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Search Business Hotels in Central San Diego

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Check availability on Central San Diego Business Hotels

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Central San Diego business-friendly hotels

A breakfast buffet area with a stone wall, a coffee station, and a fruit display.
A table with two gold-framed lamps and a vase of white flowers.
A hotel lobby with leather armchairs, a sofa, and a reception desk.
An elevator area with stone walls and a potted plant.

1. Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
Kearny Mesa
United States
Jeffrey
£100
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn San Diego-Kearny Mesa
An outdoor patio with a stone fire pit, outdoor seating, string lights, and a tall, narrow heater.
A beach with clear skies, a rocky cliff, and a lighthouse in the distance.
A multi-level hotel lobby with dining areas, a reception desk, and a large TV screen.
A hotel room with a large bed, a chair, a nightstand, and a lamp.

2. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
United States
Kunta
£167
includes taxes & fees
30 Oct - 31 Oct
Embassy Suites by Hilton San Diego La Jolla
An outdoor dining area with tables set for two, string lights overhead, and a view of a building in the background.
A modern interior with a seating area featuring round tables and chairs, a large mirror, and a unique ceiling light fixture.
A spacious lobby with a modern staircase, comfortable seating, and large windows offering natural light.
An outdoor wedding venue with rows of chairs, floral centerpieces, and string lights.

3. Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
Mission Valley
Mexico
LUIS
£112
includes taxes & fees
26 Oct - 27 Oct
Hilton San Diego Mission Valley
A modern hotel with a glass entrance, outdoor seating, and palm trees.
A modern hotel lobby with a sofa, chairs, a coffee table, and a TV.
A modern hotel with a central entrance, large windows, and palm trees.
A hotel room with two beds, a sofa, a desk, and a lamp.

4. Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium
Kearny Mesa
United States
KELLEY
£102
includes taxes & fees
8 Nov - 9 Nov
Hilton Garden Inn San Diego Mission Valley Stadium
A hotel lobby with a waterfall feature, outdoor seating area, and multiple floors with balconies.
A hotel with a large pool area, outdoor seating, and a well-maintained garden.
A bar area with a long counter, multiple stools, and a television screen.
A spacious lobby with two sofas, a reception desk, and a large chandelier.

5. Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
Mission Valley
United States
Thao
£102
includes taxes & fees
26 Oct - 27 Oct
Crowne Plaza San Diego - Mission Valley by IHG
A modern bar area with wooden ceiling beams, bar stools, and a long counter.
A multi-story hotel with a curved facade, balconies, and a central entrance with a glass door.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.
An outdoor seating area with wicker chairs and a fire feature.

6. Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
Kearny Mesa
United States
Marjorie
£120
includes taxes & fees
1 Nov - 2 Nov
Courtyard by Marriott San Diego Central
A pathway flanked by neatly trimmed hedges and a building with a balcony.
A courtyard with a small pond, trees, and a fountain.
A courtyard with a small pond, palm trees, and a building with balconies.
A courtyard with a small water feature surrounded by rocks and greenery.

7. California Suites Hotel

California Suites Hotel
Clairemont
United States
Leo
£65
includes taxes & fees
20 Oct - 21 Oct
California Suites Hotel
A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.
A gym with treadmills, elliptical machines, and a stationary bike.
An outdoor patio area with tables and chairs, red umbrellas, and a view of palm trees and a building with a 'BLW' sign.
A modern hotel lobby with a reception desk, seating area with chairs and a sofa, a ceiling fan, and a large window with curtains.

8. Best Western Seven Seas

Best Western Seven Seas
Mission Valley
United States
Jeffrey
£73
includes taxes & fees
20 Oct - 21 Oct
Best Western Seven Seas
A hotel room with a large bed, a desk with a computer, a red chair, and a view of the city.
A modern hotel lobby with a brick wall, a reception desk, a seating area, and a buffet table.
A bar area with a sign reading 'Fireside Bar & Grill' and various colorful drinks on the counter.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building.

9. Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
Sorrento Valley
United States
Jane
£131
includes taxes & fees
1 Nov - 2 Nov
Country Inn & Suites by Radisson, San Diego North, CA
An outdoor dining area with tables and chairs, a fire feature, and a bar area with a stone wall and shelves.
A spacious gym with various exercise equipment, large windows, and a wooden floor.
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a tall building in the background.
A hotel entrance with a covered outdoor seating area, palm trees, and a car parked in front.

10. San Diego Marriott La Jolla

San Diego Marriott La Jolla
University City
United States
Josh
£160
includes taxes & fees
30 Oct - 31 Oct
San Diego Marriott La Jolla
View all properties

Top Central San Diego Hotel Reviews

California Suites Hotel

California Suites Hotel

10/10 Excellent
"Good"
Juan 3-night trip
Posted 9 hours ago
California Suites Hotel
Handlery Hotel

Handlery Hotel

10/10 Excellent
"The parking was a little confusing on my first time there. Scanning room card at the proper area of the machine."
Brett 2-night trip
Posted 12 hours ago
Handlery Hotel
Pleasant Inn

Pleasant Inn

8/10 Good
"The room was spotless and quite big, with a separate table for two as well as a desk. The bed and pillows were comfy. Staff at check in were lovely. This is a basic motel, with no pool, gym, or vending machines, at least that I found. But things were very clean, the floor was not carpeted (so clean), and very comfortable, with free parking. About 10-15 minutes drive from UCSD, so a good option when hotels nearby are booked or over priced. Walmarts, 99 Ranch, and Starbucks are less than a mile away though driving is recommended as traffic moves quickly."
Tiela 2-night trip
Posted 15 hours ago
Pleasant Inn
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent
"Over all good the ac is amazing !"
Andy 1-night trip
Posted 16 hours ago
Crowne Plaza San Diego - Mission Valley by IHG
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"Very kind staff and the rooms were clean during our stay. The only complaint I have was the fact that the internet was spotty on certain timeframes during my stay. Great location and kind staff. Keep it up Alcala hotel ☺️"
Mike 5-night trip
Posted 18 hours ago
The Alcala Hotel Mission Valley/Seaworld

Frequently asked questions

Why book your business hotel in Central San Diego with Expedia?
Here at Expedia, we make it our job to help you land an ideal stay at the right price. From 5-star corporate-friendly properties to affordable hotels filled with conveniences, you'll have your next work trip organised in a few quick clicks.
How can I find cheap business hotels in Central San Diego?
When you're travelling for work in Central San Diego, our "business friendly" filter will help you find a suitable hotel. From free WiFi and included breakfast to conference spaces and in-room desks, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your preferred star rating and budget to see the most affordable stays.

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