouri, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=East%20Prairie,%20Missouri,%20United%20States%20of%20America&dpln=3000349349&date1=22/02/2026&date2=24/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people East Prairie, Missouri, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=East%20Prairie,%20Missouri,%20United%20States%20of%20America&dpln=3000349349&date1=22/02/2026&date2=24/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people East Prairie, Missouri, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=East%20Prairie,%20Missouri,%20United%20States%20of%20America&dpln=3000349349&date1=22/02/2026&date2=24/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in East Prairie [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=East%20Prairie,%20Missouri,%20United%20States%20of%20America&dpln=3000349349&date1=22/02/2026&date2=24/02/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_SPRING_PROMO_3000349349) ## Frequently asked questions ### How much is a rental car per day in East Prairie? ### Can I hire a car from Sikeston, MO (SIK-Sikeston Memorial Municipal)? ### What happens if I need to cancel my East Prairie car reservation? ### What types of cars can I rent in East Prairie? ### Where can I go on a road trip from East Prairie? > - Home to sights galore, Memphis is approximately 120 miles from East Prairie. First up on the itinerary? Head for Graceland, one of the city's biggest highlights. > - Around 110 miles away, Clarksville is another location worth adding to your travel itinerary. Check out Austin Peay State University while you're there. > - No visit is complete without spending a day at Missouri Botanical Gardens and Arboretum. This renowned nature spot is approximately 140 miles from East Prairie. Get out into the fresh air and relax! ### How do I find the best car hire deals in East Prairie with Expedia? ### How old do you have to be to hire a car in East Prairie? ### What do you need to hire a car in East Prairie? ### What is the cheapest car hire in East Prairie? ### Can I hire a car for a month or longer in East Prairie? ### Where can I find an East Prairie hire car if I am younger than 25? ### Can I drive in East Prairie with my current driver's license? > - Age restrictions: You'll need to be 25 in most states to be able to hire a car, although in some areas, 21 years and older is allowed. We recommend checking local regulations, and with the hire car company before you travel to understand all the regulations that may apply to you. > - Driving limitations: Read the fine print before you slide behind the wheel so you can avoid any unnecessary charges. When hiring a car in the U.S, it's usually prohibited to cross country borders into Canada or Mexico, drive onto ferries or traverse certain types of rugged terrain with a hire car. Please read the details before you book! ### Why should I rent an East Prairie car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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