A red train on tracks, palm trees, and modern buildings.

Find Spa Hotels in Central San Diego, CA

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Check availability on Central San Diego Spa Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for Central San Diego hotels with a spa

A hotel lobby with leather armchairs, a sofa, and a reception desk.

1. Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
Kearny Mesa
9.2 out of 10, Wonderful, (1,002 reviews)
"Fantastic hotel with very friendly staff"
United States
Jeffrey
The price is £98
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn San Diego-Kearny Mesa
A modern reception desk with a wooden panel backdrop and illuminated signage.

2. TownePlace Suites by Marriott San Diego Central

TownePlace Suites by Marriott San Diego Central
3.0 star property
Kearny Mesa
9.0 out of 10, Wonderful, (644 reviews)
"Great hotel all around!"
United States
Eduardo
The price is £146
includes taxes & fees
20 Nov - 21 Nov
TownePlace Suites by Marriott San Diego Central
An outdoor seating area with wicker chairs and a fire feature.

3. Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
3.0 star property
Kearny Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Great staff, clean rooms and excellent location"
United States
Ahmad
The price is £109
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott San Diego Central
A spacious lobby with a high ceiling, modern furniture, and a fireplace.

4. Four Points by Sheraton San Diego

Four Points by Sheraton San Diego
3.5 star property
Kearny Mesa
8.2 out of 10, Very good, (1,002 reviews)
"Wonderful Weekend, hotel was nice and clean."
United States
Lucy
The price is £124
includes taxes & fees
5 Nov - 6 Nov
Four Points by Sheraton San Diego
A modern hotel with a glass entrance, outdoor seating, and palm trees.

5. Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium
3.0 star property
Kearny Mesa
8.0 out of 10, Very good, (1,008 reviews)
"Overall, our stay was great!"
United States
Willy
The price is £101
includes taxes & fees
8 Nov - 9 Nov
Hilton Garden Inn San Diego Mission Valley Stadium
Room

6. Extended Stay America Suites San Diego Mission Valley Stadium

Extended Stay America Suites San Diego Mission Valley Stadium
2.5 star property
Kearny Mesa
6.6 out of 10, (1,002 reviews)
"Room was clean, staff was great and its in a convenient location."
United States
Brenda
The price is £92
includes taxes & fees
29 Nov - 30 Nov
Extended Stay America Suites San Diego Mission Valley Stadium
A large swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a striped facade.

7. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (2,127 reviews)
"Beautiful hotel with wonderful staff! I have already booked my next stay. I would highly recommend this hotel."
United States
Heather
The price is £230
includes taxes & fees
1 Dec - 2 Dec
Lafayette Hotel & Club
A hotel entrance with a stone archway, a reception desk, and potted plants.

8. Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
Mission Hills
9.2 out of 10, Wonderful, (1,098 reviews)
"The hotel was quite adequate for a night stay before an early flight. Proximity to the airport was key."
United States
JEFFREY
The price is £117
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express San Diego Airport - Old Town by IHG
An outdoor patio with wicker furniture, a stone fire pit, and blue umbrellas.

9. HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
Sorrento Valley
9.2 out of 10, Wonderful, (1,001 reviews)
"Overall great location, staff, and room"
United States
Melissa
The price is £146
includes taxes & fees
15 Nov - 16 Nov
HYATT house San Diego/Sorrento Mesa
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

10. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (237 reviews)
"Friendly staff!"
United States
Donavin
The price is £123
includes taxes & fees
4 Nov - 5 Nov
City24 Hotel Little Italy Mission Hills
An outdoor seating area with a fire feature, white chairs, and potted plants.

11. Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley
3.5 star property
Mission Valley
9.2 out of 10, Wonderful, (1,001 reviews)
"Love the clean room, the set-up and helpful staff"
United States
Paulette
The price is £138
includes taxes & fees
22 Nov - 23 Nov
Springhill Suites San Diego Mission Valley
A neatly made bed with a patterned throw, a small stool, a wall-mounted shelf with plants, and a painting.

12. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,104 reviews)
"We really enjoyed our stay. The pool was great and really enjoyed the bar and staff"
United States
Kathy
The price is £149
includes taxes & fees
22 Nov - 23 Nov
Legacy Resort Hotel & Spa
A living room with a sectional sofa, a wooden coffee table, a blue ottoman, a wooden chair with cushions, a built-in bookshelf, and a stone wall with a fireplace.

13. Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
Sorrento Valley
9.0 out of 10, Wonderful, (1,742 reviews)
"Had a great stay!"
United States
Terrance
The price is £116
includes taxes & fees
22 Nov - 23 Nov
Country Inn & Suites by Radisson, San Diego North, CA
A spacious lobby with a central seating area, a reception desk, and a staircase leading to an upper level.

14. Courtyard by Marriott San Diego Miramar

Courtyard by Marriott San Diego Miramar
3.0 star property
Miramar
8.8 out of 10, Excellent, (1,001 reviews)
"Decent Hotel"
United States
Jignesh
The price is £123
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott San Diego Miramar
An outdoor seating area with sofas, a fire pit, and umbrellas.

15. Homewood Suites by Hilton San Diego Central

Homewood Suites by Hilton San Diego Central
3.0 star property
Scripps Ranch
8.6 out of 10, Excellent, (1,002 reviews)
"Great accommodation"
United States
FERDNAND GERARD
The price is £109
includes taxes & fees
15 Nov - 16 Nov
Homewood Suites by Hilton San Diego Central
A balcony with a table set for breakfast, overlooking a park with trees and a statue.

16. Cosmopolitan Hotel & Restaurant

Cosmopolitan Hotel & Restaurant
2.5 star property
Old Town San Diego
9.2 out of 10, Wonderful, (771 reviews)
"Great atmosphere! Perfect place to enjoy all of Old town San Diego"
United States
Alan
The price is £157
includes taxes & fees
3 Nov - 4 Nov
Cosmopolitan Hotel & Restaurant
A modern lobby with a round table and four chairs, a reception desk, and a large window.

17. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,001 reviews)
"The trolley that's just across the street from the hotel was amazing and convenient!"
United States
Eva
The price is £145
includes taxes & fees
22 Nov - 23 Nov
San Diego Marriott Mission Valley
A poolside area with lounge chairs, a fire pit, and string lights.

18. Hyatt Regency La Jolla

Hyatt Regency La Jolla
4.0 star property
University City
9.0 out of 10, Wonderful, (1,003 reviews)
"Grace was amazing! She helped so much and was so sweet!! Can’t wait to go back and stay there again!"
United States
Priya
The price is £241
includes taxes & fees
5 Nov - 6 Nov
Hyatt Regency La Jolla
Room

19. Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG

Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
2.5 star property
Sorrento Valley
8.8 out of 10, Excellent, (1,001 reviews)
"Solid place to stay"
United States
Johnathan
The price is £120
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
A modern reception area with a stone wall, a blue sofa, and a reception desk.

20. Kings Inn San Diego

Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3,827 reviews)
"Loved this hotel and will be back!"
United States
james
The price is £70
includes taxes & fees
1 Dec - 2 Dec
Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Central San Diego

Pool
Breakfast included

Top Central San Diego Hotel Reviews

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent
"Excellent stay! Can’t wait to be back again!"
Aaron 1-night trip
Posted 7 hours ago
Crowne Plaza San Diego - Mission Valley by IHG

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