Title: TOP Hotels near Museums in Central San Diego, CA for 2026 | Expedia.co.uk [Central San Diego Travel Guide](https://expedia.co.uk/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.co.uk/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Holiday Rentals in Central San Diego](https://expedia.co.uk/Central-San-Diego-Holiday-Rentals.d6056570.Travel-Guide-HolidayRentals)[Flights to Central San Diego](https://expedia.co.uk/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.co.uk/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-San-Diego.d6056570.Car-Hire-Guide)[Central San Diego Holidays](https://expedia.co.uk/Central-San-Diego.d6056570.Holidays-City-Breaks) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels near Museums in Central San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central San Diego Hotels near Museums Tonight [8 Dec - 9 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Dec - 10 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central San Diego Hotels near Museums No exact matches found, but these alternatives could be just right ## Recommended hotels in Central San Diego ![2 outdoor pools, a heated pool, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/2c4c818b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/f03b817a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/01ecd568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Dana on Mission Bay Mission Bay 9.0/10 Wonderful (3910) "Staff was great, room was spotless, and map was easy to follow." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosa £144 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/724f034d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/f15931a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/8399b5a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency La Jolla University City 8.8/10 Excellent (1005) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dru £152 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/8077fd39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/21efa256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/7442075b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa Mission Valley 9.2/10 Wonderful (2955) "Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric £131 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/91baa1e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/a5cb77af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/ade03197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Marina Gateway Hotel National City 9.2/10 Wonderful (3504) "Clean room nice staff right off of the freeway. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olivia £96 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/bc1e5add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/a9d5662a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine ](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7c71b256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Californian cuisine ](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/7fe47de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise Point Resort & Spa Mission Bay 8.6/10 Excellent (2349) "Amazing place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barak Ben £151 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/4a0531e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/77e4221b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/7c98a26c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego/Mission Valley Mission Valley 8.8/10 Excellent (1274) "Spacious and clean rooms, helpful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gholam £86 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/332/771038f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/400/332/e4705932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/332/6ddceb14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel San Diego - Mission Valley Mission Valley 8.4/10 Very good (1392) "Great hotel in a great area - would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bhupinder £98 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/43ae1d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed | Premium bedding, down duvets, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/05adb83a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/6248eb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1990000/1987700/1987617/486f9d1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Mission Valley/Hotel Circle Mission Valley 8.4/10 Very good (1443) "Good place to stay, and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yuke £89 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Courtyard-By-Marriott-San-Diego-Mission-ValleyHotel-Circle.h1987617.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/9101297c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/1de80c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![37-inch flat-screen TV with cable channels, TV, pay films](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3840x5y0-f741e07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Mission Valley Mission Valley 8.0/10 Very good (2235) "Excelente hotel" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Julio £102 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/9de84bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/d7035e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Balcony (Corner) | Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/w4000h2663x0y0-6bec227e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Diego Marriott La Jolla University City 8.6/10 Excellent (2168) "Very nice hotel and clean rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noor £134 includes taxes & fees 12 Dec - 13 Dec [](https://www.expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-22&endDate=2025-12-23®ionId=6056570&adults=2&location_highlights_explore=museums&sort=RECOMMENDED&openPlayBack=true) ## Top Central San Diego Hotel Reviews ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Great convenient spot away from all the traffic madness of the village. Thomas at the front desk was outstanding. $40 parking and $40 breakfasts was ridiculous! " [](https://expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "Professional Staff" [](https://expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Large , clean room" [](https://expedia.co.uk/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](https://images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "Everything was great. The check in, the restaurant was good." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Everything Great !" [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Best Western Inn & Suites San Diego – Zoo/SeaWorld Area ](https://images.trvl-media.com/lodging/1000000/50000/40800/40745/a5f33771_y.jpg) ### Best Western Inn & Suites San Diego – Zoo/SeaWorld Area 10/10 Excellent "Great room and beds" [](https://expedia.co.uk/San-Diego-Hotels-Comfort-Inn-Suites-San-Diego-Zoo-SeaWorld-Area.h40745.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Always pleasant and the best staff ever" [](https://expedia.co.uk/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "Easy check-in and great location for my business. Breakfast was solid and included - always a plus when you're travelling!" [](https://expedia.co.uk/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Front desk staff was kind, knowledgeable and efficient " [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Cars - [Sports Hotels in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Adventure-Sport-Hotel.0-0-d5921-tAdventureSportHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Business-Hotel.0-0-d5921-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Bar in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Hotel-With-A-Bar.0-0-d5921-thotelwithabar.Travel-Guide-Filter-Hotels) - [Hotels with a View in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Hotel-With-A-View.0-0-d5921-thotelwithaview.Travel-Guide-Filter-Hotels) - 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